153l - Revision history

OCA at 15:20, 13 March 2024

2024-03-13T15:20:01Z

←Older revision		Revision as of 15:20, 13 March 2024
Line 3:		Line 3:
	<StructureSection load='153l' size='340' side='right'caption='[[153l]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='153l' size='340' side='right'caption='[[153l]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[153l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=153L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[153l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anser_anser_anser Anser anser anser]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=153L FirstGlance]. <br>
-	</td></tr><tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"~~><span class~~=~~'plainlinks'~~>[~~https://en.wikipedia.org/wiki/Lysozyme Lysozyme~~]~~, with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.~~1.~~17 3.2.1.17] </span>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=153l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=153l OCA], [https://pdbe.org/153l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=153l RCSB], [https://www.ebi.ac.uk/pdbsum/153l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=153l ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=153l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=153l OCA], [https://pdbe.org/153l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=153l RCSB], [https://www.ebi.ac.uk/pdbsum/153l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=153l ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/LYG_ANSAN LYG_ANSAN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 17:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=153l ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=153l ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The structure of goose egg-white lysozyme (GEWL) has been refined to an R-value of 15.9% at 1.6 A resolution. Details of the structure determination, the refinement and the structure itself are presented. The structure of a complex of the enzyme with the trisaccharide of N-acetyl glucosamine has also been determined and refined at 1.6 A resolution. The trisaccharide occupies sites analogous to the B, C and D subsites of chicken (HEWL) and phage T4 (T4L) lysozymes. All three lysozymes (GEWL, HEWL and T4L) display the same characteristic set of bridging hydrogen bonds between backbone atoms of the protein and the 2-acetamido group of the saccharide in subsite C. Glu73 of GEWL is seen to correspond closely to Glu35 of HEWL (and to Glu11 of T4L) and supports the established view that this group is critically involved in the catalytic mechanism. There is, however, no obvious residue in goose lysozyme that is a counterpart of Asp52 of chicken lysozyme (or of Asp20 in T4L), suggesting that a second acidic residue is not essential for the catalytic activity of goose lysozyme, and may not be required for the activity of other lysozymes.
-
-	The refined structures of goose lysozyme and its complex with a bound trisaccharide show that the "goose-type" lysozymes lack a catalytic aspartate residue.,Weaver LH, Grutter MG, Matthews BW J Mol Biol. 1995 Jan 6;245(1):54-68. PMID:7823320<ref>PMID:7823320</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 153l" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]		*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Anser anser anser]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Lysozyme]]~~	+	[[Category: Gruetter MG]]
-	[[Category: Gruetter~~, M G~~]]	+	[[Category: Matthews BW]]
-	[[Category: Matthews~~, B W~~]]	+	[[Category: Weaver LH]]
-	[[Category: Weaver~~, L H~~]]	+

OCA at 10:13, 17 February 2021

2021-02-17T10:13:55Z

←Older revision		Revision as of 10:13, 17 February 2021
Line 3:		Line 3:
	<StructureSection load='153l' size='340' side='right'caption='[[153l]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='153l' size='340' side='right'caption='[[153l]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[153l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=153L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[153l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=153L FirstGlance]. <br>
-	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=153l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=153l OCA], [~~http~~://pdbe.org/153l PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=153l RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/153l PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=153l ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=153l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=153l OCA], [https://pdbe.org/153l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=153l RCSB], [https://www.ebi.ac.uk/pdbsum/153l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=153l ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 14:08, 10 May 2019

2019-05-10T14:08:34Z

←Older revision		Revision as of 14:08, 10 May 2019
Line 1:		Line 1:

	==THE REFINED STRUCTURES OF GOOSE LYSOZYME AND ITS COMPLEX WITH A BOUND TRISACCHARIDE SHOW THAT THE "GOOSE-TYPE LYSOZYMES LACK A CATALYTIC ASPARTATE==		==THE REFINED STRUCTURES OF GOOSE LYSOZYME AND ITS COMPLEX WITH A BOUND TRISACCHARIDE SHOW THAT THE "GOOSE-TYPE LYSOZYMES LACK A CATALYTIC ASPARTATE==
-	<StructureSection load='153l' size='340' side='right' caption='[[153l]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='153l' size='340' side='right'caption='[[153l]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[153l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153L FirstGlance]. <br>		<table><tr><td colspan='2'>[[153l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153L FirstGlance]. <br>
Line 11:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/53/153l_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/53/153l_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Gruetter, M G]]		[[Category: Gruetter, M G]]
	[[Category: Matthews, B W]]		[[Category: Matthews, B W]]
	[[Category: Weaver, L H]]		[[Category: Weaver, L H]]

