1gqx - Revision history

OCA at 11:27, 28 July 2021

2021-07-28T11:27:24Z

←Older revision		Revision as of 11:27, 28 July 2021
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	<StructureSection load='1gqx' size='340' side='right'caption='[[1gqx]]' scene=''>		<StructureSection load='1gqx' size='340' side='right'caption='[[1gqx]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1GQX FirstGlance]. <br>	+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GQX FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1gqx FirstGlance], [~~http~~://www.ebi.ac.uk/pdbsum/1gqx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1gqx ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gqx FirstGlance], [https://www.ebi.ac.uk/pdbsum/1gqx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gqx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:23, 23 October 2019

2019-10-23T08:23:14Z

←Older revision		Revision as of 08:23, 23 October 2019
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	==MODELLED STRUCTURE OF 2,4-DICHLOROPHENOXYACETIC ACID/ ALPHA- KETOGLUTARATE DIOXYGENASE==		==MODELLED STRUCTURE OF 2,4-DICHLOROPHENOXYACETIC ACID/ ALPHA- KETOGLUTARATE DIOXYGENASE==
-	<StructureSection load='1gqx' size='340' side='right' caption='[[1gqx]]' scene=''>	+	<StructureSection load='1gqx' size='340' side='right'caption='[[1gqx]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQX FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQX FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Theoretical Model]]		[[Category: Theoretical Model]]
		+	[[Category: Large Structures]]
	[[Category: Baldwin, J E]]		[[Category: Baldwin, J E]]
	[[Category: Burzlaff, N I]]		[[Category: Burzlaff, N I]]

OCA at 06:13, 3 January 2018

2018-01-03T06:13:09Z

←Older revision		Revision as of 06:13, 3 January 2018
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQX FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQX FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gqx FirstGlance], [http://www.ebi.ac.uk/pdbsum/1gqx PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gqx FirstGlance], [http://www.ebi.ac.uk/pdbsum/1gqx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gqx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:59, 11 February 2016

2016-02-11T08:59:00Z

←Older revision		Revision as of 08:59, 11 February 2016
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		+	{{Theoretical_model}}
		+
	==MODELLED STRUCTURE OF 2,4-DICHLOROPHENOXYACETIC ACID/ ALPHA- KETOGLUTARATE DIOXYGENASE==		==MODELLED STRUCTURE OF 2,4-DICHLOROPHENOXYACETIC ACID/ ALPHA- KETOGLUTARATE DIOXYGENASE==
	<StructureSection load='1gqx' size='340' side='right' caption='[[1gqx]]' scene=''>		<StructureSection load='1gqx' size='340' side='right' caption='[[1gqx]]' scene=''>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Theoretical Model]]
	[[Category: Baldwin, J E]]		[[Category: Baldwin, J E]]
	[[Category: Burzlaff, N I]]		[[Category: Burzlaff, N I]]

OCA at 01:12, 12 September 2015

2015-09-12T01:12:46Z

←Older revision		Revision as of 01:12, 12 September 2015
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1gqx" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 23:20, 22 December 2014

2014-12-22T23:20:41Z

←Older revision		Revision as of 23:20, 22 December 2014
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQX FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQX FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gqx FirstGlance], [http://www.ebi.ac.uk/pdbsum/1gqx PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gqx FirstGlance], [http://www.ebi.ac.uk/pdbsum/1gqx PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 13:03, 28 September 2014

2014-09-28T13:03:41Z

←Older revision		Revision as of 13:03, 28 September 2014
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-	~~{{Theoretical_model}}~~	+	==MODELLED STRUCTURE OF 2,4-DICHLOROPHENOXYACETIC ACID/ ALPHA- KETOGLUTARATE DIOXYGENASE==
		+	<StructureSection load='1gqx' size='340' side='right' caption='[[1gqx]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQX FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gqx FirstGlance], [http://www.ebi.ac.uk/pdbsum/1gqx PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Taurine/alpha-ketoglutarate dioxygenase (TauD), a non-heme Fe(II) oxygenase, catalyses the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrent with the conversion of alpha-ketoglutarate (alphaKG) to succinate and CO(2). The enzyme allows Escherichia coli to use taurine, widely available in the environment, as an alternative sulfur source. Here we describe the X-ray crystal structure of TauD complexed to Fe(II) and both substrates, alphaKG and taurine. The tertiary structure and fold of TauD are similar to those observed in other enzymes from the broad family of Fe(II)/alphaKG-dependent oxygenases, with closest structural similarity to clavaminate synthase. Using the TauD coordinates, a model was determined for the closely related enzyme 2,4-dichlorophenoxyacetate/alphaKG dioxygenase (TfdA), supporting predictions derived from site-directed mutagenesis and other studies of that biodegradative protein. The TauD structure and TfdA model define the metal ligands and the positions of nearby aromatic residues that undergo post-translational modifications involving self-hydroxylation reactions. The substrate binding residues of TauD were identified and those of TfdA predicted. These results, along with sequence alignment information, reveal how TauD selects a tetrahedral substrate anion in preference to the planar carboxylate selected by TfdA, providing insight into the mechanism of enzyme catalysis.

