1qf3 - Revision history

OCA at 06:11, 3 April 2024

2024-04-03T06:11:51Z

←Older revision		Revision as of 06:11, 3 April 2024
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qf3 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qf3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The crystal structures of complexes of peanut lectin with methyl-beta-galactose and N-acetyllactosamine have been determined at 2.8 and 2.7 A, respectively. These, and the complexes involving lactose and the T-antigenic disaccharide reported previously, permit a detailed characterization of peanut-lectin-carbohydrate association and the role of water molecules therein. The water molecules in the combining site are substantially conserved in the four complexes. The role of interacting sugar hydroxyl groups, when absent, are often mimicked by ordered water molecules not only at the primary combining site, but also at the site of the second sugar ring. The similarity of peanut-lectin-sugar interactions with those in other galactose/N-acetylgalactosamine-specific lectins also extend to a substantial degree to water bridges. The comparative study provides a structural explanation for the exclusive specificity of peanut lectin for galactose at the monosaccharide level, compared with that of the other lectins for galactose as well as N-acetylgalactosamine. The complexes also provide a qualitative structural rationale for differences in the strengths of binding of peanut lectin to different sugars.
-
-	Structures of the complexes of peanut lectin with methyl-beta-galactose and N-acetyllactosamine and a comparative study of carbohydrate binding in Gal/GalNAc-specific legume lectins.,Ravishankar R, Suguna K, Surolia A, Vijayan M Acta Crystallogr D Biol Crystallogr. 1999 Aug;55(Pt 8):1375-82. PMID:10417405<ref>PMID:10417405</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1qf3" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Agglutinin 3D structures\|Agglutinin 3D structures]]		*[[Agglutinin 3D structures\|Agglutinin 3D structures]]
	*[[Galactose-binding lectin\|Galactose-binding lectin]]		*[[Galactose-binding lectin\|Galactose-binding lectin]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 23:47, 27 December 2023

2023-12-27T23:47:20Z

←Older revision		Revision as of 23:47, 27 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf3 OCA], [https://pdbe.org/1qf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qf3 RCSB], [https://www.ebi.ac.uk/pdbsum/1qf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qf3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf3 OCA], [https://pdbe.org/1qf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qf3 RCSB], [https://www.ebi.ac.uk/pdbsum/1qf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qf3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/LECG_ARAHY LECG_ARAHY]] D-galactose specific lectin.	+	[https://www.uniprot.org/uniprot/LECG_ARAHY LECG_ARAHY] D-galactose specific lectin.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 38:		Line 39:
	[[Category: Arachis hypogaea]]		[[Category: Arachis hypogaea]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ravishankar, R]]	+	[[Category: Ravishankar R]]
-	[[Category: Suguna, K]]	+	[[Category: Suguna K]]
-	[[Category: Surolia, A]]	+	[[Category: Surolia A]]
-	[[Category: Vijayan, M]]	+	[[Category: Vijayan M]]
-	~~[[Category: Carbohydrate specificity]]~~	+
-	~~[[Category: Lectin]]~~	+
-	~~[[Category: Legume lectin]]~~	+
-	~~[[Category: Methyl-beta- galactose]]~~	+
-	~~[[Category: Sugar binding protein]]~~	+
-	~~[[Category: Water bridge~~]]	+

OCA at 09:55, 15 September 2021

2021-09-15T09:55:16Z

←Older revision		Revision as of 09:55, 15 September 2021
Line 3:		Line 3:
	<StructureSection load='1qf3' size='340' side='right'caption='[[1qf3]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='1qf3' size='340' side='right'caption='[[1qf3]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1qf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf3 OCA], [~~http~~://pdbe.org/1qf3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1qf3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1qf3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1qf3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf3 OCA], [https://pdbe.org/1qf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qf3 RCSB], [https://www.ebi.ac.uk/pdbsum/1qf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qf3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/LECG_ARAHY LECG_ARAHY]] D-galactose specific lectin.	+	[[https://www.uniprot.org/uniprot/LECG_ARAHY LECG_ARAHY]] D-galactose specific lectin.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:11, 27 November 2019

2019-11-27T07:11:05Z

←Older revision		Revision as of 07:11, 27 November 2019
Line 1:		Line 1:

	==PEANUT LECTIN COMPLEXED WITH METHYL-BETA-GALACTOSE==		==PEANUT LECTIN COMPLEXED WITH METHYL-BETA-GALACTOSE==
-	<StructureSection load='1qf3' size='340' side='right' caption='[[1qf3]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='1qf3' size='340' side='right'caption='[[1qf3]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1qf3" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1qf3" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Agglutinin 3D structures\|Agglutinin 3D structures]]
		+	*[[Galactose-binding lectin\|Galactose-binding lectin]]
	== References ==		== References ==
	<references/>		<references/>
Line 33:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Arachis hypogaea]]		[[Category: Arachis hypogaea]]
		+	[[Category: Large Structures]]
	[[Category: Ravishankar, R]]		[[Category: Ravishankar, R]]
	[[Category: Suguna, K]]		[[Category: Suguna, K]]

