1k17 - Revision history

OCA at 06:47, 11 August 2021

2021-08-11T06:47:56Z

←Older revision		Revision as of 06:47, 11 August 2021
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	<StructureSection load='1k17' size='340' side='right'caption='[[1k17]]' scene=''>		<StructureSection load='1k17' size='340' side='right'caption='[[1k17]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1K17 FirstGlance]. <br>	+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K17 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1k17 FirstGlance], [~~http~~://www.ebi.ac.uk/pdbsum/1k17 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1k17 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k17 FirstGlance], [https://www.ebi.ac.uk/pdbsum/1k17 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k17 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:08, 6 November 2019

2019-11-06T09:08:31Z

←Older revision		Revision as of 09:08, 6 November 2019
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	==ALIPHATIC AMIDASE (EC 3.5.1.4)==		==ALIPHATIC AMIDASE (EC 3.5.1.4)==
-	<StructureSection load='1k17' size='340' side='right' caption='[[1k17]]' scene=''>	+	<StructureSection load='1k17' size='340' side='right'caption='[[1k17]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K17 FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K17 FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Theoretical Model]]		[[Category: Theoretical Model]]
		+	[[Category: Large Structures]]
	[[Category: Brown, P R]]		[[Category: Brown, P R]]
	[[Category: Clemente, A]]		[[Category: Clemente, A]]

OCA at 21:18, 24 January 2018

2018-01-24T21:18:29Z

←Older revision		Revision as of 21:18, 24 January 2018
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K17 FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K17 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k17 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1k17 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k17 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1k17 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1k17 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:08, 11 February 2016

2016-02-11T09:08:44Z

←Older revision		Revision as of 09:08, 11 February 2016
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		+	{{Theoretical_model}}
		+
	==ALIPHATIC AMIDASE (EC 3.5.1.4)==		==ALIPHATIC AMIDASE (EC 3.5.1.4)==
	<StructureSection load='1k17' size='340' side='right' caption='[[1k17]]' scene=''>		<StructureSection load='1k17' size='340' side='right' caption='[[1k17]]' scene=''>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Theoretical Model]]
	[[Category: Brown, P R]]		[[Category: Brown, P R]]
	[[Category: Clemente, A]]		[[Category: Clemente, A]]

OCA at 07:32, 11 September 2015

2015-09-11T07:32:47Z

←Older revision		Revision as of 07:32, 11 September 2015
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1k17" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 15:27, 5 January 2015

2015-01-05T15:27:40Z

←Older revision		Revision as of 15:27, 5 January 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K17 FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K17 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k17 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1k17 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k17 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1k17 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 11:44, 28 September 2014

2014-09-28T11:44:10Z

←Older revision		Revision as of 11:44, 28 September 2014
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-	~~{{Theoretical_model}}~~	+	==ALIPHATIC AMIDASE (EC 3.5.1.4)==
		+	<StructureSection load='1k17' size='340' side='right' caption='[[1k17]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K17 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k17 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1k17 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The aliphatic amidase from Pseudomonas aeruginosa belongs to the nitrilase superfamily, and Cys(166) is the nucleophile of the catalytic mechanism. A model of amidase was built by comparative modelling using the crystal structure of the worm nitrilase-fragile histidine triad fusion protein (NitFhit; Protein Data Bank accession number 1EMS) as a template. The amidase model predicted a catalytic triad (Cys-Glu-Lys) situated at the bottom of a pocket and identical with the presumptive catalytic triad of NitFhit. Three-dimensional models for other amidases belonging to the nitrilase superfamily also predicted Cys-Glu-Lys catalytic triads. Support for the structure for the P. aeruginosa amidase came from site-direct mutagenesis and from the locations of amino acid residues that altered substrate specificity or binding when mutated.

-	~~[[Image~~:~~1k17~~.~~png\|left\|200px]]~~	+	Support for a three-dimensional structure predicting a Cys-Glu-Lys catalytic triad for Pseudomonas aeruginosa amidase comes from site-directed mutagenesis and mutations altering substrate specificity.,Novo C, Farnaud S, Tata R, Clemente A, Brown PR Biochem J. 2002 Aug 1;365(Pt 3):731-8. PMID:11955282<ref>PMID:11955282</ref>

-	~~{{STRUCTURE_1k17\| PDB=1k17 \| SCENE= }}~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~===ALIPHATIC AMIDASE (EC 3~~.5.1.~~4)===~~	+	== References ==
-		+	<references/>
-	~~{{ABSTRACT_PUBMED_11955282}}~~	+	__TOC__
-		+	</StructureSection>
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011955282<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Brown, P R]]		[[Category: Brown, P R]]
	[[Category: Clemente, A]]		[[Category: Clemente, A]]

OCA: Protected "1k17" [edit=sysop:move=sysop]

2012-10-21T08:48:38Z

Protected "1k17" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:48, 21 October 2012

OCA at 08:48, 21 October 2012

2012-10-21T08:48:34Z

←Older revision		Revision as of 08:48, 21 October 2012
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	{{Theoretical_model}}		{{Theoretical_model}}
-	~~{{Seed}}~~	+
	[[Image:1k17.png\|left\|200px]]		[[Image:1k17.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1k17", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1k17\| PDB=1k17 \| SCENE= }}		{{STRUCTURE_1k17\| PDB=1k17 \| SCENE= }}

	===ALIPHATIC AMIDASE (EC 3.5.1.4)===		===ALIPHATIC AMIDASE (EC 3.5.1.4)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11955282}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11955282 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_11955282}}		{{ABSTRACT_PUBMED_11955282}}
-
-	==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K17 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11955282~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011955282</ref><references group="xtra"/>
	[[Category: Brown, P R]]		[[Category: Brown, P R]]
	[[Category: Clemente, A]]		[[Category: Clemente, A]]
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	[[Category: Novo, C]]		[[Category: Novo, C]]
	[[Category: Tata, R]]		[[Category: Tata, R]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 06:59:52 2010''

OCA at 03:59, 8 April 2010

2010-04-08T03:59:53Z

←Older revision		Revision as of 03:59, 8 April 2010
Line 1:		Line 1:
-	~~'''Theoretical Model'''~~	+	{{Theoretical_model}}
		+	{{Seed}}
		+	[[Image:1k17.png\|left\|200px]]

-	The ~~entry 1K17 is a Theoretical Model titled 'Aliphatic amidase (EC 3~~.~~5.1.4~~)'.	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_1k17", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_1k17\| PDB=1k17 \| SCENE= }}

-	~~[[Category:Theoretical Model]]~~	+	===ALIPHATIC AMIDASE (EC 3.5.1.4)===


-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 30 09~~:50:~~30 2008~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_11955282}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 11955282 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_11955282}}
		+
		+	==About this Structure==
		+	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K17 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:11955282</ref><references group="xtra"/>
		+	[[Category: Brown, P R]]
		+	[[Category: Clemente, A]]
		+	[[Category: Farnaud, S]]
		+	[[Category: Novo, C]]
		+	[[Category: Tata, R]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 06:59:52 2010''