1cwc - Revision history

OCA at 15:44, 13 March 2024

2024-03-13T15:44:00Z

←Older revision		Revision as of 15:44, 13 March 2024
Line 3:		Line 3:
	<StructureSection load='1cwc' size='340' side='right'caption='[[1cwc]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='1cwc' size='340' side='right'caption='[[1cwc]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CWC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Tolypocladium_inflatum Tolypocladium inflatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CWC FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non~~-~~Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNL:4,N-DIMETHYLNORLEUCINE'>MNL</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.86Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1bck\|1bck]], [[1c5f\|1c5f]], [[1csa\|1csa]], [[1cwa\|1cwa]], [[1cwb\|1cwb]], [[1cwf\|1cwf]], [[1cwh\|1cwh]], [[1cwi\|1cwi]], [[1cwj\|1cwj]], [[1cwk\|1cwk]], [[1cwl\|1cwl]], [[1cwm\|1cwm]], [[1cwo\|1cwo]], [[1cya\|1cya]], [[1cyb\|1cyb]], [[1cyn\|1cyn]], [[1ikf\|1ikf]], [[1m63\|1m63]], [[1mf8\|1mf8]], [[1mik\|1mik]], [[1qng\|1qng]], [[1qnh\|1qnh]], [[1xq7\|1xq7]], [[2esl\|2esl]], [[2oju\|2oju]], [[2poy\|2poy]], [[2rma\|2rma]], [[2rmb\|2rmb]], [[2rmc\|2rmc]], [[2wfj\|2wfj]], [[2x2c\|2x2c]], [[2x7k\|2x7k]], [[2z6w\|2z6w]], [[3bo7\|3bo7]], [[3cys\|3cys]], [[3eov\|3eov]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNL:4,N-DIMETHYLNORLEUCINE'>MNL</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwc OCA], [https://pdbe.org/1cwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cwc RCSB], [https://www.ebi.ac.uk/pdbsum/1cwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cwc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwc OCA], [https://pdbe.org/1cwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cwc RCSB], [https://www.ebi.ac.uk/pdbsum/1cwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cwc ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Peptidylprolyl isomerase~~]]	+	[[Category: Tolypocladium inflatum]]
-	[[Category: Mikol, V]]	+	[[Category: Mikol V]]
-	~~[[Category: Cyclophilin]]~~	+
-	~~[[Category: Cyclophilin-cyclosporin complex]]~~	+
-	~~[[Category: Cyclosporin some]]~~	+
-	~~[[Category: Immunosuppressant]]~~	+
-	~~[[Category: Isomerase-immunosuppressant complex~~]]	+

OCA at 15:19, 3 March 2021

2021-03-03T15:19:45Z

←Older revision		Revision as of 15:19, 3 March 2021
Line 3:		Line 3:
	<StructureSection load='1cwc' size='340' side='right'caption='[[1cwc]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='1cwc' size='340' side='right'caption='[[1cwc]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1CWC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CWC FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNL:4,N-DIMETHYLNORLEUCINE'>MNL</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNL:4,N-DIMETHYLNORLEUCINE'>MNL</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bck\|1bck]], [[1c5f\|1c5f]], [[1csa\|1csa]], [[1cwa\|1cwa]], [[1cwb\|1cwb]], [[1cwf\|1cwf]], [[1cwh\|1cwh]], [[1cwi\|1cwi]], [[1cwj\|1cwj]], [[1cwk\|1cwk]], [[1cwl\|1cwl]], [[1cwm\|1cwm]], [[1cwo\|1cwo]], [[1cya\|1cya]], [[1cyb\|1cyb]], [[1cyn\|1cyn]], [[1ikf\|1ikf]], [[1m63\|1m63]], [[1mf8\|1mf8]], [[1mik\|1mik]], [[1qng\|1qng]], [[1qnh\|1qnh]], [[1xq7\|1xq7]], [[2esl\|2esl]], [[2oju\|2oju]], [[2poy\|2poy]], [[2rma\|2rma]], [[2rmb\|2rmb]], [[2rmc\|2rmc]], [[2wfj\|2wfj]], [[2x2c\|2x2c]], [[2x7k\|2x7k]], [[2z6w\|2z6w]], [[3bo7\|3bo7]], [[3cys\|3cys]], [[3eov\|3eov]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1bck\|1bck]], [[1c5f\|1c5f]], [[1csa\|1csa]], [[1cwa\|1cwa]], [[1cwb\|1cwb]], [[1cwf\|1cwf]], [[1cwh\|1cwh]], [[1cwi\|1cwi]], [[1cwj\|1cwj]], [[1cwk\|1cwk]], [[1cwl\|1cwl]], [[1cwm\|1cwm]], [[1cwo\|1cwo]], [[1cya\|1cya]], [[1cyb\|1cyb]], [[1cyn\|1cyn]], [[1ikf\|1ikf]], [[1m63\|1m63]], [[1mf8\|1mf8]], [[1mik\|1mik]], [[1qng\|1qng]], [[1qnh\|1qnh]], [[1xq7\|1xq7]], [[2esl\|2esl]], [[2oju\|2oju]], [[2poy\|2poy]], [[2rma\|2rma]], [[2rmb\|2rmb]], [[2rmc\|2rmc]], [[2wfj\|2wfj]], [[2x2c\|2x2c]], [[2x7k\|2x7k]], [[2z6w\|2z6w]], [[3bo7\|3bo7]], [[3cys\|3cys]], [[3eov\|3eov]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1cwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwc OCA], [~~http~~://pdbe.org/1cwc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1cwc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1cwc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1cwc ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwc OCA], [https://pdbe.org/1cwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cwc RCSB], [https://www.ebi.ac.uk/pdbsum/1cwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cwc ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:02, 29 May 2019

