1qzw - Revision history

OCA at 05:58, 23 August 2023

2023-08-23T05:58:35Z

←Older revision		Revision as of 05:58, 23 August 2023
Line 3:		Line 3:
	<StructureSection load='1qzw' size='340' side='right'caption='[[1qzw]], [[Resolution\|resolution]] 4.10Å' scene=''>		<StructureSection load='1qzw' size='340' side='right'caption='[[1qzw]], [[Resolution\|resolution]] 4.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qzw]] is a 8 chain structure with sequence from [~~http://en.wikipedia.org/wiki/ ] and [http~~://en.wikipedia.org/wiki/~~Atcc_35091 Atcc 35091~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1QZW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qzw]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QZW FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=CCC:CYTIDINE~~-~~5-PHOSPHATE-2~~,~~3-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 4.1Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[1j8m\|1j8m]], [[1hq1\|1hq1]], [[1qzx\|1qzx]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CCC:CYTIDINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">SRP54 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzw OCA], [https://pdbe.org/1qzw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qzw RCSB], [https://www.ebi.ac.uk/pdbsum/1qzw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qzw ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1qzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzw OCA], [~~http~~://pdbe.org/1qzw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1qzw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1qzw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1qzw ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~SRP54_SULSO SRP54_SULSO]~~] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ~~(By similarity)~~.	+	[https://www.uniprot.org/uniprot/SRP54_SACS2 SRP54_SACS2] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.[HAMAP-Rule:MF_00306]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 35091]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Montoya, G]]	+	[[Category: Saccharolobus solfataricus]]
-	[[Category: Rosendal~~, K R~~]]	+	[[Category: Montoya G]]
-	[[Category: Sinning, I]]	+	[[Category: Rosendal KR]]
-	[[Category: Wild, K]]	+	[[Category: Sinning I]]
-	~~[[Category: Protein targeting]]~~	+	[[Category: Wild K]]
-	~~[[Category: Protein-rna complex]]~~	+
-	~~[[Category: Ribonucleoprotein complex]]~~	+
-	~~[[Category: Signal recognition particle]]~~	+
-	~~[[Category: Signaling protein-rna complex]]~~	+
-	~~[[Category: Srp~~]]	+

OCA at 13:15, 16 December 2020

2020-12-16T13:15:03Z

←Older revision		Revision as of 13:15, 16 December 2020
Line 1:		Line 1:

	==Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication==		==Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication==
-	<StructureSection load='1qzw' size='340' side='right' caption='[[1qzw]], [[Resolution\|resolution]] 4.10Å' scene=''>	+	<StructureSection load='1qzw' size='340' side='right'caption='[[1qzw]], [[Resolution\|resolution]] 4.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qzw]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1QZW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qzw]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1QZW FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CCC:CYTIDINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CCC:CYTIDINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j8m\|1j8m]], [[1hq1\|1hq1]], [[1qzx\|1qzx]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1j8m\|1j8m]], [[1hq1\|1hq1]], [[1qzx\|1qzx]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SRP54 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SRP54 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1qzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzw OCA], [http://pdbe.org/1qzw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qzw RCSB], [http://www.ebi.ac.uk/pdbsum/1qzw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qzw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1qzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzw OCA], [http://pdbe.org/1qzw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qzw RCSB], [http://www.ebi.ac.uk/pdbsum/1qzw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qzw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 38:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 35091]]		[[Category: Atcc 35091]]
		+	[[Category: Large Structures]]
	[[Category: Montoya, G]]		[[Category: Montoya, G]]
	[[Category: Rosendal, K R]]		[[Category: Rosendal, K R]]

