1igu - Revision history

OCA at 08:33, 16 August 2023

2023-08-16T08:33:30Z

←Older revision		Revision as of 08:33, 16 August 2023
Line 3:		Line 3:
	<StructureSection load='1igu' size='340' side='right'caption='[[1igu]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1igu' size='340' side='right'caption='[[1igu]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1igu]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1IGU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1igu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IGU FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[1igq\|1igq]]</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">korb ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=562 "Bacillus coli" Migula 1895])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1igu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igu OCA], [https://pdbe.org/1igu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1igu RCSB], [https://www.ebi.ac.uk/pdbsum/1igu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1igu ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1igu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igu OCA], [~~http~~://pdbe.org/1igu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1igu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1igu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1igu ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/KORB2_ECOLX KORB2_ECOLX]] In conjunction with KorA, inhibits the transcription of the kilA, trfA and korAB operons. Is also involved in the negative control of the kilB operon.	+	[https://www.uniprot.org/uniprot/KORB2_ECOLX KORB2_ECOLX] In conjunction with KorA, inhibits the transcription of the kilA, trfA and korAB operons. Is also involved in the negative control of the kilB operon.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Delbruck, H]]	+	[[Category: Delbruck H]]
-	[[Category: Heinemann, U]]	+	[[Category: Heinemann U]]
-	~~[[Category: Dimerization domain]]~~	+
-	~~[[Category: Sh3 domain]]~~	+
-	~~[[Category: Transcription~~]]	+

OCA at 10:38, 18 November 2020

2020-11-18T10:38:42Z

←Older revision		Revision as of 10:38, 18 November 2020
Line 1:		Line 1:

	==C-terminal Domain of the Transcriptional Repressor Protein KorB==		==C-terminal Domain of the Transcriptional Repressor Protein KorB==
-	<StructureSection load='1igu' size='340' side='right' caption='[[1igu]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='1igu' size='340' side='right'caption='[[1igu]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1igu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1IGU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1igu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1IGU FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1igq\|1igq]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1igq\|1igq]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">korb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">korb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1igu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igu OCA], [http://pdbe.org/1igu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1igu RCSB], [http://www.ebi.ac.uk/pdbsum/1igu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1igu ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1igu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igu OCA], [http://pdbe.org/1igu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1igu RCSB], [http://www.ebi.ac.uk/pdbsum/1igu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1igu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Delbruck, H]]		[[Category: Delbruck, H]]
	[[Category: Heinemann, U]]		[[Category: Heinemann, U]]

OCA at 09:16, 10 January 2018

2018-01-10T09:16:07Z

←Older revision		Revision as of 09:16, 10 January 2018
Line 1:		Line 1:
		+
	==C-terminal Domain of the Transcriptional Repressor Protein KorB==		==C-terminal Domain of the Transcriptional Repressor Protein KorB==
	<StructureSection load='1igu' size='340' side='right' caption='[[1igu]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1igu' size='340' side='right' caption='[[1igu]], [[Resolution\|resolution]] 2.20Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1igq\|1igq]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1igq\|1igq]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">korb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">korb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1igu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igu OCA], [http://pdbe.org/1igu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1igu RCSB], [http://www.ebi.ac.uk/pdbsum/1igu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1igu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igu OCA], [http://pdbe.org/1igu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1igu RCSB], [http://www.ebi.ac.uk/pdbsum/1igu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1igu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/1igu_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/1igu_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 23:38, 8 February 2016

2016-02-08T23:38:54Z

←Older revision		Revision as of 23:38, 8 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1igu ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 16:28, 10 September 2015

2015-09-10T16:28:29Z

←Older revision		Revision as of 16:28, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1igu' size='340' side='right' caption='[[1igu]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1igu' size='340' side='right' caption='[[1igu]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1igu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IGU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1igu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IGU FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1igq\|1igq]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1igq\|1igq]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">korb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">korb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1igu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1igu RCSB], [http://www.ebi.ac.uk/pdbsum/1igu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1igu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igu OCA], [http://pdbe.org/1igu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1igu RCSB], [http://www.ebi.ac.uk/pdbsum/1igu PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~KORB2_ECOLI KORB2_ECOLI~~]] In conjunction with KorA, inhibits the transcription of the kilA, trfA and korAB operons. Is also involved in the negative control of the kilB operon.	+	[[http://www.uniprot.org/uniprot/KORB2_ECOLX KORB2_ECOLX]] In conjunction with KorA, inhibits the transcription of the kilA, trfA and korAB operons. Is also involved in the negative control of the kilB operon.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1igu" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Delbruck, H]]		[[Category: Delbruck, H]]
	[[Category: Heinemann, U]]		[[Category: Heinemann, U]]

