1qi7 - Revision history

OCA at 10:04, 16 August 2023

2023-08-16T10:04:01Z

←Older revision		Revision as of 10:04, 16 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qi7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QI7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qi7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QI7 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qi7 OCA], [https://pdbe.org/1qi7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qi7 RCSB], [https://www.ebi.ac.uk/pdbsum/1qi7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qi7 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qi7 OCA], [https://pdbe.org/1qi7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qi7 RCSB], [https://www.ebi.ac.uk/pdbsum/1qi7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qi7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~RIP2_SAPOF RIP2_SAPOF]~~] Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells. Useful as immunotoxin for pharmacological applications.	+	[https://www.uniprot.org/uniprot/RIP6_SAPOF RIP6_SAPOF] Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells. Useful as immunotoxin for pharmacological applications.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Saponaria officinalis]]		[[Category: Saponaria officinalis]]
-	~~[[Category: RRNA N-glycosylase]]~~	+	[[Category: Federici L]]
-	[[Category: Federici, L]]	+	[[Category: Ippoliti R]]
-	[[Category: Ippoliti, R]]	+	[[Category: Lendaro E]]
-	[[Category: Lendaro, E]]	+	[[Category: Savino C]]
-	[[Category: Savino, C]]	+	[[Category: Tsernoglou D]]
-	[[Category: Tsernoglou, D]]	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: N-glycosidase]]~~	+
-	~~[[Category: Ribosome inactivating protein~~]]	+

OCA at 09:57, 15 September 2021

2021-09-15T09:57:39Z

←Older revision		Revision as of 09:57, 15 September 2021
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	<StructureSection load='1qi7' size='340' side='right'caption='[[1qi7]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1qi7' size='340' side='right'caption='[[1qi7]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qi7]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1QI7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qi7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QI7 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1qi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qi7 OCA], [~~http~~://pdbe.org/1qi7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1qi7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1qi7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1qi7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qi7 OCA], [https://pdbe.org/1qi7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qi7 RCSB], [https://www.ebi.ac.uk/pdbsum/1qi7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qi7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RIP2_SAPOF RIP2_SAPOF]] Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells. Useful as immunotoxin for pharmacological applications.	+	[[https://www.uniprot.org/uniprot/RIP2_SAPOF RIP2_SAPOF]] Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells. Useful as immunotoxin for pharmacological applications.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:36, 27 November 2019

2019-11-27T10:36:03Z

←Older revision		Revision as of 10:36, 27 November 2019
Line 1:		Line 1:

	==THE CRYSTAL STRUCTURE AT 2.0 A OF SAPORIN SO6, A RIBOSOME INACTIVATING PROTEIN FROM SAPONARIA OFFICINALIS==		==THE CRYSTAL STRUCTURE AT 2.0 A OF SAPORIN SO6, A RIBOSOME INACTIVATING PROTEIN FROM SAPONARIA OFFICINALIS==
-	<StructureSection load='1qi7' size='340' side='right' caption='[[1qi7]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='1qi7' size='340' side='right'caption='[[1qi7]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qi7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QI7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qi7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QI7 FirstGlance]. <br>
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Saponaria officinalis]]		[[Category: Saponaria officinalis]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]

OCA at 08:33, 24 February 2018

2018-02-24T08:33:52Z

←Older revision		Revision as of 08:33, 24 February 2018
Line 1:		Line 1:
		+
	==THE CRYSTAL STRUCTURE AT 2.0 A OF SAPORIN SO6, A RIBOSOME INACTIVATING PROTEIN FROM SAPONARIA OFFICINALIS==		==THE CRYSTAL STRUCTURE AT 2.0 A OF SAPORIN SO6, A RIBOSOME INACTIVATING PROTEIN FROM SAPONARIA OFFICINALIS==
	<StructureSection load='1qi7' size='340' side='right' caption='[[1qi7]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1qi7' size='340' side='right' caption='[[1qi7]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qi7 OCA], [http://pdbe.org/1qi7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qi7 RCSB], [http://www.ebi.ac.uk/pdbsum/1qi7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qi7 OCA], [http://pdbe.org/1qi7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qi7 RCSB], [http://www.ebi.ac.uk/pdbsum/1qi7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qi7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qi/1qi7_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qi/1qi7_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qi7 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:08, 11 September 2015

2015-09-11T08:08:45Z

←Older revision		Revision as of 08:08, 11 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qi7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qi7 RCSB], [http://www.ebi.ac.uk/pdbsum/1qi7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qi7 OCA], [http://pdbe.org/1qi7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qi7 RCSB], [http://www.ebi.ac.uk/pdbsum/1qi7 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1qi7" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:40, 25 December 2014

2014-12-25T13:40:13Z

←Older revision		Revision as of 13:40, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qi7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QI7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qi7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QI7 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qi7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qi7 RCSB], [http://www.ebi.ac.uk/pdbsum/1qi7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qi7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qi7 RCSB], [http://www.ebi.ac.uk/pdbsum/1qi7 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RIP2_SAPOF RIP2_SAPOF]] Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells. Useful as immunotoxin for pharmacological applications.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	[[Category: Saponaria officinalis]]		[[Category: Saponaria officinalis]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]
-	[[Category: Federici, L.]]	+	[[Category: Federici, L]]
-	[[Category: Ippoliti, R.]]	+	[[Category: Ippoliti, R]]
-	[[Category: Lendaro, E.]]	+	[[Category: Lendaro, E]]
-	[[Category: Savino, C.]]	+	[[Category: Savino, C]]
-	[[Category: Tsernoglou, D.]]	+	[[Category: Tsernoglou, D]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: N-glycosidase]]		[[Category: N-glycosidase]]
	[[Category: Ribosome inactivating protein]]		[[Category: Ribosome inactivating protein]]

