1bxd - Revision history

OCA at 23:22, 27 December 2023

2023-12-27T23:22:24Z

←Older revision		Revision as of 23:22, 27 December 2023
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	==NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ==		==NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ==
-	<StructureSection load='1bxd' size='340' side='right'caption='[[1bxd~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='1bxd' size='340' side='right'caption='[[1bxd]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecobd Ecobd~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BXD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BXD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [https://pdbe.org/1bxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [https://www.ebi.ac.uk/pdbsum/1bxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bxd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [https://pdbe.org/1bxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [https://www.ebi.ac.uk/pdbsum/1bxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bxd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ENVZ_ECOLI ENVZ_ECOLI]] Member of the two-component regulatory system EnvZ/OmpR involved in the regulation of osmoregulation (genes ompF and ompC). EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals.	+	[https://www.uniprot.org/uniprot/ENVZ_ECOLI ENVZ_ECOLI] Member of the two-component regulatory system EnvZ/OmpR involved in the regulation of osmoregulation (genes ompF and ompC). EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Ecobd]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Dutta, R]]	+	[[Category: Dutta R]]
-	[[Category: Ikura, M]]	+	[[Category: Ikura M]]
-	[[Category: Inouye, M]]	+	[[Category: Inouye M]]
-	[[Category: Ishima, R]]	+	[[Category: Ishima R]]
-	[[Category: Kainosho, M]]	+	[[Category: Kainosho M]]
-	[[Category: Liu, D]]	+	[[Category: Liu D]]
-	[[Category: Ono~~, A M~~]]	+	[[Category: Ono AM]]
-	[[Category: Park, H]]	+	[[Category: Park H]]
-	[[Category: Qin, L]]	+	[[Category: Qin L]]
-	[[Category: Saha~~, S K~~]]	+	[[Category: Saha SK]]
-	[[Category: Swindells~~, M B~~]]	+	[[Category: Swindells MB]]
-	[[Category: Tanaka, T]]	+	[[Category: Tanaka T]]
-	[[Category: Tomomori, C]]	+	[[Category: Tomomori C]]
-	[[Category: Tong~~, K I~~]]	+	[[Category: Tong KI]]
-	[[Category: Yamazaki, T]]	+	[[Category: Yamazaki T]]
-	~~[[Category: His-asp phosphorelay system]]~~	+
-	~~[[Category: Histidine kinase]]~~	+
-	~~[[Category: Osmosensor]]~~	+
-	~~[[Category: Signal transduction]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 10:30, 16 February 2022

2022-02-16T10:30:29Z

←Older revision		Revision as of 10:30, 16 February 2022
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	<StructureSection load='1bxd' size='340' side='right'caption='[[1bxd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1bxd' size='340' side='right'caption='[[1bxd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BXD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecobd Ecobd]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BXD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [https://pdbe.org/1bxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [https://www.ebi.ac.uk/pdbsum/1bxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bxd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [https://pdbe.org/1bxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [https://www.ebi.ac.uk/pdbsum/1bxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bxd ProSAT]</span></td></tr>
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Ecobd]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Dutta, R]]		[[Category: Dutta, R]]

OCA at 07:03, 24 February 2021

2021-02-24T07:03:11Z

←Older revision		Revision as of 07:03, 24 February 2021
Line 3:		Line 3:
	<StructureSection load='1bxd' size='340' side='right'caption='[[1bxd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1bxd' size='340' side='right'caption='[[1bxd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1BXD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BXD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [~~http~~://pdbe.org/1bxd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1bxd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1bxd ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [https://pdbe.org/1bxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [https://www.ebi.ac.uk/pdbsum/1bxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bxd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ENVZ_ECOLI ENVZ_ECOLI]] Member of the two-component regulatory system EnvZ/OmpR involved in the regulation of osmoregulation (genes ompF and ompC). EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals.	+	[[https://www.uniprot.org/uniprot/ENVZ_ECOLI ENVZ_ECOLI]] Member of the two-component regulatory system EnvZ/OmpR involved in the regulation of osmoregulation (genes ompF and ompC). EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:59, 21 May 2019

2019-05-21T08:59:08Z

←Older revision		Revision as of 08:59, 21 May 2019
Line 1:		Line 1:

	==NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ==		==NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ==
-	<StructureSection load='1bxd' size='340' side='right' caption='[[1bxd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='1bxd' size='340' side='right'caption='[[1bxd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BXD FirstGlance]. <br>		<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BXD FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bx/1bxd_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bx/1bxd_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Dutta, R]]		[[Category: Dutta, R]]
	[[Category: Ikura, M]]		[[Category: Ikura, M]]

OCA at 06:17, 17 August 2017

2017-08-17T06:17:52Z

←Older revision		Revision as of 06:17, 17 August 2017
Line 1:		Line 1:
		+
	==NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ==		==NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ==
	<StructureSection load='1bxd' size='340' side='right' caption='[[1bxd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1bxd' size='340' side='right' caption='[[1bxd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BXD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BXD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [http://pdbe.org/1bxd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [http://www.ebi.ac.uk/pdbsum/1bxd PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [http://pdbe.org/1bxd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [http://www.ebi.ac.uk/pdbsum/1bxd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bxd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bxd ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Ecobd]]
	[[Category: Dutta, R]]		[[Category: Dutta, R]]
	[[Category: Ikura, M]]		[[Category: Ikura, M]]