OCA at 07:56, 24 February 2018

2018-02-24T07:56:18Z

←Older revision		Revision as of 07:56, 24 February 2018
Line 1:		Line 1:
		+
	==PEANUT LECTIN COMPLEXED WITH METHYL-BETA-GALACTOSE==		==PEANUT LECTIN COMPLEXED WITH METHYL-BETA-GALACTOSE==
	<StructureSection load='1qf3' size='340' side='right' caption='[[1qf3]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='1qf3' size='340' side='right' caption='[[1qf3]], [[Resolution\|resolution]] 2.80Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf3 OCA], [http://pdbe.org/1qf3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qf3 RCSB], [http://www.ebi.ac.uk/pdbsum/1qf3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf3 OCA], [http://pdbe.org/1qf3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qf3 RCSB], [http://www.ebi.ac.uk/pdbsum/1qf3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qf3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qf/1qf3_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qf/1qf3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1qf3" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1qf3" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Galactose-binding lectin\|Galactose-binding lectin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 21:44, 9 February 2016

2016-02-09T21:44:07Z

←Older revision		Revision as of 21:44, 9 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qf3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 02:19, 11 September 2015

2015-09-11T02:19:19Z

←Older revision		Revision as of 02:19, 11 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qf3 RCSB], [http://www.ebi.ac.uk/pdbsum/1qf3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf3 OCA], [http://pdbe.org/1qf3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qf3 RCSB], [http://www.ebi.ac.uk/pdbsum/1qf3 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1qf3" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 09:44, 25 December 2014

2014-12-25T09:44:07Z

←Older revision		Revision as of 09:44, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qf3 RCSB], [http://www.ebi.ac.uk/pdbsum/1qf3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qf3 RCSB], [http://www.ebi.ac.uk/pdbsum/1qf3 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LECG_ARAHY LECG_ARAHY]] D-galactose specific lectin.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Arachis hypogaea]]		[[Category: Arachis hypogaea]]
-	[[Category: Ravishankar, R.]]	+	[[Category: Ravishankar, R]]
-	[[Category: Suguna, K.]]	+	[[Category: Suguna, K]]
-	[[Category: Surolia, A.]]	+	[[Category: Surolia, A]]
-	[[Category: Vijayan, M.]]	+	[[Category: Vijayan, M]]
	[[Category: Carbohydrate specificity]]		[[Category: Carbohydrate specificity]]
	[[Category: Lectin]]		[[Category: Lectin]]

OCA at 16:20, 29 September 2014

2014-09-29T16:20:16Z

←Older revision		Revision as of 16:20, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1qf3.~~png\|left~~\|200px]]	+	==PEANUT LECTIN COMPLEXED WITH METHYL-BETA-GALACTOSE==
		+	<StructureSection load='1qf3' size='340' side='right' caption='[[1qf3]], [[Resolution\|resolution]] 2.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1qf3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QF3 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qf3 RCSB], [http://www.ebi.ac.uk/pdbsum/1qf3 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qf/1qf3_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structures of complexes of peanut lectin with methyl-beta-galactose and N-acetyllactosamine have been determined at 2.8 and 2.7 A, respectively. These, and the complexes involving lactose and the T-antigenic disaccharide reported previously, permit a detailed characterization of peanut-lectin-carbohydrate association and the role of water molecules therein. The water molecules in the combining site are substantially conserved in the four complexes. The role of interacting sugar hydroxyl groups, when absent, are often mimicked by ordered water molecules not only at the primary combining site, but also at the site of the second sugar ring. The similarity of peanut-lectin-sugar interactions with those in other galactose/N-acetylgalactosamine-specific lectins also extend to a substantial degree to water bridges. The comparative study provides a structural explanation for the exclusive specificity of peanut lectin for galactose at the monosaccharide level, compared with that of the other lectins for galactose as well as N-acetylgalactosamine. The complexes also provide a qualitative structural rationale for differences in the strengths of binding of peanut lectin to different sugars.

-	~~{{STRUCTURE_1qf3\| PDB=1qf3 \| SCENE= }}~~	+	Structures of the complexes of peanut lectin with methyl-beta-galactose and N-acetyllactosamine and a comparative study of carbohydrate binding in Gal/GalNAc-specific legume lectins.,Ravishankar R, Suguna K, Surolia A, Vijayan M Acta Crystallogr D Biol Crystallogr. 1999 Aug;55(Pt 8):1375-82. PMID:10417405<ref>PMID:10417405</ref>

-	~~===PEANUT LECTIN COMPLEXED WITH METHYL-BETA-GALACTOSE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_10417405}}~~	+	==See Also==
-		+	*[[Galactose-binding lectin\|Galactose-binding lectin]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1qf3~~]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF3 OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:010417405<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Arachis hypogaea]]		[[Category: Arachis hypogaea]]
	[[Category: Ravishankar, R.]]		[[Category: Ravishankar, R.]]

OCA: Protected "1qf3" [edit=sysop:move=sysop]

2013-01-02T09:51:39Z

Protected "1qf3" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:51, 2 January 2013