1ghg - Revision history

OCA at 23:31, 27 December 2023

2023-12-27T23:31:54Z

←Older revision		Revision as of 23:31, 27 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ghg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GHG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ghg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GHG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3FG:(2S)-AMINO(3,5-DIHYDROXYPHENYL)ETHANOIC+ACID'>3FG</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=OMY:(BETAR)-3-CHLORO-BETA-HYDROXY-L-TYROSINE'>OMY</scene>, <scene name='pdbligand=OMZ:(BETAR)-3-CHLORO-BETA-HYDROXY-D-TYROSINE'>OMZ</scene>, <scene name='pdbligand=PRD_000206:VANCOMYCIN+AGLYCON'>PRD_000206</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 0.98Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3FG:(2S)-AMINO(3,5-DIHYDROXYPHENYL)ETHANOIC+ACID'>3FG</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=OMY:(BETAR)-3-CHLORO-BETA-HYDROXY-L-TYROSINE'>OMY</scene>, <scene name='pdbligand=OMZ:(BETAR)-3-CHLORO-BETA-HYDROXY-D-TYROSINE'>OMZ</scene>, <scene name='pdbligand=PRD_000206:VANCOMYCIN+AGLYCON'>PRD_000206</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ghg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ghg OCA], [https://pdbe.org/1ghg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ghg RCSB], [https://www.ebi.ac.uk/pdbsum/1ghg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ghg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ghg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ghg OCA], [https://pdbe.org/1ghg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ghg RCSB], [https://www.ebi.ac.uk/pdbsum/1ghg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ghg ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:00, 11 January 2023

2023-01-11T08:00:33Z

←Older revision		Revision as of 08:00, 11 January 2023
Line 3:		Line 3:
	<StructureSection load='1ghg' size='340' side='right'caption='[[1ghg]], [[Resolution\|resolution]] 0.98Å' scene=''>		<StructureSection load='1ghg' size='340' side='right'caption='[[1ghg]], [[Resolution\|resolution]] 0.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ghg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GHG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ghg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GHG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=~~ACY~~:~~ACETIC~~+ACID'>~~ACY~~</scene>, <scene name='pdbligand=~~DMS~~:~~DIMETHYL~~+~~SULFOXIDE~~'>~~DMS~~</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3FG:(2S)-AMINO(3,5-DIHYDROXYPHENYL)ETHANOIC+ACID'>3FG</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=OMY:(BETAR)-3-CHLORO-BETA-HYDROXY-L-TYROSINE'>OMY</scene>, <scene name='pdbligand=OMZ:(BETAR)-3-CHLORO-BETA-HYDROXY-D-TYROSINE'>OMZ</scene>, <scene name='pdbligand=PRD_000206:VANCOMYCIN+AGLYCON'>PRD_000206</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~3FG~~:~~(2S)-AMINO(3,5-DIHYDROXYPHENYL)ETHANOIC~~+~~ACID~~'>~~3FG~~</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=OMY:(BETAR)-3-CHLORO-BETA-HYDROXY-L-TYROSINE'>OMY</scene>, <scene name='pdbligand=OMZ:(BETAR)-3-CHLORO-BETA-HYDROXY-D-TYROSINE'>OMZ</scene><~~/td></tr>~~	+
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;~~'>~~[[1aa5\|1aa5]], [[1c0q\|1c0q]], [[1c0r\|1c0r]], [[1fvm\|1fvm]], [[1gac\|1gac]], [[1pn3\|1pn3]], [[1pnv\|1pnv]], [[1qd8\|1qd8]], [[1rrv\|1rrv]], [[1sho\|1sho]]~~</~~div~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ghg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ghg OCA], [https://pdbe.org/1ghg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ghg RCSB], [https://www.ebi.ac.uk/pdbsum/1ghg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ghg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ghg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ghg OCA], [https://pdbe.org/1ghg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ghg RCSB], [https://www.ebi.ac.uk/pdbsum/1ghg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ghg ProSAT]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Amycolatopsis orientalis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Axelsen~~, P H~~]]	+	[[Category: Axelsen PH]]
-	[[Category: Kaplan, J]]	+	[[Category: Kaplan J]]
-	[[Category: Korty~~, B D~~]]	+	[[Category: Korty BD]]
-	[[Category: Loll~~, P J]]~~	+	[[Category: Loll PJ]]
-	~~[[Category: Aglycon]]~~	+
-	~~[[Category: Antibiotic]]~~	+
-	~~[[Category: Glycopeptide]]~~	+
-	~~[[Category: Vancomycin~~]]	+