-	~~[[Image~~:~~1gqx~~.~~png\|left\|200px]]~~	+	X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates.,Elkins JM, Ryle MJ, Clifton IJ, Dunning Hotopp JC, Lloyd JS, Burzlaff NI, Baldwin JE, Hausinger RP, Roach PL Biochemistry. 2002 Apr 23;41(16):5185-92. PMID:11955067<ref>PMID:11955067</ref>

-	~~{{STRUCTURE_1gqx\| PDB=1gqx \| SCENE= }}~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~===MODELLED STRUCTURE OF 2,4-DICHLOROPHENOXYACETIC ACID~~/ ~~ALPHA- KETOGLUTARATE DIOXYGENASE===~~	+	== References ==
-		+	<references/>
-	~~{{ABSTRACT_PUBMED_11955067}}~~	+	__TOC__
-		+	</StructureSection>
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011955067<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Baldwin, J E]]		[[Category: Baldwin, J E]]
	[[Category: Burzlaff, N I]]		[[Category: Burzlaff, N I]]

OCA: Protected "1gqx" [edit=sysop:move=sysop]

2012-10-21T08:40:26Z

Protected "1gqx" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:40, 21 October 2012

OCA at 08:40, 21 October 2012

2012-10-21T08:40:23Z

←Older revision		Revision as of 08:40, 21 October 2012
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	{{Theoretical_model}}		{{Theoretical_model}}
-	~~{{Seed}}~~	+
	[[Image:1gqx.png\|left\|200px]]		[[Image:1gqx.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1gqx", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1gqx\| PDB=1gqx \| SCENE= }}		{{STRUCTURE_1gqx\| PDB=1gqx \| SCENE= }}

	===MODELLED STRUCTURE OF 2,4-DICHLOROPHENOXYACETIC ACID/ ALPHA- KETOGLUTARATE DIOXYGENASE===		===MODELLED STRUCTURE OF 2,4-DICHLOROPHENOXYACETIC ACID/ ALPHA- KETOGLUTARATE DIOXYGENASE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11955067}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11955067 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_11955067}}		{{ABSTRACT_PUBMED_11955067}}
-
-	==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQX OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11955067~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011955067</ref><references group="xtra"/>
	[[Category: Baldwin, J E]]		[[Category: Baldwin, J E]]
	[[Category: Burzlaff, N I]]		[[Category: Burzlaff, N I]]
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	[[Category: Roach, P L]]		[[Category: Roach, P L]]
	[[Category: Ryle, M J]]		[[Category: Ryle, M J]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 06:35:42 2010''

OCA at 03:35, 8 April 2010

2010-04-08T03:35:42Z

←Older revision		Revision as of 03:35, 8 April 2010
Line 1:		Line 1:
-	~~'''Theoretical Model'''~~	+	{{Theoretical_model}}
		+	{{Seed}}
		+	[[Image:1gqx.png\|left\|200px]]

-	The ~~entry 1GQX~~ is ~~a Theoretical Model titled 'MODELLED STRUCTURE OF 2~~,4-~~DICHLOROPHENOXYACETIC ACID/ ALPHA~~-~~KETOGLUTARATE DIOXYGENASE'.~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_1gqx", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_1gqx\| PDB=1gqx \| SCENE= }}

-	~~[[Category:Theoretical Model]]~~	+	===MODELLED STRUCTURE OF 2,4-DICHLOROPHENOXYACETIC ACID/ ALPHA- KETOGLUTARATE DIOXYGENASE===


-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 30 09~~:49:~~53 2008~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_11955067}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 11955067 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_11955067}}
		+
		+	==About this Structure==
		+	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQX OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:11955067</ref><references group="xtra"/>
		+	[[Category: Baldwin, J E]]
		+	[[Category: Burzlaff, N I]]
		+	[[Category: Clifton, I J]]
		+	[[Category: Dunning-Hotopp, J C]]
		+	[[Category: Elkins, J M]]
		+	[[Category: Hausinger, R P]]
		+	[[Category: Lloyd, J S]]
		+	[[Category: Roach, P L]]
		+	[[Category: Ryle, M J]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 06:35:42 2010''