OCA at 08:02, 28 February 2018

2018-02-28T08:02:24Z

←Older revision		Revision as of 08:02, 28 February 2018
Line 1:		Line 1:
		+
	==Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication==		==Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication==
	<StructureSection load='1qzw' size='340' side='right' caption='[[1qzw]], [[Resolution\|resolution]] 4.10Å' scene=''>		<StructureSection load='1qzw' size='340' side='right' caption='[[1qzw]], [[Resolution\|resolution]] 4.10Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j8m\|1j8m]], [[1hq1\|1hq1]], [[1qzx\|1qzx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j8m\|1j8m]], [[1hq1\|1hq1]], [[1qzx\|1qzx]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SRP54 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SRP54 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzw OCA], [http://pdbe.org/1qzw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qzw RCSB], [http://www.ebi.ac.uk/pdbsum/1qzw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzw OCA], [http://pdbe.org/1qzw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qzw RCSB], [http://www.ebi.ac.uk/pdbsum/1qzw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qzw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qz/1qzw_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qz/1qzw_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 03:25, 10 February 2016

2016-02-10T03:25:11Z

←Older revision		Revision as of 03:25, 10 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qzw ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:54, 11 September 2015

2015-09-11T04:54:18Z

←Older revision		Revision as of 04:54, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1qzw' size='340' side='right' caption='[[1qzw]], [[Resolution\|resolution]] 4.10Å' scene=''>		<StructureSection load='1qzw' size='340' side='right' caption='[[1qzw]], [[Resolution\|resolution]] 4.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qzw]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sulfolobus_solfataricus Sulfolobus solfataricus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QZW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qzw]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QZW FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CCC:CYTIDINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CCC:CYTIDINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j8m\|1j8m]], [[1hq1\|1hq1]], [[1qzx\|1qzx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j8m\|1j8m]], [[1hq1\|1hq1]], [[1qzx\|1qzx]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">~~7S RNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus]),~~ SRP54 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ~~Sulfolobus solfataricus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SRP54 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qzw RCSB], [http://www.ebi.ac.uk/pdbsum/1qzw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzw OCA], [http://pdbe.org/1qzw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qzw RCSB], [http://www.ebi.ac.uk/pdbsum/1qzw PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1qzw" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Sulfolobus solfataricus~~]]	+	[[Category: Atcc 35091]]
	[[Category: Montoya, G]]		[[Category: Montoya, G]]
	[[Category: Rosendal, K R]]		[[Category: Rosendal, K R]]

OCA at 11:27, 25 December 2014

2014-12-25T11:27:51Z

←Older revision		Revision as of 11:27, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qzw]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QZW FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qzw]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QZW FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CCC:CYTIDINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CCC:CYTIDINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j8m\|1j8m]], [[1hq1\|1hq1]], [[1qzx\|1qzx]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j8m\|1j8m]], [[1hq1\|1hq1]], [[1qzx\|1qzx]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">7S RNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus]), SRP54 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">7S RNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus]), SRP54 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qzw RCSB], [http://www.ebi.ac.uk/pdbsum/1qzw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qzw RCSB], [http://www.ebi.ac.uk/pdbsum/1qzw PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SRP54_SULSO SRP54_SULSO]] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
-	[[Category: Montoya, G.]]	+	[[Category: Montoya, G]]
-	[[Category: Rosendal, K R.]]	+	[[Category: Rosendal, K R]]
-	[[Category: Sinning, I.]]	+	[[Category: Sinning, I]]
-	[[Category: Wild, K.]]	+	[[Category: Wild, K]]
	[[Category: Protein targeting]]		[[Category: Protein targeting]]
	[[Category: Protein-rna complex]]		[[Category: Protein-rna complex]]