2019-05-29T07:02:55Z

←Older revision		Revision as of 07:02, 29 May 2019
Line 1:		Line 1:

	==IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN==		==IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN==
-	<StructureSection load='1cwc' size='340' side='right' caption='[[1cwc]], [[Resolution\|resolution]] 1.86Å' scene=''>	+	<StructureSection load='1cwc' size='340' side='right'caption='[[1cwc]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CWC FirstGlance]. <br>		<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CWC FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cw/1cwc_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cw/1cwc_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 21:		Line 21:

	==See Also==		==See Also==
-	*[[Cyclophilin\|Cyclophilin]]	+	*[[Cyclophilin 3D structures\|Cyclophilin 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Peptidylprolyl isomerase]]		[[Category: Peptidylprolyl isomerase]]
	[[Category: Mikol, V]]		[[Category: Mikol, V]]

OCA at 11:15, 24 August 2017

2017-08-24T11:15:13Z

←Older revision		Revision as of 11:15, 24 August 2017
Line 1:		Line 1:
		+
	==IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN==		==IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN==
	<StructureSection load='1cwc' size='340' side='right' caption='[[1cwc]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='1cwc' size='340' side='right' caption='[[1cwc]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Human Human]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CWC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CWC FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNL:4,N-DIMETHYLNORLEUCINE'>MNL</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNL:4,N-DIMETHYLNORLEUCINE'>MNL</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bck\|1bck]], [[1c5f\|1c5f]], [[1csa\|1csa]], [[1cwa\|1cwa]], [[1cwb\|1cwb]], [[1cwf\|1cwf]], [[1cwh\|1cwh]], [[1cwi\|1cwi]], [[1cwj\|1cwj]], [[1cwk\|1cwk]], [[1cwl\|1cwl]], [[1cwm\|1cwm]], [[1cwo\|1cwo]], [[1cya\|1cya]], [[1cyb\|1cyb]], [[1cyn\|1cyn]], [[1ikf\|1ikf]], [[1m63\|1m63]], [[1mf8\|1mf8]], [[1mik\|1mik]], [[1qng\|1qng]], [[1qnh\|1qnh]], [[1xq7\|1xq7]], [[2esl\|2esl]], [[2oju\|2oju]], [[2poy\|2poy]], [[2rma\|2rma]], [[2rmb\|2rmb]], [[2rmc\|2rmc]], [[2wfj\|2wfj]], [[2x2c\|2x2c]], [[2x7k\|2x7k]], [[2z6w\|2z6w]], [[3bo7\|3bo7]], [[3cys\|3cys]], [[3eov\|3eov]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bck\|1bck]], [[1c5f\|1c5f]], [[1csa\|1csa]], [[1cwa\|1cwa]], [[1cwb\|1cwb]], [[1cwf\|1cwf]], [[1cwh\|1cwh]], [[1cwi\|1cwi]], [[1cwj\|1cwj]], [[1cwk\|1cwk]], [[1cwl\|1cwl]], [[1cwm\|1cwm]], [[1cwo\|1cwo]], [[1cya\|1cya]], [[1cyb\|1cyb]], [[1cyn\|1cyn]], [[1ikf\|1ikf]], [[1m63\|1m63]], [[1mf8\|1mf8]], [[1mik\|1mik]], [[1qng\|1qng]], [[1qnh\|1qnh]], [[1xq7\|1xq7]], [[2esl\|2esl]], [[2oju\|2oju]], [[2poy\|2poy]], [[2rma\|2rma]], [[2rmb\|2rmb]], [[2rmc\|2rmc]], [[2wfj\|2wfj]], [[2x2c\|2x2c]], [[2x7k\|2x7k]], [[2z6w\|2z6w]], [[3bo7\|3bo7]], [[3cys\|3cys]], [[3eov\|3eov]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CYCLOPHILIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwc OCA], [http://pdbe.org/1cwc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1cwc RCSB], [http://www.ebi.ac.uk/pdbsum/1cwc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwc OCA], [http://pdbe.org/1cwc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1cwc RCSB], [http://www.ebi.ac.uk/pdbsum/1cwc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1cwc ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cwc ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

