1coo - Revision history

OCA at 15:41, 13 March 2024

2024-03-13T15:41:13Z

←Older revision		Revision as of 15:41, 13 March 2024
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	==THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT==		==THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT==
-	<StructureSection load='1coo' size='340' side='right'caption='[[1coo~~]], [[NMR_Ensembles_of_Models \| 1 NMR models~~]]' scene=''>	+	<StructureSection load='1coo' size='340' side='right'caption='[[1coo]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1COO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1COO FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [https://pdbe.org/1coo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [https://www.ebi.ac.uk/pdbsum/1coo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1coo ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [https://pdbe.org/1coo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [https://www.ebi.ac.uk/pdbsum/1coo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1coo ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]	+	[https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1coo ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1coo ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The structure of the carboxyl-terminal domain of the Escherichia coli RNA polymerase alpha subunit (alpha CTD), which is regarded as the contact site for transcription activator proteins and for the promoter UP element, was determined by nuclear magnetic resonance spectroscopy. Its compact structure of four helices and two long arms enclosing its hydrophobic core shows a folding topology distinct from those of other DNA-binding proteins. The UP element binding site was found on the surface comprising helix 1, the amino-terminal end of helix 4, and the preceding loop. Mutation experiments indicated that the contact sites for transcription activator proteins are also on the same surface.
-
-	Solution structure of the activator contact domain of the RNA polymerase alpha subunit.,Jeon YH, Negishi T, Shirakawa M, Yamazaki T, Fujita N, Ishihama A, Kyogoku Y Science. 1995 Dec 1;270(5241):1495-7. PMID:7491496<ref>PMID:7491496</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1coo" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[RNA polymerase 3D structures\|RNA polymerase 3D structures]]		*[[RNA polymerase 3D structures\|RNA polymerase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Fujita, N]]	+	[[Category: Fujita N]]
-	[[Category: Ishihama, A]]	+	[[Category: Ishihama A]]
-	[[Category: Jeon~~, Y H~~]]	+	[[Category: Jeon YH]]
-	[[Category: Kyogoku, Y]]	+	[[Category: Kyogoku Y]]
-	[[Category: Negishi, T]]	+	[[Category: Negishi T]]
-	[[Category: Shirakawa, M]]	+	[[Category: Shirakawa M]]
-	[[Category: Yamazaki, T]]	+	[[Category: Yamazaki T]]
-	~~[[Category: Nucleotidyl transferase]]~~	+
-	~~[[Category: Transcription regulation~~]]	+

OCA at 05:43, 28 April 2021

2021-04-28T05:43:57Z

←Older revision		Revision as of 05:43, 28 April 2021
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	<StructureSection load='1coo' size='340' side='right'caption='[[1coo]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='1coo' size='340' side='right'caption='[[1coo]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1COO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1COO FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [~~http~~://pdbe.org/1coo PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1coo PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1coo ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [https://pdbe.org/1coo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [https://www.ebi.ac.uk/pdbsum/1coo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1coo ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]	+	[[https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[RNA polymerase\|RNA polymerase]]	+	*[[RNA polymerase 3D structures\|RNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:23, 24 July 2019

2019-07-24T09:23:14Z

←Older revision		Revision as of 09:23, 24 July 2019
Line 1:		Line 1:

	==THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT==		==THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT==
-	<StructureSection load='1coo' size='340' side='right' caption='[[1coo]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>	+	<StructureSection load='1coo' size='340' side='right'caption='[[1coo]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1COO FirstGlance]. <br>		<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1COO FirstGlance]. <br>
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/1coo_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/1coo_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 27:
	</div>		</div>
	<div class="pdbe-citations 1coo" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1coo" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[RNA polymerase\|RNA polymerase]]
	== References ==		== References ==
	<references/>		<references/>
Line 32:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Ecoli]]		[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Fujita, N]]		[[Category: Fujita, N]]
	[[Category: Ishihama, A]]		[[Category: Ishihama, A]]

OCA at 10:36, 18 October 2017

2017-10-18T10:36:27Z

←Older revision		Revision as of 10:36, 18 October 2017
Line 1:		Line 1:
		+
	==THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT==		==THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT==
	<StructureSection load='1coo' size='340' side='right' caption='[[1coo]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='1coo' size='340' side='right' caption='[[1coo]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1COO FirstGlance]. <br>		<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1COO FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [http://pdbe.org/1coo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [http://www.ebi.ac.uk/pdbsum/1coo PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [http://pdbe.org/1coo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [http://www.ebi.ac.uk/pdbsum/1coo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1coo ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1coo ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	</div>		</div>
	<div class="pdbe-citations 1coo" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1coo" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[RNA polymerase\|RNA polymerase]]
-	*[[Temp1\|Temp1]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:56, 11 September 2015

