1sjp - Revision history

OCA at 07:26, 25 October 2023

2023-10-25T07:26:13Z

←Older revision		Revision as of 07:26, 25 October 2023
Line 3:		Line 3:
	<StructureSection load='1sjp' size='340' side='right'caption='[[1sjp]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='1sjp' size='340' side='right'caption='[[1sjp]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1sjp]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus~~ tuberculosis~~" (zopf 1883) klein 1884~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1SJP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1sjp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SJP FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>Rv0440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~1773~~ "~~Bacillus tuberculosis~~" ~~(Zopf 1883) Klein 1884~~])</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.2Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1sjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sjp OCA], [~~http~~://pdbe.org/1sjp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1sjp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1sjp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1sjp ProSAT], [~~http~~://www.topsan.org/Proteins/TBSGC/1sjp TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sjp OCA], [https://pdbe.org/1sjp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sjp RCSB], [https://www.ebi.ac.uk/pdbsum/1sjp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sjp ProSAT], [https://www.topsan.org/Proteins/TBSGC/1sjp TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CH602_MYCTU CH602_MYCTU]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).[HAMAP-Rule:MF_00600]	+	[https://www.uniprot.org/uniprot/CH602_MYCTU CH602_MYCTU] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).[HAMAP-Rule:MF_00600]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Mande, S C~~]]	+	[[Category: Mycobacterium tuberculosis]]
-	[[Category: ~~Qamra, R~~]]	+	[[Category: Mande SC]]
-	[[Category: ~~Structural genomic]]~~	+	[[Category: Qamra R]]
-	~~[[Category: Chaperone]]~~	+
-	~~[[Category: PSI, Protein structure initiative]]~~	+
-	~~[[Category: Tbsgc~~]]	+

OCA at 11:28, 24 December 2020

2020-12-24T11:28:06Z

←Older revision		Revision as of 11:28, 24 December 2020
Line 1:		Line 1:

	==Mycobacterium tuberculosis Chaperonin60.2==		==Mycobacterium tuberculosis Chaperonin60.2==
-	<StructureSection load='1sjp' size='340' side='right' caption='[[1sjp]], [[Resolution\|resolution]] 3.20Å' scene=''>	+	<StructureSection load='1sjp' size='340' side='right'caption='[[1sjp]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1sjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1SJP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1sjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1SJP FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1sjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sjp OCA], [http://pdbe.org/1sjp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sjp RCSB], [http://www.ebi.ac.uk/pdbsum/1sjp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1sjp ProSAT], [http://www.topsan.org/Proteins/TBSGC/1sjp TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1sjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sjp OCA], [http://pdbe.org/1sjp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sjp RCSB], [http://www.ebi.ac.uk/pdbsum/1sjp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1sjp ProSAT], [http://www.topsan.org/Proteins/TBSGC/1sjp TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Chaperonin\|Chaperonin]]	+	*[[Chaperonin 3D structures\|Chaperonin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Mande, S C]]		[[Category: Mande, S C]]
	[[Category: Qamra, R]]		[[Category: Qamra, R]]

OCA at 08:05, 14 March 2018

2018-03-14T08:05:39Z

←Older revision		Revision as of 08:05, 14 March 2018
Line 1:		Line 1:
		+
	==Mycobacterium tuberculosis Chaperonin60.2==		==Mycobacterium tuberculosis Chaperonin60.2==
	<StructureSection load='1sjp' size='340' side='right' caption='[[1sjp]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='1sjp' size='340' side='right' caption='[[1sjp]], [[Resolution\|resolution]] 3.20Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1sjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SJP FirstGlance]. <br>		<table><tr><td colspan='2'>[[1sjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SJP FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sjp OCA], [http://pdbe.org/1sjp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sjp RCSB], [http://www.ebi.ac.uk/pdbsum/1sjp PDBsum], [http://www.topsan.org/Proteins/TBSGC/1sjp TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sjp OCA], [http://pdbe.org/1sjp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sjp RCSB], [http://www.ebi.ac.uk/pdbsum/1sjp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1sjp ProSAT], [http://www.topsan.org/Proteins/TBSGC/1sjp TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sj/1sjp_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sj/1sjp_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 20:58, 8 February 2016

2016-02-08T20:58:59Z

←Older revision		Revision as of 20:58, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sjp ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:20, 10 September 2015

2015-09-10T15:20:06Z

←Older revision		Revision as of 15:20, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1sjp' size='340' side='right' caption='[[1sjp]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='1sjp' size='340' side='right' caption='[[1sjp]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1sjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mycobacterium_tuberculosis Mycobacterium~~ tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SJP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1sjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SJP FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 ~~Mycobacterium~~ tuberculosis])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sjp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sjp RCSB], [http://www.ebi.ac.uk/pdbsum/1sjp PDBsum], [http://www.topsan.org/Proteins/TBSGC/1sjp TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sjp OCA], [http://pdbe.org/1sjp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sjp RCSB], [http://www.ebi.ac.uk/pdbsum/1sjp PDBsum], [http://www.topsan.org/Proteins/TBSGC/1sjp TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1sjp" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Mycobacterium tuberculosis]]
	[[Category: Mande, S C]]		[[Category: Mande, S C]]
	[[Category: Qamra, R]]		[[Category: Qamra, R]]