OCA at 11:01, 31 March 2021

2021-03-31T11:01:32Z

←Older revision		Revision as of 11:01, 31 March 2021
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	<StructureSection load='1ghg' size='340' side='right'caption='[[1ghg]], [[Resolution\|resolution]] 0.98Å' scene=''>		<StructureSection load='1ghg' size='340' side='right'caption='[[1ghg]], [[Resolution\|resolution]] 0.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ghg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1GHG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ghg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GHG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=3FG:(2S)-AMINO(3,5-DIHYDROXYPHENYL)ETHANOIC+ACID'>3FG</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=OMY:(BETAR)-3-CHLORO-BETA-HYDROXY-L-TYROSINE'>OMY</scene>, <scene name='pdbligand=OMZ:(BETAR)-3-CHLORO-BETA-HYDROXY-D-TYROSINE'>OMZ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=3FG:(2S)-AMINO(3,5-DIHYDROXYPHENYL)ETHANOIC+ACID'>3FG</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=OMY:(BETAR)-3-CHLORO-BETA-HYDROXY-L-TYROSINE'>OMY</scene>, <scene name='pdbligand=OMZ:(BETAR)-3-CHLORO-BETA-HYDROXY-D-TYROSINE'>OMZ</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aa5\|1aa5]], [[1c0q\|1c0q]], [[1c0r\|1c0r]], [[1fvm\|1fvm]], [[1gac\|1gac]], [[1pn3\|1pn3]], [[1pnv\|1pnv]], [[1qd8\|1qd8]], [[1rrv\|1rrv]], [[1sho\|1sho]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1aa5\|1aa5]], [[1c0q\|1c0q]], [[1c0r\|1c0r]], [[1fvm\|1fvm]], [[1gac\|1gac]], [[1pn3\|1pn3]], [[1pnv\|1pnv]], [[1qd8\|1qd8]], [[1rrv\|1rrv]], [[1sho\|1sho]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ghg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ghg OCA], [~~http~~://pdbe.org/1ghg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ghg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ghg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ghg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ghg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ghg OCA], [https://pdbe.org/1ghg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ghg RCSB], [https://www.ebi.ac.uk/pdbsum/1ghg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ghg ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:49, 26 June 2019

2019-06-26T08:49:45Z

←Older revision		Revision as of 08:49, 26 June 2019
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF VANCOMYCIN AGLYCON==		==CRYSTAL STRUCTURE OF VANCOMYCIN AGLYCON==
-	<StructureSection load='1ghg' size='340' side='right' caption='[[1ghg]], [[Resolution\|resolution]] 0.98Å' scene=''>	+	<StructureSection load='1ghg' size='340' side='right'caption='[[1ghg]], [[Resolution\|resolution]] 0.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ghg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GHG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ghg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GHG FirstGlance]. <br>
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Axelsen, P H]]		[[Category: Axelsen, P H]]
	[[Category: Kaplan, J]]		[[Category: Kaplan, J]]

OCA at 04:43, 21 September 2017

2017-09-21T04:43:31Z

←Older revision		Revision as of 04:43, 21 September 2017
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF VANCOMYCIN AGLYCON==		==CRYSTAL STRUCTURE OF VANCOMYCIN AGLYCON==
	<StructureSection load='1ghg' size='340' side='right' caption='[[1ghg]], [[Resolution\|resolution]] 0.98Å' scene=''>		<StructureSection load='1ghg' size='340' side='right' caption='[[1ghg]], [[Resolution\|resolution]] 0.98Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=3FG:(2S)-AMINO(3,5-DIHYDROXYPHENYL)ETHANOIC+ACID'>3FG</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=OMY:(BETAR)-3-CHLORO-BETA-HYDROXY-L-TYROSINE'>OMY</scene>, <scene name='pdbligand=OMZ:(BETAR)-3-CHLORO-BETA-HYDROXY-D-TYROSINE'>OMZ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=3FG:(2S)-AMINO(3,5-DIHYDROXYPHENYL)ETHANOIC+ACID'>3FG</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=OMY:(BETAR)-3-CHLORO-BETA-HYDROXY-L-TYROSINE'>OMY</scene>, <scene name='pdbligand=OMZ:(BETAR)-3-CHLORO-BETA-HYDROXY-D-TYROSINE'>OMZ</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aa5\|1aa5]], [[1c0q\|1c0q]], [[1c0r\|1c0r]], [[1fvm\|1fvm]], [[1gac\|1gac]], [[1pn3\|1pn3]], [[1pnv\|1pnv]], [[1qd8\|1qd8]], [[1rrv\|1rrv]], [[1sho\|1sho]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aa5\|1aa5]], [[1c0q\|1c0q]], [[1c0r\|1c0r]], [[1fvm\|1fvm]], [[1gac\|1gac]], [[1pn3\|1pn3]], [[1pnv\|1pnv]], [[1qd8\|1qd8]], [[1rrv\|1rrv]], [[1sho\|1sho]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ghg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ghg OCA], [http://pdbe.org/1ghg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ghg RCSB], [http://www.ebi.ac.uk/pdbsum/1ghg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ghg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ghg OCA], [http://pdbe.org/1ghg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ghg RCSB], [http://www.ebi.ac.uk/pdbsum/1ghg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ghg ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:52, 11 September 2015

