1ix2 - Revision history

OCA at 23:38, 27 December 2023

2023-12-27T23:38:30Z

←Older revision		Revision as of 23:38, 27 December 2023
Line 3:		Line 3:
	<StructureSection load='1ix2' size='340' side='right'caption='[[1ix2]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='1ix2' size='340' side='right'caption='[[1ix2]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ix2]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1IX2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ix2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IX2 FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.55Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[1lyq\|1lyq]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>plasmid pRJ1004 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~562~~ "~~Bacillus coli~~" ~~Migula 1895])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix2 OCA], [https://pdbe.org/1ix2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ix2 RCSB], [https://www.ebi.ac.uk/pdbsum/1ix2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ix2 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix2 OCA], [~~http~~://pdbe.org/1ix2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ix2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ix2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ix2 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/PCOC_ECOLX PCOC_ECOLX]] Required for the copper-inducible expression of copper resistance.	+	[https://www.uniprot.org/uniprot/PCOC_ECOLX PCOC_ECOLX] Required for the copper-inducible expression of copper resistance.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Demeler, B]]	+	[[Category: Demeler B]]
-	[[Category: Finney~~, L A~~]]	+	[[Category: Finney LA]]
-	[[Category: ~~Halloran, T V.O~~]]	+	[[Category: Huffman DL]]
-	[[Category: ~~Huffman, D L~~]]	+	[[Category: O'Halloran TV]]
-	[[Category: Rosenzweig~~, A C~~]]	+	[[Category: Rosenzweig AC]]
-	[[Category: Wernimont~~, A K]]~~	+	[[Category: Wernimont AK]]
-	~~[[Category: Beta barrel]]~~	+
-	~~[[Category: Metal binding protein]]~~	+
-	~~[[Category: Polymethionine cluster~~]]	+

OCA at 07:25, 25 November 2020

2020-11-25T07:25:51Z

←Older revision		Revision as of 07:25, 25 November 2020
Line 1:		Line 1:

	==Crystal Structure of Selenomethionine PcoC, a Copper Resistance Protein from Escherichia coli==		==Crystal Structure of Selenomethionine PcoC, a Copper Resistance Protein from Escherichia coli==
-	<StructureSection load='1ix2' size='340' side='right' caption='[[1ix2]], [[Resolution\|resolution]] 1.55Å' scene=''>	+	<StructureSection load='1ix2' size='340' side='right'caption='[[1ix2]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ix2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1IX2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ix2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1IX2 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lyq\|1lyq]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1lyq\|1lyq]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">plasmid pRJ1004 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">plasmid pRJ1004 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix2 OCA], [http://pdbe.org/1ix2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ix2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ix2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ix2 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix2 OCA], [http://pdbe.org/1ix2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ix2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ix2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ix2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Demeler, B]]		[[Category: Demeler, B]]
	[[Category: Finney, L A]]		[[Category: Finney, L A]]

OCA at 09:07, 17 January 2018

2018-01-17T09:07:32Z

←Older revision		Revision as of 09:07, 17 January 2018
Line 1:		Line 1:
		+
	==Crystal Structure of Selenomethionine PcoC, a Copper Resistance Protein from Escherichia coli==		==Crystal Structure of Selenomethionine PcoC, a Copper Resistance Protein from Escherichia coli==
	<StructureSection load='1ix2' size='340' side='right' caption='[[1ix2]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='1ix2' size='340' side='right' caption='[[1ix2]], [[Resolution\|resolution]] 1.55Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lyq\|1lyq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lyq\|1lyq]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">plasmid pRJ1004 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">plasmid pRJ1004 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix2 OCA], [http://pdbe.org/1ix2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ix2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ix2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix2 OCA], [http://pdbe.org/1ix2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ix2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ix2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ix2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/1ix2_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/1ix2_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 13:34, 8 February 2016

2016-02-08T13:34:07Z

←Older revision		Revision as of 13:34, 8 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ix2 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:04, 10 September 2015

2015-09-10T12:04:01Z

←Older revision		Revision as of 12:04, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1ix2' size='340' side='right' caption='[[1ix2]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='1ix2' size='340' side='right' caption='[[1ix2]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ix2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IX2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ix2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IX2 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lyq\|1lyq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lyq\|1lyq]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">plasmid pRJ1004 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">plasmid pRJ1004 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ix2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ix2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix2 OCA], [http://pdbe.org/1ix2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ix2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ix2 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~PCOC_ECOLI PCOC_ECOLI~~]] Required for the copper-inducible expression of copper resistance.	+	[[http://www.uniprot.org/uniprot/PCOC_ECOLX PCOC_ECOLX]] Required for the copper-inducible expression of copper resistance.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ix2" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Demeler, B]]		[[Category: Demeler, B]]
	[[Category: Finney, L A]]		[[Category: Finney, L A]]

OCA at 23:41, 24 December 2014

2014-12-24T23:41:42Z

←Older revision		Revision as of 23:41, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ix2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IX2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ix2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IX2 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lyq\|1lyq]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lyq\|1lyq]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">plasmid pRJ1004 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">plasmid pRJ1004 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ix2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ix2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ix2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ix2 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PCOC_ECOLI PCOC_ECOLI]] Required for the copper-inducible expression of copper resistance.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Demeler, B.]]	+	[[Category: Demeler, B]]
-	[[Category: Finney, L A.]]	+	[[Category: Finney, L A]]
-	[[Category: Halloran, T V.O.]]	+	[[Category: Halloran, T V.O]]
-	[[Category: Huffman, D L.]]	+	[[Category: Huffman, D L]]
-	[[Category: Rosenzweig, A C.]]	+	[[Category: Rosenzweig, A C]]
-	[[Category: Wernimont, A K.]]	+	[[Category: Wernimont, A K]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]
	[[Category: Polymethionine cluster]]		[[Category: Polymethionine cluster]]

