1alm - Revision history

OCA at 09:46, 26 May 2021

2021-05-26T09:46:45Z

←Older revision		Revision as of 09:46, 26 May 2021
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	<StructureSection load='1alm' size='340' side='right'caption='[[1alm]]' scene=''>		<StructureSection load='1alm' size='340' side='right'caption='[[1alm]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>The July 2001 RCSB PDB [~~http~~://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Actin'' by David S. Goodsell is [~~http~~://dx.doi.org/10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ALM FirstGlance]. <br>	+	<table><tr><td colspan='2'>The July 2001 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Actin'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ALM FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1alm FirstGlance], [~~http~~://www.ebi.ac.uk/pdbsum/1alm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1alm ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1alm FirstGlance], [https://www.ebi.ac.uk/pdbsum/1alm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1alm ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:15, 21 August 2019

2019-08-21T07:15:38Z

←Older revision		Revision as of 07:15, 21 August 2019
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	==THE STRUCTURE OF THE ACTO-MYOSIN SUBFRAGMENT-ONE COMPLEX. RESULTS OF SEARCHES USING DATA FROM ELECTRON MICROSCOPY AND X-RAY CRYSTALLOGRAPHY. THEORETICAL MODEL, ALPHA CARBONS.==		==THE STRUCTURE OF THE ACTO-MYOSIN SUBFRAGMENT-ONE COMPLEX. RESULTS OF SEARCHES USING DATA FROM ELECTRON MICROSCOPY AND X-RAY CRYSTALLOGRAPHY. THEORETICAL MODEL, ALPHA CARBONS.==
-	<StructureSection load='1alm' size='340' side='right' caption='[[1alm]]' scene=''>	+	<StructureSection load='1alm' size='340' side='right'caption='[[1alm]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>The July 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Actin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ALM FirstGlance]. <br>		<table><tr><td colspan='2'>The July 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Actin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ALM FirstGlance]. <br>
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	[[Category: Theoretical Model]]		[[Category: Theoretical Model]]
	[[Category: Actin]]		[[Category: Actin]]
		+	[[Category: Large Structures]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]
	[[Category: Mendelson, R A]]		[[Category: Mendelson, R A]]
	[[Category: Morris, E P]]		[[Category: Morris, E P]]

OCA at 10:42, 15 November 2017

2017-11-15T10:42:59Z

←Older revision		Revision as of 10:42, 15 November 2017
Line 5:		Line 5:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>The July 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Actin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ALM FirstGlance]. <br>		<table><tr><td colspan='2'>The July 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Actin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ALM FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1alm FirstGlance], [http://www.ebi.ac.uk/pdbsum/1alm PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1alm FirstGlance], [http://www.ebi.ac.uk/pdbsum/1alm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1alm ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:41, 11 February 2016

2016-02-11T08:41:29Z

←Older revision		Revision as of 08:41, 11 February 2016
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		+	{{Theoretical_model}}
		+
	==THE STRUCTURE OF THE ACTO-MYOSIN SUBFRAGMENT-ONE COMPLEX. RESULTS OF SEARCHES USING DATA FROM ELECTRON MICROSCOPY AND X-RAY CRYSTALLOGRAPHY. THEORETICAL MODEL, ALPHA CARBONS.==		==THE STRUCTURE OF THE ACTO-MYOSIN SUBFRAGMENT-ONE COMPLEX. RESULTS OF SEARCHES USING DATA FROM ELECTRON MICROSCOPY AND X-RAY CRYSTALLOGRAPHY. THEORETICAL MODEL, ALPHA CARBONS.==
	<StructureSection load='1alm' size='340' side='right' caption='[[1alm]]' scene=''>		<StructureSection load='1alm' size='340' side='right' caption='[[1alm]]' scene=''>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Theoretical Model]]
	[[Category: Actin]]		[[Category: Actin]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]
	[[Category: Mendelson, R A]]		[[Category: Mendelson, R A]]
	[[Category: Morris, E P]]		[[Category: Morris, E P]]

OCA at 06:49, 11 September 2015

2015-09-11T06:49:28Z

←Older revision		Revision as of 06:49, 11 September 2015
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1alm" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
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	[[Category: Actin]]		[[Category: Actin]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]
		+	[[Category: Mendelson, R A]]
		+	[[Category: Morris, E P]]

OCA at 11:36, 22 December 2014

2014-12-22T11:36:19Z

←Older revision		Revision as of 11:36, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>The July 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Actin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ALM FirstGlance]. <br>		<table><tr><td colspan='2'>The July 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Actin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ALM FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1alm FirstGlance], [http://www.ebi.ac.uk/pdbsum/1alm PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1alm FirstGlance], [http://www.ebi.ac.uk/pdbsum/1alm PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 08:12, 30 July 2014