2015-09-11T08:52:07Z

←Older revision		Revision as of 08:52, 11 September 2015
Line 6:		Line 6:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=3FG:(2S)-AMINO(3,5-DIHYDROXYPHENYL)ETHANOIC+ACID'>3FG</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=OMY:(BETAR)-3-CHLORO-BETA-HYDROXY-L-TYROSINE'>OMY</scene>, <scene name='pdbligand=OMZ:(BETAR)-3-CHLORO-BETA-HYDROXY-D-TYROSINE'>OMZ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=3FG:(2S)-AMINO(3,5-DIHYDROXYPHENYL)ETHANOIC+ACID'>3FG</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=OMY:(BETAR)-3-CHLORO-BETA-HYDROXY-L-TYROSINE'>OMY</scene>, <scene name='pdbligand=OMZ:(BETAR)-3-CHLORO-BETA-HYDROXY-D-TYROSINE'>OMZ</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aa5\|1aa5]], [[1c0q\|1c0q]], [[1c0r\|1c0r]], [[1fvm\|1fvm]], [[1gac\|1gac]], [[1pn3\|1pn3]], [[1pnv\|1pnv]], [[1qd8\|1qd8]], [[1rrv\|1rrv]], [[1sho\|1sho]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aa5\|1aa5]], [[1c0q\|1c0q]], [[1c0r\|1c0r]], [[1fvm\|1fvm]], [[1gac\|1gac]], [[1pn3\|1pn3]], [[1pnv\|1pnv]], [[1qd8\|1qd8]], [[1rrv\|1rrv]], [[1sho\|1sho]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ghg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ghg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ghg RCSB], [http://www.ebi.ac.uk/pdbsum/1ghg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ghg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ghg OCA], [http://pdbe.org/1ghg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ghg RCSB], [http://www.ebi.ac.uk/pdbsum/1ghg PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ghg" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:49, 22 December 2014

2014-12-22T06:49:10Z

←Older revision		Revision as of 06:49, 22 December 2014
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-	~~{{STRUCTURE_1ghg~~\| ~~PDB~~=1ghg \| ~~SCENE~~= }}	+	==CRYSTAL STRUCTURE OF VANCOMYCIN AGLYCON==
-	===~~CRYSTAL STRUCTURE OF VANCOMYCIN AGLYCON~~===	+	<StructureSection load='1ghg' size='340' side='right' caption='[[1ghg]], [[Resolution\|resolution]] 0.98Å' scene=''>
-	~~{{ABSTRACT_PUBMED_11356118}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ghg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GHG FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=3FG:(2S)-AMINO(3,5-DIHYDROXYPHENYL)ETHANOIC+ACID'>3FG</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=OMY:(BETAR)-3-CHLORO-BETA-HYDROXY-L-TYROSINE'>OMY</scene>, <scene name='pdbligand=OMZ:(BETAR)-3-CHLORO-BETA-HYDROXY-D-TYROSINE'>OMZ</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aa5\|1aa5]], [[1c0q\|1c0q]], [[1c0r\|1c0r]], [[1fvm\|1fvm]], [[1gac\|1gac]], [[1pn3\|1pn3]], [[1pnv\|1pnv]], [[1qd8\|1qd8]], [[1rrv\|1rrv]], [[1sho\|1sho]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ghg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ghg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ghg RCSB], [http://www.ebi.ac.uk/pdbsum/1ghg PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The sugar residues of the glycopeptide antibiotic vancomycin contribute to the cooperativity of ligand binding, thereby increasing ligand affinity and enhancing antimicrobial activity. To assess the structural basis for these effects, we determined a 0.98 A X-ray crystal structure of the vancomycin aglycon and compared it to structures of several intact vancomycin:ligand complexes. The crystal structure reveals that the aglycon binds acetate anions and forms back-to-back dimeric complexes in a manner similar to that of intact vancomycin. However, the four independent copies of the aglycon in each asymmetric unit of the crystal exhibit a high degree of conformational heterogeneity. These results suggest that the sugar residues, in addition to enlarging and strengthening the dimer interface, provide steric constraints that limit the vancomycin molecule to a relatively small number of productive conformations.

