1bih - Revision history

OCA at 15:33, 13 March 2024

2024-03-13T15:33:09Z

←Older revision		Revision as of 15:33, 13 March 2024
Line 3:		Line 3:
	<StructureSection load='1bih' size='340' side='right'caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='1bih' size='340' side='right'caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Cecropia_moth Cecropia moth~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BIH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hyalophora_cecropia Hyalophora cecropia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BIH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.1Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [https://pdbe.org/1bih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [https://www.ebi.ac.uk/pdbsum/1bih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bih ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [https://pdbe.org/1bih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [https://www.ebi.ac.uk/pdbsum/1bih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bih ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/HEMO_HYACE HEMO_HYACE]] Insect-immune protein. Forms a protein complex at the bacterial surface. Can inhibit hemocyte aggregation.	+	[https://www.uniprot.org/uniprot/HEMO_HYACE HEMO_HYACE] Insect-immune protein. Forms a protein complex at the bacterial surface. Can inhibit hemocyte aggregation.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 19:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bih ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bih ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Hemolin, an insect immunoglobulin superfamily member, is a lipopolysaccharide-binding immune protein induced during bacterial infection. The 3.1 angstrom crystal structure reveals a bound phosphate and patches of positive charge, which may represent the lipopolysaccharide binding site, and a new and unexpected arrangement of four immunoglobulin-like domains forming a horseshoe. Sequence analysis and analytical ultracentrifugation suggest that the domain arrangement is a feature of the L1 family of neural cell adhesion molecules related to hemolin. These results are relevant to interpretation of human L1 mutations in neurological diseases and suggest a domain swapping model for how L1 family proteins mediate homophilic adhesion.
-
-	Crystal structure of hemolin: a horseshoe shape with implications for homophilic adhesion.,Su XD, Gastinel LN, Vaughn DE, Faye I, Poon P, Bjorkman PJ Science. 1998 Aug 14;281(5379):991-5. PMID:9703515<ref>PMID:9703515</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1bih" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cecropia moth~~]]	+	[[Category: Hyalophora cecropia]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bjorkman~~, P J~~]]	+	[[Category: Bjorkman PJ]]
-	[[Category: Faye, I]]	+	[[Category: Faye I]]
-	[[Category: Gastinel~~, L N~~]]	+	[[Category: Gastinel LN]]
-	[[Category: Poon, P]]	+	[[Category: Poon P]]
-	[[Category: Su, X D]]	+	[[Category: Su X-D]]
-	[[Category: Vaughn~~, D E]]~~	+	[[Category: Vaughn DE]]
-	~~[[Category: Homophilic adhesion]]~~	+
-	~~[[Category: Insect immunity]]~~	+
-	~~[[Category: Lps-binding~~]]	+

OCA at 09:49, 15 September 2021

2021-09-15T09:49:17Z

←Older revision		Revision as of 09:49, 15 September 2021
Line 3:		Line 3:
	<StructureSection load='1bih' size='340' side='right'caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='1bih' size='340' side='right'caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Cecropia_moth Cecropia moth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1BIH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cecropia_moth Cecropia moth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BIH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [~~http~~://pdbe.org/1bih PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1bih PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1bih ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [https://pdbe.org/1bih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [https://www.ebi.ac.uk/pdbsum/1bih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bih ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/HEMO_HYACE HEMO_HYACE]] Insect-immune protein. Forms a protein complex at the bacterial surface. Can inhibit hemocyte aggregation.	+	[[https://www.uniprot.org/uniprot/HEMO_HYACE HEMO_HYACE]] Insect-immune protein. Forms a protein complex at the bacterial surface. Can inhibit hemocyte aggregation.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 19:44, 11 December 2019

2019-12-11T19:44:39Z

←Older revision		Revision as of 19:44, 11 December 2019
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF THE INSECT IMMUNE PROTEIN HEMOLIN: A NEW DOMAIN ARRANGEMENT WITH IMPLICATIONS FOR HOMOPHILIC ADHESION==		==CRYSTAL STRUCTURE OF THE INSECT IMMUNE PROTEIN HEMOLIN: A NEW DOMAIN ARRANGEMENT WITH IMPLICATIONS FOR HOMOPHILIC ADHESION==
-	<StructureSection load='1bih' size='340' side='right' caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>	+	<StructureSection load='1bih' size='340' side='right'caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cecropia_moth Cecropia moth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BIH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cecropia_moth Cecropia moth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BIH FirstGlance]. <br>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Cecropia moth]]		[[Category: Cecropia moth]]
		+	[[Category: Large Structures]]
	[[Category: Bjorkman, P J]]		[[Category: Bjorkman, P J]]
	[[Category: Faye, I]]		[[Category: Faye, I]]

OCA at 05:24, 8 March 2018

2018-03-08T05:24:35Z

←Older revision		Revision as of 05:24, 8 March 2018
Line 3:		Line 3:
	<StructureSection load='1bih' size='340' side='right' caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='1bih' size='340' side='right' caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BIH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cecropia_moth Cecropia moth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BIH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [http://pdbe.org/1bih PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [http://www.ebi.ac.uk/pdbsum/1bih PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bih ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [http://pdbe.org/1bih PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [http://www.ebi.ac.uk/pdbsum/1bih PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bih ProSAT]</span></td></tr>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/1bih_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/1bih_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Cecropia moth]]
	[[Category: Bjorkman, P J]]		[[Category: Bjorkman, P J]]
	[[Category: Faye, I]]		[[Category: Faye, I]]

