1jiw - Revision history

OCA at 08:41, 16 August 2023

2023-08-16T08:41:28Z

←Older revision		Revision as of 08:41, 16 August 2023
Line 3:		Line 3:
	<StructureSection load='1jiw' size='340' side='right'caption='[[1jiw]], [[Resolution\|resolution]] 1.74Å' scene=''>		<StructureSection load='1jiw' size='340' side='right'caption='[[1jiw]], [[Resolution\|resolution]] 1.74Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jiw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JIW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jiw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JIW FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~, ~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.74Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height~~: ~~3em;~~'>~~[[1smp\|1smp]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jiw OCA], [https://pdbe.org/1jiw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jiw RCSB], [https://www.ebi.ac.uk/pdbsum/1jiw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jiw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jiw OCA], [https://pdbe.org/1jiw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jiw RCSB], [https://www.ebi.ac.uk/pdbsum/1jiw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jiw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/INH_PSEAE INH_PSEAE]] Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity).	+	[https://www.uniprot.org/uniprot/INH_PSEAE INH_PSEAE] Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Baumann, U~~]]	+	[[Category: Pseudomonas aeruginosa]]
-	[[Category: ~~Feltzer, R E~~]]	+	[[Category: Baumann U]]
-	[[Category: ~~Gray, R D~~]]	+	[[Category: Feltzer RE]]
-	[[Category: ~~Hege, T~~]]	+	[[Category: Gray RD]]
-	[[Category: ~~Hydrolase-hydrolase inhibitor complex]]~~	+	[[Category: Hege T]]
-	~~[[Category: Pseudomonas aeruginosa alkaline protease inhibitor~~]]	+

OCA at 06:41, 11 August 2021

2021-08-11T06:41:22Z

←Older revision		Revision as of 06:41, 11 August 2021
Line 3:		Line 3:
	<StructureSection load='1jiw' size='340' side='right'caption='[[1jiw]], [[Resolution\|resolution]] 1.74Å' scene=''>		<StructureSection load='1jiw' size='340' side='right'caption='[[1jiw]], [[Resolution\|resolution]] 1.74Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jiw]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1JIW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jiw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JIW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1smp\|1smp]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1smp\|1smp]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1jiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jiw OCA], [~~http~~://pdbe.org/1jiw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1jiw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1jiw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1jiw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jiw OCA], [https://pdbe.org/1jiw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jiw RCSB], [https://www.ebi.ac.uk/pdbsum/1jiw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jiw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/INH_PSEAE INH_PSEAE]] Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity).	+	[[https://www.uniprot.org/uniprot/INH_PSEAE INH_PSEAE]] Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 09:19, 6 November 2019

2019-11-06T09:19:25Z

←Older revision		Revision as of 09:19, 6 November 2019
Line 1:		Line 1:

	==Crystal structure of the APR-APRin complex==		==Crystal structure of the APR-APRin complex==
-	<StructureSection load='1jiw' size='340' side='right' caption='[[1jiw]], [[Resolution\|resolution]] 1.74Å' scene=''>	+	<StructureSection load='1jiw' size='340' side='right'caption='[[1jiw]], [[Resolution\|resolution]] 1.74Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1jiw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JIW FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jiw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JIW FirstGlance]. <br>
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Baumann, U]]		[[Category: Baumann, U]]
	[[Category: Feltzer, R E]]		[[Category: Feltzer, R E]]

OCA at 08:56, 17 January 2018

2018-01-17T08:56:07Z

←Older revision		Revision as of 08:56, 17 January 2018
Line 1:		Line 1:
		+
	==Crystal structure of the APR-APRin complex==		==Crystal structure of the APR-APRin complex==
	<StructureSection load='1jiw' size='340' side='right' caption='[[1jiw]], [[Resolution\|resolution]] 1.74Å' scene=''>		<StructureSection load='1jiw' size='340' side='right' caption='[[1jiw]], [[Resolution\|resolution]] 1.74Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1smp\|1smp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1smp\|1smp]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jiw OCA], [http://pdbe.org/1jiw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jiw RCSB], [http://www.ebi.ac.uk/pdbsum/1jiw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jiw OCA], [http://pdbe.org/1jiw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jiw RCSB], [http://www.ebi.ac.uk/pdbsum/1jiw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jiw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/1jiw_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/1jiw_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 18:25, 8 February 2016

2016-02-08T18:25:17Z

←Older revision		Revision as of 18:25, 8 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jiw ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:13, 10 September 2015

2015-09-10T14:13:21Z

←Older revision		Revision as of 14:13, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1jiw' size='340' side='right' caption='[[1jiw]], [[Resolution\|resolution]] 1.74Å' scene=''>		<StructureSection load='1jiw' size='340' side='right' caption='[[1jiw]], [[Resolution\|resolution]] 1.74Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jiw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_aeruginosa Pseudomonas aeruginosa~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JIW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jiw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JIW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1smp\|1smp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1smp\|1smp]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jiw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jiw RCSB], [http://www.ebi.ac.uk/pdbsum/1jiw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jiw OCA], [http://pdbe.org/1jiw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jiw RCSB], [http://www.ebi.ac.uk/pdbsum/1jiw PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1jiw" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Pseudomonas aeruginosa]]
	[[Category: Baumann, U]]		[[Category: Baumann, U]]
	[[Category: Feltzer, R E]]		[[Category: Feltzer, R E]]

