1miv - Revision history

OCA at 08:36, 10 April 2024

2024-04-10T08:36:53Z

←Older revision		Revision as of 08:36, 10 April 2024
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	<StructureSection load='1miv' size='340' side='right'caption='[[1miv]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='1miv' size='340' side='right'caption='[[1miv]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1miv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_12980 Atcc 12980~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MIV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1miv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MIV FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.5Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~MSE~~:~~SELENOMETHIONINE~~'>~~MSE~~</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;~~'>~~[[1miw\|1miw]], [[1miy\|1miy]]~~</~~div~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1miv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1miv OCA], [https://pdbe.org/1miv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1miv RCSB], [https://www.ebi.ac.uk/pdbsum/1miv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1miv ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1miv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1miv OCA], [https://pdbe.org/1miv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1miv RCSB], [https://www.ebi.ac.uk/pdbsum/1miv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1miv ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CCA_GEOSE CCA_GEOSE]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1miv ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1miv ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	CCA-adding enzymes polymerize CCA onto the 3' terminus of immature tRNAs without using a nucleic acid template. The 3.0 A resolution crystal structures of the CCA-adding enzyme from Bacillus stearothermophilus and its complexes with ATP or CTP reveal a seahorse-shaped subunit consisting of four domains: head, neck, body, and tail. The head is structurally homologous to the palm domain of DNA polymerase beta but has additional structural features and functions. The neck, body, and tail represent new protein folding motifs. The neck provides a specific template for the incoming ATP or CTP, whereas the body and tail may bind tRNA. Each subunit has one active site capable of switching its base specificity between ATP and CTP, an important component of the CCA-adding mechanism.
-
-	Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP.,Li F, Xiong Y, Wang J, Cho HD, Tomita K, Weiner AM, Steitz TA Cell. 2002 Dec 13;111(6):815-24. PMID:12526808<ref>PMID:12526808</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1miv" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[CCA-adding enzyme 3D structures\|CCA-adding enzyme 3D structures]]		*[[CCA-adding enzyme 3D structures\|CCA-adding enzyme 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 12980~~]]	+	[[Category: Geobacillus stearothermophilus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Cho~~, H D~~]]	+	[[Category: Cho HD]]
-	[[Category: Li, F]]	+	[[Category: Li F]]
-	[[Category: Steitz~~, T A~~]]	+	[[Category: Steitz TA]]
-	[[Category: Wang, J]]	+	[[Category: Wang J]]
-	[[Category: Weiner~~, A M~~]]	+	[[Category: Weiner AM]]
-	[[Category: Xiong, Y]]	+	[[Category: Xiong Y]]
-	~~[[Category: Cca-adding enzyme]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Translation]]~~	+
-	~~[[Category: Trna nucleotidyltransferase~~]]	+

OCA at 09:27, 5 May 2021

2021-05-05T09:27:29Z

←Older revision		Revision as of 09:27, 5 May 2021
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	<StructureSection load='1miv' size='340' side='right'caption='[[1miv]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='1miv' size='340' side='right'caption='[[1miv]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1miv]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1MIV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1miv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MIV FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1miw\|1miw]], [[1miy\|1miy]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1miw\|1miw]], [[1miy\|1miy]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1miv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1miv OCA], [~~http~~://pdbe.org/1miv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1miv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1miv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1miv ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1miv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1miv OCA], [https://pdbe.org/1miv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1miv RCSB], [https://www.ebi.ac.uk/pdbsum/1miv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1miv ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:53, 31 July 2019

2019-07-31T07:53:31Z

←Older revision		Revision as of 07:53, 31 July 2019
Line 1:		Line 1:

	==Crystal structure of Bacillus stearothermophilus CCA-adding enzyme==		==Crystal structure of Bacillus stearothermophilus CCA-adding enzyme==
-	<StructureSection load='1miv' size='340' side='right' caption='[[1miv]], [[Resolution\|resolution]] 3.50Å' scene=''>	+	<StructureSection load='1miv' size='340' side='right'caption='[[1miv]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1miv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MIV FirstGlance]. <br>		<table><tr><td colspan='2'>[[1miv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MIV FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1miv_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1miv_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1miv" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1miv" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[CCA-adding enzyme 3D structures\|CCA-adding enzyme 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 33:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 12980]]		[[Category: Atcc 12980]]
		+	[[Category: Large Structures]]
	[[Category: Cho, H D]]		[[Category: Cho, H D]]
	[[Category: Li, F]]		[[Category: Li, F]]

