1ite - Revision history

OCA at 11:05, 4 August 2021

2021-08-04T11:05:24Z

←Older revision		Revision as of 11:05, 4 August 2021
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	<StructureSection load='1ite' size='340' side='right'caption='[[1ite]]' scene=''>		<StructureSection load='1ite' size='340' side='right'caption='[[1ite]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ITE FirstGlance]. <br>	+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ITE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ite FirstGlance], [~~http~~://www.ebi.ac.uk/pdbsum/1ite PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ite ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ite FirstGlance], [https://www.ebi.ac.uk/pdbsum/1ite PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ite ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:29, 30 October 2019

2019-10-30T10:29:43Z

←Older revision		Revision as of 10:29, 30 October 2019
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	==A MODEL OF THE COMPLEX BETWEEN INTERLEUKIN-4 AND ITS RECEPTORS==		==A MODEL OF THE COMPLEX BETWEEN INTERLEUKIN-4 AND ITS RECEPTORS==
-	<StructureSection load='1ite' size='340' side='right' caption='[[1ite]]' scene=''>	+	<StructureSection load='1ite' size='340' side='right'caption='[[1ite]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ITE FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ITE FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Theoretical Model]]		[[Category: Theoretical Model]]
		+	[[Category: Large Structures]]
	[[Category: Gustchina, A E]]		[[Category: Gustchina, A E]]
	[[Category: Schalk-Hihi, C]]		[[Category: Schalk-Hihi, C]]
	[[Category: Wlodawer, A]]		[[Category: Wlodawer, A]]
	[[Category: Zdanov, A S]]		[[Category: Zdanov, A S]]

OCA at 09:12, 17 January 2018

2018-01-17T09:12:55Z

←Older revision		Revision as of 09:12, 17 January 2018
Line 5:		Line 5:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ITE FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ITE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ite FirstGlance], [http://www.ebi.ac.uk/pdbsum/1ite PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ite FirstGlance], [http://www.ebi.ac.uk/pdbsum/1ite PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ite ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:05, 11 February 2016

2016-02-11T09:05:59Z

←Older revision		Revision as of 09:05, 11 February 2016
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		+	{{Theoretical_model}}
		+
	==A MODEL OF THE COMPLEX BETWEEN INTERLEUKIN-4 AND ITS RECEPTORS==		==A MODEL OF THE COMPLEX BETWEEN INTERLEUKIN-4 AND ITS RECEPTORS==
	<StructureSection load='1ite' size='340' side='right' caption='[[1ite]]' scene=''>		<StructureSection load='1ite' size='340' side='right' caption='[[1ite]]' scene=''>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Theoretical Model]]
	[[Category: Gustchina, A E]]		[[Category: Gustchina, A E]]
	[[Category: Schalk-Hihi, C]]		[[Category: Schalk-Hihi, C]]
	[[Category: Wlodawer, A]]		[[Category: Wlodawer, A]]
	[[Category: Zdanov, A S]]		[[Category: Zdanov, A S]]

OCA at 09:41, 10 September 2015

2015-09-10T09:41:43Z

←Older revision		Revision as of 09:41, 10 September 2015
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ite" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:44, 18 December 2014

2014-12-18T12:44:22Z

←Older revision		Revision as of 12:44, 18 December 2014
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-	~~{{Theoretical_model}}~~	+	==A MODEL OF THE COMPLEX BETWEEN INTERLEUKIN-4 AND ITS RECEPTORS==
		+	<StructureSection load='1ite' size='340' side='right' caption='[[1ite]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ITE FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ite FirstGlance], [http://www.ebi.ac.uk/pdbsum/1ite PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A three-dimensional model of interleukin-4 (IL-4) bound to one molecule each of the high- and low-affinity receptors (IL-4R and IL-2R gamma) was built, using the crystal structure of the complex of human growth hormone (HGH) with its receptor (HGHR) as a starting model. The modeling of IL-4 with its receptors was based on the conservation of the sequences and on the predicted structural organization for cytokine receptors, and assuming that the binding mode of the ligands would be similar. Analysis of the interface between IL-4 and both receptor molecules was carried out to reveal which residues are important for complex formation. The modeling procedures showed that there were no major problems in maintaining a reasonable fit of IL-4 with the two receptor molecules, in a manner analogous to the complex of HGH-HGHR. Many of the residues that appear by modeling to be important for binding between IL-4 and the receptors have been previously implicated in that role by different methods. A striking motif of aromatic and positively charged residues on the surface of the C-terminal domains of the receptors is highly conserved in the structure of HGH-HGHR and in the models of IL-4 complexed with its receptors.

