1eq6 - Revision history

OCA at 07:06, 7 February 2024

2024-02-07T07:06:00Z

←Older revision		Revision as of 07:06, 7 February 2024
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	<StructureSection load='1eq6' size='340' side='right'caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1eq6' size='340' side='right'caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [https://pdbe.org/1eq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [https://www.ebi.ac.uk/pdbsum/1eq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eq6 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [https://pdbe.org/1eq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [https://www.ebi.ac.uk/pdbsum/1eq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eq6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MOG1_YEAST MOG1_YEAST]] Involved in the Ran-GTPase system for nuclear protein import and poly(A)+ mRNA export.<ref>PMID:9860978</ref> <ref>PMID:11509570</ref>	+	[https://www.uniprot.org/uniprot/MOG1_YEAST MOG1_YEAST] Involved in the Ran-GTPase system for nuclear protein import and poly(A)+ mRNA export.<ref>PMID:9860978</ref> <ref>PMID:11509570</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eq6 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eq6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The 1.9 A resolution X-ray crystal structure of Ran-binding protein Mog1p shows that it has a unique fold based on a six-stranded antiparallel beta-sheet backed on both sides by an extensive alpha-helix. The topology of some elements of Mog1p secondary structure resemble a portion of nuclear transport factor 2 (NTF2), but the hydrophobic cavity and surrounding negatively charged residues that are important in the NTF2-RanGDP interaction are not conserved in Mog1p. In addition to binding RanGTP, Mog1p forms a 1:1 complex with RanGDP and so binds Ran independent of its nucleotide state. Mog1p and NTF2 compete for binding to RanGDP indicating that their binding sites on RanGDP are sufficiently close to prevent both proteins binding simultaneously. Although there may be some overlap between the Mog1p and NTF2 binding sites on RanGDP, these sites are not identical. Sequence analysis of Mog1p homologues from Schizosaccharomyces pombe, human, and Caenorhabditis elegans in the context of the Mog1p crystal structure indicates the presence of a cluster of highly conserved surface residues consistent with an interaction site for Ran.
-
-	1.9 A resolution crystal structure of the Saccharomyces cerevisiae Ran-binding protein Mog1p.,Stewart M, Baker RP J Mol Biol. 2000 May 26;299(1):213-23. PMID:10860733<ref>PMID:10860733</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1eq6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Baker, R P~~]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: ~~Stewart, M~~]]	+	[[Category: Baker RP]]
-	[[Category: ~~Alpha-beta]]~~	+	[[Category: Stewart M]]
-	~~[[Category: Protein transport~~]]	+

OCA at 06:32, 11 August 2021

2021-08-11T06:32:32Z

←Older revision		Revision as of 06:32, 11 August 2021
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	<StructureSection load='1eq6' size='340' side='right'caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1eq6' size='340' side='right'caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [~~http~~://pdbe.org/1eq6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1eq6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1eq6 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [https://pdbe.org/1eq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [https://www.ebi.ac.uk/pdbsum/1eq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eq6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MOG1_YEAST MOG1_YEAST]] Involved in the Ran-GTPase system for nuclear protein import and poly(A)+ mRNA export.<ref>PMID:9860978</ref> <ref>PMID:11509570</ref>	+	[[https://www.uniprot.org/uniprot/MOG1_YEAST MOG1_YEAST]] Involved in the Ran-GTPase system for nuclear protein import and poly(A)+ mRNA export.<ref>PMID:9860978</ref> <ref>PMID:11509570</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 09:40, 6 November 2019

2019-11-06T09:40:39Z

←Older revision		Revision as of 09:40, 6 November 2019
Line 1:		Line 1:

	==1.9 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE RAN-BINDING PROTEIN MOG1P==		==1.9 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE RAN-BINDING PROTEIN MOG1P==
-	<StructureSection load='1eq6' size='340' side='right' caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='1eq6' size='340' side='right'caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
		+	[[Category: Large Structures]]
	[[Category: Baker, R P]]		[[Category: Baker, R P]]
	[[Category: Stewart, M]]		[[Category: Stewart, M]]
	[[Category: Alpha-beta]]		[[Category: Alpha-beta]]
	[[Category: Protein transport]]		[[Category: Protein transport]]

OCA at 06:14, 31 January 2018

2018-01-31T06:14:35Z

←Older revision		Revision as of 06:14, 31 January 2018
Line 3:		Line 3:
	<StructureSection load='1eq6' size='340' side='right' caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1eq6' size='340' side='right' caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [http://pdbe.org/1eq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1eq6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1eq6 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [http://pdbe.org/1eq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1eq6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1eq6 ProSAT]</span></td></tr>
	</table>		</table>
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/1eq6_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/1eq6_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 31:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 18824]]
	[[Category: Baker, R P]]		[[Category: Baker, R P]]
	[[Category: Stewart, M]]		[[Category: Stewart, M]]
	[[Category: Alpha-beta]]		[[Category: Alpha-beta]]
	[[Category: Protein transport]]		[[Category: Protein transport]]

