1po3 - Revision history

OCA at 09:45, 16 August 2023

2023-08-16T09:45:44Z

←Older revision		Revision as of 09:45, 16 August 2023
Line 3:		Line 3:
	<StructureSection load='1po3' size='340' side='right'caption='[[1po3]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='1po3' size='340' side='right'caption='[[1po3]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1po3]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1PO3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1po3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PO3 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>~~, ~~<scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.4Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1pnz\|1pnz]], [[1po0\|1po0]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">FECA OR B4291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1po3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1po3 OCA], [https://pdbe.org/1po3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1po3 RCSB], [https://www.ebi.ac.uk/pdbsum/1po3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1po3 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1po3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1po3 OCA], [~~http~~://pdbe.org/1po3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1po3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1po3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1po3 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/FECA_ECOLI FECA_ECOLI]] FecA is the outer membrane receptor protein in the Fe(3+) dicitrate transport system.	+	[https://www.uniprot.org/uniprot/FECA_ECOLI FECA_ECOLI] FecA is the outer membrane receptor protein in the Fe(3+) dicitrate transport system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Buchanan~~, S K~~]]	+	[[Category: Buchanan SK]]
-	[[Category: Grizot, S]]	+	[[Category: Grizot S]]
-	[[Category: Yue~~, W W]]~~	+	[[Category: Yue WW]]
-	~~[[Category: Beta barrel]]~~	+
-	~~[[Category: Citrate]]~~	+
-	~~[[Category: Iron]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Outer membrane protein]]~~	+
-	~~[[Category: Siderophore]]~~	+
-	~~[[Category: Tonb-dependent transport~~]]	+

OCA at 07:32, 9 December 2020

2020-12-09T07:32:58Z

←Older revision		Revision as of 07:32, 9 December 2020
Line 1:		Line 1:

	==Crystal structure of ferric citrate transporter FecA in complex with ferric citrate==		==Crystal structure of ferric citrate transporter FecA in complex with ferric citrate==
-	<StructureSection load='1po3' size='340' side='right' caption='[[1po3]], [[Resolution\|resolution]] 3.40Å' scene=''>	+	<StructureSection load='1po3' size='340' side='right'caption='[[1po3]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1po3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1PO3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1po3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1PO3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pnz\|1pnz]], [[1po0\|1po0]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1pnz\|1pnz]], [[1po0\|1po0]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FECA OR B4291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FECA OR B4291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1po3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1po3 OCA], [http://pdbe.org/1po3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1po3 RCSB], [http://www.ebi.ac.uk/pdbsum/1po3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1po3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1po3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1po3 OCA], [http://pdbe.org/1po3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1po3 RCSB], [http://www.ebi.ac.uk/pdbsum/1po3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1po3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Buchanan, S K]]		[[Category: Buchanan, S K]]
	[[Category: Grizot, S]]		[[Category: Grizot, S]]

OCA at 08:11, 24 February 2018

2018-02-24T08:11:02Z

←Older revision		Revision as of 08:11, 24 February 2018
Line 1:		Line 1:
		+
	==Crystal structure of ferric citrate transporter FecA in complex with ferric citrate==		==Crystal structure of ferric citrate transporter FecA in complex with ferric citrate==
	<StructureSection load='1po3' size='340' side='right' caption='[[1po3]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='1po3' size='340' side='right' caption='[[1po3]], [[Resolution\|resolution]] 3.40Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pnz\|1pnz]], [[1po0\|1po0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pnz\|1pnz]], [[1po0\|1po0]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FECA OR B4291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FECA OR B4291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1po3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1po3 OCA], [http://pdbe.org/1po3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1po3 RCSB], [http://www.ebi.ac.uk/pdbsum/1po3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1po3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1po3 OCA], [http://pdbe.org/1po3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1po3 RCSB], [http://www.ebi.ac.uk/pdbsum/1po3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1po3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/1po3_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/1po3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 09:01, 7 February 2016

2016-02-07T09:01:31Z

←Older revision		Revision as of 09:01, 7 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1po3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:53, 9 September 2015

2015-09-09T23:53:03Z

←Older revision		Revision as of 23:53, 9 September 2015
Line 2:		Line 2:
	<StructureSection load='1po3' size='340' side='right' caption='[[1po3]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='1po3' size='340' side='right' caption='[[1po3]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1po3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PO3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1po3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PO3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pnz\|1pnz]], [[1po0\|1po0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pnz\|1pnz]], [[1po0\|1po0]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FECA OR B4291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FECA OR B4291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1po3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1po3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1po3 RCSB], [http://www.ebi.ac.uk/pdbsum/1po3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1po3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1po3 OCA], [http://pdbe.org/1po3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1po3 RCSB], [http://www.ebi.ac.uk/pdbsum/1po3 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1po3" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Buchanan, S K]]		[[Category: Buchanan, S K]]
	[[Category: Grizot, S]]		[[Category: Grizot, S]]