Line 24:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Human]]
	[[Category: Peptidylprolyl isomerase]]		[[Category: Peptidylprolyl isomerase]]
	[[Category: Mikol, V]]		[[Category: Mikol, V]]

OCA at 11:17, 11 September 2015

2015-09-11T11:17:25Z

←Older revision		Revision as of 11:17, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1cwc' size='340' side='right' caption='[[1cwc]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='1cwc' size='340' side='right' caption='[[1cwc]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CWC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CWC FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNL:4,N-DIMETHYLNORLEUCINE'>MNL</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNL:4,N-DIMETHYLNORLEUCINE'>MNL</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bck\|1bck]], [[1c5f\|1c5f]], [[1csa\|1csa]], [[1cwa\|1cwa]], [[1cwb\|1cwb]], [[1cwf\|1cwf]], [[1cwh\|1cwh]], [[1cwi\|1cwi]], [[1cwj\|1cwj]], [[1cwk\|1cwk]], [[1cwl\|1cwl]], [[1cwm\|1cwm]], [[1cwo\|1cwo]], [[1cya\|1cya]], [[1cyb\|1cyb]], [[1cyn\|1cyn]], [[1ikf\|1ikf]], [[1m63\|1m63]], [[1mf8\|1mf8]], [[1mik\|1mik]], [[1qng\|1qng]], [[1qnh\|1qnh]], [[1xq7\|1xq7]], [[2esl\|2esl]], [[2oju\|2oju]], [[2poy\|2poy]], [[2rma\|2rma]], [[2rmb\|2rmb]], [[2rmc\|2rmc]], [[2wfj\|2wfj]], [[2x2c\|2x2c]], [[2x7k\|2x7k]], [[2z6w\|2z6w]], [[3bo7\|3bo7]], [[3cys\|3cys]], [[3eov\|3eov]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bck\|1bck]], [[1c5f\|1c5f]], [[1csa\|1csa]], [[1cwa\|1cwa]], [[1cwb\|1cwb]], [[1cwf\|1cwf]], [[1cwh\|1cwh]], [[1cwi\|1cwi]], [[1cwj\|1cwj]], [[1cwk\|1cwk]], [[1cwl\|1cwl]], [[1cwm\|1cwm]], [[1cwo\|1cwo]], [[1cya\|1cya]], [[1cyb\|1cyb]], [[1cyn\|1cyn]], [[1ikf\|1ikf]], [[1m63\|1m63]], [[1mf8\|1mf8]], [[1mik\|1mik]], [[1qng\|1qng]], [[1qnh\|1qnh]], [[1xq7\|1xq7]], [[2esl\|2esl]], [[2oju\|2oju]], [[2poy\|2poy]], [[2rma\|2rma]], [[2rmb\|2rmb]], [[2rmc\|2rmc]], [[2wfj\|2wfj]], [[2x2c\|2x2c]], [[2x7k\|2x7k]], [[2z6w\|2z6w]], [[3bo7\|3bo7]], [[3cys\|3cys]], [[3eov\|3eov]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CYCLOPHILIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CYCLOPHILIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cwc RCSB], [http://www.ebi.ac.uk/pdbsum/1cwc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwc OCA], [http://pdbe.org/1cwc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1cwc RCSB], [http://www.ebi.ac.uk/pdbsum/1cwc PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Peptidylprolyl isomerase]]		[[Category: Peptidylprolyl isomerase]]
	[[Category: Mikol, V]]		[[Category: Mikol, V]]