OCA at 03:58, 6 September 2017

2017-09-06T03:58:27Z

←Older revision		Revision as of 03:58, 6 September 2017
Line 1:		Line 1:
		+
	==1.9 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE RAN-BINDING PROTEIN MOG1P==		==1.9 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE RAN-BINDING PROTEIN MOG1P==
	<StructureSection load='1eq6' size='340' side='right' caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1eq6' size='340' side='right' caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [http://pdbe.org/1eq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1eq6 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [http://pdbe.org/1eq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1eq6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1eq6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eq6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 30:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
	[[Category: Baker, R P]]		[[Category: Baker, R P]]
	[[Category: Stewart, M]]		[[Category: Stewart, M]]
	[[Category: Alpha-beta]]		[[Category: Alpha-beta]]
	[[Category: Protein transport]]		[[Category: Protein transport]]

OCA at 11:01, 11 September 2015

2015-09-11T11:01:22Z

←Older revision		Revision as of 11:01, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1eq6' size='340' side='right' caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1eq6' size='340' side='right' caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1eq6 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [http://pdbe.org/1eq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1eq6 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1eq6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Saccharomyces cerevisiae~~]]	+	[[Category: Atcc 18824]]
	[[Category: Baker, R P]]		[[Category: Baker, R P]]
	[[Category: Stewart, M]]		[[Category: Stewart, M]]
	[[Category: Alpha-beta]]		[[Category: Alpha-beta]]
	[[Category: Protein transport]]		[[Category: Protein transport]]

OCA at 15:33, 25 December 2014

2014-12-25T15:33:56Z

←Older revision		Revision as of 15:33, 25 December 2014
Line 5:		Line 5:
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1eq6 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1eq6 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MOG1_YEAST MOG1_YEAST]] Involved in the Ran-GTPase system for nuclear protein import and poly(A)+ mRNA export.<ref>PMID:9860978</ref> <ref>PMID:11509570</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 19:00, 22 December 2014

2014-12-22T19:00:29Z

←Older revision		Revision as of 19:00, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1eq6 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1eq6 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Baker, R P.]]	+	[[Category: Baker, R P]]
-	[[Category: Stewart, M.]]	+	[[Category: Stewart, M]]
	[[Category: Alpha-beta]]		[[Category: Alpha-beta]]
	[[Category: Protein transport]]		[[Category: Protein transport]]

OCA at 11:27, 24 September 2014

2014-09-24T11:27:07Z

←Older revision		Revision as of 11:27, 24 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1eq6.~~png\|left~~\|200px]]	+	==1.9 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE RAN-BINDING PROTEIN MOG1P==
		+	<StructureSection load='1eq6' size='340' side='right' caption='[[1eq6]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1eq6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQ6 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1eq6 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/1eq6_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The 1.9 A resolution X-ray crystal structure of Ran-binding protein Mog1p shows that it has a unique fold based on a six-stranded antiparallel beta-sheet backed on both sides by an extensive alpha-helix. The topology of some elements of Mog1p secondary structure resemble a portion of nuclear transport factor 2 (NTF2), but the hydrophobic cavity and surrounding negatively charged residues that are important in the NTF2-RanGDP interaction are not conserved in Mog1p. In addition to binding RanGTP, Mog1p forms a 1:1 complex with RanGDP and so binds Ran independent of its nucleotide state. Mog1p and NTF2 compete for binding to RanGDP indicating that their binding sites on RanGDP are sufficiently close to prevent both proteins binding simultaneously. Although there may be some overlap between the Mog1p and NTF2 binding sites on RanGDP, these sites are not identical. Sequence analysis of Mog1p homologues from Schizosaccharomyces pombe, human, and Caenorhabditis elegans in the context of the Mog1p crystal structure indicates the presence of a cluster of highly conserved surface residues consistent with an interaction site for Ran.

-	~~{{STRUCTURE_1eq6\| PDB=1eq6 \| SCENE= }}~~	+	1.9 A resolution crystal structure of the Saccharomyces cerevisiae Ran-binding protein Mog1p.,Stewart M, Baker RP J Mol Biol. 2000 May 26;299(1):213-23. PMID:10860733<ref>PMID:10860733</ref>

-	~~===1.9 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE RAN-BINDING PROTEIN MOG1P===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~==About this Structure==~~	+	<references/>
-	~~[[1eq6]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1EQ6 OCA].~~	+	__TOC__
-		+	</StructureSection>
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:010860733<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Baker, R P.]]		[[Category: Baker, R P.]]

OCA: Protected "1eq6" [edit=sysop:move=sysop]

2012-11-08T14:38:11Z

Protected "1eq6" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:38, 8 November 2012