1skq - Revision history

OCA at 06:18, 23 August 2023

2023-08-23T06:18:21Z

←Older revision		Revision as of 06:18, 23 August 2023
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	<StructureSection load='1skq' size='340' side='right'caption='[[1skq]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1skq' size='340' side='right'caption='[[1skq]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1skq]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_35091 Atcc 35091~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1SKQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1skq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SKQ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GDP:GUANOSINE~~-~~5-DIPHOSPHATE'>GDP</scene>~~, ~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[1jny\|1jny]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">TUF, TEF1, SSO0216 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1skq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1skq OCA], [https://pdbe.org/1skq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1skq RCSB], [https://www.ebi.ac.uk/pdbsum/1skq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1skq ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1skq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1skq OCA], [~~http~~://pdbe.org/1skq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1skq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1skq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1skq ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~EF1A_SULSO EF1A_SULSO]~~] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.	+	[https://www.uniprot.org/uniprot/EF1A_SACS2 EF1A_SACS2] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 35091]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arcari, P]]	+	[[Category: Saccharolobus solfataricus]]
-	[[Category: Cantiello, P]]	+	[[Category: Arcari P]]
-	[[Category: Masullo, M]]	+	[[Category: Cantiello P]]
-	[[Category: Ruggiero, A]]	+	[[Category: Masullo M]]
-	[[Category: Vitagliano, L]]	+	[[Category: Ruggiero A]]
-	[[Category: Zagari, A]]	+	[[Category: Vitagliano L]]
-	~~[[Category: Archaea]]~~	+	[[Category: Zagari A]]
-	~~[[Category: Elongation factor]]~~	+
-	~~[[Category: Protein synthesis]]~~	+
-	~~[[Category: Translation~~]]	+

OCA at 11:28, 24 December 2020

2020-12-24T11:28:44Z

←Older revision		Revision as of 11:28, 24 December 2020
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	==The crystal structure of Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP==		==The crystal structure of Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP==
-	<StructureSection load='1skq' size='340' side='right' caption='[[1skq]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='1skq' size='340' side='right'caption='[[1skq]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1skq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1SKQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1skq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1SKQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jny\|1jny]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1jny\|1jny]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TUF, TEF1, SSO0216 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TUF, TEF1, SSO0216 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1skq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1skq OCA], [http://pdbe.org/1skq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1skq RCSB], [http://www.ebi.ac.uk/pdbsum/1skq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1skq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1skq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1skq OCA], [http://pdbe.org/1skq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1skq RCSB], [http://www.ebi.ac.uk/pdbsum/1skq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1skq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</div>		</div>
	<div class="pdbe-citations 1skq" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1skq" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Elongation factor 3D structures\|Elongation factor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 35091]]		[[Category: Atcc 35091]]
		+	[[Category: Large Structures]]
	[[Category: Arcari, P]]		[[Category: Arcari, P]]
	[[Category: Cantiello, P]]		[[Category: Cantiello, P]]

OCA at 06:44, 15 February 2018

2018-02-15T06:44:55Z

←Older revision		Revision as of 06:44, 15 February 2018
Line 1:		Line 1:
		+
	==The crystal structure of Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP==		==The crystal structure of Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP==
	<StructureSection load='1skq' size='340' side='right' caption='[[1skq]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1skq' size='340' side='right' caption='[[1skq]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jny\|1jny]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jny\|1jny]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TUF, TEF1, SSO0216 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TUF, TEF1, SSO0216 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1skq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1skq OCA], [http://pdbe.org/1skq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1skq RCSB], [http://www.ebi.ac.uk/pdbsum/1skq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1skq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1skq OCA], [http://pdbe.org/1skq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1skq RCSB], [http://www.ebi.ac.uk/pdbsum/1skq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1skq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sk/1skq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sk/1skq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 29:		Line 30:
	</div>		</div>
	<div class="pdbe-citations 1skq" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1skq" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Elongation factor\|Elongation factor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 23:50, 7 February 2016

2016-02-07T23:50:21Z

←Older revision		Revision as of 23:50, 7 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1skq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:59, 10 September 2015

2015-09-10T05:59:03Z

←Older revision		Revision as of 05:59, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1skq' size='340' side='right' caption='[[1skq]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1skq' size='340' side='right' caption='[[1skq]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1skq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sulfolobus_solfataricus Sulfolobus solfataricus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SKQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1skq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SKQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jny\|1jny]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jny\|1jny]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TUF, TEF1, SSO0216 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ~~Sulfolobus solfataricus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TUF, TEF1, SSO0216 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1skq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1skq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1skq RCSB], [http://www.ebi.ac.uk/pdbsum/1skq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1skq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1skq OCA], [http://pdbe.org/1skq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1skq RCSB], [http://www.ebi.ac.uk/pdbsum/1skq PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1skq" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Sulfolobus solfataricus~~]]	+	[[Category: Atcc 35091]]
	[[Category: Arcari, P]]		[[Category: Arcari, P]]
	[[Category: Cantiello, P]]		[[Category: Cantiello, P]]