OCA at 19:21, 22 December 2014

2014-12-22T19:21:59Z

←Older revision		Revision as of 19:21, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CWC FirstGlance]. <br>		<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CWC FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNL:4,N-DIMETHYLNORLEUCINE'>MNL</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNL:4,N-DIMETHYLNORLEUCINE'>MNL</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bck\|1bck]], [[1c5f\|1c5f]], [[1csa\|1csa]], [[1cwa\|1cwa]], [[1cwb\|1cwb]], [[1cwf\|1cwf]], [[1cwh\|1cwh]], [[1cwi\|1cwi]], [[1cwj\|1cwj]], [[1cwk\|1cwk]], [[1cwl\|1cwl]], [[1cwm\|1cwm]], [[1cwo\|1cwo]], [[1cya\|1cya]], [[1cyb\|1cyb]], [[1cyn\|1cyn]], [[1ikf\|1ikf]], [[1m63\|1m63]], [[1mf8\|1mf8]], [[1mik\|1mik]], [[1qng\|1qng]], [[1qnh\|1qnh]], [[1xq7\|1xq7]], [[2esl\|2esl]], [[2oju\|2oju]], [[2poy\|2poy]], [[2rma\|2rma]], [[2rmb\|2rmb]], [[2rmc\|2rmc]], [[2wfj\|2wfj]], [[2x2c\|2x2c]], [[2x7k\|2x7k]], [[2z6w\|2z6w]], [[3bo7\|3bo7]], [[3cys\|3cys]], [[3eov\|3eov]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bck\|1bck]], [[1c5f\|1c5f]], [[1csa\|1csa]], [[1cwa\|1cwa]], [[1cwb\|1cwb]], [[1cwf\|1cwf]], [[1cwh\|1cwh]], [[1cwi\|1cwi]], [[1cwj\|1cwj]], [[1cwk\|1cwk]], [[1cwl\|1cwl]], [[1cwm\|1cwm]], [[1cwo\|1cwo]], [[1cya\|1cya]], [[1cyb\|1cyb]], [[1cyn\|1cyn]], [[1ikf\|1ikf]], [[1m63\|1m63]], [[1mf8\|1mf8]], [[1mik\|1mik]], [[1qng\|1qng]], [[1qnh\|1qnh]], [[1xq7\|1xq7]], [[2esl\|2esl]], [[2oju\|2oju]], [[2poy\|2poy]], [[2rma\|2rma]], [[2rmb\|2rmb]], [[2rmc\|2rmc]], [[2wfj\|2wfj]], [[2x2c\|2x2c]], [[2x7k\|2x7k]], [[2z6w\|2z6w]], [[3bo7\|3bo7]], [[3cys\|3cys]], [[3eov\|3eov]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CYCLOPHILIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CYCLOPHILIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cwc RCSB], [http://www.ebi.ac.uk/pdbsum/1cwc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cwc RCSB], [http://www.ebi.ac.uk/pdbsum/1cwc PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 26:		Line 26:
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Peptidylprolyl isomerase]]		[[Category: Peptidylprolyl isomerase]]
-	[[Category: Mikol, V.]]	+	[[Category: Mikol, V]]
	[[Category: Cyclophilin]]		[[Category: Cyclophilin]]
	[[Category: Cyclophilin-cyclosporin complex]]		[[Category: Cyclophilin-cyclosporin complex]]