OCA at 10:16, 25 October 2017

2017-10-25T10:16:44Z

←Older revision		Revision as of 10:16, 25 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of Bacillus stearothermophilus CCA-adding enzyme==		==Crystal structure of Bacillus stearothermophilus CCA-adding enzyme==
	<StructureSection load='1miv' size='340' side='right' caption='[[1miv]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='1miv' size='340' side='right' caption='[[1miv]], [[Resolution\|resolution]] 3.50Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1miw\|1miw]], [[1miy\|1miy]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1miw\|1miw]], [[1miy\|1miy]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1miv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1miv OCA], [http://pdbe.org/1miv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1miv RCSB], [http://www.ebi.ac.uk/pdbsum/1miv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1miv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1miv OCA], [http://pdbe.org/1miv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1miv RCSB], [http://www.ebi.ac.uk/pdbsum/1miv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1miv ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1miv ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1miv" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1miv" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[CCA-adding enzyme\|CCA-adding enzyme]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:47, 11 September 2015

2015-09-11T08:47:13Z

←Older revision		Revision as of 08:47, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1miv' size='340' side='right' caption='[[1miv]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='1miv' size='340' side='right' caption='[[1miv]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1miv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Geobacillus_stearothermophilus Geobacillus stearothermophilus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MIV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1miv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MIV FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1miw\|1miw]], [[1miy\|1miy]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1miw\|1miw]], [[1miy\|1miy]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1miv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1miv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1miv RCSB], [http://www.ebi.ac.uk/pdbsum/1miv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1miv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1miv OCA], [http://pdbe.org/1miv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1miv RCSB], [http://www.ebi.ac.uk/pdbsum/1miv PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1miv" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Geobacillus stearothermophilus~~]]	+	[[Category: Atcc 12980]]
	[[Category: Cho, H D]]		[[Category: Cho, H D]]
	[[Category: Li, F]]		[[Category: Li, F]]

OCA at 17:01, 5 January 2015

2015-01-05T17:01:39Z

←Older revision		Revision as of 17:01, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1miv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MIV FirstGlance]. <br>		<table><tr><td colspan='2'>[[1miv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MIV FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1miw\|1miw]], [[1miy\|1miy]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1miw\|1miw]], [[1miy\|1miy]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1miv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1miv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1miv RCSB], [http://www.ebi.ac.uk/pdbsum/1miv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1miv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1miv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1miv RCSB], [http://www.ebi.ac.uk/pdbsum/1miv PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Geobacillus stearothermophilus]]		[[Category: Geobacillus stearothermophilus]]
-	[[Category: Cho, H D.]]	+	[[Category: Cho, H D]]
-	[[Category: Li, F.]]	+	[[Category: Li, F]]
-	[[Category: Steitz, T A.]]	+	[[Category: Steitz, T A]]
-	[[Category: Wang, J.]]	+	[[Category: Wang, J]]
-	[[Category: Weiner, A M.]]	+	[[Category: Weiner, A M]]
-	[[Category: Xiong, Y.]]	+	[[Category: Xiong, Y]]
	[[Category: Cca-adding enzyme]]		[[Category: Cca-adding enzyme]]
	[[Category: Transferase]]		[[Category: Transferase]]
	[[Category: Translation]]		[[Category: Translation]]
	[[Category: Trna nucleotidyltransferase]]		[[Category: Trna nucleotidyltransferase]]

