1ona - Revision history

OCA at 06:31, 9 August 2023

2023-08-09T06:31:30Z

←Older revision		Revision as of 06:31, 9 August 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ONA FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ONA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:~~MANGANESE+(II)+ION~~'>MN</scene>, <scene name='pdbligand=~~MAN~~:~~ALPHA~~-D-MANNOSE'>~~MAN~~</scene>, <scene name='pdbligand=~~MMA~~:~~O1-METHYL-MANNOSE~~'>~~MMA~~</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.35Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ona FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ona OCA], [https://pdbe.org/1ona PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ona RCSB], [https://www.ebi.ac.uk/pdbsum/1ona PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ona ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ona FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ona OCA], [https://pdbe.org/1ona PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ona RCSB], [https://www.ebi.ac.uk/pdbsum/1ona PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ona ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CONA_CANEN CONA_CANEN]] D-mannose specific lectin.	+	[https://www.uniprot.org/uniprot/CONA_CANEN CONA_CANEN] D-mannose specific lectin.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 38:
	[[Category: Canavalia ensiformis]]		[[Category: Canavalia ensiformis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bouckaert, J]]	+	[[Category: Bouckaert J]]
-	[[Category: Loris, R]]	+	[[Category: Loris R]]
-	[[Category: Maes, D]]	+	[[Category: Maes D]]
-	[[Category: Poortmans, F]]	+	[[Category: Poortmans F]]
-	[[Category: Wyns, L]]	+	[[Category: Wyns L]]
-	~~[[Category: Glycoprotein]]~~	+
-	~~[[Category: Manganese]]~~	+
-	~~[[Category: Plant lectin~~]]	+

OCA at 16:14, 27 October 2021

2021-10-27T16:14:09Z

←Older revision		Revision as of 16:14, 27 October 2021
Line 3:		Line 3:
	<StructureSection load='1ona' size='340' side='right'caption='[[1ona]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='1ona' size='340' side='right'caption='[[1ona]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ONA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ONA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=~~MAN~~:~~ALPHA-D-MANNOSE~~'>~~MAN~~</scene>, <scene name='pdbligand=~~MMA~~:O1-~~METHYL~~-MANNOSE'>~~MMA~~</scene>, <scene name='pdbligand=MN:~~MANGANESE+(II)+ION~~'>MN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ona FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ona OCA], [~~http~~://pdbe.org/1ona PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ona RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ona PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ona ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ona FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ona OCA], [https://pdbe.org/1ona PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ona RCSB], [https://www.ebi.ac.uk/pdbsum/1ona PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ona ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CONA_CANEN CONA_CANEN]] D-mannose specific lectin.	+	[[https://www.uniprot.org/uniprot/CONA_CANEN CONA_CANEN]] D-mannose specific lectin.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 17:30, 22 January 2020

2020-01-22T17:30:18Z

←Older revision		Revision as of 17:30, 22 January 2020
Line 1:		Line 1:

	==CO-CRYSTALS OF CONCANAVALIN A WITH METHYL-3,6-DI-O-(ALPHA-D-MANNOPYRANOSYL)-ALPHA-D-MANNOPYRANOSIDE==		==CO-CRYSTALS OF CONCANAVALIN A WITH METHYL-3,6-DI-O-(ALPHA-D-MANNOPYRANOSYL)-ALPHA-D-MANNOPYRANOSIDE==
-	<StructureSection load='1ona' size='340' side='right' caption='[[1ona]], [[Resolution\|resolution]] 2.35Å' scene=''>	+	<StructureSection load='1ona' size='340' side='right'caption='[[1ona]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONA FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONA FirstGlance]. <br>
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Concanavalin A\|Concanavalin A]]	+	*[[Concanavalin 3D structures\|Concanavalin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Canavalia ensiformis]]		[[Category: Canavalia ensiformis]]
		+	[[Category: Large Structures]]
	[[Category: Bouckaert, J]]		[[Category: Bouckaert, J]]
	[[Category: Loris, R]]		[[Category: Loris, R]]

OCA at 06:00, 18 April 2018

2018-04-18T06:00:46Z

←Older revision		Revision as of 06:00, 18 April 2018
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1ona" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1ona" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Concanavalin A\|Concanavalin A]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:39, 15 February 2018

2018-02-15T07:39:20Z

←Older revision		Revision as of 07:39, 15 February 2018
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONA FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:~~MANGANESE+(II)+ION~~'>MN</scene>, <scene name='pdbligand=~~MAN~~:~~ALPHA~~-D-MANNOSE'>~~MAN~~</scene>, <scene name='pdbligand=~~MMA~~:~~O1-METHYL-MANNOSE~~'>~~MMA~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ona FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ona OCA], [http://pdbe.org/1ona PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ona RCSB], [http://www.ebi.ac.uk/pdbsum/1ona PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ona FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ona OCA], [http://pdbe.org/1ona PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ona RCSB], [http://www.ebi.ac.uk/pdbsum/1ona PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ona ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/1ona_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/1ona_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1ona" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1ona" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Concanavalin A\|Concanavalin A]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 19:07, 20 February 2016

