1j22 - Revision history

OCA at 23:41, 27 December 2023

2023-12-27T23:41:01Z

←Older revision		Revision as of 23:41, 27 December 2023
Line 3:		Line 3:
	<StructureSection load='1j22' size='340' side='right'caption='[[1j22]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1j22' size='340' side='right'caption='[[1j22]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Pyrfu Pyrfu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J22 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J22 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[1j23\|1j23]]~~, [[~~1j24~~\|~~1j24~~]]~~, [[1j25\|1j25]]</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j22 OCA], [https://pdbe.org/1j22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j22 RCSB], [https://www.ebi.ac.uk/pdbsum/1j22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j22 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j22 OCA], [https://pdbe.org/1j22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j22 RCSB], [https://www.ebi.ac.uk/pdbsum/1j22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j22 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8TZH8_PYRFU Q8TZH8_PYRFU]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pyrfu~~]]	+	[[Category: Pyrococcus furiosus DSM 3638]]
-	[[Category: Ishino, Y]]	+	[[Category: Ishino Y]]
-	[[Category: Komori, K]]	+	[[Category: Komori K]]
-	[[Category: Morikawa, K]]	+	[[Category: Morikawa K]]
-	[[Category: Nishino, T]]	+	[[Category: Nishino T]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Structure-specific endonuclease~~]]	+

OCA at 07:15, 14 April 2021

2021-04-14T07:15:50Z

←Older revision		Revision as of 07:15, 14 April 2021
Line 3:		Line 3:
	<StructureSection load='1j22' size='340' side='right'caption='[[1j22]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1j22' size='340' side='right'caption='[[1j22]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1J22 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J22 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j23\|1j23]], [[1j24\|1j24]], [[1j25\|1j25]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1j23\|1j23]], [[1j24\|1j24]], [[1j25\|1j25]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1j22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j22 OCA], [~~http~~://pdbe.org/1j22 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1j22 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1j22 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1j22 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j22 OCA], [https://pdbe.org/1j22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j22 RCSB], [https://www.ebi.ac.uk/pdbsum/1j22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j22 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:13, 10 July 2019

2019-07-10T07:13:42Z

←Older revision		Revision as of 07:13, 10 July 2019
Line 1:		Line 1:

	==Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, selenomet derivative==		==Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, selenomet derivative==
-	<StructureSection load='1j22' size='340' side='right' caption='[[1j22]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='1j22' size='340' side='right'caption='[[1j22]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J22 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J22 FirstGlance]. <br>
Line 11:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j2/1j22_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j2/1j22_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 30:		Line 30:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Pyrfu]]		[[Category: Pyrfu]]
	[[Category: Ishino, Y]]		[[Category: Ishino, Y]]

OCA at 09:44, 4 October 2017

2017-10-04T09:44:32Z

←Older revision		Revision as of 09:44, 4 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, selenomet derivative==		==Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, selenomet derivative==
	<StructureSection load='1j22' size='340' side='right' caption='[[1j22]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1j22' size='340' side='right' caption='[[1j22]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J22 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J22 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j23\|1j23]], [[1j24\|1j24]], [[1j25\|1j25]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j23\|1j23]], [[1j24\|1j24]], [[1j25\|1j25]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j22 OCA], [http://pdbe.org/1j22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1j22 RCSB], [http://www.ebi.ac.uk/pdbsum/1j22 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j22 OCA], [http://pdbe.org/1j22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1j22 RCSB], [http://www.ebi.ac.uk/pdbsum/1j22 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1j22 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j22 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:25, 11 September 2015

2015-09-11T15:25:42Z

←Older revision		Revision as of 15:25, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1j22' size='340' side='right' caption='[[1j22]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1j22' size='340' side='right' caption='[[1j22]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pyrococcus_furiosus Pyrococcus furiosus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J22 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J22 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j23\|1j23]], [[1j24\|1j24]], [[1j25\|1j25]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j23\|1j23]], [[1j24\|1j24]], [[1j25\|1j25]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j22 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j22 RCSB], [http://www.ebi.ac.uk/pdbsum/1j22 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j22 OCA], [http://pdbe.org/1j22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1j22 RCSB], [http://www.ebi.ac.uk/pdbsum/1j22 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1j22" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pyrococcus furiosus~~]]	+	[[Category: Pyrfu]]
	[[Category: Ishino, Y]]		[[Category: Ishino, Y]]
	[[Category: Komori, K]]		[[Category: Komori, K]]

OCA at 12:06, 2 January 2015

2015-01-02T12:06:43Z

←Older revision		Revision as of 12:06, 2 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J22 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J22 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j23\|1j23]], [[1j24\|1j24]], [[1j25\|1j25]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j23\|1j23]], [[1j24\|1j24]], [[1j25\|1j25]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j22 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j22 RCSB], [http://www.ebi.ac.uk/pdbsum/1j22 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j22 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j22 RCSB], [http://www.ebi.ac.uk/pdbsum/1j22 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Pyrococcus furiosus]]		[[Category: Pyrococcus furiosus]]
-	[[Category: Ishino, Y.]]	+	[[Category: Ishino, Y]]
-	[[Category: Komori, K.]]	+	[[Category: Komori, K]]
-	[[Category: Morikawa, K.]]	+	[[Category: Morikawa, K]]
-	[[Category: Nishino, T.]]	+	[[Category: Nishino, T]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Structure-specific endonuclease]]		[[Category: Structure-specific endonuclease]]

