1dti - Revision history

OCA at 05:57, 9 August 2023

2023-08-09T05:57:52Z

←Older revision		Revision as of 05:57, 9 August 2023
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	<StructureSection load='1dti' size='340' side='right'caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='1dti' size='340' side='right'caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Phymc Phymc~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DTI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DTI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [https://pdbe.org/1dti PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [https://www.ebi.ac.uk/pdbsum/1dti PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dti ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [https://pdbe.org/1dti PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [https://www.ebi.ac.uk/pdbsum/1dti PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dti ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	+	[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Phymc~~]]	+	[[Category: Physeter catodon]]
-	[[Category: Liong~~, E C~~]]	+	[[Category: Liong EC]]
-	[[Category: Phillips~~, G N]]~~	+	[[Category: Phillips Jr GN]]
-	~~[[Category: Heme]]~~	+
-	~~[[Category: Muscle protein]]~~	+
-	~~[[Category: Oxygen storage-transport complex]]~~	+
-	~~[[Category: Oxygen transport~~]]	+

OCA at 15:02, 3 November 2021

2021-11-03T15:02:28Z

←Older revision		Revision as of 15:02, 3 November 2021
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	<StructureSection load='1dti' size='340' side='right'caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='1dti' size='340' side='right'caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Phycd Phycd~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DTI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Phymc Phymc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DTI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [https://pdbe.org/1dti PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [https://www.ebi.ac.uk/pdbsum/1dti PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dti ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [https://pdbe.org/1dti PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [https://www.ebi.ac.uk/pdbsum/1dti PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dti ProSAT]</span></td></tr>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Phycd~~]]	+	[[Category: Phymc]]
	[[Category: Liong, E C]]		[[Category: Liong, E C]]
	[[Category: Phillips, G N]]		[[Category: Phillips, G N]]

OCA at 09:31, 21 July 2021

2021-07-21T09:31:18Z

←Older revision		Revision as of 09:31, 21 July 2021
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	<StructureSection load='1dti' size='340' side='right'caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='1dti' size='340' side='right'caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Phycd Phycd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1DTI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Phycd Phycd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DTI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [~~http~~://pdbe.org/1dti PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1dti PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1dti ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [https://pdbe.org/1dti PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [https://www.ebi.ac.uk/pdbsum/1dti PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dti ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	+	[[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Myoglobin\|Myoglobin]]	+	*[[Myoglobin 3D structures\|Myoglobin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:13, 16 October 2019

2019-10-16T13:13:22Z

←Older revision		Revision as of 13:13, 16 October 2019
Line 1:		Line 1:

	==Recombinant sperm whale myoglobin h97d, d122n mutant (met)==		==Recombinant sperm whale myoglobin h97d, d122n mutant (met)==
-	<StructureSection load='1dti' size='340' side='right' caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>	+	<StructureSection load='1dti' size='340' side='right'caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phycd Phycd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DTI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phycd Phycd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DTI FirstGlance]. <br>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1dti" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1dti" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Myoglobin\|Myoglobin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Phycd]]		[[Category: Phycd]]
	[[Category: Liong, E C]]		[[Category: Liong, E C]]

OCA at 07:51, 13 December 2017

2017-12-13T07:51:22Z

←Older revision		Revision as of 07:51, 13 December 2017
Line 1:		Line 1:
		+
	==Recombinant sperm whale myoglobin h97d, d122n mutant (met)==		==Recombinant sperm whale myoglobin h97d, d122n mutant (met)==
	<StructureSection load='1dti' size='340' side='right' caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='1dti' size='340' side='right' caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phycd Phycd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DTI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phycd Phycd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DTI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [http://pdbe.org/1dti PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [http://www.ebi.ac.uk/pdbsum/1dti PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [http://pdbe.org/1dti PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [http://www.ebi.ac.uk/pdbsum/1dti PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1dti ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/1dti_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/1dti_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1dti" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1dti" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Myoglobin\|Myoglobin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 21:11, 7 February 2016

2016-02-07T21:11:14Z

←Older revision		Revision as of 21:11, 7 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dti ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:01, 10 September 2015

