1jml - Revision history

OCA at 08:42, 16 August 2023

2023-08-16T08:42:53Z

←Older revision		Revision as of 08:42, 16 August 2023
Line 3:		Line 3:
	<StructureSection load='1jml' size='340' side='right'caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1jml' size='340' side='right'caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Finm2 Finm2~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JML FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Finegoldia_magna_ATCC_29328 Finegoldia magna ATCC 29328]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JML FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1hz6\|1hz6]], [[1hz5\|1hz5]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [https://pdbe.org/1jml PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [https://www.ebi.ac.uk/pdbsum/1jml PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jml ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [https://pdbe.org/1jml PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [https://www.ebi.ac.uk/pdbsum/1jml PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jml ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q51912_FINMA Q51912_FINMA]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Finm2~~]]	+	[[Category: Finegoldia magna ATCC 29328]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Baker, D]]	+	[[Category: Baker D]]
-	[[Category: Kim~~, D E~~]]	+	[[Category: Kim DE]]
-	[[Category: Kuhlman, B]]	+	[[Category: Kuhlman B]]
-	[[Category: Neill~~, J W.O~~]]	+	[[Category: O'Neill JW]]
-	[[Category: Zhang~~, K Y.J]]~~	+	[[Category: Zhang KYJ]]
-	~~[[Category: Carboxy-terminal beta-strand swapped]]~~	+
-	~~[[Category: Domain swapped dimer]]~~	+
-	~~[[Category: Four stranded beta-sheet with central alpha helix]]~~	+
-	~~[[Category: Protein binding~~]]	+

OCA at 14:32, 27 October 2021

2021-10-27T14:32:19Z

←Older revision		Revision as of 14:32, 27 October 2021
Line 3:		Line 3:
	<StructureSection load='1jml' size='340' side='right'caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1jml' size='340' side='right'caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Finm2 Finm2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1JML FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Finm2 Finm2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JML FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hz6\|1hz6]], [[1hz5\|1hz5]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hz6\|1hz6]], [[1hz5\|1hz5]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [~~http~~://pdbe.org/1jml PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1jml PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1jml ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [https://pdbe.org/1jml PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [https://www.ebi.ac.uk/pdbsum/1jml PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jml ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 10:35, 16 September 2020

2020-09-16T10:35:49Z

←Older revision		Revision as of 10:35, 16 September 2020
Line 1:		Line 1:

	==Conversion of Monomeric Protein L to an Obligate Dimer by Computational Protein Design==		==Conversion of Monomeric Protein L to an Obligate Dimer by Computational Protein Design==
-	<StructureSection load='1jml' size='340' side='right' caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='1jml' size='340' side='right'caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Finm2 Finm2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1JML FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Finm2 Finm2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1JML FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hz6\|1hz6]], [[1hz5\|1hz5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hz6\|1hz6]], [[1hz5\|1hz5]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [http://pdbe.org/1jml PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [http://www.ebi.ac.uk/pdbsum/1jml PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jml ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [http://pdbe.org/1jml PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [http://www.ebi.ac.uk/pdbsum/1jml PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jml ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Finm2]]		[[Category: Finm2]]
		+	[[Category: Large Structures]]
	[[Category: Baker, D]]		[[Category: Baker, D]]
	[[Category: Kim, D E]]		[[Category: Kim, D E]]

OCA at 07:52, 12 December 2018

2018-12-12T07:52:03Z

←Older revision		Revision as of 07:52, 12 December 2018
Line 3:		Line 3:
	<StructureSection load='1jml' size='340' side='right' caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1jml' size='340' side='right' caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JML FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Finm2 Finm2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JML FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hz6\|1hz6]], [[1hz5\|1hz5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hz6\|1hz6]], [[1hz5\|1hz5]]</td></tr>
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jm/1jml_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jm/1jml_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 31:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Finm2]]
	[[Category: Baker, D]]		[[Category: Baker, D]]
	[[Category: Kim, D E]]		[[Category: Kim, D E]]

OCA at 11:10, 1 February 2017

2017-02-01T11:10:14Z

←Older revision		Revision as of 11:10, 1 February 2017
Line 1:		Line 1:
		+
	==Conversion of Monomeric Protein L to an Obligate Dimer by Computational Protein Design==		==Conversion of Monomeric Protein L to an Obligate Dimer by Computational Protein Design==
	<StructureSection load='1jml' size='340' side='right' caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1jml' size='340' side='right' caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Finm2 Finm2]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JML FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JML FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hz6\|1hz6]], [[1hz5\|1hz5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hz6\|1hz6]], [[1hz5\|1hz5]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [http://pdbe.org/1jml PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [http://www.ebi.ac.uk/pdbsum/1jml PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [http://pdbe.org/1jml PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [http://www.ebi.ac.uk/pdbsum/1jml PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jml ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 30:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Finm2]]
	[[Category: Baker, D]]		[[Category: Baker, D]]
	[[Category: Kim, D E]]		[[Category: Kim, D E]]