OCA at 09:16, 9 August 2017

2017-08-09T09:16:11Z

←Older revision		Revision as of 09:16, 9 August 2017
Line 1:		Line 1:
		+
	==THE REFINED STRUCTURES OF GOOSE LYSOZYME AND ITS COMPLEX WITH A BOUND TRISACCHARIDE SHOW THAT THE "GOOSE-TYPE LYSOZYMES LACK A CATALYTIC ASPARTATE==		==THE REFINED STRUCTURES OF GOOSE LYSOZYME AND ITS COMPLEX WITH A BOUND TRISACCHARIDE SHOW THAT THE "GOOSE-TYPE LYSOZYMES LACK A CATALYTIC ASPARTATE==
	<StructureSection load='153l' size='340' side='right' caption='[[153l]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='153l' size='340' side='right' caption='[[153l]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[153l]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Ansan Ansan]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[153l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153L FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=153l OCA], [http://pdbe.org/153l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=153l RCSB], [http://www.ebi.ac.uk/pdbsum/153l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=153l OCA], [http://pdbe.org/153l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=153l RCSB], [http://www.ebi.ac.uk/pdbsum/153l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=153l ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=153l ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Ansan]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Gruetter, M G]]		[[Category: Gruetter, M G]]
	[[Category: Matthews, B W]]		[[Category: Matthews, B W]]
	[[Category: Weaver, L H]]		[[Category: Weaver, L H]]

OCA at 15:50, 9 September 2015

2015-09-09T15:50:59Z

←Older revision		Revision as of 15:50, 9 September 2015
Line 2:		Line 2:
	<StructureSection load='153l' size='340' side='right' caption='[[153l]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='153l' size='340' side='right' caption='[[153l]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[153l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Anser_anser_anser Anser anser anser~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[153l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ansan Ansan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153L FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=153l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=153l RCSB], [http://www.ebi.ac.uk/pdbsum/153l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=153l OCA], [http://pdbe.org/153l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=153l RCSB], [http://www.ebi.ac.uk/pdbsum/153l PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 153l" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Anser anser anser~~]]	+	[[Category: Ansan]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Gruetter, M G]]		[[Category: Gruetter, M G]]
	[[Category: Matthews, B W]]		[[Category: Matthews, B W]]
	[[Category: Weaver, L H]]		[[Category: Weaver, L H]]

OCA at 11:30, 22 December 2014

2014-12-22T11:30:46Z

←Older revision		Revision as of 11:30, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[153l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Anser_anser_anser Anser anser anser]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153L FirstGlance]. <br>		<table><tr><td colspan='2'>[[153l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Anser_anser_anser Anser anser anser]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153L FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=153l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=153l RCSB], [http://www.ebi.ac.uk/pdbsum/153l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=153l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=153l RCSB], [http://www.ebi.ac.uk/pdbsum/153l PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	[[Category: Anser anser anser]]		[[Category: Anser anser anser]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
-	[[Category: Gruetter, M G.]]	+	[[Category: Gruetter, M G]]
-	[[Category: Matthews, B W.]]	+	[[Category: Matthews, B W]]
-	[[Category: Weaver, L H.]]	+	[[Category: Weaver, L H]]

OCA at 08:30, 23 July 2014

2014-07-23T08:30:37Z

←Older revision		Revision as of 08:30, 23 July 2014
Line 1:		Line 1:
-	[[~~Image~~:153l.~~png\|left~~\|200px]]	+	==THE REFINED STRUCTURES OF GOOSE LYSOZYME AND ITS COMPLEX WITH A BOUND TRISACCHARIDE SHOW THAT THE "GOOSE-TYPE LYSOZYMES LACK A CATALYTIC ASPARTATE==
		+	<StructureSection load='153l' size='340' side='right' caption='[[153l]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[153l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Anser_anser_anser Anser anser anser]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153L FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=153l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=153l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=153l RCSB], [http://www.ebi.ac.uk/pdbsum/153l PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/53/153l_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The structure of goose egg-white lysozyme (GEWL) has been refined to an R-value of 15.9% at 1.6 A resolution. Details of the structure determination, the refinement and the structure itself are presented. The structure of a complex of the enzyme with the trisaccharide of N-acetyl glucosamine has also been determined and refined at 1.6 A resolution. The trisaccharide occupies sites analogous to the B, C and D subsites of chicken (HEWL) and phage T4 (T4L) lysozymes. All three lysozymes (GEWL, HEWL and T4L) display the same characteristic set of bridging hydrogen bonds between backbone atoms of the protein and the 2-acetamido group of the saccharide in subsite C. Glu73 of GEWL is seen to correspond closely to Glu35 of HEWL (and to Glu11 of T4L) and supports the established view that this group is critically involved in the catalytic mechanism. There is, however, no obvious residue in goose lysozyme that is a counterpart of Asp52 of chicken lysozyme (or of Asp20 in T4L), suggesting that a second acidic residue is not essential for the catalytic activity of goose lysozyme, and may not be required for the activity of other lysozymes.

