1b40 - Revision history

OCA at 05:36, 9 August 2023

2023-08-09T05:36:00Z

←Older revision		Revision as of 05:36, 9 August 2023
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	<StructureSection load='1b40' size='340' side='right'caption='[[1b40]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1b40' size='340' side='right'caption='[[1b40]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B40 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B40 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [https://pdbe.org/1b40 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [https://www.ebi.ac.uk/pdbsum/1b40 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b40 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [https://pdbe.org/1b40 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [https://www.ebi.ac.uk/pdbsum/1b40 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b40 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/OPPA_SALTY OPPA_SALTY]] This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.	+	[https://www.uniprot.org/uniprot/OPPA_SALTY OPPA_SALTY] This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Tame, J R~~.H]]	+	[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-	[[Category: ~~Wilkinson, A J~~]]	+	[[Category: Tame JRH]]
-	[[Category: ~~Peptide binding protein]]~~	+	[[Category: Wilkinson AJ]]
-	~~[[Category: Peptide transport~~]]	+

OCA at 15:04, 2 June 2021

2021-06-02T15:04:10Z

←Older revision		Revision as of 15:04, 2 June 2021
Line 3:		Line 3:
	<StructureSection load='1b40' size='340' side='right'caption='[[1b40]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1b40' size='340' side='right'caption='[[1b40]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1B40 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B40 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [~~http~~://pdbe.org/1b40 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1b40 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1b40 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [https://pdbe.org/1b40 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [https://www.ebi.ac.uk/pdbsum/1b40 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b40 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/OPPA_SALTY OPPA_SALTY]] This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.	+	[[https://www.uniprot.org/uniprot/OPPA_SALTY OPPA_SALTY]] This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[~~Oligopeptide-binding protein~~\|~~Oligopeptide-binding protein~~]]	+	*[[ABC transporter 3D structures\|ABC transporter 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:44, 28 August 2019

2019-08-28T16:44:33Z

←Older revision		Revision as of 16:44, 28 August 2019
Line 1:		Line 1:

	==OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KFK==		==OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KFK==
-	<StructureSection load='1b40' size='340' side='right' caption='[[1b40]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='1b40' size='340' side='right'caption='[[1b40]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B40 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B40 FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b4/1b40_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b4/1b40_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1b40" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1b40" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Oligopeptide-binding protein\|Oligopeptide-binding protein]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Tame, J R.H]]		[[Category: Tame, J R.H]]
	[[Category: Wilkinson, A J]]		[[Category: Wilkinson, A J]]
	[[Category: Peptide binding protein]]		[[Category: Peptide binding protein]]
	[[Category: Peptide transport]]		[[Category: Peptide transport]]

OCA at 11:09, 22 November 2017

2017-11-22T11:09:47Z

←Older revision		Revision as of 11:09, 22 November 2017
Line 1:		Line 1:
		+
	==OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KFK==		==OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KFK==
	<StructureSection load='1b40' size='340' side='right' caption='[[1b40]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1b40' size='340' side='right' caption='[[1b40]], [[Resolution\|resolution]] 2.20Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B40 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B40 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [http://pdbe.org/1b40 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [http://www.ebi.ac.uk/pdbsum/1b40 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [http://pdbe.org/1b40 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [http://www.ebi.ac.uk/pdbsum/1b40 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1b40 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1b40" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1b40" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Oligopeptide-binding protein\|Oligopeptide-binding protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 01:11, 8 February 2016

2016-02-08T01:11:42Z

←Older revision		Revision as of 01:11, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1b40 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:29, 10 September 2015