OCA at 13:52, 24 December 2014

2014-12-24T13:52:51Z

←Older revision		Revision as of 13:52, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1po3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PO3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1po3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PO3 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pnz\|1pnz]], [[1po0\|1po0]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pnz\|1pnz]], [[1po0\|1po0]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FECA OR B4291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FECA OR B4291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1po3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1po3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1po3 RCSB], [http://www.ebi.ac.uk/pdbsum/1po3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1po3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1po3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1po3 RCSB], [http://www.ebi.ac.uk/pdbsum/1po3 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FECA_ECOLI FECA_ECOLI]] FecA is the outer membrane receptor protein in the Fe(3+) dicitrate transport system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Buchanan, S K.]]	+	[[Category: Buchanan, S K]]
-	[[Category: Grizot, S.]]	+	[[Category: Grizot, S]]
-	[[Category: Yue, W W.]]	+	[[Category: Yue, W W]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Citrate]]		[[Category: Citrate]]

OCA at 21:49, 28 September 2014

2014-09-28T21:49:45Z

←Older revision		Revision as of 21:49, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1po3.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of ferric citrate transporter FecA in complex with ferric citrate==
		+	<StructureSection load='1po3' size='340' side='right' caption='[[1po3]], [[Resolution\|resolution]] 3.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1po3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PO3 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pnz\|1pnz]], [[1po0\|1po0]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FECA OR B4291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1po3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1po3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1po3 RCSB], [http://www.ebi.ac.uk/pdbsum/1po3 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/1po3_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Escherichia coli possesses a TonB-dependent transport system, which exploits the iron-binding capacity of citrate and its natural abundance. Here, we describe three structures of the outer membrane ferric citrate transporter FecA: unliganded and complexed with iron-free or diferric dicitrate. We show the structural mechanism for discrimination between the iron-free and ferric siderophore: the binding of diferric dicitrate, but not iron-free dicitrate alone, causes major conformational rearrangements in the transporter. The structure of FecA bound with iron-free dicitrate represents the first structure of a TonB-dependent transporter bound with an iron-free siderophore. Binding of diferric dicitrate to FecA results in changes in the orientation of the two citrate ions relative to each other and in their interactions with FecA, compared to the binding of iron-free dicitrate. The changes in ligand binding are accompanied by conformational changes in three areas of FecA: two extracellular loops, one plug domain loop and the periplasmic TonB-box motif. The positional and conformational changes in the siderophore and transporter initiate two independent events: ferric citrate transport into the periplasm and transcription induction of the fecABCDE transport genes. From these data, we propose a two-step ligand recognition event: FecA binds iron-free dicitrate in the non-productive state or first step, followed by siderophore displacement to form the transport-competent, diferric dicitrate-bound state in the second step.

-	~~{{STRUCTURE_1po3\| PDB=1po3 \| SCENE= }}~~	+	Structural evidence for iron-free citrate and ferric citrate binding to the TonB-dependent outer membrane transporter FecA.,Yue WW, Grizot S, Buchanan SK J Mol Biol. 2003 Sep 12;332(2):353-68. PMID:12948487<ref>PMID:12948487</ref>

-	~~===Crystal structure~~ of ~~ferric citrate transporter FecA in complex with ferric citrate===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12948487}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1po3]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:012948487<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Buchanan, S K.]]		[[Category: Buchanan, S K.]]

OCA: Protected "1po3" [edit=sysop:move=sysop]

2012-12-19T12:13:44Z

Protected "1po3" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:13, 19 December 2012

OCA at 12:13, 19 December 2012

2012-12-19T12:13:40Z

←Older revision		Revision as of 12:13, 19 December 2012
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-	{{Seed}}
	[[Image:1po3.png\|left\|200px]]		[[Image:1po3.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1po3\| PDB=1po3 \| SCENE= }}		{{STRUCTURE_1po3\| PDB=1po3 \| SCENE= }}

	===Crystal structure of ferric citrate transporter FecA in complex with ferric citrate===		===Crystal structure of ferric citrate transporter FecA in complex with ferric citrate===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_12948487}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 12948487 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_12948487}}		{{ABSTRACT_PUBMED_12948487}}

	==About this Structure==		==About this Structure==
-	~~1PO3~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA].	+	[[1po3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12948487~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012948487</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Buchanan, S K.]]		[[Category: Buchanan, S K.]]
Line 31:		Line 19:
	[[Category: Citrate]]		[[Category: Citrate]]
	[[Category: Iron]]		[[Category: Iron]]
		+	[[Category: Membrane protein]]
	[[Category: Outer membrane protein]]		[[Category: Outer membrane protein]]
	[[Category: Siderophore]]		[[Category: Siderophore]]
	[[Category: Tonb-dependent transport]]		[[Category: Tonb-dependent transport]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:45:16 2009''

OCA at 10:45, 16 February 2009

2009-02-16T10:45:17Z

←Older revision		Revision as of 10:45, 16 February 2009
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	==About this Structure==		==About this Structure==
-	1PO3 is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA].	+	1PO3 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PO3 OCA].

	==Reference==		==Reference==
-	~~Structural evidence for iron-free citrate and ferric citrate binding to the TonB-dependent outer membrane transporter FecA., Yue WW, Grizot S, Buchanan SK, J Mol Biol. 2003 Sep 12;332(2):353-68.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/12948487 12948487]~~	+	<ref group="xtra">PMID:12948487</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Single protein]]
	[[Category: Buchanan, S K.]]		[[Category: Buchanan, S K.]]
	[[Category: Grizot, S.]]		[[Category: Grizot, S.]]
Line 36:		Line 35:
	[[Category: Tonb-dependent transport]]		[[Category: Tonb-dependent transport]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Jul 27 15~~:02:~~26 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:45:16 2009''