1qxj - Revision history

OCA at 05:57, 23 August 2023

2023-08-23T05:57:26Z

←Older revision		Revision as of 05:57, 23 August 2023
Line 3:		Line 3:
	<StructureSection load='1qxj' size='340' side='right'caption='[[1qxj]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1qxj' size='340' side='right'caption='[[1qxj]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qxj]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_43587 Atcc 43587~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1QXJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qxj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QXJ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max~~-~~height: 3em;'>[[1qxr\|1qxr]]~~, [[~~1qy4~~\|~~1qy4~~]]~~</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>PGIA OR PF0196 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~2261 ATCC 43587])</td~~><~~/tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qxj OCA], [https://pdbe.org/1qxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qxj RCSB], [https://www.ebi.ac.uk/pdbsum/1qxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qxj ProSAT]</span></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9]~~ </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1qxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qxj OCA], [~~http~~://pdbe.org/1qxj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1qxj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1qxj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1qxj ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/G6PI_PYRFU G6PI_PYRFU]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Phosphoglucoisomerase\|Phosphoglucoisomerase]]
	*[[Phosphoglucose isomerase 3D structures\|Phosphoglucose isomerase 3D structures]]		*[[Phosphoglucose isomerase 3D structures\|Phosphoglucose isomerase 3D structures]]
	== References ==		== References ==
Line 37:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 43587]]
-	[[Category: Glucose-6-phosphate isomerase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Beeson, C C]]
-	[[Category: Davies, C]]
-	[[Category: Hansen, T]]
-	[[Category: Schonheit, P]]
-	[[Category: Solomons, J T.G]]
-	[[Category: Swan, M K]]
-	[[Category: Aldose-ketose isomerase]]
-	[[Category: Cupin fold]]
-	[[Category: Extremophile]]
-	[[Category: Hyperthermophile]]
-	[[Category: Isomerase]]
-	[[Category: Phosphoglucose isomerase]]
	[[Category: Pyrococcus furiosus]]		[[Category: Pyrococcus furiosus]]
		+	[[Category: Beeson CC]]
		+	[[Category: Davies C]]
		+	[[Category: Hansen T]]
		+	[[Category: Schonheit P]]
		+	[[Category: Solomons JTG]]
		+	[[Category: Swan MK]]

OCA at 13:13, 16 December 2020

2020-12-16T13:13:33Z

←Older revision		Revision as of 13:13, 16 December 2020
Line 1:		Line 1:

	==Crystal structure of native phosphoglucose isomerase from Pyrococcus furiosus==		==Crystal structure of native phosphoglucose isomerase from Pyrococcus furiosus==
-	<StructureSection load='1qxj' size='340' side='right' caption='[[1qxj]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='1qxj' size='340' side='right'caption='[[1qxj]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qxj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXJ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1QXJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qxj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXJ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1QXJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qxr\|1qxr]], [[1qy4\|1qy4]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1qxr\|1qxr]], [[1qy4\|1qy4]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGIA OR PF0196 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGIA OR PF0196 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1qxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qxj OCA], [http://pdbe.org/1qxj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qxj RCSB], [http://www.ebi.ac.uk/pdbsum/1qxj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qxj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1qxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qxj OCA], [http://pdbe.org/1qxj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qxj RCSB], [http://www.ebi.ac.uk/pdbsum/1qxj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qxj ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 32:		Line 32:
	==See Also==		==See Also==
	*[[Phosphoglucoisomerase\|Phosphoglucoisomerase]]		*[[Phosphoglucoisomerase\|Phosphoglucoisomerase]]
		+	*[[Phosphoglucose isomerase 3D structures\|Phosphoglucose isomerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 38:		Line 39:
	[[Category: Atcc 43587]]		[[Category: Atcc 43587]]
	[[Category: Glucose-6-phosphate isomerase]]		[[Category: Glucose-6-phosphate isomerase]]
		+	[[Category: Large Structures]]
	[[Category: Beeson, C C]]		[[Category: Beeson, C C]]
	[[Category: Davies, C]]		[[Category: Davies, C]]