OCA at 01:17, 25 December 2014

2014-12-25T01:17:18Z

←Older revision		Revision as of 01:17, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1jiw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JIW FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jiw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JIW FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1smp\|1smp]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1smp\|1smp]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jiw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jiw RCSB], [http://www.ebi.ac.uk/pdbsum/1jiw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jiw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jiw RCSB], [http://www.ebi.ac.uk/pdbsum/1jiw PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/INH_PSEAE INH_PSEAE]] Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
-	[[Category: Baumann, U.]]	+	[[Category: Baumann, U]]
-	[[Category: Feltzer, R E.]]	+	[[Category: Feltzer, R E]]
-	[[Category: Gray, R D.]]	+	[[Category: Gray, R D]]
-	[[Category: Hege, T.]]	+	[[Category: Hege, T]]
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]
	[[Category: Pseudomonas aeruginosa alkaline protease inhibitor]]		[[Category: Pseudomonas aeruginosa alkaline protease inhibitor]]

OCA at 12:38, 28 September 2014

2014-09-28T12:38:40Z

←Older revision		Revision as of 12:38, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1jiw.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of the APR-APRin complex==
		+	<StructureSection load='1jiw' size='340' side='right' caption='[[1jiw]], [[Resolution\|resolution]] 1.74Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1jiw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JIW FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1smp\|1smp]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jiw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jiw RCSB], [http://www.ebi.ac.uk/pdbsum/1jiw PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/1jiw_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Serralysins are a family of metalloproteases secreted by Gram-negative bacteria into the medium in the form of inactive zymogens. Usually, all serralysin secretors have on the same operon a gene coding for a periplasmic 10-kDa protein, which is an inhibitor of the secreted protease. The recent characterization of the inhibitor of the alkaline protease from Pseudomonas aeruginosa revealed a surprisingly low dissociation constant of 4 pm, contrary to earlier studies on homologous systems, where inhibition constants in the microm range were reported. To approach a more accurate understanding, the crystal structure of the complex between inhibitor and protease from P. aeruginosa was determined at 1.74 A resolution and refined to R(free) = 0.204. The structure reported here shows clearly that the N terminus of the inhibitor forms a coordinative bond to the catalytic Zn(2+) ion with a nitrogen-zinc distance of 2.17 A. We conclude that this interaction adds substantially to the complex stability and show also that similar interactions are found in other metzincin-inhibitor complexes.

-	~~{{STRUCTURE_1jiw\| PDB=1jiw \| SCENE= }}~~	+	Crystal structure of a complex between Pseudomonas aeruginosa alkaline protease and its cognate inhibitor: inhibition by a zinc-NH2 coordinative bond.,Hege T, Feltzer RE, Gray RD, Baumann U J Biol Chem. 2001 Sep 14;276(37):35087-92. Epub 2001 Jul 9. PMID:11445573<ref>PMID:11445573</ref>

-	~~===Crystal structure~~ of the ~~APR-APRin complex===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11445573}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1jiw]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011445573<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
	[[Category: Baumann, U.]]		[[Category: Baumann, U.]]

OCA: Protected "1jiw" [edit=sysop:move=sysop]

2012-12-05T11:34:48Z

Protected "1jiw" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:34, 5 December 2012

OCA at 11:34, 5 December 2012

2012-12-05T11:34:44Z

←Older revision		Revision as of 11:34, 5 December 2012
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-	{{Seed}}
	[[Image:1jiw.png\|left\|200px]]		[[Image:1jiw.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1jiw\| PDB=1jiw \| SCENE= }}		{{STRUCTURE_1jiw\| PDB=1jiw \| SCENE= }}

	===Crystal structure of the APR-APRin complex===		===Crystal structure of the APR-APRin complex===

-
-	<!--
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	{{ABSTRACT_PUBMED_11445573}}		{{ABSTRACT_PUBMED_11445573}}

	==About this Structure==		==About this Structure==
-	~~1JIW~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA].	+	[[1jiw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIW OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11445573~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011445573</ref><references group="xtra"/>
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
	[[Category: Baumann, U.]]		[[Category: Baumann, U.]]
Line 29:		Line 17:
	[[Category: Gray, R D.]]		[[Category: Gray, R D.]]
	[[Category: Hege, T.]]		[[Category: Hege, T.]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
	[[Category: Pseudomonas aeruginosa alkaline protease inhibitor]]		[[Category: Pseudomonas aeruginosa alkaline protease inhibitor]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 01:23:44 2009''