OCA at 06:15, 17 August 2017

2017-08-17T06:15:38Z

←Older revision		Revision as of 06:15, 17 August 2017
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF THE INSECT IMMUNE PROTEIN HEMOLIN: A NEW DOMAIN ARRANGEMENT WITH IMPLICATIONS FOR HOMOPHILIC ADHESION==		==CRYSTAL STRUCTURE OF THE INSECT IMMUNE PROTEIN HEMOLIN: A NEW DOMAIN ARRANGEMENT WITH IMPLICATIONS FOR HOMOPHILIC ADHESION==
	<StructureSection load='1bih' size='340' side='right' caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='1bih' size='340' side='right' caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Cecropia_moth Cecropia moth]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BIH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BIH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [http://pdbe.org/1bih PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [http://www.ebi.ac.uk/pdbsum/1bih PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [http://pdbe.org/1bih PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [http://www.ebi.ac.uk/pdbsum/1bih PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bih ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bih ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Cecropia moth]]
	[[Category: Bjorkman, P J]]		[[Category: Bjorkman, P J]]
	[[Category: Faye, I]]		[[Category: Faye, I]]

OCA at 08:06, 11 September 2015

2015-09-11T08:06:16Z

←Older revision		Revision as of 08:06, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1bih' size='340' side='right' caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='1bih' size='340' side='right' caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Hyalophora_cecropia Hyalophora cecropia~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BIH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cecropia_moth Cecropia moth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BIH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [http://www.ebi.ac.uk/pdbsum/1bih PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [http://pdbe.org/1bih PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [http://www.ebi.ac.uk/pdbsum/1bih PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1bih" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Hyalophora cecropia~~]]	+	[[Category: Cecropia moth]]
	[[Category: Bjorkman, P J]]		[[Category: Bjorkman, P J]]
	[[Category: Faye, I]]		[[Category: Faye, I]]

OCA at 13:38, 25 December 2014

2014-12-25T13:38:33Z

←Older revision		Revision as of 13:38, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [http://www.ebi.ac.uk/pdbsum/1bih PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [http://www.ebi.ac.uk/pdbsum/1bih PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HEMO_HYACE HEMO_HYACE]] Insect-immune protein. Forms a protein complex at the bacterial surface. Can inhibit hemocyte aggregation.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 09:20, 22 December 2014

2014-12-22T09:20:20Z

←Older revision		Revision as of 09:20, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hyalophora_cecropia Hyalophora cecropia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BIH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hyalophora_cecropia Hyalophora cecropia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BIH FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [http://www.ebi.ac.uk/pdbsum/1bih PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [http://www.ebi.ac.uk/pdbsum/1bih PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Hyalophora cecropia]]		[[Category: Hyalophora cecropia]]
-	[[Category: Bjorkman, P J.]]	+	[[Category: Bjorkman, P J]]
-	[[Category: Faye, I.]]	+	[[Category: Faye, I]]
-	[[Category: Gastinel, L N.]]	+	[[Category: Gastinel, L N]]
-	[[Category: Poon, P.]]	+	[[Category: Poon, P]]
-	[[Category: Su, X D.]]	+	[[Category: Su, X D]]
-	[[Category: Vaughn, D E.]]	+	[[Category: Vaughn, D E]]
	[[Category: Homophilic adhesion]]		[[Category: Homophilic adhesion]]
	[[Category: Insect immunity]]		[[Category: Insect immunity]]
	[[Category: Lps-binding]]		[[Category: Lps-binding]]

OCA at 09:46, 13 August 2014

2014-08-13T09:46:39Z

←Older revision		Revision as of 09:46, 13 August 2014
Line 1:		Line 1:
-	[[~~Image~~:1bih.~~png\|left~~\|200px]]	+	==CRYSTAL STRUCTURE OF THE INSECT IMMUNE PROTEIN HEMOLIN: A NEW DOMAIN ARRANGEMENT WITH IMPLICATIONS FOR HOMOPHILIC ADHESION==
		+	<StructureSection load='1bih' size='340' side='right' caption='[[1bih]], [[Resolution\|resolution]] 3.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1bih]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hyalophora_cecropia Hyalophora cecropia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BIH FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bih OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bih RCSB], [http://www.ebi.ac.uk/pdbsum/1bih PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/1bih_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Hemolin, an insect immunoglobulin superfamily member, is a lipopolysaccharide-binding immune protein induced during bacterial infection. The 3.1 angstrom crystal structure reveals a bound phosphate and patches of positive charge, which may represent the lipopolysaccharide binding site, and a new and unexpected arrangement of four immunoglobulin-like domains forming a horseshoe. Sequence analysis and analytical ultracentrifugation suggest that the domain arrangement is a feature of the L1 family of neural cell adhesion molecules related to hemolin. These results are relevant to interpretation of human L1 mutations in neurological diseases and suggest a domain swapping model for how L1 family proteins mediate homophilic adhesion.

-	~~{{STRUCTURE_1bih\| PDB=1bih \| SCENE= }}~~	+	Crystal structure of hemolin: a horseshoe shape with implications for homophilic adhesion.,Su XD, Gastinel LN, Vaughn DE, Faye I, Poon P, Bjorkman PJ Science. 1998 Aug 14;281(5379):991-5. PMID:9703515<ref>PMID:9703515</ref>

-	~~===CRYSTAL STRUCTURE OF THE INSECT IMMUNE PROTEIN HEMOLIN: A NEW DOMAIN ARRANGEMENT WITH IMPLICATIONS FOR HOMOPHILIC ADHESION===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_9703515}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1bih]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Hyalophora_cecropia Hyalophora cecropia]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1BIH OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:009703515<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Hyalophora cecropia]]		[[Category: Hyalophora cecropia]]
	[[Category: Bjorkman, P J.]]		[[Category: Bjorkman, P J.]]

OCA: Protected "1bih" [edit=sysop:move=sysop]

2012-10-21T20:50:17Z

Protected "1bih" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:50, 21 October 2012