OCA at 07:40, 28 February 2018

2018-02-28T07:40:03Z

←Older revision		Revision as of 07:40, 28 February 2018
Line 1:		Line 1:
		+
	==Crystal structure of native phosphoglucose isomerase from Pyrococcus furiosus==		==Crystal structure of native phosphoglucose isomerase from Pyrococcus furiosus==
	<StructureSection load='1qxj' size='340' side='right' caption='[[1qxj]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1qxj' size='340' side='right' caption='[[1qxj]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGIA OR PF0196 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGIA OR PF0196 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qxj OCA], [http://pdbe.org/1qxj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qxj RCSB], [http://www.ebi.ac.uk/pdbsum/1qxj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qxj OCA], [http://pdbe.org/1qxj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qxj RCSB], [http://www.ebi.ac.uk/pdbsum/1qxj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qxj ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qx/1qxj_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qx/1qxj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 31:		Line 32:
	==See Also==		==See Also==
	*[[Phosphoglucoisomerase\|Phosphoglucoisomerase]]		*[[Phosphoglucoisomerase\|Phosphoglucoisomerase]]
-	*[[Phosphoglucose isomerase\|Phosphoglucose isomerase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:51, 8 February 2016

2016-02-08T10:51:27Z

←Older revision		Revision as of 10:51, 8 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qxj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:50, 10 September 2015

2015-09-10T10:50:00Z

←Older revision		Revision as of 10:50, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1qxj' size='340' side='right' caption='[[1qxj]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1qxj' size='340' side='right' caption='[[1qxj]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qxj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pyrococcus_furiosus Pyrococcus furiosus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QXJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qxj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QXJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qxr\|1qxr]], [[1qy4\|1qy4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qxr\|1qxr]], [[1qy4\|1qy4]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGIA OR PF0196 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ~~Pyrococcus furiosus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGIA OR PF0196 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qxj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qxj RCSB], [http://www.ebi.ac.uk/pdbsum/1qxj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qxj OCA], [http://pdbe.org/1qxj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qxj RCSB], [http://www.ebi.ac.uk/pdbsum/1qxj PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1qxj" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 43587]]
	[[Category: Glucose-6-phosphate isomerase]]		[[Category: Glucose-6-phosphate isomerase]]
-	[[Category: Pyrococcus furiosus]]
	[[Category: Beeson, C C]]		[[Category: Beeson, C C]]
	[[Category: Davies, C]]		[[Category: Davies, C]]
Line 49:		Line 50:
	[[Category: Isomerase]]		[[Category: Isomerase]]
	[[Category: Phosphoglucose isomerase]]		[[Category: Phosphoglucose isomerase]]
		+	[[Category: Pyrococcus furiosus]]

OCA at 07:46, 6 January 2015

2015-01-06T07:46:36Z

←Older revision		Revision as of 07:46, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qxj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QXJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qxj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QXJ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qxr\|1qxr]], [[1qy4\|1qy4]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qxr\|1qxr]], [[1qy4\|1qy4]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGIA OR PF0196 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 Pyrococcus furiosus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGIA OR PF0196 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 Pyrococcus furiosus])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qxj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qxj RCSB], [http://www.ebi.ac.uk/pdbsum/1qxj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qxj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qxj RCSB], [http://www.ebi.ac.uk/pdbsum/1qxj PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 37:
	[[Category: Glucose-6-phosphate isomerase]]		[[Category: Glucose-6-phosphate isomerase]]
	[[Category: Pyrococcus furiosus]]		[[Category: Pyrococcus furiosus]]
-	[[Category: Beeson, C C.]]	+	[[Category: Beeson, C C]]
-	[[Category: Davies, C.]]	+	[[Category: Davies, C]]
-	[[Category: Hansen, T.]]	+	[[Category: Hansen, T]]
-	[[Category: Schonheit, P.]]	+	[[Category: Schonheit, P]]
-	[[Category: Solomons, J T.G.]]	+	[[Category: Solomons, J T.G]]
-	[[Category: Swan, M K.]]	+	[[Category: Swan, M K]]
	[[Category: Aldose-ketose isomerase]]		[[Category: Aldose-ketose isomerase]]
	[[Category: Cupin fold]]		[[Category: Cupin fold]]
Line 49:		Line 49:
	[[Category: Isomerase]]		[[Category: Isomerase]]
	[[Category: Phosphoglucose isomerase]]		[[Category: Phosphoglucose isomerase]]
-	[[Category: Pyrococcus furiosus]]