2015-09-10T06:29:39Z

←Older revision		Revision as of 06:29, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1b40' size='340' side='right' caption='[[1b40]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1b40' size='340' side='right' caption='[[1b40]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B40 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B40 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OPPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [http://pdbe.org/1b40 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [http://www.ebi.ac.uk/pdbsum/1b40 PDBsum]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [http://www.ebi.ac.uk/pdbsum/1b40 PDBsum]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1b40" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Tame, J R.H]]		[[Category: Tame, J R.H]]
	[[Category: Wilkinson, A J]]		[[Category: Wilkinson, A J]]
	[[Category: Peptide binding protein]]		[[Category: Peptide binding protein]]
	[[Category: Peptide transport]]		[[Category: Peptide transport]]

OCA at 19:29, 24 December 2014

2014-12-24T19:29:02Z

←Older revision		Revision as of 19:29, 24 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [http://www.ebi.ac.uk/pdbsum/1b40 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [http://www.ebi.ac.uk/pdbsum/1b40 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/OPPA_SALTY OPPA_SALTY]] This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 11:55, 22 December 2014

2014-12-22T11:55:57Z

←Older revision		Revision as of 11:55, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B40 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B40 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OPPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OPPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [http://www.ebi.ac.uk/pdbsum/1b40 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [http://www.ebi.ac.uk/pdbsum/1b40 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
-	[[Category: Tame, J R.H.]]	+	[[Category: Tame, J R.H]]
-	[[Category: Wilkinson, A J.]]	+	[[Category: Wilkinson, A J]]
	[[Category: Peptide binding protein]]		[[Category: Peptide binding protein]]
	[[Category: Peptide transport]]		[[Category: Peptide transport]]

OCA at 03:12, 7 August 2014

2014-08-07T03:12:58Z

←Older revision		Revision as of 03:12, 7 August 2014
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-	[[~~Image:~~1b40.~~png~~\|~~left~~\|200px]]	+	==OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KFK==
		+	<StructureSection load='1b40' size='340' side='right' caption='[[1b40]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1b40]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B40 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OPPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b40 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b40 RCSB], [http://www.ebi.ac.uk/pdbsum/1b40 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b4/1b40_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Isothermal titration calorimetry has been used to study the binding of 20 different peptides to the peptide binding protein OppA, and the crystal structures of the ligand complexes have been refined. This periplasmic binding protein, part of the oligopeptide permease system of Gram negative bacteria, has evolved to bind and enclose small peptides of widely varying sequences. The peptides used in this study have the sequence Lys-X-Lys, where X is any of the 20 commonly occurring amino acids. The various side-chains found at position 2 on the ligand fit into a hydrated pocket. The majority of side-chains are restrained to particular conformations within the pocket. Water molecules act as flexible adapters, matching the hydrogen-bonding requirements of the protein and ligand and shielding charges on the buried ligand. This use of water by OppA to broaden the repertoire of its binding site is not unique, but contrasts sharply with other proteins which use water to help bind ligands highly selectively. Predicting the thermodynamics of binding from the structure of the complexes is highly complicated by the influence of water on the system.

-	~~{{STRUCTURE_1b40\| PDB=1b40 \| SCENE= }}~~	+	Crystallographic and calorimetric analysis of peptide binding to OppA protein.,Sleigh SH, Seavers PR, Wilkinson AJ, Ladbury JE, Tame JR J Mol Biol. 1999 Aug 13;291(2):393-415. PMID:10438628<ref>PMID:10438628</ref>

-	~~===OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KFK===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10438628}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1b40]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Salmonella_enterica_subsp~~.~~_enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA].~~	+

	==See Also==		==See Also==
	*[[Oligopeptide-binding protein\|Oligopeptide-binding protein]]		*[[Oligopeptide-binding protein\|Oligopeptide-binding protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:010438628<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Tame, J R.H.]]		[[Category: Tame, J R.H.]]

OCA at 08:24, 20 October 2012

2012-10-20T08:24:35Z

←Older revision		Revision as of 08:24, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1b40]] is a 2 chain structure ~~of [[Oligopeptide-binding protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA].	+	[[1b40]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B40 OCA].

	==See Also==		==See Also==