1d2y - Revision history

OCA at 06:48, 7 February 2024

2024-02-07T06:48:33Z

←Older revision		Revision as of 06:48, 7 February 2024
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	<StructureSection load='1d2y' size='340' side='right'caption='[[1d2y]], [[Resolution\|resolution]] 2.06Å' scene=''>		<StructureSection load='1d2y' size='340' side='right'caption='[[1d2y]], [[Resolution\|resolution]] 2.06Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1d2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bpt4 Bpt4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D2Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1d2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D2Y FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.06Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; max-height: 3em;'>[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1qsq\|1qsq]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>GENE E ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~10665 BPT4])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [https://pdbe.org/1d2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [https://www.ebi.ac.uk/pdbsum/1d2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d2y ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [https://pdbe.org/1d2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [https://www.ebi.ac.uk/pdbsum/1d2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d2y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~LYS_BPT4 LYS_BPT4~~]~~] Helps~~ to ~~release~~ the mature ~~phage~~ particles ~~from~~ the cell ~~wall by breaking~~ down the peptidoglycan.	+	[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d2y ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d2y ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Using heavily methionine-substituted T4 lysozyme as an example, it is shown how the addition or deletion of a small number of methionines can simplify the location of selenium sites for use in MAD phasing. By comparing the X-ray data for a large number of singly substituted lysozymes, it is shown that the optimal amino acid to be substituted by methionine is leucine, followed, in order of preference, by phenylalanine, isoleucine and valine. The identification of leucine as the first choice agrees with the ranking suggested by the Dayhoff mutation probability, i.e. by the frequency of amino-acid substitutions in the sequences of related proteins. The ranking of the second and subsequent choices, however, differ significantly.
-
-	Use of differentially substituted selenomethionine proteins in X-ray structure determination.,Gassner NC, Matthews BW Acta Crystallogr D Biol Crystallogr. 1999 Dec;55(Pt 12):1967-70. PMID:10666571<ref>PMID:10666571</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1d2y" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 38:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bpt4~~]]	+	[[Category: Escherichia virus T4]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Lysozyme]]~~	+	[[Category: Gassner NC]]
-	[[Category: Gassner~~, N C~~]]	+	[[Category: Matthews BW]]
-	[[Category: Matthews~~, B W]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Methionine core mutant]]~~	+
-	~~[[Category: Protein engineering]]~~	+
-	~~[[Category: Protein folding]]~~	+
-	~~[[Category: T4 lysozyme~~]]	+

OCA at 14:58, 3 November 2021

2021-11-03T14:58:47Z

OCA at 10:19, 18 November 2020

2020-11-18T10:19:40Z

←Older revision		Revision as of 10:19, 18 November 2020
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	==N-TERMINAL DOMAIN CORE METHIONINE MUTATION==		==N-TERMINAL DOMAIN CORE METHIONINE MUTATION==
-	<StructureSection load='1d2y' size='340' side='right' caption='[[1d2y]], [[Resolution\|resolution]] 2.06Å' scene=''>	+	<StructureSection load='1d2y' size='340' side='right'caption='[[1d2y]], [[Resolution\|resolution]] 2.06Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1d2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Y OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1D2Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1d2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Y OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1D2Y FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1qsq\|1qsq]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1qsq\|1qsq]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [http://pdbe.org/1d2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [http://www.ebi.ac.uk/pdbsum/1d2y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1d2y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [http://pdbe.org/1d2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [http://www.ebi.ac.uk/pdbsum/1d2y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1d2y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 31:		Line 31:
	</div>		</div>
	<div class="pdbe-citations 1d2y" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1d2y" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 39:
	</StructureSection>		</StructureSection>
	[[Category: Bpt4]]		[[Category: Bpt4]]
		+	[[Category: Large Structures]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Gassner, N C]]		[[Category: Gassner, N C]]

OCA at 06:10, 31 January 2018

2018-01-31T06:10:09Z

←Older revision		Revision as of 06:10, 31 January 2018
Line 31:		Line 31:
	</div>		</div>
	<div class="pdbe-citations 1d2y" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1d2y" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:37, 6 December 2017

2017-12-06T08:37:51Z

←Older revision		Revision as of 08:37, 6 December 2017
Line 1:		Line 1:
		+
	==N-TERMINAL DOMAIN CORE METHIONINE MUTATION==		==N-TERMINAL DOMAIN CORE METHIONINE MUTATION==
	<StructureSection load='1d2y' size='340' side='right' caption='[[1d2y]], [[Resolution\|resolution]] 2.06Å' scene=''>		<StructureSection load='1d2y' size='340' side='right' caption='[[1d2y]], [[Resolution\|resolution]] 2.06Å' scene=''>
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	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [http://pdbe.org/1d2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [http://www.ebi.ac.uk/pdbsum/1d2y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [http://pdbe.org/1d2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [http://www.ebi.ac.uk/pdbsum/1d2y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1d2y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d2/1d2y_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d2/1d2y_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 22:18, 9 February 2016