2014-07-30T08:12:22Z

←Older revision		Revision as of 08:12, 30 July 2014
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-	~~{{Theoretical_model}}~~	+	==THE STRUCTURE OF THE ACTO-MYOSIN SUBFRAGMENT-ONE COMPLEX. RESULTS OF SEARCHES USING DATA FROM ELECTRON MICROSCOPY AND X-RAY CRYSTALLOGRAPHY. THEORETICAL MODEL, ALPHA CARBONS.==
		+	<StructureSection load='1alm' size='340' side='right' caption='[[1alm]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>The July 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Actin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ALM FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1alm FirstGlance], [http://www.ebi.ac.uk/pdbsum/1alm PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Surmises of how myosin subfragment 1 (S1) interacts with actin filaments in muscle contraction rest upon knowing the relative arrangement of the two proteins. Although there exist crystallographic structures for both S1 and actin, as well as electron microscopy data for the acto-S1 complex (AS1), modeling of this arrangement has so far only been done "by eye." Here we report fitted AS1 structures obtained using a quantitative method that is both more objective and makes more complete use of the data. Using undistorted crystallographic results, the best-fit AS1 structure shows significant differences from that obtained by visual fitting. The best fit is produced using the F-actin model of Holmes et al. [Holmes, K. C., Popp, D., Gebhard, W. & Kabsch, W. (1990) Nature (London) 347, 44-49]. S1 residues at the AS1 interface are now found at a higher radius as well as being translated axially and rotated azimuthally. Fits using S1 plus loops missing from the crystal structure were achieved using a homology search method to predict loop structures. These improved fits favor an arrangement in which the loop at the 50- to 20-kDa domain junction of S1 is located near the N terminus of actin. Rigid-body movements of the lower 50-kDa domain, which further improve the fit, produce closure of the large 50-kDa domain cleft and bring conserved residues in the lower 50-kDa domain into an apparently appropriate orientation for close interaction with actin. This finding supports the idea that binding of ATP to AS1 at the end of the ATPase cycle disrupts the actin binding site by changing the conformation of the 50-kDa cleft of S1.

-	~~[[Image~~:~~1alm~~.~~png\|left\|200px]]~~	+	The structure of the acto-myosin subfragment 1 complex: results of searches using data from electron microscopy and x-ray crystallography.,Mendelson R, Morris EP Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8533-8. PMID:9238011<ref>PMID:9238011</ref>

-	~~{{STRUCTURE_1alm\| PDB=1alm \| SCENE= }}~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~===THE STRUCTURE OF THE ACTO-MYOSIN SUBFRAGMENT-ONE COMPLEX. RESULTS OF SEARCHES USING DATA FROM ELECTRON MICROSCOPY AND X-RAY CRYSTALLOGRAPHY. THEORETICAL MODEL~~, ~~ALPHA CARBONS.===~~	+	== References ==
-		+	<references/>
-	~~{{ABSTRACT_PUBMED_9238011}}~~	+	__TOC__
-		+	</StructureSection>
-	~~==About this Structure==~~	+
-	~~The July 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule~~ of the ~~Month] feature on ''Actin'' by David~~ S. ~~Goodsell is [http://dx~~.~~doi.org~~/~~10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:009238011<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Actin]]		[[Category: Actin]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]

OCA: Protected "1alm" [edit=sysop:move=sysop]

2012-10-21T09:36:02Z

Protected "1alm" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:36, 21 October 2012

OCA at 09:36, 21 October 2012

2012-10-21T09:36:00Z

←Older revision		Revision as of 09:36, 21 October 2012
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	{{Theoretical_model}}		{{Theoretical_model}}
-	~~{{Seed}}~~	+
	[[Image:1alm.png\|left\|200px]]		[[Image:1alm.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1alm", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1alm\| PDB=1alm \| SCENE= }}		{{STRUCTURE_1alm\| PDB=1alm \| SCENE= }}

	===THE STRUCTURE OF THE ACTO-MYOSIN SUBFRAGMENT-ONE COMPLEX. RESULTS OF SEARCHES USING DATA FROM ELECTRON MICROSCOPY AND X-RAY CRYSTALLOGRAPHY. THEORETICAL MODEL, ALPHA CARBONS.===		===THE STRUCTURE OF THE ACTO-MYOSIN SUBFRAGMENT-ONE COMPLEX. RESULTS OF SEARCHES USING DATA FROM ELECTRON MICROSCOPY AND X-RAY CRYSTALLOGRAPHY. THEORETICAL MODEL, ALPHA CARBONS.===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_9238011}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 9238011 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_9238011}}		{{ABSTRACT_PUBMED_9238011}}

	==About this Structure==		==About this Structure==
-	The July 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Actin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ALM OCA~~].	+	The July 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Actin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~9238011~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:009238011</ref><references group="xtra"/>
	[[Category: Actin]]		[[Category: Actin]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 09:01:13 2010''

OCA at 07:01, 21 January 2010

2010-01-21T07:01:15Z

←Older revision		Revision as of 07:01, 21 January 2010
Line 1:		Line 1:
-	~~'''Theoretical Model'''~~	+	{{Theoretical_model}}
		+	{{Seed}}
		+	[[Image:1alm.png\|left\|200px]]

-	~~The entry 1ALM is a Theoretical Model titled 'THE STRUCTURE OF THE ACTO~~-~~MYOSIN SUBFRAGMENT~~-~~ONE COMPLEX~~. ~~RESULTS OF SEARCHES USING DATA FROM ELECTRON MICROSCOPY AND X-RAY CRYSTALLOGRAPHY. THEORETICAL MODEL~~, ~~ALPHA CARBONS.'~~.	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_1alm", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_1alm\| PDB=1alm \| SCENE= }}

-	~~[[Category:Theoretical Model]]~~	+	===THE STRUCTURE OF THE ACTO-MYOSIN SUBFRAGMENT-ONE COMPLEX. RESULTS OF SEARCHES USING DATA FROM ELECTRON MICROSCOPY AND X-RAY CRYSTALLOGRAPHY. THEORETICAL MODEL, ALPHA CARBONS.===


-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 30~~ 09:48:~~47 2008~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_9238011}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 9238011 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_9238011}}
		+
		+	==About this Structure==
		+	The July 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Actin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_7 10.2210/rcsb_pdb/mom_2001_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ALM OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:9238011</ref><references group="xtra"/>
		+	[[Category: Actin]]
		+	[[Category: RCSB PDB Molecule of the Month]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 09:01:13 2010''