OCA at 04:08, 8 February 2016

2016-02-08T04:08:25Z

←Older revision		Revision as of 04:08, 8 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jml ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:42, 10 September 2015

2015-09-10T07:42:34Z

←Older revision		Revision as of 07:42, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1jml' size='340' side='right' caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1jml' size='340' side='right' caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Finegoldia_magna_atcc_29328 Finegoldia magna atcc 29328~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JML FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Finm2 Finm2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JML FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hz6\|1hz6]], [[1hz5\|1hz5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hz6\|1hz6]], [[1hz5\|1hz5]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [http://www.ebi.ac.uk/pdbsum/1jml PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [http://pdbe.org/1jml PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [http://www.ebi.ac.uk/pdbsum/1jml PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1jml" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Finegoldia magna atcc 29328~~]]	+	[[Category: Finm2]]
	[[Category: Baker, D]]		[[Category: Baker, D]]
	[[Category: Kim, D E]]		[[Category: Kim, D E]]

OCA at 12:19, 2 January 2015

2015-01-02T12:19:10Z

←Older revision		Revision as of 12:19, 2 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Finegoldia_magna_atcc_29328 Finegoldia magna atcc 29328]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JML FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Finegoldia_magna_atcc_29328 Finegoldia magna atcc 29328]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JML FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hz6\|1hz6]], [[1hz5\|1hz5]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hz6\|1hz6]], [[1hz5\|1hz5]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [http://www.ebi.ac.uk/pdbsum/1jml PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [http://www.ebi.ac.uk/pdbsum/1jml PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Finegoldia magna atcc 29328]]		[[Category: Finegoldia magna atcc 29328]]
-	[[Category: Baker, D.]]	+	[[Category: Baker, D]]
-	[[Category: Kim, D E.]]	+	[[Category: Kim, D E]]
	[[Category: Kuhlman, B]]		[[Category: Kuhlman, B]]
-	[[Category: Neill, J W.O.]]	+	[[Category: Neill, J W.O]]
-	[[Category: Zhang, K Y.J.]]	+	[[Category: Zhang, K Y.J]]
-	[[Category: Carboxy-terminal beta-strand swapped.]]	+	[[Category: Carboxy-terminal beta-strand swapped]]
	[[Category: Domain swapped dimer]]		[[Category: Domain swapped dimer]]
	[[Category: Four stranded beta-sheet with central alpha helix]]		[[Category: Four stranded beta-sheet with central alpha helix]]
	[[Category: Protein binding]]		[[Category: Protein binding]]

OCA at 12:35, 28 September 2014

2014-09-28T12:35:19Z

←Older revision		Revision as of 12:35, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1jml.~~png~~\|~~left~~\|200px]]	+	==Conversion of Monomeric Protein L to an Obligate Dimer by Computational Protein Design==
		+	<StructureSection load='1jml' size='340' side='right' caption='[[1jml]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1jml]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Finegoldia_magna_atcc_29328 Finegoldia magna atcc 29328]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JML FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hz6\|1hz6]], [[1hz5\|1hz5]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jml OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jml RCSB], [http://www.ebi.ac.uk/pdbsum/1jml PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jm/1jml_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Protein L consists of a single alpha-helix packed on a four-stranded beta-sheet formed by two symmetrically opposed beta-hairpins. We use a computer-based protein design procedure to stabilize a domain-swapped dimer of protein L in which the second beta-turn straightens and the C-terminal strand inserts into the beta-sheet of the partner. The designed obligate dimer contains three mutations (A52V, N53P, and G55A) and has a dissociation constant of approximately 700 pM, which is comparable to the dissociation constant of many naturally occurring protein dimers. The structure of the dimer has been determined by x-ray crystallography and is close to the in silico model.

-	~~{{STRUCTURE_1jml\| PDB=1jml \| SCENE= }}~~	+	Conversion of monomeric protein L to an obligate dimer by computational protein design.,Kuhlman B, O'Neill JW, Kim DE, Zhang KY, Baker D Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10687-91. Epub 2001 Aug 28. PMID:11526208<ref>PMID:11526208</ref>

-	~~===Conversion~~ of ~~Monomeric Protein L to an Obligate Dimer by Computational Protein Design===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11526208}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1jml]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Finegoldia_magna_atcc_29328 Finegoldia magna atcc 29328]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1JML OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011526208<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Finegoldia magna atcc 29328]]		[[Category: Finegoldia magna atcc 29328]]
	[[Category: Baker, D.]]		[[Category: Baker, D.]]

OCA: Protected "1jml" [edit=sysop:move=sysop]

2012-12-05T11:29:34Z

Protected "1jml" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:29, 5 December 2012