2016-02-09T22:18:33Z

←Older revision		Revision as of 22:18, 9 February 2016
Line 19:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d2y ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 02:35, 11 September 2015

2015-09-11T02:35:09Z

←Older revision		Revision as of 02:35, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1d2y' size='340' side='right' caption='[[1d2y]], [[Resolution\|resolution]] 2.06Å' scene=''>		<StructureSection load='1d2y' size='340' side='right' caption='[[1d2y]], [[Resolution\|resolution]] 2.06Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1d2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacteria_phage_t4 Enterobacteria phage t4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1D2Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1d2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1D2Y FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1qsq\|1qsq]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1qsq\|1qsq]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 ~~Enterobacteria phage T4~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [http://www.ebi.ac.uk/pdbsum/1d2y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [http://pdbe.org/1d2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [http://www.ebi.ac.uk/pdbsum/1d2y PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 29:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1d2y" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Enterobacteria phage t4~~]]	+	[[Category: Bpt4]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Gassner, N C]]		[[Category: Gassner, N C]]

OCA at 09:54, 25 December 2014

2014-12-25T09:54:39Z

←Older revision		Revision as of 09:54, 25 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [http://www.ebi.ac.uk/pdbsum/1d2y PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [http://www.ebi.ac.uk/pdbsum/1d2y PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LYS_BPT4 LYS_BPT4]] Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 22:55, 22 December 2014

2014-12-22T22:55:21Z

←Older revision		Revision as of 22:55, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1d2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1D2Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[1d2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1D2Y FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1qsq\|1qsq]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1qsq\|1qsq]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [http://www.ebi.ac.uk/pdbsum/1d2y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [http://www.ebi.ac.uk/pdbsum/1d2y PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 36:
	[[Category: Enterobacteria phage t4]]		[[Category: Enterobacteria phage t4]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
-	[[Category: Gassner, N C.]]	+	[[Category: Gassner, N C]]
-	[[Category: Matthews, B W.]]	+	[[Category: Matthews, B W]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Methionine core mutant]]		[[Category: Methionine core mutant]]

OCA at 09:28, 27 August 2014

2014-08-27T09:28:15Z

←Older revision		Revision as of 09:28, 27 August 2014
Line 1:		Line 1:
-	[[~~Image:~~1d2y.~~png~~\|~~left~~\|200px]]	+	==N-TERMINAL DOMAIN CORE METHIONINE MUTATION==
		+	<StructureSection load='1d2y' size='340' side='right' caption='[[1d2y]], [[Resolution\|resolution]] 2.06Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1d2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1D2Y FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1qsq\|1qsq]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [http://www.ebi.ac.uk/pdbsum/1d2y PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d2/1d2y_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Using heavily methionine-substituted T4 lysozyme as an example, it is shown how the addition or deletion of a small number of methionines can simplify the location of selenium sites for use in MAD phasing. By comparing the X-ray data for a large number of singly substituted lysozymes, it is shown that the optimal amino acid to be substituted by methionine is leucine, followed, in order of preference, by phenylalanine, isoleucine and valine. The identification of leucine as the first choice agrees with the ranking suggested by the Dayhoff mutation probability, i.e. by the frequency of amino-acid substitutions in the sequences of related proteins. The ranking of the second and subsequent choices, however, differ significantly.

-	~~{{STRUCTURE_1d2y\| PDB=1d2y \| SCENE= }}~~	+	Use of differentially substituted selenomethionine proteins in X-ray structure determination.,Gassner NC, Matthews BW Acta Crystallogr D Biol Crystallogr. 1999 Dec;55(Pt 12):1967-70. PMID:10666571<ref>PMID:10666571</ref>

-	~~===N-TERMINAL DOMAIN CORE METHIONINE MUTATION===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10666571}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1d2y]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Y OCA].~~	+

	==See Also==		==See Also==
-	*[[~~Hen Egg-White (HEW)~~ Lysozyme\|~~Hen Egg-White (HEW)~~ Lysozyme]]	+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:010666571<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Enterobacteria phage t4]]		[[Category: Enterobacteria phage t4]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]

←Older revision		Revision as of 14:58, 3 November 2021
Line 3:		Line 3:
	<StructureSection load='1d2y' size='340' side='right'caption='[[1d2y]], [[Resolution\|resolution]] 2.06Å' scene=''>		<StructureSection load='1d2y' size='340' side='right'caption='[[1d2y]], [[Resolution\|resolution]] 2.06Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1d2y]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Y OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1D2Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1d2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D2Y FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1qsq\|1qsq]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1qsq\|1qsq]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [~~http~~://pdbe.org/1d2y PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1d2y PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1d2y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2y OCA], [https://pdbe.org/1d2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d2y RCSB], [https://www.ebi.ac.uk/pdbsum/1d2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d2y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/LYS_BPT4 LYS_BPT4]] Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.	+	[[https://www.uniprot.org/uniprot/LYS_BPT4 LYS_BPT4]] Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]