-	~~{{STRUCTURE_1ite\| PDB=1ite \| SCENE= }}~~	+	A model of the complex between interleukin-4 and its receptors.,Gustchina A, Zdanov A, Schalk-Hihi C, Wlodawer A Proteins. 1995 Feb;21(2):140-8. PMID:7777489<ref>PMID:7777489</ref>
-	~~===~~A ~~MODEL OF THE COMPLEX BETWEEN INTERLEUKIN~~-4 ~~AND ITS RECEPTORS===~~	+
-	~~{{ABSTRACT_PUBMED_7777489}}~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:007777489</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Gustchina, A E]]		[[Category: Gustchina, A E]]
	[[Category: Schalk-Hihi, C]]		[[Category: Schalk-Hihi, C]]
	[[Category: Wlodawer, A]]		[[Category: Wlodawer, A]]
	[[Category: Zdanov, A S]]		[[Category: Zdanov, A S]]

OCA at 07:12, 25 March 2013

2013-03-25T07:12:08Z

←Older revision		Revision as of 07:12, 25 March 2013
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	{{Theoretical_model}}		{{Theoretical_model}}
-
-	[[Image:1ite.png\|left\|200px]]

	{{STRUCTURE_1ite\| PDB=1ite \| SCENE= }}		{{STRUCTURE_1ite\| PDB=1ite \| SCENE= }}
-
	===A MODEL OF THE COMPLEX BETWEEN INTERLEUKIN-4 AND ITS RECEPTORS===		===A MODEL OF THE COMPLEX BETWEEN INTERLEUKIN-4 AND ITS RECEPTORS===
-
	{{ABSTRACT_PUBMED_7777489}}		{{ABSTRACT_PUBMED_7777489}}

	==Reference==		==Reference==
-	<ref group="xtra">PMID:007777489</ref><references group="xtra"/>	+	<ref group="xtra">PMID:007777489</ref><references group="xtra"/><references/>
	[[Category: Gustchina, A E]]		[[Category: Gustchina, A E]]
	[[Category: Schalk-Hihi, C]]		[[Category: Schalk-Hihi, C]]
	[[Category: Wlodawer, A]]		[[Category: Wlodawer, A]]
	[[Category: Zdanov, A S]]		[[Category: Zdanov, A S]]

OCA: Protected "1ite" [edit=sysop:move=sysop]

2012-10-21T09:59:07Z

Protected "1ite" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:59, 21 October 2012

OCA at 09:59, 21 October 2012

2012-10-21T09:59:05Z

←Older revision		Revision as of 09:59, 21 October 2012
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	{{Theoretical_model}}		{{Theoretical_model}}
-	~~{{Seed}}~~	+
	[[Image:1ite.png\|left\|200px]]		[[Image:1ite.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1ite", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1ite\| PDB=1ite \| SCENE= }}		{{STRUCTURE_1ite\| PDB=1ite \| SCENE= }}

	===A MODEL OF THE COMPLEX BETWEEN INTERLEUKIN-4 AND ITS RECEPTORS===		===A MODEL OF THE COMPLEX BETWEEN INTERLEUKIN-4 AND ITS RECEPTORS===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_7777489}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 7777489 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_7777489}}		{{ABSTRACT_PUBMED_7777489}}
-
-	==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ITE OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~7777489~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:007777489</ref><references group="xtra"/>
	[[Category: Gustchina, A E]]		[[Category: Gustchina, A E]]
	[[Category: Schalk-Hihi, C]]		[[Category: Schalk-Hihi, C]]
	[[Category: Wlodawer, A]]		[[Category: Wlodawer, A]]
	[[Category: Zdanov, A S]]		[[Category: Zdanov, A S]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 09:20:10 2010''

OCA at 06:20, 8 April 2010

2010-04-08T06:20:10Z

←Older revision		Revision as of 06:20, 8 April 2010
Line 1:		Line 1:
-	~~'''Theoretical Model'''~~	+	{{Theoretical_model}}
		+	{{Seed}}
		+	[[Image:1ite.png\|left\|200px]]

-	The ~~entry 1ITE~~ is ~~a Theoretical Model titled 'A MODEL OF THE COMPLEX BETWEEN INTERLEUKIN-4 AND ITS RECEPTORS'~~.	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_1ite", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_1ite\| PDB=1ite \| SCENE= }}

-	~~[[Category:Theoretical Model]]~~	+	===A MODEL OF THE COMPLEX BETWEEN INTERLEUKIN-4 AND ITS RECEPTORS===


-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 30~~ 09~~:50~~:20 ~~2008~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_7777489}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 7777489 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_7777489}}
		+
		+	==About this Structure==
		+	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ITE OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:7777489</ref><references group="xtra"/>
		+	[[Category: Gustchina, A E]]
		+	[[Category: Schalk-Hihi, C]]
		+	[[Category: Wlodawer, A]]
		+	[[Category: Zdanov, A S]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 09:20:10 2010''