OCA at 16:14, 28 September 2014

2014-09-28T16:14:06Z

←Older revision		Revision as of 16:14, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1miv.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of Bacillus stearothermophilus CCA-adding enzyme==
		+	<StructureSection load='1miv' size='340' side='right' caption='[[1miv]], [[Resolution\|resolution]] 3.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1miv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MIV FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1miw\|1miw]], [[1miy\|1miy]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1miv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1miv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1miv RCSB], [http://www.ebi.ac.uk/pdbsum/1miv PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1miv_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	CCA-adding enzymes polymerize CCA onto the 3' terminus of immature tRNAs without using a nucleic acid template. The 3.0 A resolution crystal structures of the CCA-adding enzyme from Bacillus stearothermophilus and its complexes with ATP or CTP reveal a seahorse-shaped subunit consisting of four domains: head, neck, body, and tail. The head is structurally homologous to the palm domain of DNA polymerase beta but has additional structural features and functions. The neck, body, and tail represent new protein folding motifs. The neck provides a specific template for the incoming ATP or CTP, whereas the body and tail may bind tRNA. Each subunit has one active site capable of switching its base specificity between ATP and CTP, an important component of the CCA-adding mechanism.

-	~~{{STRUCTURE_1miv\| PDB=1miv \| SCENE= }}~~	+	Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP.,Li F, Xiong Y, Wang J, Cho HD, Tomita K, Weiner AM, Steitz TA Cell. 2002 Dec 13;111(6):815-24. PMID:12526808<ref>PMID:12526808</ref>

-	~~===Crystal structure~~ of ~~Bacillus stearothermophilus CCA-adding enzyme===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_12526808}}~~	+	==See Also==
-		+	*[[CCA-adding enzyme\|CCA-adding enzyme]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1miv~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:012526808<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Geobacillus stearothermophilus]]		[[Category: Geobacillus stearothermophilus]]
	[[Category: Cho, H D.]]		[[Category: Cho, H D.]]

OCA: Protected "1miv" [edit=sysop:move=sysop]

2012-12-05T21:19:08Z

Protected "1miv" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:19, 5 December 2012

OCA at 21:19, 5 December 2012

2012-12-05T21:19:05Z

←Older revision		Revision as of 21:19, 5 December 2012
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-	{{Seed}}
	[[Image:1miv.png\|left\|200px]]		[[Image:1miv.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1miv", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1miv\| PDB=1miv \| SCENE= }}		{{STRUCTURE_1miv\| PDB=1miv \| SCENE= }}

	===Crystal structure of Bacillus stearothermophilus CCA-adding enzyme===		===Crystal structure of Bacillus stearothermophilus CCA-adding enzyme===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_12526808}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 12526808 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_12526808}}		{{ABSTRACT_PUBMED_12526808}}

	==About this Structure==		==About this Structure==
-	~~1MIV~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA].	+	[[1miv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12526808~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012526808</ref><references group="xtra"/>
	[[Category: Geobacillus stearothermophilus]]		[[Category: Geobacillus stearothermophilus]]
	[[Category: Cho, H D.]]		[[Category: Cho, H D.]]
Line 32:		Line 20:
	[[Category: Xiong, Y.]]		[[Category: Xiong, Y.]]
	[[Category: Cca-adding enzyme]]		[[Category: Cca-adding enzyme]]
		+	[[Category: Transferase]]
		+	[[Category: Translation]]
	[[Category: Trna nucleotidyltransferase]]		[[Category: Trna nucleotidyltransferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:10:46 2009''

OCA at 16:10, 17 February 2009

2009-02-17T16:10:46Z

←Older revision		Revision as of 16:10, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1MIV is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA].	+	1MIV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIV OCA].

	==Reference==		==Reference==
-	Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP., Li F, Xiong Y, Wang J, Cho HD, Tomita K, Weiner AM, Steitz TA, Cell. 2002 Dec 13;111(6):815-24. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/12526808 12526808]~~	+	<ref group="xtra">PMID:12526808</ref><references group="xtra"/>
	[[Category: Geobacillus stearothermophilus]]		[[Category: Geobacillus stearothermophilus]]
-	[[Category: Single protein]]
	[[Category: Cho, H D.]]		[[Category: Cho, H D.]]
	[[Category: Li, F.]]		[[Category: Li, F.]]
Line 35:		Line 34:
	[[Category: Trna nucleotidyltransferase]]		[[Category: Trna nucleotidyltransferase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu Jul 3 00~~:04:~~09 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:10:46 2009''