-	~~{{STRUCTURE_153l\| PDB=153l \| SCENE= }}~~	+	The refined structures of goose lysozyme and its complex with a bound trisaccharide show that the "goose-type" lysozymes lack a catalytic aspartate residue.,Weaver LH, Grutter MG, Matthews BW J Mol Biol. 1995 Jan 6;245(1):54-68. PMID:7823320<ref>PMID:7823320</ref>

-	~~===THE REFINED STRUCTURES OF GOOSE LYSOZYME AND ITS COMPLEX WITH A BOUND TRISACCHARIDE SHOW THAT THE "GOOSE-TYPE LYSOZYMES LACK A CATALYTIC ASPARTATE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_7823320}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[153l]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Anser_anser_anser Anser anser anser]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA].~~	+

	==See Also==		==See Also==
-	*[[~~Hen Egg-White (HEW)~~ Lysozyme\|~~Hen Egg-White (HEW)~~ Lysozyme]]	+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:007823320<~~/~~ref~~><~~ref group="xtra">PMID:014695246</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Anser anser anser]]		[[Category: Anser anser anser]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]

OCA at 21:09, 20 October 2012

2012-10-20T21:09:16Z

←Older revision		Revision as of 21:09, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[153l]] is a 1 chain structure ~~of [[Hen Egg-White (HEW) Lysozyme]]~~ with sequence from [http://en.wikipedia.org/wiki/Anser_anser_anser Anser anser anser]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA].	+	[[153l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Anser_anser_anser Anser anser anser]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA].

	==See Also==		==See Also==
Line 14:		Line 14:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:007823320~~</ref><ref group="xtra">PMID:011917145~~</ref><ref group="xtra">PMID:014695246</ref><references group="xtra"/>	+	<ref group="xtra">PMID:007823320</ref><ref group="xtra">PMID:014695246</ref><references group="xtra"/>
	[[Category: Anser anser anser]]		[[Category: Anser anser anser]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]

OCA at 12:43, 27 July 2012

2012-07-27T12:43:43Z

←Older revision		Revision as of 12:43, 27 July 2012
Line 1:		Line 1:
	[[Image:153l.png\|left\|200px]]		[[Image:153l.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_153l", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_153l\| PDB=153l \| SCENE= }}		{{STRUCTURE_153l\| PDB=153l \| SCENE= }}

	===THE REFINED STRUCTURES OF GOOSE LYSOZYME AND ITS COMPLEX WITH A BOUND TRISACCHARIDE SHOW THAT THE "GOOSE-TYPE LYSOZYMES LACK A CATALYTIC ASPARTATE===		===THE REFINED STRUCTURES OF GOOSE LYSOZYME AND ITS COMPLEX WITH A BOUND TRISACCHARIDE SHOW THAT THE "GOOSE-TYPE LYSOZYMES LACK A CATALYTIC ASPARTATE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_7823320}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 7823320 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_7823320}}		{{ABSTRACT_PUBMED_7823320}}

	==About this Structure==		==About this Structure==
-	[[153l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Anser_anser_anser Anser anser anser]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA].	+	[[153l]] is a 1 chain structure of [[Hen Egg-White (HEW) Lysozyme]] with sequence from [http://en.wikipedia.org/wiki/Anser_anser_anser Anser anser anser]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=153L OCA].

	==See Also==		==See Also==
-	*[[Hen Egg-White (HEW) Lysozyme]]	+	*[[Hen Egg-White (HEW) Lysozyme\|Hen Egg-White (HEW) Lysozyme]]

	==Reference==		==Reference==

OCA: Protected "153l" [edit=sysop:move=sysop]

2011-04-27T11:55:34Z

Protected "153l" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:55, 27 April 2011