OCA at 02:56, 25 December 2014

2014-12-25T02:56:26Z

←Older revision		Revision as of 02:56, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1igu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IGU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1igu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IGU FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1igq\|1igq]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1igq\|1igq]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">korb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">korb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1igu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1igu RCSB], [http://www.ebi.ac.uk/pdbsum/1igu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1igu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1igu RCSB], [http://www.ebi.ac.uk/pdbsum/1igu PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/KORB2_ECOLI KORB2_ECOLI]] In conjunction with KorA, inhibits the transcription of the kilA, trfA and korAB operons. Is also involved in the negative control of the kilB operon.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Delbruck, H.]]	+	[[Category: Delbruck, H]]
-	[[Category: Heinemann, U.]]	+	[[Category: Heinemann, U]]
	[[Category: Dimerization domain]]		[[Category: Dimerization domain]]
	[[Category: Sh3 domain]]		[[Category: Sh3 domain]]
	[[Category: Transcription]]		[[Category: Transcription]]

OCA at 08:43, 28 September 2014

2014-09-28T08:43:45Z

←Older revision		Revision as of 08:43, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1igu.~~png~~\|~~left~~\|200px]]	+	==C-terminal Domain of the Transcriptional Repressor Protein KorB==
		+	<StructureSection load='1igu' size='340' side='right' caption='[[1igu]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1igu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IGU FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1igq\|1igq]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">korb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1igu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1igu RCSB], [http://www.ebi.ac.uk/pdbsum/1igu PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/1igu_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	KorB is a regulatory protein encoded by the conjugative plasmid RP4 and a member of the ParB family of bacterial partitioning proteins. The protein regulates the expression of plasmid genes whose products are involved in replication, transfer, and stable inheritance of RP4 by binding to palindromic 13-bp DNA sequences (5'-TTTAGC(G/C)GCTAAA-3') present 12 times in the 60-kb plasmid. Here we report the crystal structure of KorB-C, the C-terminal domain of KorB comprising residues 297-358. The structure of KorB-C was solved in two crystal forms. Quite unexpectedly, we find that KorB-C shows a fold closely resembling the Src homology 3 (SH3) domain, a fold well known from proteins involved in eukaryotic signal transduction. From the arrangement of molecules in the asymmetric unit, it is concluded that two molecules form a functionally relevant dimer. The detailed analysis of the dimer interface and a chemical cross-linking study suggest that the C-terminal domain is responsible for stabilizing the dimeric form of KorB in solution to facilitate binding to the palindromic operator sequence. The KorB-C crystal structure extends the range of protein-protein interactions known to be promoted by SH3 and SH3-like domains.

-	~~{{STRUCTURE_1igu\| PDB=1igu \| SCENE= }}~~	+	An Src homology 3-like domain is responsible for dimerization of the repressor protein KorB encoded by the promiscuous IncP plasmid RP4.,Delbruck H, Ziegelin G, Lanka E, Heinemann U J Biol Chem. 2002 Feb 8;277(6):4191-8. Epub 2001 Nov 15. PMID:11711548<ref>PMID:11711548</ref>

-	~~===C-terminal Domain~~ of the ~~Transcriptional Repressor Protein KorB===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11711548}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1igu]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011711548<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Delbruck, H.]]		[[Category: Delbruck, H.]]

OCA: Protected "1igu" [edit=sysop:move=sysop]

2012-11-28T14:50:35Z

Protected "1igu" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:50, 28 November 2012

OCA at 14:50, 28 November 2012

2012-11-28T14:50:31Z

←Older revision		Revision as of 14:50, 28 November 2012
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-	{{Seed}}
	[[Image:1igu.png\|left\|200px]]		[[Image:1igu.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1igu\| PDB=1igu \| SCENE= }}		{{STRUCTURE_1igu\| PDB=1igu \| SCENE= }}

	===C-terminal Domain of the Transcriptional Repressor Protein KorB===		===C-terminal Domain of the Transcriptional Repressor Protein KorB===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11711548}}, adds the Publication Abstract to the page
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	{{ABSTRACT_PUBMED_11711548}}		{{ABSTRACT_PUBMED_11711548}}

	==About this Structure==		==About this Structure==
-	~~1IGU~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA].	+	[[1igu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11711548~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011711548</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Delbruck, H.]]		[[Category: Delbruck, H.]]
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	[[Category: Dimerization domain]]		[[Category: Dimerization domain]]
	[[Category: Sh3 domain]]		[[Category: Sh3 domain]]
-		+	[[Category: Transcription]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 04:29:07 2009''~~	+

OCA at 02:29, 17 February 2009

2009-02-17T02:29:09Z

←Older revision		Revision as of 02:29, 17 February 2009
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	==About this Structure==		==About this Structure==
-	1IGU is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA].	+	1IGU is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGU OCA].

	==Reference==		==Reference==
-	An Src homology 3-like domain is responsible for dimerization of the repressor protein KorB encoded by the promiscuous IncP plasmid RP4., Delbruck H, Ziegelin G, Lanka E, Heinemann U, J Biol Chem. 2002 Feb 8;277(6):4191-8. Epub 2001 Nov 15. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/11711548 11711548]~~	+	<ref group="xtra">PMID:11711548</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Single protein]]
	[[Category: Delbruck, H.]]		[[Category: Delbruck, H.]]
	[[Category: Heinemann, U.]]		[[Category: Heinemann, U.]]
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	[[Category: Sh3 domain]]		[[Category: Sh3 domain]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 1 12~~:08:~~30 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:29:07 2009''