OCA at 10:28, 28 September 2014

2014-09-28T10:28:10Z

←Older revision		Revision as of 10:28, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1ix2.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of Selenomethionine PcoC, a Copper Resistance Protein from Escherichia coli==
		+	<StructureSection load='1ix2' size='340' side='right' caption='[[1ix2]], [[Resolution\|resolution]] 1.55Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ix2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IX2 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lyq\|1lyq]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">plasmid pRJ1004 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ix2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ix2 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/1ix2_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	PcoC is a soluble periplasmic protein encoded by the plasmid-born pco copper resistance operon of Escherichia coli. Like PcoA, a multicopper oxidase encoded in the same locus and its chromosomal homolog CueO, PcoC contains unusual methionine rich sequences. Although essential for copper resistance, the functions of PcoC, PcoA, and their conserved methionine-rich sequences are not known. Similar methionine motifs observed in eukaryotic copper transporters have been proposed to bind copper, but there are no precedents for such metal binding sites in structurally characterized proteins. The high-resolution structures of apo PcoC, determined for both the native and selenomethionine-containing proteins, reveal a seven-stranded beta barrel with the methionines unexpectedly housed on a solvent-exposed loop. Several potential metal-binding sites can be discerned by comparing the structures to spectroscopic data reported for copper-loaded PcoC. In the native structure, the methionine loop interacts with the same loop on a second molecule in the asymmetric unit. In the selenomethionine structure, the methionine loops are more exposed, forming hydrophobic patches on the protein surface. These two arrangements suggest that the methionine motifs might function in protein-protein interactions between PcoC molecules or with other methionine-rich proteins such as PcoA. Analytical ultracentrifugation data indicate that a weak monomer-dimer equilibrium exists in solution for the apo protein. Dimerization is significantly enhanced upon binding Cu(I) with a measured delta(deltaG degrees )<or=-8.0 kJ/mole, suggesting that copper might bind at the dimer interface.

-	~~{{STRUCTURE_1ix2\| PDB=1ix2 \| SCENE= }}~~	+	Crystal structure and dimerization equilibria of PcoC, a methionine-rich copper resistance protein from Escherichia coli.,Wernimont AK, Huffman DL, Finney LA, Demeler B, O'Halloran TV, Rosenzweig AC J Biol Inorg Chem. 2003 Jan;8(1-2):185-94. Epub 2002 Sep 27. PMID:12459914<ref>PMID:12459914</ref>

-	~~===Crystal Structure of Selenomethionine PcoC~~, a ~~Copper Resistance Protein from Escherichia coli===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12459914}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1ix2]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:012459914<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Demeler, B.]]		[[Category: Demeler, B.]]

OCA: Protected "1ix2" [edit=sysop:move=sysop]

2012-11-28T15:00:31Z

Protected "1ix2" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:00, 28 November 2012

OCA at 15:00, 28 November 2012

2012-11-28T15:00:27Z

←Older revision		Revision as of 15:00, 28 November 2012
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-	{{Seed}}
	[[Image:1ix2.png\|left\|200px]]		[[Image:1ix2.png\|left\|200px]]

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	{{STRUCTURE_1ix2\| PDB=1ix2 \| SCENE= }}		{{STRUCTURE_1ix2\| PDB=1ix2 \| SCENE= }}

	===Crystal Structure of Selenomethionine PcoC, a Copper Resistance Protein from Escherichia coli===		===Crystal Structure of Selenomethionine PcoC, a Copper Resistance Protein from Escherichia coli===

-
-	<!--
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	{{ABSTRACT_PUBMED_12459914}}		{{ABSTRACT_PUBMED_12459914}}

	==About this Structure==		==About this Structure==
-	~~1IX2~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA].	+	[[1ix2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12459914~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012459914</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Demeler, B.]]		[[Category: Demeler, B.]]
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	[[Category: Wernimont, A K.]]		[[Category: Wernimont, A K.]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
		+	[[Category: Metal binding protein]]
	[[Category: Polymethionine cluster]]		[[Category: Polymethionine cluster]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:39:34 2009''

OCA at 20:39, 16 February 2009

2009-02-16T20:39:40Z

←Older revision		Revision as of 20:39, 16 February 2009
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	==About this Structure==		==About this Structure==
-	1IX2 is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA].	+	1IX2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX2 OCA].

	==Reference==		==Reference==
-	Crystal structure and dimerization equilibria of PcoC, a methionine-rich copper resistance protein from Escherichia coli., Wernimont AK, Huffman DL, Finney LA, Demeler B, O'Halloran TV, Rosenzweig AC, J Biol Inorg Chem. 2003 Jan;8(1-2):185-94. Epub 2002 Sep 27. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/12459914 12459914]~~	+	<ref group="xtra">PMID:12459914</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Single protein]]
	[[Category: Demeler, B.]]		[[Category: Demeler, B.]]
	[[Category: Finney, L A.]]		[[Category: Finney, L A.]]
Line 35:		Line 34:
	[[Category: Polymethionine cluster]]		[[Category: Polymethionine cluster]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 1 14~~:09:~~06 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:39:34 2009''