OCA at 14:11, 29 September 2014

2014-09-29T14:11:37Z

←Older revision		Revision as of 14:11, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1qzw.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication==
		+	<StructureSection load='1qzw' size='340' side='right' caption='[[1qzw]], [[Resolution\|resolution]] 4.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1qzw]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QZW FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CCC:CYTIDINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j8m\|1j8m]], [[1hq1\|1hq1]], [[1qzx\|1qzx]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">7S RNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus]), SRP54 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qzw RCSB], [http://www.ebi.ac.uk/pdbsum/1qzw PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qz/1qzw_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Targeting of secretory and membrane proteins by the signal recognition particle (SRP) is evolutionarily conserved, and the multidomain protein SRP54 acts as the key player in SRP-mediated protein transport. Binding of a signal peptide to SRP54 at the ribosome is coordinated with GTP binding and subsequent complex formation with the SRP receptor. Because these functions are localized to distinct domains of SRP54, communication between them is essential. We report the crystal structures of SRP54 from the Archaeon Sulfolobus solfataricus with and without its cognate SRP RNA binding site (helix 8) at 4-A resolution. The two structures show the flexibility of the SRP core and the position of SRP54 relative to the RNA. A long linker helix connects the GTPase (G domain) with the signal peptide binding (M) domain, and a hydrophobic contact between the N and M domains relates the signal peptide binding site to the G domain. Hinge regions are identified in the linker between the G and M domains (292-LGMGD) and in the N-terminal part of the M domain, which allow for structural rearrangements within SRP54 upon signal peptide binding at the ribosome.

-	~~{{STRUCTURE_1qzw\| PDB=1qzw \| SCENE= }}~~	+	Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication.,Rosendal KR, Wild K, Montoya G, Sinning I Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14701-6. Epub 2003 Dec 1. PMID:14657338<ref>PMID:14657338</ref>

-	~~===Crystal structure~~ of the ~~complete core~~ of ~~archaeal SRP and implications for inter-domain communication===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_14657338}}~~	+	==See Also==
-		+	*[[Signal recognition particle protein\|Signal recognition particle protein]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1qzw~~]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:014657338<~~/~~ref~~><~~ref group="xtra">PMID:016299512</ref><ref group="xtra">PMID:020364120</ref><references group="xtra"~~/>	+
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
	[[Category: Montoya, G.]]		[[Category: Montoya, G.]]

OCA: Protected "1qzw" [edit=sysop:move=sysop]

2013-01-04T10:36:31Z

Protected "1qzw" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:36, 4 January 2013

OCA at 10:36, 4 January 2013

2013-01-04T10:36:27Z

←Older revision		Revision as of 10:36, 4 January 2013
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-	{{Seed}}
	[[Image:1qzw.png\|left\|200px]]		[[Image:1qzw.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1qzw", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1qzw\| PDB=1qzw \| SCENE= }}		{{STRUCTURE_1qzw\| PDB=1qzw \| SCENE= }}

	===Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication===		===Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_14657338}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 14657338 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_14657338}}		{{ABSTRACT_PUBMED_14657338}}

	==About this Structure==		==About this Structure==
-	~~1QZW~~ is a 8 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA].	+	[[1qzw]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~14657338~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:014657338</ref><ref group="xtra">PMID:016299512</ref><ref group="xtra">PMID:020364120</ref><references group="xtra"/>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
	[[Category: Montoya, G.]]		[[Category: Montoya, G.]]
Line 35:		Line 23:
	[[Category: Signaling protein-rna complex]]		[[Category: Signaling protein-rna complex]]
	[[Category: Srp]]		[[Category: Srp]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:24:23 2010''

OCA at 06:11, 22 December 2010

2010-12-22T06:11:47Z

←Older revision		Revision as of 06:11, 22 December 2010
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1QZW is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA].	+	1QZW is a 8 chains structure with sequences from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZW OCA].

	==Reference==		==Reference==
Line 33:		Line 33:
	[[Category: Ribonucleoprotein complex]]		[[Category: Ribonucleoprotein complex]]
	[[Category: Signal recognition particle]]		[[Category: Signal recognition particle]]
-	[[Category: Signaling protein/rna complex]]	+	[[Category: Signaling protein-rna complex]]
	[[Category: Srp]]		[[Category: Srp]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~May 13 10~~:43:~~44 2009~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:24:23 2010''