1qac - Revision history

OCA at 10:00, 16 August 2023

2023-08-16T10:00:57Z

←Older revision		Revision as of 10:00, 16 August 2023
Line 3:		Line 3:
	<StructureSection load='1qac' size='340' side='right'caption='[[1qac]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1qac' size='340' side='right'caption='[[1qac]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QAC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QAC FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qac OCA], [https://pdbe.org/1qac PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qac RCSB], [https://www.ebi.ac.uk/pdbsum/1qac PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qac ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qac OCA], [https://pdbe.org/1qac PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qac RCSB], [https://www.ebi.ac.uk/pdbsum/1qac PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qac ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/KV401_HUMAN KV401_HUMAN] V segment of the variable domain of immunoglobulins light chain that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).<ref>PMID:17576170</ref> <ref>PMID:20176268</ref> <ref>PMID:22158414</ref> <ref>PMID:24600447</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Cai, X]]	+	[[Category: Cai X]]
-	[[Category: Johnson, G]]	+	[[Category: Johnson G]]
-	[[Category: Pokkuluri~~, P R~~]]	+	[[Category: Pokkuluri PR]]
-	[[Category: Schiffer, M]]	+	[[Category: Schiffer M]]
-	[[Category: Stevens~~, F J]]~~	+	[[Category: Stevens FJ]]
-	~~[[Category: Beta barrel immunoglobulin vl domain dimer]]~~	+
-	~~[[Category: Flipped domain dimer]]~~	+
-	~~[[Category: Immune system~~]]	+

OCA at 09:39, 8 September 2021

2021-09-08T09:39:43Z

←Older revision		Revision as of 09:39, 8 September 2021
Line 3:		Line 3:
	<StructureSection load='1qac' size='340' side='right'caption='[[1qac]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1qac' size='340' side='right'caption='[[1qac]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1QAC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QAC FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1qac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qac OCA], [~~http~~://pdbe.org/1qac PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1qac RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1qac PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1qac ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qac OCA], [https://pdbe.org/1qac PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qac RCSB], [https://www.ebi.ac.uk/pdbsum/1qac PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qac ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 10:07, 27 November 2019

2019-11-27T10:07:57Z

←Older revision		Revision as of 10:07, 27 November 2019
Line 1:		Line 1:

	==CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE==		==CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE==
-	<StructureSection load='1qac' size='340' side='right' caption='[[1qac]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='1qac' size='340' side='right'caption='[[1qac]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QAC FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QAC FirstGlance]. <br>
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Cai, X]]		[[Category: Cai, X]]
	[[Category: Johnson, G]]		[[Category: Johnson, G]]

OCA at 08:08, 24 February 2018

2018-02-24T08:08:52Z

←Older revision		Revision as of 08:08, 24 February 2018
Line 1:		Line 1:
		+
	==CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE==		==CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE==
	<StructureSection load='1qac' size='340' side='right' caption='[[1qac]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1qac' size='340' side='right' caption='[[1qac]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QAC FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QAC FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qac OCA], [http://pdbe.org/1qac PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qac RCSB], [http://www.ebi.ac.uk/pdbsum/1qac PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qac OCA], [http://pdbe.org/1qac PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qac RCSB], [http://www.ebi.ac.uk/pdbsum/1qac PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qac ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 9:		Line 10:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qa/1qac_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qa/1qac_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 02:49, 9 February 2016

2016-02-09T02:49:12Z

←Older revision		Revision as of 02:49, 9 February 2016
Line 13:		Line 13:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qac ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:52, 10 September 2015

2015-09-10T17:52:23Z

←Older revision		Revision as of 17:52, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1qac' size='340' side='right' caption='[[1qac]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1qac' size='340' side='right' caption='[[1qac]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QAC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QAC FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qac OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qac RCSB], [http://www.ebi.ac.uk/pdbsum/1qac PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qac OCA], [http://pdbe.org/1qac PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qac RCSB], [http://www.ebi.ac.uk/pdbsum/1qac PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1qac" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Cai, X]]		[[Category: Cai, X]]
	[[Category: Johnson, G]]		[[Category: Johnson, G]]