OCA at 02:06, 25 December 2014

2014-12-25T02:06:26Z

←Older revision		Revision as of 02:06, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1sjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SJP FirstGlance]. <br>		<table><tr><td colspan='2'>[[1sjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SJP FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sjp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sjp RCSB], [http://www.ebi.ac.uk/pdbsum/1sjp PDBsum], [http://www.topsan.org/Proteins/TBSGC/1sjp TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sjp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sjp RCSB], [http://www.ebi.ac.uk/pdbsum/1sjp PDBsum], [http://www.topsan.org/Proteins/TBSGC/1sjp TOPSAN]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CH602_MYCTU CH602_MYCTU]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).[HAMAP-Rule:MF_00600]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
-	[[Category: Mande, S C.]]	+	[[Category: Mande, S C]]
-	[[Category: Qamra, R~~.]]~~	+	[[Category: Qamra, R]]
-	~~[[Category: TBSGC, TB Structural Genomics Consortium.]]~~	+
-	~~[[Category: Chaperone]]~~	+
-	~~[[Category: Protein structure initiative]]~~	+
-	~~[[Category: Psi~~]]	+
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
-	[[Category: ~~Tb structural genomics consortium~~]]	+	[[Category: Chaperone]]
		+	[[Category: PSI, Protein structure initiative]]
	[[Category: Tbsgc]]		[[Category: Tbsgc]]

OCA at 23:38, 28 September 2014

2014-09-28T23:38:45Z

←Older revision		Revision as of 23:38, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1sjp.~~png\|left~~\|200px]]	+	==Mycobacterium tuberculosis Chaperonin60.2==
		+	<StructureSection load='1sjp' size='340' side='right' caption='[[1sjp]], [[Resolution\|resolution]] 3.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1sjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SJP FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sjp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sjp RCSB], [http://www.ebi.ac.uk/pdbsum/1sjp PDBsum], [http://www.topsan.org/Proteins/TBSGC/1sjp TOPSAN]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sj/1sjp_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Chaperonin 60s are a ubiquitous class of proteins that promote folding and assembly of other cellular polypeptides in an ATP-dependent manner. The oligomeric state of chaperonin 60s has been shown to be crucial to their role as molecular chaperones. Chaperonin 60s are also known to be important stimulators of the immune system. Mycobacterium tuberculosis possesses a duplicate set of chaperonin 60s, both of which have been shown to be potent cytokine stimulators. The M. tuberculosis chaperonin 60s are present in the extracellular milieu at concentrations that are extremely low for the formation of an oligomer. Here we present the crystal structure of one of the chaperonin 60s of M. tuberculosis, also called Hsp65 or chaperonin 60.2, at 3.2-A resolution. We were able to crystallize the protein in its dimeric state. The unusual dimerization of the protein leads to exposure of certain hydrophobic patches on the surface of the protein, and we hypothesize that this might have relevance in binding to immunogenic peptides, as it does in the eukaryotic homologs.

-	~~{{STRUCTURE_1sjp\| PDB=1sjp \| SCENE= }}~~	+	Crystal structure of the 65-kilodalton heat shock protein, chaperonin 60.2, of Mycobacterium tuberculosis.,Qamra R, Mande SC J Bacteriol. 2004 Dec;186(23):8105-13. PMID:15547284<ref>PMID:15547284</ref>

-	~~===Mycobacterium tuberculosis Chaperonin60.2===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15547284}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1sjp]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA].~~	+

	==See Also==		==See Also==
	*[[Chaperonin\|Chaperonin]]		*[[Chaperonin\|Chaperonin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:015547284<~~/~~ref~~><~~ref group="xtra">PMID:015327959</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
	[[Category: Mande, S C.]]		[[Category: Mande, S C.]]

OCA at 11:27, 20 October 2012

2012-10-20T11:27:36Z

←Older revision		Revision as of 11:27, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1sjp]] is a 2 chain structure ~~of [[Chaperonin]]~~ with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA].	+	[[1sjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA].

	==See Also==		==See Also==

OCA at 05:26, 26 July 2012

2012-07-26T05:26:54Z

←Older revision		Revision as of 05:26, 26 July 2012
Line 1:		Line 1:
	[[Image:1sjp.png\|left\|200px]]		[[Image:1sjp.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1sjp", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1sjp\| PDB=1sjp \| SCENE= }}		{{STRUCTURE_1sjp\| PDB=1sjp \| SCENE= }}

	===Mycobacterium tuberculosis Chaperonin60.2===		===Mycobacterium tuberculosis Chaperonin60.2===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15547284}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15547284 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_15547284}}		{{ABSTRACT_PUBMED_15547284}}

	==About this Structure==		==About this Structure==
-	[[1sjp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA].	+	[[1sjp]] is a 2 chain structure of [[Chaperonin]] with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJP OCA].
		+
		+	==See Also==
		+	*[[Chaperonin\|Chaperonin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15547284~~</ref><ref group="xtra">PMID:~~15327959~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015547284</ref><ref group="xtra">PMID:015327959</ref><references group="xtra"/>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
	[[Category: Mande, S C.]]		[[Category: Mande, S C.]]

OCA: Protected "1sjp" [edit=sysop:move=sysop]

2011-03-14T22:56:52Z

Protected "1sjp" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:56, 14 March 2011