2015-09-10T05:01:16Z

←Older revision		Revision as of 05:01, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1dti' size='340' side='right' caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='1dti' size='340' side='right' caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Physeter_catodon Physeter catodon~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DTI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phycd Phycd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DTI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [http://www.ebi.ac.uk/pdbsum/1dti PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [http://pdbe.org/1dti PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [http://www.ebi.ac.uk/pdbsum/1dti PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1dti" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Physeter catodon~~]]	+	[[Category: Phycd]]
	[[Category: Liong, E C]]		[[Category: Liong, E C]]
	[[Category: Phillips, G N]]		[[Category: Phillips, G N]]

OCA at 18:17, 24 December 2014

2014-12-24T18:17:10Z

←Older revision		Revision as of 18:17, 24 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [http://www.ebi.ac.uk/pdbsum/1dti PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [http://www.ebi.ac.uk/pdbsum/1dti PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 19:40, 22 December 2014

2014-12-22T19:40:47Z

←Older revision		Revision as of 19:40, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DTI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DTI FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [http://www.ebi.ac.uk/pdbsum/1dti PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [http://www.ebi.ac.uk/pdbsum/1dti PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Physeter catodon]]		[[Category: Physeter catodon]]
-	[[Category: Liong, E C.]]	+	[[Category: Liong, E C]]
-	[[Category: Phillips, G N.]]	+	[[Category: Phillips, G N]]
	[[Category: Heme]]		[[Category: Heme]]
	[[Category: Muscle protein]]		[[Category: Muscle protein]]
	[[Category: Oxygen storage-transport complex]]		[[Category: Oxygen storage-transport complex]]
	[[Category: Oxygen transport]]		[[Category: Oxygen transport]]

OCA at 10:40, 10 September 2014

2014-09-10T10:40:52Z

←Older revision		Revision as of 10:40, 10 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1dti.~~png\|left~~\|200px]]	+	==Recombinant sperm whale myoglobin h97d, d122n mutant (met)==
		+	<StructureSection load='1dti' size='340' side='right' caption='[[1dti]], [[Resolution\|resolution]] 1.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1dti]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DTI FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dti OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dti RCSB], [http://www.ebi.ac.uk/pdbsum/1dti PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/1dti_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The ability of myoglobin to bind oxygen reversibly depends critically on retention of the heme prosthetic group. Globin side chains at the Leu(89)(F4), His(97)(FG3), Ile(99)(FG5), and Leu(104)(G5) positions on the proximal side of the heme pocket strongly influence heme affinity. The roles of these amino acids in preventing heme loss have been examined by determining high resolution structures of 14 different mutants at these positions using x-ray crystallography. Leu(89) and His(97) are important surface amino acids that interact either sterically or electrostatically with the edges of the porphyrin ring. Ile(99) and Leu(104) are located in the interior region of the proximal pocket beneath ring C of the heme prosthetic group. The apolar amino acids Leu(89), Ile(99), and Leu(104) "waterproof" the heme pocket by forming a barrier to solvent penetration, minimizing the size of the proximal cavity, and maintaining a hydrophobic environment. Substitutions with smaller or polar side chains at these positions result in exposure of the heme to solvent, the appearance of crystallographically defined water molecules in or near the proximal pocket, and large increases in the rate of hemin loss. Thus, the naturally occurring amino acid side chains at these positions serve to prevent hydration of the His(93)-Fe(III) bond and are highly conserved in all known myoglobins and hemoglobins.

-	~~{{STRUCTURE_1dti\| PDB=1dti \| SCENE= }}~~	+	Waterproofing the heme pocket. Role of proximal amino acid side chains in preventing hemin loss from myoglobin.,Liong EC, Dou Y, Scott EE, Olson JS, Phillips GN Jr J Biol Chem. 2001 Mar 23;276(12):9093-100. Epub 2000 Nov 17. PMID:11084036<ref>PMID:11084036</ref>

-	~~===Recombinant sperm whale myoglobin h97d~~, ~~d122n mutant (met)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11084036}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1dti]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Physeter_catodon Physeter catodon]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1DTI OCA].~~	+

	==See Also==		==See Also==
	*[[Myoglobin\|Myoglobin]]		*[[Myoglobin\|Myoglobin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:011084036<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Physeter catodon]]		[[Category: Physeter catodon]]
	[[Category: Liong, E C.]]		[[Category: Liong, E C.]]