OCA at 07:04, 6 January 2015

2015-01-06T07:04:01Z

←Older revision		Revision as of 07:04, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QAC FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QAC FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qac OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qac RCSB], [http://www.ebi.ac.uk/pdbsum/1qac PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qac OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qac RCSB], [http://www.ebi.ac.uk/pdbsum/1qac PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Cai, X.]]	+	[[Category: Cai, X]]
-	[[Category: Johnson, G.]]	+	[[Category: Johnson, G]]
-	[[Category: Pokkuluri, P R.]]	+	[[Category: Pokkuluri, P R]]
-	[[Category: Schiffer, M.]]	+	[[Category: Schiffer, M]]
-	[[Category: Stevens, F J.]]	+	[[Category: Stevens, F J]]
	[[Category: Beta barrel immunoglobulin vl domain dimer]]		[[Category: Beta barrel immunoglobulin vl domain dimer]]
	[[Category: Flipped domain dimer]]		[[Category: Flipped domain dimer]]
	[[Category: Immune system]]		[[Category: Immune system]]

OCA at 15:04, 29 September 2014

2014-09-29T15:04:56Z

←Older revision		Revision as of 15:04, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1qac.~~png\|left~~\|200px]]	+	==CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE==
		+	<StructureSection load='1qac' size='340' side='right' caption='[[1qac]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1qac]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QAC FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qac OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qac RCSB], [http://www.ebi.ac.uk/pdbsum/1qac PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qa/1qac_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The importance of unsatisfied hydrogen bonding potential on protein-protein interaction was studied. Two alternate modes of dimerization (conventional and flipped form) of an immunoglobulin light chain variable domain (V(L)) were previously identified. In the flipped form, interface residue Gln89 would have an unsatisfied hydrogen bonding potential. Removal of this Gln should render the flipped dimer as the more favorable quaternary form. High resolution crystallographic studies of the Q89A and Q89L mutants show, as we predicted, that these proteins indeed form flipped dimers with very similar interfaces. A small cavity is present in the Q89A mutant that is reflected in the approximately 100 times lower association constant than found for the Q89L mutant. The association constant of Q89A and Q89L proteins (4 x 10(6) M(-1) and >10(8) M(-1)) are 10- and 1,000-fold higher than that of the wild-type protein that forms conventional dimers clearly showing the energetic reasons for the flipped dimer formation.

-	~~{{STRUCTURE_1qac\| PDB=1qac \| SCENE= }}~~	+	Change in dimerization mode by removal of a single unsatisfied polar residue located at the interface.,Pokkuluri PR, Cai X, Johnson G, Stevens FJ, Schiffer M Protein Sci. 2000 Sep;9(9):1852-5. PMID:11045631<ref>PMID:11045631</ref>

-	~~===CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11045631}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1qac]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011045631<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Cai, X.]]		[[Category: Cai, X.]]

OCA: Protected "1qac" [edit=sysop:move=sysop]

2013-01-02T10:10:04Z

Protected "1qac" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:10, 2 January 2013

OCA at 10:10, 2 January 2013

2013-01-02T10:10:00Z

←Older revision		Revision as of 10:10, 2 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1qac.png\|left\|200px]]		[[Image:1qac.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1qac", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1qac\| PDB=1qac \| SCENE= }}		{{STRUCTURE_1qac\| PDB=1qac \| SCENE= }}

	===CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE===		===CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE===

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	{{ABSTRACT_PUBMED_11045631}}		{{ABSTRACT_PUBMED_11045631}}

	==About this Structure==		==About this Structure==
-	~~1QAC~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA].	+	[[1qac]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAC OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11045631~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011045631</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Cai, X.]]		[[Category: Cai, X.]]
Line 32:		Line 20:
	[[Category: Beta barrel immunoglobulin vl domain dimer]]		[[Category: Beta barrel immunoglobulin vl domain dimer]]
	[[Category: Flipped domain dimer]]		[[Category: Flipped domain dimer]]
-		+	[[Category: Immune system]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 05:51:28 2009''~~	+