OCA at 16:15, 29 September 2014

2014-09-29T16:15:12Z

←Older revision		Revision as of 16:15, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1qi7.~~png\|left~~\|200px]]	+	==THE CRYSTAL STRUCTURE AT 2.0 A OF SAPORIN SO6, A RIBOSOME INACTIVATING PROTEIN FROM SAPONARIA OFFICINALIS==
		+	<StructureSection load='1qi7' size='340' side='right' caption='[[1qi7]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1qi7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QI7 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qi7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qi7 RCSB], [http://www.ebi.ac.uk/pdbsum/1qi7 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qi/1qi7_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The 2.0 A resolution crystal structure of the ribosome inactivating protein saporin (isoform 6) from seeds of Saponaria officinalis is presented. The fold typical of other plant toxins is conserved, despite some differences in the loop regions. The loop between strands beta7 and beta8 in the C-terminal region which spans over the active site cleft appears shorter in saporin, suggesting an easier access to the substrate. Furthermore we investigated the molecular interaction between saporin and the yeast ribosome by differential chemical modifications. A contact surface inside the C-terminal region of saporin has been identified. Structural comparison between saporin and other ribosome inactivating proteins reveals that this region is conserved and represents a peculiar motif involved in ribosome recognition.

-	~~{{STRUCTURE_1qi7\| PDB=1qi7 \| SCENE= }}~~	+	The crystal structure of saporin SO6 from Saponaria officinalis and its interaction with the ribosome.,Savino C, Federici L, Ippoliti R, Lendaro E, Tsernoglou D FEBS Lett. 2000 Mar 31;470(3):239-43. PMID:10745075<ref>PMID:10745075</ref>

-	~~===THE CRYSTAL STRUCTURE AT 2.0 A OF SAPORIN SO6~~, ~~A RIBOSOME INACTIVATING PROTEIN FROM SAPONARIA OFFICINALIS===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10745075}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1qi7]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saponaria_officinalis Saponaria officinalis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:010745075<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Saponaria officinalis]]		[[Category: Saponaria officinalis]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]

OCA: Protected "1qi7" [edit=sysop:move=sysop]

2013-01-02T10:11:20Z

Protected "1qi7" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:11, 2 January 2013

OCA at 10:11, 2 January 2013

2013-01-02T10:11:18Z

←Older revision		Revision as of 10:11, 2 January 2013
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-	{{Seed}}
	[[Image:1qi7.png\|left\|200px]]		[[Image:1qi7.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1qi7", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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-	-->
	{{STRUCTURE_1qi7\| PDB=1qi7 \| SCENE= }}		{{STRUCTURE_1qi7\| PDB=1qi7 \| SCENE= }}

	===THE CRYSTAL STRUCTURE AT 2.0 A OF SAPORIN SO6, A RIBOSOME INACTIVATING PROTEIN FROM SAPONARIA OFFICINALIS===		===THE CRYSTAL STRUCTURE AT 2.0 A OF SAPORIN SO6, A RIBOSOME INACTIVATING PROTEIN FROM SAPONARIA OFFICINALIS===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_10745075}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 10745075 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_10745075}}		{{ABSTRACT_PUBMED_10745075}}

	==About this Structure==		==About this Structure==
-	~~1QI7~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA].	+	[[1qi7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~10745075~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:010745075</ref><references group="xtra"/>
	[[Category: Saponaria officinalis]]		[[Category: Saponaria officinalis]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]
Line 31:		Line 19:
	[[Category: Savino, C.]]		[[Category: Savino, C.]]
	[[Category: Tsernoglou, D.]]		[[Category: Tsernoglou, D.]]
		+	[[Category: Hydrolase]]
	[[Category: N-glycosidase]]		[[Category: N-glycosidase]]
	[[Category: Ribosome inactivating protein]]		[[Category: Ribosome inactivating protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:39:44 2009''

OCA at 15:39, 17 February 2009

2009-02-17T15:39:45Z

←Older revision		Revision as of 15:39, 17 February 2009
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	==About this Structure==		==About this Structure==
-	1QI7 is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA].	+	1QI7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QI7 OCA].

	==Reference==		==Reference==
-	~~The crystal structure of saporin SO6 from Saponaria officinalis and its interaction with the ribosome., Savino C, Federici L, Ippoliti R, Lendaro E, Tsernoglou D, FEBS Lett. 2000 Mar 31;470(3):239-43.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/10745075 10745075]~~	+	<ref group="xtra">PMID:10745075</ref><references group="xtra"/>
	[[Category: Saponaria officinalis]]		[[Category: Saponaria officinalis]]
-	[[Category: Single protein]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]
	[[Category: Federici, L.]]		[[Category: Federici, L.]]
Line 35:		Line 34:
	[[Category: Ribosome inactivating protein]]		[[Category: Ribosome inactivating protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 29 00~~:41:~~36 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:39:44 2009''