OCA at 04:09, 3 October 2014

2014-10-03T04:09:37Z

←Older revision		Revision as of 04:09, 3 October 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1cwc\| PDB=1cwc \| SCENE= }}~~	+	==IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN==
-	===IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN===	+	<StructureSection load='1cwc' size='340' side='right' caption='[[1cwc]], [[Resolution\|resolution]] 1.86Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1cwc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CWC FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNL:4,N-DIMETHYLNORLEUCINE'>MNL</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bck\|1bck]], [[1c5f\|1c5f]], [[1csa\|1csa]], [[1cwa\|1cwa]], [[1cwb\|1cwb]], [[1cwf\|1cwf]], [[1cwh\|1cwh]], [[1cwi\|1cwi]], [[1cwj\|1cwj]], [[1cwk\|1cwk]], [[1cwl\|1cwl]], [[1cwm\|1cwm]], [[1cwo\|1cwo]], [[1cya\|1cya]], [[1cyb\|1cyb]], [[1cyn\|1cyn]], [[1ikf\|1ikf]], [[1m63\|1m63]], [[1mf8\|1mf8]], [[1mik\|1mik]], [[1qng\|1qng]], [[1qnh\|1qnh]], [[1xq7\|1xq7]], [[2esl\|2esl]], [[2oju\|2oju]], [[2poy\|2poy]], [[2rma\|2rma]], [[2rmb\|2rmb]], [[2rmc\|2rmc]], [[2wfj\|2wfj]], [[2x2c\|2x2c]], [[2x7k\|2x7k]], [[2z6w\|2z6w]], [[3bo7\|3bo7]], [[3cys\|3cys]], [[3eov\|3eov]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CYCLOPHILIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cwc RCSB], [http://www.ebi.ac.uk/pdbsum/1cwc PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cw/1cwc_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

-	==~~About this Structure~~==	+	==See Also==
-	[[~~1cwc~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA].	+	*[[Cyclophilin\|Cyclophilin]]
-		+	__TOC__
-	~~==Reference==~~	+	</StructureSection>
-	~~<ref group="xtra">PMID:007966126</ref><references group="xtra"/>~~<~~references~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Peptidylprolyl isomerase]]		[[Category: Peptidylprolyl isomerase]]

OCA at 07:35, 30 June 2013

2013-06-30T07:35:15Z

←Older revision		Revision as of 07:35, 30 June 2013
Line 1:		Line 1:
-	[[Image:1cwc.png\|left\|200px]]
-
	{{STRUCTURE_1cwc\| PDB=1cwc \| SCENE= }}		{{STRUCTURE_1cwc\| PDB=1cwc \| SCENE= }}
-
	===IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN===		===IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN===
-

	==About this Structure==		==About this Structure==
	[[1cwc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA].		[[1cwc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA].
-
-	==See Also==
-	*[[Cyclophilin\|Cyclophilin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:007966126</ref><~~ref~~ group="xtra"~~>PMID:015299416<~~/~~ref><ref group="xtra">PMID:008263916</ref><ref group="xtra">PMID:008421501</ref~~><references ~~group="xtra"~~/>	+	<ref group="xtra">PMID:007966126</ref><references group="xtra"/><references/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Peptidylprolyl isomerase]]		[[Category: Peptidylprolyl isomerase]]

OCA at 18:29, 20 October 2012

2012-10-20T18:29:24Z

←Older revision		Revision as of 18:29, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[1cwc]] is a 2 chain structure ~~of [[Cyclophilin]]~~ with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA].	+	[[1cwc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWC OCA].

	==See Also==		==See Also==
Line 13:		Line 13:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:007966126</ref><ref group="xtra">PMID:015299416~~</ref><ref group="xtra">PMID:008073029~~</ref><ref group="xtra">PMID:008263916</ref><ref group="xtra">PMID:008421501</ref><references group="xtra"/>	+	<ref group="xtra">PMID:007966126</ref><ref group="xtra">PMID:015299416</ref><ref group="xtra">PMID:008263916</ref><ref group="xtra">PMID:008421501</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Peptidylprolyl isomerase]]		[[Category: Peptidylprolyl isomerase]]

OCA at 04:14, 27 July 2012

2012-07-27T04:14:35Z

←Older revision		Revision as of 04:14, 27 July 2012
Line 1:		Line 1:
	[[Image:1cwc.png\|left\|200px]]		[[Image:1cwc.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1cwc", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1cwc\| PDB=1cwc \| SCENE= }}		{{STRUCTURE_1cwc\| PDB=1cwc \| SCENE= }}

Line 16:		Line 10:

	==See Also==		==See Also==
-	*[[Cyclophilin]]	+	*[[Cyclophilin\|Cyclophilin]]

	==Reference==		==Reference==