1m1h - Revision history

OCA at 08:30, 10 April 2024

2024-04-10T08:30:19Z

←Older revision		Revision as of 08:30, 10 April 2024
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	<StructureSection load='1m1h' size='340' side='right'caption='[[1m1h]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='1m1h' size='340' side='right'caption='[[1m1h]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex~~ aeolicus~~" huber and stetter 2001~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M1H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M1H FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>~~[[~~1m1g~~\|~~1m1g~~]]~~</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.95Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1h OCA], [https://pdbe.org/1m1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m1h RCSB], [https://www.ebi.ac.uk/pdbsum/1m1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m1h ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1h OCA], [https://pdbe.org/1m1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m1h RCSB], [https://www.ebi.ac.uk/pdbsum/1m1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m1h ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/NUSG_AQUAE NUSG_AQUAE]] Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase (By similarity).	+	[https://www.uniprot.org/uniprot/NUSG_AQUAE NUSG_AQUAE] Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 19:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m1h ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m1h ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Microbial transcription modulator NusG interacts with RNA polymerase and termination factor rho, displaying striking functional homology to eukaryotic Spt5. The protein is also a translational regulator. We have determined crystal structures of Aquifex aeolicus NusG showing a modular design: an N-terminal RNP-like domain, a C-terminal element with a KOW sequence motif and a species-specific immunoglobulin-like fold. The structures reveal bona fide nucleic acid binding sites, and nucleic acid binding activities can be detected for NusG from three organisms and for the KOW element alone. A conserved KOW domain is defined as a new class of nucleic acid binding folds. This module is a close structural homolog of tudor protein-protein interaction motifs. Putative protein binding sites for the RNP and KOW domains can be deduced, which differ from the areas implicated in nucleic acid interactions. The results strongly argue that both protein and nucleic acid contacts are important for NusG's functions and that the factor can act as an adaptor mediating indirect protein-nucleic acid associations.
-
-	Crystal structures of transcription factor NusG in light of its nucleic acid- and protein-binding activities.,Steiner T, Kaiser JT, Marinkovic S, Huber R, Wahl MC EMBO J. 2002 Sep 2;21(17):4641-53. PMID:12198166<ref>PMID:12198166</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1m1h" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Aquifex aeolicus ~~huber and stetter 2001~~]]	+	[[Category: Aquifex aeolicus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Huber, R]]	+	[[Category: Huber R]]
-	[[Category: Kaiser~~, J T~~]]	+	[[Category: Kaiser JT]]
-	[[Category: Marinkovic, S]]	+	[[Category: Marinkovic S]]
-	[[Category: Steiner, T]]	+	[[Category: Steiner T]]
-	[[Category: Wahl~~, M C]]~~	+	[[Category: Wahl MC]]
-	~~[[Category: Antitermination]]~~	+
-	~~[[Category: Immunoglobulin fold]]~~	+
-	~~[[Category: Nucleic acid interaction]]~~	+
-	~~[[Category: Protein-protein interaction]]~~	+
-	~~[[Category: Rnp motif]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Transcription termination~~]]	+

OCA at 06:52, 18 August 2021

2021-08-18T06:52:17Z

←Older revision		Revision as of 06:52, 18 August 2021
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	<StructureSection load='1m1h' size='340' side='right'caption='[[1m1h]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='1m1h' size='340' side='right'caption='[[1m1h]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1M1H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M1H FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m1g\|1m1g]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1m1g\|1m1g]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1m1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1h OCA], [~~http~~://pdbe.org/1m1h PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1m1h RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1m1h PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1m1h ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1h OCA], [https://pdbe.org/1m1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m1h RCSB], [https://www.ebi.ac.uk/pdbsum/1m1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m1h ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/NUSG_AQUAE NUSG_AQUAE]] Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase (By similarity).	+	[[https://www.uniprot.org/uniprot/NUSG_AQUAE NUSG_AQUAE]] Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</div>		</div>
	<div class="pdbe-citations 1m1h" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1m1h" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[RapA%2C a Swi2/Snf2 protein\|RapA%2C a Swi2/Snf2 protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:14, 13 November 2019