OCA at 14:27, 29 September 2014

2014-09-29T14:27:05Z

←Older revision		Revision as of 14:27, 29 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1qxj\| PDB~~=1qxj \| ~~SCENE~~= }}	+	==Crystal structure of native phosphoglucose isomerase from Pyrococcus furiosus==
-	===~~Crystal~~ structure ~~of native phosphoglucose isomerase~~ from Pyrococcus furiosus===	+	<StructureSection load='1qxj' size='340' side='right' caption='[[1qxj]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~{{ABSTRACT_PUBMED_12970347}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1qxj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QXJ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qxr\|1qxr]], [[1qy4\|1qy4]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGIA OR PF0196 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 Pyrococcus furiosus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qxj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qxj RCSB], [http://www.ebi.ac.uk/pdbsum/1qxj PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qx/1qxj_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In the Euryarchaeota species Pyrococcus furiosus and Thermococcus litoralis, phosphoglucose isomerase (PGI) activity is catalyzed by an enzyme unrelated to the well known family of PGI enzymes found in prokaryotes, eukaryotes, and some archaea. We have determined the crystal structure of PGI from Pyrococcus furiosus in native form and in complex with two active site ligands, 5-phosphoarabinonate and gluconate 6-phosphate. In these structures, the metal ion, which in vivo is presumed to be Fe2+, is located in the core of the cupin fold and is immediately adjacent to the C1-C2 region of the ligands, suggesting that Fe2+ is involved in catalysis rather than serving a structural role. The active site contains a glutamate residue that contacts the substrate, but, because it is also coordinated to the metal ion, it is highly unlikely to mediate proton transfer in a cis-enediol mechanism. Consequently, we propose a hydride shift mechanism of catalysis. In this mechanism, Fe2+ is responsible for proton transfer between O1 and O2, and the hydride shift between C1 and C2 is favored by a markedly hydrophobic environment in the active site. The absence of any obvious enzymatic machinery for catalyzing ring opening of the sugar substrates suggests that pyrococcal PGI has a preference for straight chain substrates and that metabolism in extreme thermophiles may use sugars in both ring and straight chain forms.

-	~~==About this Structure==~~	+	Structural evidence for a hydride transfer mechanism of catalysis in phosphoglucose isomerase from Pyrococcus furiosus.,Swan MK, Solomons JT, Beeson CC, Hansen T, Schonheit P, Davies C J Biol Chem. 2003 Nov 21;278(47):47261-8. Epub 2003 Sep 11. PMID:12970347<ref>PMID:12970347</ref>
-	~~[[1qxj]] is~~ a ~~2 chain structure with sequence~~ from ~~[http://en.wikipedia.org/wiki/Pyrococcus_furiosus~~ Pyrococcus furiosus]. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=1QXJ OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Phosphoglucoisomerase\|Phosphoglucoisomerase]]		*[[Phosphoglucoisomerase\|Phosphoglucoisomerase]]
	*[[Phosphoglucose isomerase\|Phosphoglucose isomerase]]		*[[Phosphoglucose isomerase\|Phosphoglucose isomerase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:012970347<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Glucose-6-phosphate isomerase]]		[[Category: Glucose-6-phosphate isomerase]]
	[[Category: Pyrococcus furiosus]]		[[Category: Pyrococcus furiosus]]

OCA at 09:44, 11 March 2013

2013-03-11T09:44:47Z

←Older revision		Revision as of 09:44, 11 March 2013
Line 1:		Line 1:
-	[[Image:1qxj.png\|left\|200px]]
-
	{{STRUCTURE_1qxj\| PDB=1qxj \| SCENE= }}		{{STRUCTURE_1qxj\| PDB=1qxj \| SCENE= }}
-
	===Crystal structure of native phosphoglucose isomerase from Pyrococcus furiosus===		===Crystal structure of native phosphoglucose isomerase from Pyrococcus furiosus===
-
	{{ABSTRACT_PUBMED_12970347}}		{{ABSTRACT_PUBMED_12970347}}

OCA at 09:55, 20 October 2012

2012-10-20T09:55:01Z

←Older revision		Revision as of 09:55, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1qxj]] is a 2 chain structure ~~of [[Phosphoglucose isomerase]]~~ with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXJ OCA].	+	[[1qxj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QXJ OCA].

	==See Also==		==See Also==

OCA: Protected "1qxj" [edit=sysop:move=sysop]

2012-07-26T00:21:50Z

Protected "1qxj" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:21, 26 July 2012