OCA at 19:04, 24 December 2014

2014-12-24T19:04:14Z

←Older revision		Revision as of 19:04, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1skq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SKQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1skq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SKQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jny\|1jny]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jny\|1jny]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TUF, TEF1, SSO0216 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TUF, TEF1, SSO0216 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1skq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1skq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1skq RCSB], [http://www.ebi.ac.uk/pdbsum/1skq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1skq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1skq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1skq RCSB], [http://www.ebi.ac.uk/pdbsum/1skq PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/EF1A_SULSO EF1A_SULSO]] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
-	[[Category: Arcari, P.]]	+	[[Category: Arcari, P]]
-	[[Category: Cantiello, P.]]	+	[[Category: Cantiello, P]]
-	[[Category: Masullo, M.]]	+	[[Category: Masullo, M]]
-	[[Category: Ruggiero, A.]]	+	[[Category: Ruggiero, A]]
-	[[Category: Vitagliano, L.]]	+	[[Category: Vitagliano, L]]
-	[[Category: Zagari, A.]]	+	[[Category: Zagari, A]]
	[[Category: Archaea]]		[[Category: Archaea]]
	[[Category: Elongation factor]]		[[Category: Elongation factor]]
	[[Category: Protein synthesis]]		[[Category: Protein synthesis]]
	[[Category: Translation]]		[[Category: Translation]]

OCA at 21:24, 28 September 2014

2014-09-28T21:24:12Z

←Older revision		Revision as of 21:24, 28 September 2014
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-	[[~~Image:~~1skq.~~png~~\|~~left~~\|200px]]	+	==The crystal structure of Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP==
		+	<StructureSection load='1skq' size='340' side='right' caption='[[1skq]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1skq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SKQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jny\|1jny]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TUF, TEF1, SSO0216 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1skq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1skq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1skq RCSB], [http://www.ebi.ac.uk/pdbsum/1skq PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sk/1skq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Recent studies have shown that elongation factors extracted from archaea/eukarya and from eubacteria exhibit different structural and functional properties. Along this line, it has been demonstrated that, in contrast to EF-Tu, Sulfolobus solfataricus EF-1alpha in complex with GDP (SsEF-1alpha.GDP) does not bind Mg(2+), when the ion is present in the crystallization medium at moderate concentration (5 mM). To further investigate the role that magnesium plays in the exchange process of EF-1alpha and to check the ability of SsEF-1alpha.GDP to bind the ion, we have determined the crystal structure of SsEF-1alpha.GDP in the presence of a nonphysiological concentration (100 mM) of Mg(2+). The analysis of the coordination of Mg(2+) unveils the structural bases for the marginal role played by the ion in the nucleotide exchange process. Furthermore, nucleotide exchange experiments carried out on a truncated form of SsEF-1alpha, consisting only of the nucleotide binding domain, demonstrate that the low affinity of SsEF-1alpha.GDP for Mg(2+) is due to the local architecture of the active site and does not depend on the presence of the other two domains. Finally, considering the available structures of EF-1alpha, a detailed mechanism for the nucleotide exchange process has been traced. Notably, this mechanism involves residues such as His14, Arg95, Gln131, and Glu134, which are strictly conserved in all archaea and eukarya EF-1alpha sequences hitherto reported.

-	~~{{STRUCTURE_1skq\| PDB=1skq \| SCENE= }}~~	+	The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with magnesium and GDP.,Vitagliano L, Ruggiero A, Masullo M, Cantiello P, Arcari P, Zagari A Biochemistry. 2004 Jun 1;43(21):6630-6. PMID:15157096<ref>PMID:15157096</ref>

-	~~===The crystal structure~~ of ~~Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15157096}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1skq]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA].~~	+

	==See Also==		==See Also==
	*[[Elongation factor\|Elongation factor]]		*[[Elongation factor\|Elongation factor]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:015157096<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
	[[Category: Arcari, P.]]		[[Category: Arcari, P.]]

OCA: Protected "1skq" [edit=sysop:move=sysop]

2012-10-20T08:12:50Z

Protected "1skq" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:12, 20 October 2012

OCA at 08:12, 20 October 2012

2012-10-20T08:12:48Z

←Older revision		Revision as of 08:12, 20 October 2012
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-	{{Seed}}
	[[Image:1skq.png\|left\|200px]]		[[Image:1skq.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1skq", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_1skq\| PDB=1skq \| SCENE= }}		{{STRUCTURE_1skq\| PDB=1skq \| SCENE= }}

	===The crystal structure of Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP===		===The crystal structure of Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15157096}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15157096 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_15157096}}		{{ABSTRACT_PUBMED_15157096}}

	==About this Structure==		==About this Structure==
-	~~1SKQ~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA].	+	[[1skq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA].
		+
		+	==See Also==
		+	*[[Elongation factor\|Elongation factor]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15157096~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015157096</ref><references group="xtra"/>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
	[[Category: Arcari, P.]]		[[Category: Arcari, P.]]
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	[[Category: Elongation factor]]		[[Category: Elongation factor]]
	[[Category: Protein synthesis]]		[[Category: Protein synthesis]]
-		+	[[Category: Translation]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 17:18:24 2009''~~	+

OCA at 15:18, 16 February 2009

2009-02-16T15:18:26Z

←Older revision		Revision as of 15:18, 16 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1SKQ is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA].	+	1SKQ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SKQ OCA].

	==Reference==		==Reference==
-	The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with magnesium and GDP., Vitagliano L, Ruggiero A, Masullo M, Cantiello P, Arcari P, Zagari A, Biochemistry. 2004 Jun 1;43(21):6630-6. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/15157096 15157096]~~	+	<ref group="xtra">PMID:15157096</ref><references group="xtra"/>
-	~~[[Category: Single protein]]~~	+
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
	[[Category: Arcari, P.]]		[[Category: Arcari, P.]]
Line 36:		Line 35:
	[[Category: Protein synthesis]]		[[Category: Protein synthesis]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Jul 27 20~~:40:~~17 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:18:24 2009''