2019-11-13T12:14:09Z

←Older revision		Revision as of 12:14, 13 November 2019
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	==Crystal structure of Aquifex aeolicus N-utilization substance G (NusG), Space group I222==		==Crystal structure of Aquifex aeolicus N-utilization substance G (NusG), Space group I222==
-	<StructureSection load='1m1h' size='340' side='right' caption='[[1m1h]], [[Resolution\|resolution]] 1.95Å' scene=''>	+	<StructureSection load='1m1h' size='340' side='right'caption='[[1m1h]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M1H FirstGlance]. <br>		<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M1H FirstGlance]. <br>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Aquifex aeolicus huber and stetter 2001]]		[[Category: Aquifex aeolicus huber and stetter 2001]]
		+	[[Category: Large Structures]]
	[[Category: Huber, R]]		[[Category: Huber, R]]
	[[Category: Kaiser, J T]]		[[Category: Kaiser, J T]]

OCA at 07:50, 31 January 2018

2018-01-31T07:50:03Z

←Older revision		Revision as of 07:50, 31 January 2018
Line 1:		Line 1:
		+
	==Crystal structure of Aquifex aeolicus N-utilization substance G (NusG), Space group I222==		==Crystal structure of Aquifex aeolicus N-utilization substance G (NusG), Space group I222==
	<StructureSection load='1m1h' size='340' side='right' caption='[[1m1h]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='1m1h' size='340' side='right' caption='[[1m1h]], [[Resolution\|resolution]] 1.95Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M1H FirstGlance]. <br>		<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M1H FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m1g\|1m1g]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m1g\|1m1g]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1h OCA], [http://pdbe.org/1m1h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1m1h RCSB], [http://www.ebi.ac.uk/pdbsum/1m1h PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1h OCA], [http://pdbe.org/1m1h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1m1h RCSB], [http://www.ebi.ac.uk/pdbsum/1m1h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1m1h ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m1/1m1h_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m1/1m1h_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 20:34, 7 February 2016

2016-02-07T20:34:40Z

←Older revision		Revision as of 20:34, 7 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m1h ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:46, 10 September 2015

2015-09-10T04:46:17Z

←Older revision		Revision as of 04:46, 10 September 2015
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	<StructureSection load='1m1h' size='340' side='right' caption='[[1m1h]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='1m1h' size='340' side='right' caption='[[1m1h]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Aquifex_aeolicus Aquifex~~ aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M1H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M1H FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m1g\|1m1g]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m1g\|1m1g]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m1h RCSB], [http://www.ebi.ac.uk/pdbsum/1m1h PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1h OCA], [http://pdbe.org/1m1h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1m1h RCSB], [http://www.ebi.ac.uk/pdbsum/1m1h PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1m1h" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Aquifex aeolicus]]	+	[[Category: Aquifex aeolicus huber and stetter 2001]]
	[[Category: Huber, R]]		[[Category: Huber, R]]
	[[Category: Kaiser, J T]]		[[Category: Kaiser, J T]]

OCA at 18:05, 24 December 2014

2014-12-24T18:05:42Z

←Older revision		Revision as of 18:05, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M1H FirstGlance]. <br>		<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M1H FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m1g\|1m1g]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m1g\|1m1g]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m1h RCSB], [http://www.ebi.ac.uk/pdbsum/1m1h PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m1h RCSB], [http://www.ebi.ac.uk/pdbsum/1m1h PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NUSG_AQUAE NUSG_AQUAE]] Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Aquifex aeolicus]]		[[Category: Aquifex aeolicus]]
-	[[Category: Huber, R.]]	+	[[Category: Huber, R]]
-	[[Category: Kaiser, J T.]]	+	[[Category: Kaiser, J T]]
-	[[Category: Marinkovic, S.]]	+	[[Category: Marinkovic, S]]
-	[[Category: Steiner, T.]]	+	[[Category: Steiner, T]]
-	[[Category: Wahl, M C.]]	+	[[Category: Wahl, M C]]
	[[Category: Antitermination]]		[[Category: Antitermination]]
	[[Category: Immunoglobulin fold]]		[[Category: Immunoglobulin fold]]

