1h1n - Revision history

OCA at 11:26, 27 March 2024

2024-03-27T11:26:51Z

←Older revision		Revision as of 11:26, 27 March 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H1N FirstGlance]. <br>		<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H1N FirstGlance]. <br>
-	</td></tr><tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"~~><span class~~=~~'plainlinks'~~>[~~https://en.wikipedia.org/wiki/Cellulase Cellulase~~]~~, with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.~~1.~~4 3.2.1.4] </span>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.12Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1n OCA], [https://pdbe.org/1h1n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h1n RCSB], [https://www.ebi.ac.uk/pdbsum/1h1n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h1n ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1n OCA], [https://pdbe.org/1h1n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h1n RCSB], [https://www.ebi.ac.uk/pdbsum/1h1n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h1n ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8TG26_THEAU Q8TG26_THEAU]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h1n ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h1n ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The crystal structure of the major endoglucanase from the thermophilic fungus Thermoascus aurantiacus was determined by single isomorphous replacement at 1.12A resolution. The full sequence supports the classification of the protein in a subgroup of glycoside hydrolase family 5 for which no structural data are available yet. The active site shows eight critical residues, strictly conserved within family 5. In addition, aromatic residues that line the substrate-binding cleft and that are possibly involved in substrate-binding are identified. A number of residues seem to be conserved among members of the subtype, including a disulphide bridge between Cys212 and Cys249.
-
-	Atomic resolution structure of the major endoglucanase from Thermoascus aurantiacus.,Van Petegem F, Vandenberghe I, Bhat MK, Van Beeumen J Biochem Biophys Res Commun. 2002 Aug 9;296(1):161-6. PMID:12147244<ref>PMID:12147244</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1h1n" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Glucanase 3D structures\|Glucanase 3D structures]]		*[[Glucanase 3D structures\|Glucanase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Cellulase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Thermoascus aurantiacus]]		[[Category: Thermoascus aurantiacus]]
-	[[Category: ~~Beeumen, J Van~~]]	+	[[Category: Bhat MK]]
-	[[Category: ~~Bhat, M K~~]]	+	[[Category: Van Beeumen J]]
-	[[Category: Petegem, F ~~Van~~]]	+	[[Category: Van Petegem F]]
-	[[Category: Vandenberghe, I]]	+	[[Category: Vandenberghe I]]
-	~~[[Category: Endoglucanase]]~~	+
-	~~[[Category: Family 5]]~~	+
-	~~[[Category: Glycosyl hydrolase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Subtype]]~~	+
-	~~[[Category: Thermophile]]~~	+
-	~~[[Category: Thermophilic~~]]	+

OCA at 05:48, 28 April 2021

2021-04-28T05:48:15Z

←Older revision		Revision as of 05:48, 28 April 2021
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	<StructureSection load='1h1n' size='340' side='right'caption='[[1h1n]], [[Resolution\|resolution]] 1.12Å' scene=''>		<StructureSection load='1h1n' size='340' side='right'caption='[[1h1n]], [[Resolution\|resolution]] 1.12Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1H1N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H1N FirstGlance]. <br>
-	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1h1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1n OCA], [~~http~~://pdbe.org/1h1n PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1h1n RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1h1n PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1h1n ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1n OCA], [https://pdbe.org/1h1n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h1n RCSB], [https://www.ebi.ac.uk/pdbsum/1h1n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h1n ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 06:42, 24 July 2019

2019-07-24T06:42:25Z

←Older revision		Revision as of 06:42, 24 July 2019
Line 28:		Line 28:

	==See Also==		==See Also==
-	*[[Glucanase\|Glucanase]]	+	*[[Glucanase 3D structures\|Glucanase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:02, 23 May 2019

2019-05-23T07:02:53Z

←Older revision		Revision as of 07:02, 23 May 2019
Line 1:		Line 1:

	==Atomic resolution structure of the major endoglucanase from Thermoascus aurantiacus==		==Atomic resolution structure of the major endoglucanase from Thermoascus aurantiacus==
-	<StructureSection load='1h1n' size='340' side='right' caption='[[1h1n]], [[Resolution\|resolution]] 1.12Å' scene=''>	+	<StructureSection load='1h1n' size='340' side='right'caption='[[1h1n]], [[Resolution\|resolution]] 1.12Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H1N FirstGlance]. <br>		<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H1N FirstGlance]. <br>
Line 11:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h1/1h1n_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h1/1h1n_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 26:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 1h1n" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1h1n" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Glucanase\|Glucanase]]
	== References ==		== References ==
	<references/>		<references/>
Line 31:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Cellulase]]		[[Category: Cellulase]]
		+	[[Category: Large Structures]]
	[[Category: Thermoascus aurantiacus]]		[[Category: Thermoascus aurantiacus]]
	[[Category: Beeumen, J Van]]		[[Category: Beeumen, J Van]]

