1ntx - Revision history

OCA at 08:53, 10 April 2024

2024-04-10T08:53:13Z

←Older revision		Revision as of 08:53, 10 April 2024
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	==SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS==		==SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS==
-	<StructureSection load='1ntx' size='340' side='right'caption='[[1ntx~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='1ntx' size='340' side='right'caption='[[1ntx]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Black_mamba Black mamba~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NTX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NTX FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [https://pdbe.org/1ntx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [https://www.ebi.ac.uk/pdbsum/1ntx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ntx ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [https://pdbe.org/1ntx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [https://www.ebi.ac.uk/pdbsum/1ntx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ntx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~NXS1_DENPO NXS1_DENPO~~]~~] Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site.~~ Binds to ~~the muscular~~ nicotinic acetylcholine receptor.	+	[https://www.uniprot.org/uniprot/3S11_DENPO 3S11_DENPO] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.[UniProtKB:P60775]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ntx ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ntx ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Sequence-specific assignments are presented for the polypeptide backbone protons and a majority of the amino-acid-side-chain protons of alpha-neurotoxin from Dendroaspis polylepis polylepis, and individual amide proton-exchange rates with the solvent are reported. The secondary structure and the hydrogen-bonding patterns in the regular secondary structure elements are deduced from nuclear Overhauser effects and the sequence locations of the slowly exchanging amide protons. The molecule includes a three-stranded antiparallel beta-sheet, and there are indications that two additional short chain segments are arranged in an antiparallel beta-sheet. These structural elements are similar, but not identical, to either the secondary structure reported for erabutoxin b in single crystals, or the solution structure of cytotoxin CTXIIb from Naja mossambica mossambica.
-
-	Secondary structure determination for alpha-neurotoxin from Dendroaspis polylepis polylepis based on sequence-specific 1H-nuclear-magnetic-resonance assignments.,Labhardt AM, Hunziker-Kwik EH, Wuthrich K Eur J Biochem. 1988 Nov 1;177(2):295-305. PMID:2847926<ref>PMID:2847926</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1ntx" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Black mamba~~]]	+	[[Category: Dendroaspis polylepis polylepis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Brown~~, L R~~]]	+	[[Category: Brown LR]]
-	[[Category: Wuthrich, K]]	+	[[Category: Wuthrich K]]
-	~~[[Category: Neurotoxin~~]]	+

OCA at 07:06, 25 August 2021

2021-08-25T07:06:12Z

←Older revision		Revision as of 07:06, 25 August 2021
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	<StructureSection load='1ntx' size='340' side='right'caption='[[1ntx]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1ntx' size='340' side='right'caption='[[1ntx]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Black_mamba Black mamba]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1NTX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Black_mamba Black mamba]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NTX FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [~~http~~://pdbe.org/1ntx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ntx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ntx ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [https://pdbe.org/1ntx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [https://www.ebi.ac.uk/pdbsum/1ntx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ntx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/NXS1_DENPO NXS1_DENPO]] Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to the muscular nicotinic acetylcholine receptor.	+	[[https://www.uniprot.org/uniprot/NXS1_DENPO NXS1_DENPO]] Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to the muscular nicotinic acetylcholine receptor.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 18:38, 20 November 2019

2019-11-20T18:38:50Z

←Older revision		Revision as of 18:38, 20 November 2019
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	==SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS==		==SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS==
-	<StructureSection load='1ntx' size='340' side='right' caption='[[1ntx]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='1ntx' size='340' side='right'caption='[[1ntx]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_mamba Black mamba]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NTX FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_mamba Black mamba]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NTX FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Black mamba]]		[[Category: Black mamba]]
		+	[[Category: Large Structures]]
	[[Category: Brown, L R]]		[[Category: Brown, L R]]
	[[Category: Wuthrich, K]]		[[Category: Wuthrich, K]]
	[[Category: Neurotoxin]]		[[Category: Neurotoxin]]

OCA at 07:25, 7 February 2018

2018-02-07T07:25:30Z

←Older revision		Revision as of 07:25, 7 February 2018
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		+
	==SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS==		==SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS==
	<StructureSection load='1ntx' size='340' side='right' caption='[[1ntx]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1ntx' size='340' side='right' caption='[[1ntx]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_mamba Black mamba]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NTX FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_mamba Black mamba]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NTX FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [http://pdbe.org/1ntx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [http://www.ebi.ac.uk/pdbsum/1ntx PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [http://pdbe.org/1ntx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [http://www.ebi.ac.uk/pdbsum/1ntx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ntx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nt/1ntx_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nt/1ntx_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 09:53, 8 February 2016

2016-02-08T09:53:16Z

←Older revision		Revision as of 09:53, 8 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ntx ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:24, 10 September 2015