OCA at 14:31, 29 September 2014

2014-09-29T14:31:24Z

←Older revision		Revision as of 14:31, 29 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1m1h\| PDB=1m1h \| SCENE= }}~~	+	==Crystal structure of Aquifex aeolicus N-utilization substance G (NusG), Space group I222==
-	===Crystal structure of Aquifex aeolicus N-utilization substance G (NusG), Space group I222===	+	<StructureSection load='1m1h' size='340' side='right' caption='[[1m1h]], [[Resolution\|resolution]] 1.95Å' scene=''>
-	~~{{ABSTRACT_PUBMED_12198166}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1m1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M1H FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m1g\|1m1g]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m1h RCSB], [http://www.ebi.ac.uk/pdbsum/1m1h PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m1/1m1h_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Microbial transcription modulator NusG interacts with RNA polymerase and termination factor rho, displaying striking functional homology to eukaryotic Spt5. The protein is also a translational regulator. We have determined crystal structures of Aquifex aeolicus NusG showing a modular design: an N-terminal RNP-like domain, a C-terminal element with a KOW sequence motif and a species-specific immunoglobulin-like fold. The structures reveal bona fide nucleic acid binding sites, and nucleic acid binding activities can be detected for NusG from three organisms and for the KOW element alone. A conserved KOW domain is defined as a new class of nucleic acid binding folds. This module is a close structural homolog of tudor protein-protein interaction motifs. Putative protein binding sites for the RNP and KOW domains can be deduced, which differ from the areas implicated in nucleic acid interactions. The results strongly argue that both protein and nucleic acid contacts are important for NusG's functions and that the factor can act as an adaptor mediating indirect protein-nucleic acid associations.

-	~~==About this Structure==~~	+	Crystal structures of transcription factor NusG in light of its nucleic acid- and protein-binding activities.,Steiner T, Kaiser JT, Marinkovic S, Huber R, Wahl MC EMBO J. 2002 Sep 2;21(17):4641-53. PMID:12198166<ref>PMID:12198166</ref>
-	~~[[1m1h]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Aquifex_aeolicus Aquifex aeolicus]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=1M1H OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[RapA%2C a Swi2/Snf2 protein\|RapA%2C a Swi2/Snf2 protein]]		*[[RapA%2C a Swi2/Snf2 protein\|RapA%2C a Swi2/Snf2 protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:012198166<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Aquifex aeolicus]]		[[Category: Aquifex aeolicus]]
	[[Category: Huber, R.]]		[[Category: Huber, R.]]

OCA at 09:49, 11 March 2013

2013-03-11T09:49:09Z

←Older revision		Revision as of 09:49, 11 March 2013
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-	[[Image:1m1h.png\|left\|200px]]
-
	{{STRUCTURE_1m1h\| PDB=1m1h \| SCENE= }}		{{STRUCTURE_1m1h\| PDB=1m1h \| SCENE= }}
-
	===Crystal structure of Aquifex aeolicus N-utilization substance G (NusG), Space group I222===		===Crystal structure of Aquifex aeolicus N-utilization substance G (NusG), Space group I222===
-
	{{ABSTRACT_PUBMED_12198166}}		{{ABSTRACT_PUBMED_12198166}}

OCA: Protected "1m1h" [edit=sysop:move=sysop]

2012-12-05T20:50:30Z

Protected "1m1h" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:50, 5 December 2012