OCA at 13:31, 28 September 2014

2014-09-28T13:31:44Z

←Older revision		Revision as of 13:31, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1j22.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, selenomet derivative==
		+	<StructureSection load='1j22' size='340' side='right' caption='[[1j22]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1j22]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J22 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j23\|1j23]], [[1j24\|1j24]], [[1j25\|1j25]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j22 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j22 RCSB], [http://www.ebi.ac.uk/pdbsum/1j22 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j2/1j22_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The XPF/Rad1/Mus81-dependent nuclease family specifically cleaves branched structures generated during DNA repair, replication, and recombination, and is essential for maintaining genome stability. Here, we report the domain organization of an archaeal homolog (Hef) of this family and the X-ray crystal structure of the middle domain, with the nuclease activity. The nuclease domain architecture exhibits remarkable similarity to those of restriction endonucleases, including the correspondence of the GDX(n)ERKX(3)D signature motif in Hef to the PDX(n)(E/D)XK motif in restriction enzymes. This structural study also suggests that the XPF/Rad1/Mus81/ERCC1 proteins form a dimer through each interface of the nuclease domain and the helix-hairpin-helix domain. Simultaneous disruptions of both interfaces result in their dissociation into separate monomers, with strikingly reduced endonuclease activities.

-	~~{{STRUCTURE_1j22\| PDB=1j22 \| SCENE= }}~~	+	X-ray and biochemical anatomy of an archaeal XPF/Rad1/Mus81 family nuclease: similarity between its endonuclease domain and restriction enzymes.,Nishino T, Komori K, Ishino Y, Morikawa K Structure. 2003 Apr;11(4):445-57. PMID:12679022<ref>PMID:12679022</ref>

-	~~===Crystal structure of archaeal XPF~~/~~Mus81 homolog~~, ~~Hef from Pyrococcus furiosus, nuclease domain, selenomet derivative===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12679022}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1j22]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:012679022<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Pyrococcus furiosus]]		[[Category: Pyrococcus furiosus]]
	[[Category: Ishino, Y.]]		[[Category: Ishino, Y.]]

OCA: Protected "1j22" [edit=sysop:move=sysop]

2012-11-28T14:56:14Z

Protected "1j22" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:56, 28 November 2012

OCA at 14:56, 28 November 2012

2012-11-28T14:56:11Z

←Older revision		Revision as of 14:56, 28 November 2012
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	[[Image:1j22.png\|left\|200px]]		[[Image:1j22.png\|left\|200px]]

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	{{STRUCTURE_1j22\| PDB=1j22 \| SCENE= }}		{{STRUCTURE_1j22\| PDB=1j22 \| SCENE= }}

	===Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, selenomet derivative===		===Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, selenomet derivative===

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	{{ABSTRACT_PUBMED_12679022}}		{{ABSTRACT_PUBMED_12679022}}

	==About this Structure==		==About this Structure==
-	~~1J22~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/~~Pyrococcus_furiosus_dsm_3638~~ Pyrococcus furiosus ~~dsm 3638~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA].	+	[[1j22]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12679022~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012679022</ref><references group="xtra"/>
-	[[Category: Pyrococcus furiosus ~~dsm 3638~~]]	+	[[Category: Pyrococcus furiosus]]
	[[Category: Ishino, Y.]]		[[Category: Ishino, Y.]]
	[[Category: Komori, K.]]		[[Category: Komori, K.]]
	[[Category: Morikawa, K.]]		[[Category: Morikawa, K.]]
	[[Category: Nishino, T.]]		[[Category: Nishino, T.]]
		+	[[Category: Hydrolase]]
	[[Category: Structure-specific endonuclease]]		[[Category: Structure-specific endonuclease]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:06:36 2009''

OCA at 00:06, 18 February 2009

2009-02-18T00:06:38Z

←Older revision		Revision as of 00:06, 18 February 2009
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	==About this Structure==		==About this Structure==
-	1J22 is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus_dsm_3638 Pyrococcus furiosus dsm 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA].	+	1J22 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus_dsm_3638 Pyrococcus furiosus dsm 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J22 OCA].

	==Reference==		==Reference==
-	X-ray and biochemical anatomy of an archaeal XPF/Rad1/Mus81 family nuclease: similarity between its endonuclease domain and restriction enzymes., Nishino T, Komori K, Ishino Y, Morikawa K, Structure. 2003 Apr;11(4):445-57. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/12679022 12679022]~~	+	<ref group="xtra">PMID:12679022</ref><references group="xtra"/>
	[[Category: Pyrococcus furiosus dsm 3638]]		[[Category: Pyrococcus furiosus dsm 3638]]
-	[[Category: Single protein]]
	[[Category: Ishino, Y.]]		[[Category: Ishino, Y.]]
	[[Category: Komori, K.]]		[[Category: Komori, K.]]
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	[[Category: Structure-specific endonuclease]]		[[Category: Structure-specific endonuclease]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 1 14~~:23:~~08 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:06:36 2009''