OCA at 13:00, 11 September 2015

2015-09-11T13:00:09Z

←Older revision		Revision as of 13:00, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1bxd' size='340' side='right' caption='[[1bxd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1bxd' size='340' side='right' caption='[[1bxd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli_bl21(de3) Escherichia coli bl21(de3)~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BXD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BXD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [http://www.ebi.ac.uk/pdbsum/1bxd PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [http://pdbe.org/1bxd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [http://www.ebi.ac.uk/pdbsum/1bxd PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1bxd" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Ecobd]]
	[[Category: Dutta, R]]		[[Category: Dutta, R]]
	[[Category: Ikura, M]]		[[Category: Ikura, M]]

OCA at 16:47, 25 December 2014

2014-12-25T16:47:21Z

←Older revision		Revision as of 16:47, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [http://www.ebi.ac.uk/pdbsum/1bxd PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [http://www.ebi.ac.uk/pdbsum/1bxd PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ENVZ_ECOLI ENVZ_ECOLI]] Member of the two-component regulatory system EnvZ/OmpR involved in the regulation of osmoregulation (genes ompF and ompC). EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 11:45, 22 December 2014

2014-12-22T11:45:46Z

←Older revision		Revision as of 11:45, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bl21(de3) Escherichia coli bl21(de3)]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BXD FirstGlance]. <br>		<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bl21(de3) Escherichia coli bl21(de3)]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BXD FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [http://www.ebi.ac.uk/pdbsum/1bxd PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [http://www.ebi.ac.uk/pdbsum/1bxd PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Dutta, R.]]	+	[[Category: Dutta, R]]
-	[[Category: Ikura, M.]]	+	[[Category: Ikura, M]]
-	[[Category: Inouye, M.]]	+	[[Category: Inouye, M]]
-	[[Category: Ishima, R.]]	+	[[Category: Ishima, R]]
-	[[Category: Kainosho, M.]]	+	[[Category: Kainosho, M]]
-	[[Category: Liu, D.]]	+	[[Category: Liu, D]]
-	[[Category: Ono, A M.]]	+	[[Category: Ono, A M]]
-	[[Category: Park, H.]]	+	[[Category: Park, H]]
-	[[Category: Qin, L.]]	+	[[Category: Qin, L]]
-	[[Category: Saha, S K.]]	+	[[Category: Saha, S K]]
-	[[Category: Swindells, M B.]]	+	[[Category: Swindells, M B]]
-	[[Category: Tanaka, T.]]	+	[[Category: Tanaka, T]]
-	[[Category: Tomomori, C.]]	+	[[Category: Tomomori, C]]
-	[[Category: Tong, K I.]]	+	[[Category: Tong, K I]]
-	[[Category: Yamazaki, T.]]	+	[[Category: Yamazaki, T]]
	[[Category: His-asp phosphorelay system]]		[[Category: His-asp phosphorelay system]]
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]

OCA at 09:48, 13 August 2014

2014-08-13T09:48:17Z

←Older revision		Revision as of 09:48, 13 August 2014
Line 1:		Line 1:
-	[[~~Image~~:1bxd.~~png\|left~~\|200px]]	+	==NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ==
		+	<StructureSection load='1bxd' size='340' side='right' caption='[[1bxd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1bxd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bl21(de3) Escherichia coli bl21(de3)]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BXD FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bxd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bxd RCSB], [http://www.ebi.ac.uk/pdbsum/1bxd PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bx/1bxd_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacteria live in capricious environments, in which they must continuously sense external conditions in order to adjust their shape, motility and physiology. The histidine-aspartate phosphorelay signal-transduction system (also known as the two-component system) is important in cellular adaptation to environmental changes in both prokaryotes and lower eukaryotes. In this system, protein histidine kinases function as sensors and signal transducers. The Escherichia coli osmosensor, EnvZ, is a transmembrane protein with histidine kinase activity in its cytoplasmic region. The cytoplasmic region contains two functional domains: domain A (residues 223-289) contains the conserved histidine residue (H243), a site of autophosphorylation as well as transphosphorylation to the conserved D55 residue of response regulator OmpR, whereas domain B (residues 290-450) encloses several highly conserved regions (G1, G2, F and N boxes) and is able to phosphorylate H243. Here we present the solution structure of domain B, the catalytic core of EnvZ. This core has a novel protein kinase structure, distinct from the serine/threonine/tyrosine kinase fold, with unanticipated similarities to both heatshock protein 90 and DNA gyrase B.

-	~~{{STRUCTURE_1bxd\| PDB=1bxd \| SCENE= }}~~	+	NMR structure of the histidine kinase domain of the E. coli osmosensor EnvZ.,Tanaka T, Saha SK, Tomomori C, Ishima R, Liu D, Tong KI, Park H, Dutta R, Qin L, Swindells MB, Yamazaki T, Ono AM, Kainosho M, Inouye M, Ikura M Nature. 1998 Nov 5;396(6706):88-92. PMID:9817206<ref>PMID:9817206</ref>

-	~~===NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_9817206}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1bxd]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli_bl21(de3) Escherichia coli bl21(de3)]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1BXD OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:009817206<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Dutta, R.]]		[[Category: Dutta, R.]]
	[[Category: Ikura, M.]]		[[Category: Ikura, M.]]

OCA: Protected "1bxd" [edit=sysop:move=sysop]

2012-10-21T20:23:46Z

Protected "1bxd" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:23, 21 October 2012