2015-09-10T10:24:37Z

←Older revision		Revision as of 10:24, 10 September 2015
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	<StructureSection load='1ntx' size='340' side='right' caption='[[1ntx]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1ntx' size='340' side='right' caption='[[1ntx]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NTX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_mamba Black mamba]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NTX FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [http://www.ebi.ac.uk/pdbsum/1ntx PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [http://pdbe.org/1ntx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [http://www.ebi.ac.uk/pdbsum/1ntx PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ntx" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Dendroaspis polylepis polylepis~~]]	+	[[Category: Black mamba]]
	[[Category: Brown, L R]]		[[Category: Brown, L R]]
	[[Category: Wuthrich, K]]		[[Category: Wuthrich, K]]
	[[Category: Neurotoxin]]		[[Category: Neurotoxin]]

OCA at 22:28, 24 December 2014

2014-12-24T22:28:12Z

←Older revision		Revision as of 22:28, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NTX FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NTX FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [http://www.ebi.ac.uk/pdbsum/1ntx PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [http://www.ebi.ac.uk/pdbsum/1ntx PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NXS1_DENPO NXS1_DENPO]] Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to the muscular nicotinic acetylcholine receptor.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Dendroaspis polylepis polylepis]]		[[Category: Dendroaspis polylepis polylepis]]
-	[[Category: Brown, L R.]]	+	[[Category: Brown, L R]]
-	[[Category: Wuthrich, K.]]	+	[[Category: Wuthrich, K]]
	[[Category: Neurotoxin]]		[[Category: Neurotoxin]]

OCA at 13:24, 28 September 2014

2014-09-28T13:24:30Z

←Older revision		Revision as of 13:24, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1ntx.~~png\|left~~\|200px]]	+	==SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS==
		+	<StructureSection load='1ntx' size='340' side='right' caption='[[1ntx]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NTX FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [http://www.ebi.ac.uk/pdbsum/1ntx PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nt/1ntx_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Sequence-specific assignments are presented for the polypeptide backbone protons and a majority of the amino-acid-side-chain protons of alpha-neurotoxin from Dendroaspis polylepis polylepis, and individual amide proton-exchange rates with the solvent are reported. The secondary structure and the hydrogen-bonding patterns in the regular secondary structure elements are deduced from nuclear Overhauser effects and the sequence locations of the slowly exchanging amide protons. The molecule includes a three-stranded antiparallel beta-sheet, and there are indications that two additional short chain segments are arranged in an antiparallel beta-sheet. These structural elements are similar, but not identical, to either the secondary structure reported for erabutoxin b in single crystals, or the solution structure of cytotoxin CTXIIb from Naja mossambica mossambica.

-	~~{{STRUCTURE_1ntx\| PDB=1ntx \| SCENE= }}~~	+	Secondary structure determination for alpha-neurotoxin from Dendroaspis polylepis polylepis based on sequence-specific 1H-nuclear-magnetic-resonance assignments.,Labhardt AM, Hunziker-Kwik EH, Wuthrich K Eur J Biochem. 1988 Nov 1;177(2):295-305. PMID:2847926<ref>PMID:2847926</ref>

-	~~===SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_2847926}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1ntx]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:002847926<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Dendroaspis polylepis polylepis]]		[[Category: Dendroaspis polylepis polylepis]]
	[[Category: Brown, L R.]]		[[Category: Brown, L R.]]
	[[Category: Wuthrich, K.]]		[[Category: Wuthrich, K.]]
	[[Category: Neurotoxin]]		[[Category: Neurotoxin]]

OCA: Protected "1ntx" [edit=sysop:move=sysop]

2012-12-05T20:10:34Z

Protected "1ntx" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:10, 5 December 2012

OCA at 20:10, 5 December 2012

2012-12-05T20:10:32Z

←Older revision		Revision as of 20:10, 5 December 2012
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-	{{Seed}}
	[[Image:1ntx.png\|left\|200px]]		[[Image:1ntx.png\|left\|200px]]

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	{{STRUCTURE_1ntx\| PDB=1ntx \| SCENE= }}		{{STRUCTURE_1ntx\| PDB=1ntx \| SCENE= }}

	===SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS===		===SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_2847926}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 2847926 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_2847926}}		{{ABSTRACT_PUBMED_2847926}}

	==About this Structure==		==About this Structure==
-	~~1NTX~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA].	+	[[1ntx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~2847926~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:002847926</ref><references group="xtra"/>
	[[Category: Dendroaspis polylepis polylepis]]		[[Category: Dendroaspis polylepis polylepis]]
	[[Category: Brown, L R.]]		[[Category: Brown, L R.]]
	[[Category: Wuthrich, K.]]		[[Category: Wuthrich, K.]]
	[[Category: Neurotoxin]]		[[Category: Neurotoxin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:07:36 2009''