2016-02-20T19:07:05Z

←Older revision		Revision as of 19:07, 20 February 2016
Line 1:		Line 1:
		+
	==CO-CRYSTALS OF CONCANAVALIN A WITH METHYL-3,6-DI-O-(ALPHA-D-MANNOPYRANOSYL)-ALPHA-D-MANNOPYRANOSIDE==		==CO-CRYSTALS OF CONCANAVALIN A WITH METHYL-3,6-DI-O-(ALPHA-D-MANNOPYRANOSYL)-ALPHA-D-MANNOPYRANOSIDE==
	<StructureSection load='1ona' size='340' side='right' caption='[[1ona]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='1ona' size='340' side='right' caption='[[1ona]], [[Resolution\|resolution]] 2.35Å' scene=''>

OCA at 16:40, 8 February 2016

2016-02-08T16:40:22Z

←Older revision		Revision as of 16:40, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ona ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 13:29, 10 September 2015

2015-09-10T13:29:31Z

←Older revision		Revision as of 13:29, 10 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONA FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ona FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ona OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ona RCSB], [http://www.ebi.ac.uk/pdbsum/1ona PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ona FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ona OCA], [http://pdbe.org/1ona PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ona RCSB], [http://www.ebi.ac.uk/pdbsum/1ona PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ona" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 00:44, 25 December 2014

2014-12-25T00:44:05Z

←Older revision		Revision as of 00:44, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONA FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONA FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ona FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ona OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ona RCSB], [http://www.ebi.ac.uk/pdbsum/1ona PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ona FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ona OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ona RCSB], [http://www.ebi.ac.uk/pdbsum/1ona PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CONA_CANEN CONA_CANEN]] D-mannose specific lectin.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Canavalia ensiformis]]		[[Category: Canavalia ensiformis]]
-	[[Category: Bouckaert, J.]]	+	[[Category: Bouckaert, J]]
-	[[Category: Loris, R.]]	+	[[Category: Loris, R]]
-	[[Category: Maes, D.]]	+	[[Category: Maes, D]]
-	[[Category: Poortmans, F.]]	+	[[Category: Poortmans, F]]
-	[[Category: Wyns, L.]]	+	[[Category: Wyns, L]]
	[[Category: Glycoprotein]]		[[Category: Glycoprotein]]
	[[Category: Manganese]]		[[Category: Manganese]]
	[[Category: Plant lectin]]		[[Category: Plant lectin]]

OCA at 15:33, 28 September 2014

2014-09-28T15:33:29Z

←Older revision		Revision as of 15:33, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1ona.~~png\|left~~\|200px]]	+	==CO-CRYSTALS OF CONCANAVALIN A WITH METHYL-3,6-DI-O-(ALPHA-D-MANNOPYRANOSYL)-ALPHA-D-MANNOPYRANOSIDE==
		+	<StructureSection load='1ona' size='340' side='right' caption='[[1ona]], [[Resolution\|resolution]] 2.35Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ona]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONA FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ona FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ona OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ona RCSB], [http://www.ebi.ac.uk/pdbsum/1ona PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/1ona_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The structure of concanavalin A in complex with the trimannoside methyl-3,6-di-O-(alpha-D-mannopyranosyl)-alpha-D-mannopyranoside has been determined in a novel space group. In three of the four subunits of the concanavalin A tetramer, the interactions between the protein and the bound saccharide are essentially identical to those reported previously by other authors (Naismith, J. H., and Field, R. A. (1996) J. Biol. Chem. 271, 972-976). In the fourth subunit, however, the alpha1-->3 linkage has a different conformation, resulting in a different part of the alpha1-->3-linked mannose interacting with essentially the same surface of the protein. Furthermore, significant differences are observed in the quaternary associations of the subunits compared with the saccharide-free structures and other carbohydrate complexes, suggesting that the concanavalin A tetramer is a rather flexible entity.

-	~~{{STRUCTURE_1ona\| PDB=1ona \| SCENE= }}~~	+	A structure of the complex between concanavalin A and methyl-3,6-di-O-(alpha-D-mannopyranosyl)-alpha-D-mannopyranoside reveals two binding modes.,Loris R, Maes D, Poortmans F, Wyns L, Bouckaert J J Biol Chem. 1996 Nov 29;271(48):30614-8. PMID:8940035<ref>PMID:8940035</ref>

-	~~===CO-CRYSTALS OF CONCANAVALIN A WITH METHYL-3~~,~~6-DI-O-(ALPHA-D-MANNOPYRANOSYL)-ALPHA-D-MANNOPYRANOSIDE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_8940035}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1ona]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Canavalia_ensiformis Canavalia ensiformis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1ONA OCA].~~	+

	==See Also==		==See Also==
	*[[Concanavalin A\|Concanavalin A]]		*[[Concanavalin A\|Concanavalin A]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:008940035<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Canavalia ensiformis]]		[[Category: Canavalia ensiformis]]
	[[Category: Bouckaert, J.]]		[[Category: Bouckaert, J.]]