2015-09-11T16:56:09Z

←Older revision		Revision as of 16:56, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1coo' size='340' side='right' caption='[[1coo]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='1coo' size='340' side='right' caption='[[1coo]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli_k-12 Escherichia coli k-12~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1COO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1COO FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [http://www.ebi.ac.uk/pdbsum/1coo PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [http://pdbe.org/1coo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [http://www.ebi.ac.uk/pdbsum/1coo PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1coo" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[RNA polymerase\|RNA polymerase]]		*[[RNA polymerase\|RNA polymerase]]
		+	*[[Temp1\|Temp1]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia coli k-12~~]]	+	[[Category: Ecoli]]
	[[Category: Fujita, N]]		[[Category: Fujita, N]]
	[[Category: Ishihama, A]]		[[Category: Ishihama, A]]

OCA at 19:17, 25 December 2014

2014-12-25T19:17:42Z

←Older revision		Revision as of 19:17, 25 December 2014
Line 5:		Line 5:
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [http://www.ebi.ac.uk/pdbsum/1coo PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [http://www.ebi.ac.uk/pdbsum/1coo PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 18:46, 22 December 2014

2014-12-22T18:46:58Z

←Older revision		Revision as of 18:46, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1COO FirstGlance]. <br>		<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1COO FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [http://www.ebi.ac.uk/pdbsum/1coo PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [http://www.ebi.ac.uk/pdbsum/1coo PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
-	[[Category: Fujita, N.]]	+	[[Category: Fujita, N]]
-	[[Category: Ishihama, A.]]	+	[[Category: Ishihama, A]]
-	[[Category: Jeon, Y H.]]	+	[[Category: Jeon, Y H]]
-	[[Category: Kyogoku, Y.]]	+	[[Category: Kyogoku, Y]]
-	[[Category: Negishi, T.]]	+	[[Category: Negishi, T]]
-	[[Category: Shirakawa, M.]]	+	[[Category: Shirakawa, M]]
-	[[Category: Yamazaki, T.]]	+	[[Category: Yamazaki, T]]
	[[Category: Nucleotidyl transferase]]		[[Category: Nucleotidyl transferase]]
	[[Category: Transcription regulation]]		[[Category: Transcription regulation]]

OCA at 09:12, 27 August 2014

2014-08-27T09:12:48Z

←Older revision		Revision as of 09:12, 27 August 2014
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-	[[~~Image~~:1coo.~~png\|left~~\|200px]]	+	==THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT==
		+	<StructureSection load='1coo' size='340' side='right' caption='[[1coo]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1COO FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [http://www.ebi.ac.uk/pdbsum/1coo PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/1coo_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The structure of the carboxyl-terminal domain of the Escherichia coli RNA polymerase alpha subunit (alpha CTD), which is regarded as the contact site for transcription activator proteins and for the promoter UP element, was determined by nuclear magnetic resonance spectroscopy. Its compact structure of four helices and two long arms enclosing its hydrophobic core shows a folding topology distinct from those of other DNA-binding proteins. The UP element binding site was found on the surface comprising helix 1, the amino-terminal end of helix 4, and the preceding loop. Mutation experiments indicated that the contact sites for transcription activator proteins are also on the same surface.

-	~~{{STRUCTURE_1coo\| PDB=1coo \| SCENE= }}~~	+	Solution structure of the activator contact domain of the RNA polymerase alpha subunit.,Jeon YH, Negishi T, Shirakawa M, Yamazaki T, Fujita N, Ishihama A, Kyogoku Y Science. 1995 Dec 1;270(5241):1495-7. PMID:7491496<ref>PMID:7491496</ref>

-	~~===THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_7491496}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1coo]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA].~~	+

	==See Also==		==See Also==
	*[[RNA polymerase\|RNA polymerase]]		*[[RNA polymerase\|RNA polymerase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:007491496<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
-	[[Category: Escherichia coli]]	+	</StructureSection>
		+	[[Category: Escherichia coli k-12]]
	[[Category: Fujita, N.]]		[[Category: Fujita, N.]]
	[[Category: Ishihama, A.]]		[[Category: Ishihama, A.]]

OCA at 20:27, 20 October 2012

2012-10-20T20:27:35Z

←Older revision		Revision as of 20:27, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1coo]] is a 1 chain structure ~~of [[RNA polymerase]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA].	+	[[1coo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA].

	==See Also==		==See Also==

OCA: Protected "1coo" [edit=sysop:move=sysop]

2012-07-27T10:33:04Z

Protected "1coo" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:33, 27 July 2012