-	~~==About this Structure==~~	+	The role of sugar residues in molecular recognition by vancomycin.,Kaplan J, Korty BD, Axelsen PH, Loll PJ J Med Chem. 2001 May 24;44(11):1837-40. PMID:11356118<ref>PMID:11356118</ref>
-	~~[[1ghg]] is a 4 chain structure~~. ~~Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann.ac.il~~/~~oca-bin/ocashort?id=1GHG OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:011356118</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
-	[[Category: Axelsen, P H.]]	+	== References ==
-	[[Category: Kaplan, J.]]	+	<references/>
-	[[Category: Korty, B D.]]	+	__TOC__
-	[[Category: Loll, P J.]]	+	</StructureSection>
		+	[[Category: Axelsen, P H]]
		+	[[Category: Kaplan, J]]
		+	[[Category: Korty, B D]]
		+	[[Category: Loll, P J]]
	[[Category: Aglycon]]		[[Category: Aglycon]]
	[[Category: Antibiotic]]		[[Category: Antibiotic]]
	[[Category: Glycopeptide]]		[[Category: Glycopeptide]]
	[[Category: Vancomycin]]		[[Category: Vancomycin]]

OCA at 11:00, 16 April 2014

2014-04-16T11:00:32Z

←Older revision		Revision as of 11:00, 16 April 2014
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-	[[Image:1ghg.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_1ghg", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1ghg\| PDB=1ghg \| SCENE= }}		{{STRUCTURE_1ghg\| PDB=1ghg \| SCENE= }}
-
	===CRYSTAL STRUCTURE OF VANCOMYCIN AGLYCON===		===CRYSTAL STRUCTURE OF VANCOMYCIN AGLYCON===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11356118}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11356118 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_11356118}}		{{ABSTRACT_PUBMED_11356118}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:011356118</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011356118</ref><references group="xtra"/><references/>
	[[Category: Axelsen, P H.]]		[[Category: Axelsen, P H.]]
	[[Category: Kaplan, J.]]		[[Category: Kaplan, J.]]

OCA: Protected "1ghg" [edit=sysop:move=sysop]

2011-07-27T05:20:38Z

Protected "1ghg" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:20, 27 July 2011

OCA at 05:20, 27 July 2011

2011-07-27T05:20:36Z

←Older revision		Revision as of 05:20, 27 July 2011
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-	{{Seed}}
	[[Image:1ghg.png\|left\|200px]]		[[Image:1ghg.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHG OCA].	+	[[1ghg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHG OCA].

	==Reference==		==Reference==
-	~~The role of sugar residues in molecular recognition by vancomycin., Kaplan J, Korty BD, Axelsen PH, Loll PJ, J Med Chem. 2001 May 24;44(11):1837-40.~~ PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~11356118 11356118]~~	+	<ref group="xtra">PMID:011356118</ref><references group="xtra"/>
	[[Category: Axelsen, P H.]]		[[Category: Axelsen, P H.]]
	[[Category: Kaplan, J.]]		[[Category: Kaplan, J.]]
Line 29:		Line 28:
	[[Category: Loll, P J.]]		[[Category: Loll, P J.]]
	[[Category: Aglycon]]		[[Category: Aglycon]]
-	[[Category: ~~Glycopeptide antibiotic~~]]	+	[[Category: Antibiotic]]
-		+	[[Category: Glycopeptide]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Jul 1 05~~:~~17:30 2008''~~	+	[[Category: Vancomycin]]