OCA at 11:43, 6 November 2017

2017-11-06T11:43:30Z

←Older revision		Revision as of 11:43, 6 November 2017
Line 26:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 1h1n" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1h1n" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Glucanase\|Glucanase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:55, 3 August 2017

2017-08-03T08:55:30Z

←Older revision		Revision as of 08:55, 3 August 2017
Line 1:		Line 1:
-	==~~ATOMIC RESOLUTION STRUCTURE OF THE MAJOR ENDOGLUCANASE FROM THERMOASCUS AURANTIACUS~~==	+
		+	==Atomic resolution structure of the major endoglucanase from Thermoascus aurantiacus==
	<StructureSection load='1h1n' size='340' side='right' caption='[[1h1n]], [[Resolution\|resolution]] 1.12Å' scene=''>		<StructureSection load='1h1n' size='340' side='right' caption='[[1h1n]], [[Resolution\|resolution]] 1.12Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H1N FirstGlance]. <br>		<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H1N FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1n OCA], [http://pdbe.org/1h1n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h1n RCSB], [http://www.ebi.ac.uk/pdbsum/1h1n PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1n OCA], [http://pdbe.org/1h1n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h1n RCSB], [http://www.ebi.ac.uk/pdbsum/1h1n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1h1n ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 23:43, 9 February 2016

2016-02-09T23:43:45Z

←Older revision		Revision as of 23:43, 9 February 2016
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h1n ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 03:14, 11 September 2015

2015-09-11T03:14:24Z

←Older revision		Revision as of 03:14, 11 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H1N FirstGlance]. <br>		<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H1N FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h1n RCSB], [http://www.ebi.ac.uk/pdbsum/1h1n PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1n OCA], [http://pdbe.org/1h1n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h1n RCSB], [http://www.ebi.ac.uk/pdbsum/1h1n PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1h1n" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 23:38, 22 December 2014

2014-12-22T23:38:31Z

←Older revision		Revision as of 23:38, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H1N FirstGlance]. <br>		<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H1N FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h1n RCSB], [http://www.ebi.ac.uk/pdbsum/1h1n PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h1n RCSB], [http://www.ebi.ac.uk/pdbsum/1h1n PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Cellulase]]		[[Category: Cellulase]]
	[[Category: Thermoascus aurantiacus]]		[[Category: Thermoascus aurantiacus]]
-	[[Category: Beeumen, J Van.]]	+	[[Category: Beeumen, J Van]]
-	[[Category: Bhat, M K.]]	+	[[Category: Bhat, M K]]
-	[[Category: Petegem, F Van.]]	+	[[Category: Petegem, F Van]]
-	[[Category: Vandenberghe, I.]]	+	[[Category: Vandenberghe, I]]
	[[Category: Endoglucanase]]		[[Category: Endoglucanase]]
	[[Category: Family 5]]		[[Category: Family 5]]

OCA at 13:21, 28 September 2014

2014-09-28T13:21:30Z

←Older revision		Revision as of 13:21, 28 September 2014
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-	[[~~Image~~:1h1n.~~png\|left~~\|200px]]	+	==ATOMIC RESOLUTION STRUCTURE OF THE MAJOR ENDOGLUCANASE FROM THERMOASCUS AURANTIACUS==
		+	<StructureSection load='1h1n' size='340' side='right' caption='[[1h1n]], [[Resolution\|resolution]] 1.12Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1h1n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H1N FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h1n RCSB], [http://www.ebi.ac.uk/pdbsum/1h1n PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h1/1h1n_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structure of the major endoglucanase from the thermophilic fungus Thermoascus aurantiacus was determined by single isomorphous replacement at 1.12A resolution. The full sequence supports the classification of the protein in a subgroup of glycoside hydrolase family 5 for which no structural data are available yet. The active site shows eight critical residues, strictly conserved within family 5. In addition, aromatic residues that line the substrate-binding cleft and that are possibly involved in substrate-binding are identified. A number of residues seem to be conserved among members of the subtype, including a disulphide bridge between Cys212 and Cys249.

-	~~{{STRUCTURE_1h1n\| PDB=1h1n \| SCENE= }}~~	+	Atomic resolution structure of the major endoglucanase from Thermoascus aurantiacus.,Van Petegem F, Vandenberghe I, Bhat MK, Van Beeumen J Biochem Biophys Res Commun. 2002 Aug 9;296(1):161-6. PMID:12147244<ref>PMID:12147244</ref>

-	~~===ATOMIC RESOLUTION STRUCTURE OF THE MAJOR ENDOGLUCANASE FROM THERMOASCUS AURANTIACUS===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12147244}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1h1n]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1H1N OCA].~~	+

	==See Also==		==See Also==
	*[[Glucanase\|Glucanase]]		*[[Glucanase\|Glucanase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:012147244<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Cellulase]]		[[Category: Cellulase]]
	[[Category: Thermoascus aurantiacus]]		[[Category: Thermoascus aurantiacus]]