1sna - Revision history

OCA at 21:36, 28 June 2023

2023-06-28T21:36:24Z

←Older revision		Revision as of 21:36, 28 June 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1sna]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SNA FirstGlance]. <br>		<table><tr><td colspan='2'>[[1sna]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SNA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBZ:3-(BENZOYLAMINO)-L-ALANINE'>DBZ</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=~~MSO~~:~~SELENOMETHIONINE~~+~~SELENOXIDE~~'>~~MSO~~</scene>, <scene name='pdbligand=~~NH2~~:~~AMINO~~+~~GROUP~~'>~~NH2~~</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBZ:3-(BENZOYLAMINO)-L-ALANINE'>DBZ</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MSO:SELENOMETHIONINE+SELENOXIDE'>MSO</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;~~'>~~[[1sn9\|1sn9]], [[1sne\|1sne]]~~</~~div~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sna OCA], [https://pdbe.org/1sna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sna RCSB], [https://www.ebi.ac.uk/pdbsum/1sna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sna ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sna OCA], [https://pdbe.org/1sna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sna RCSB], [https://www.ebi.ac.uk/pdbsum/1sna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sna ProSAT]</span></td></tr>
	</table>		</table>
Line 23:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ali~~, M H~~]]	+	[[Category: Ali MH]]
-	[[Category: Allen~~, K N~~]]	+	[[Category: Allen KN]]
-	[[Category: Imperiali, B]]	+	[[Category: Imperiali B]]
-	[[Category: Peisach, E]]	+	[[Category: Peisach E]]
-	~~[[Category: De novo protein]]~~	+
-	~~[[Category: Domain swapping]]~~	+
-	~~[[Category: Mini-protein]]~~	+
-	~~[[Category: Oligomerization]]~~	+
-	~~[[Category: Protein design~~]]	+

OCA at 07:34, 22 September 2021

2021-09-22T07:34:33Z

←Older revision		Revision as of 07:34, 22 September 2021
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	<StructureSection load='1sna' size='340' side='right'caption='[[1sna]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='1sna' size='340' side='right'caption='[[1sna]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1sna]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1SNA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1sna]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SNA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBZ:3-(BENZOYLAMINO)-L-ALANINE'>DBZ</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=MSO:SELENOMETHIONINE+SELENOXIDE'>MSO</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBZ:3-(BENZOYLAMINO)-L-ALANINE'>DBZ</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=MSO:SELENOMETHIONINE+SELENOXIDE'>MSO</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sn9\|1sn9]], [[1sne\|1sne]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1sn9\|1sn9]], [[1sne\|1sne]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1sna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sna OCA], [~~http~~://pdbe.org/1sna PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1sna RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1sna PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1sna ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sna OCA], [https://pdbe.org/1sna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sna RCSB], [https://www.ebi.ac.uk/pdbsum/1sna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sna ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:18, 18 December 2019

2019-12-18T14:18:19Z

←Older revision		Revision as of 14:18, 18 December 2019
Line 1:		Line 1:

	==An Oligomeric Domain-Swapped Beta-Beta-Alpha Mini-Protein==		==An Oligomeric Domain-Swapped Beta-Beta-Alpha Mini-Protein==
-	<StructureSection load='1sna' size='340' side='right' caption='[[1sna]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='1sna' size='340' side='right'caption='[[1sna]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1sna]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SNA FirstGlance]. <br>		<table><tr><td colspan='2'>[[1sna]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SNA FirstGlance]. <br>
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Ali, M H]]		[[Category: Ali, M H]]
	[[Category: Allen, K N]]		[[Category: Allen, K N]]

OCA at 07:58, 14 March 2018

2018-03-14T07:58:30Z

←Older revision		Revision as of 07:58, 14 March 2018
Line 1:		Line 1:
		+
	==An Oligomeric Domain-Swapped Beta-Beta-Alpha Mini-Protein==		==An Oligomeric Domain-Swapped Beta-Beta-Alpha Mini-Protein==
	<StructureSection load='1sna' size='340' side='right' caption='[[1sna]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='1sna' size='340' side='right' caption='[[1sna]], [[Resolution\|resolution]] 1.50Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBZ:3-(BENZOYLAMINO)-L-ALANINE'>DBZ</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=MSO:SELENOMETHIONINE+SELENOXIDE'>MSO</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBZ:3-(BENZOYLAMINO)-L-ALANINE'>DBZ</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=MSO:SELENOMETHIONINE+SELENOXIDE'>MSO</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sn9\|1sn9]], [[1sne\|1sne]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sn9\|1sn9]], [[1sne\|1sne]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sna OCA], [http://pdbe.org/1sna PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sna RCSB], [http://www.ebi.ac.uk/pdbsum/1sna PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sna OCA], [http://pdbe.org/1sna PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sna RCSB], [http://www.ebi.ac.uk/pdbsum/1sna PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1sna ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:18, 11 September 2015

2015-09-11T01:18:02Z

←Older revision		Revision as of 01:18, 11 September 2015
Line 6:		Line 6:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBZ:3-(BENZOYLAMINO)-L-ALANINE'>DBZ</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=MSO:SELENOMETHIONINE+SELENOXIDE'>MSO</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBZ:3-(BENZOYLAMINO)-L-ALANINE'>DBZ</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=MSO:SELENOMETHIONINE+SELENOXIDE'>MSO</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sn9\|1sn9]], [[1sne\|1sne]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sn9\|1sn9]], [[1sne\|1sne]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sna OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sna RCSB], [http://www.ebi.ac.uk/pdbsum/1sna PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sna OCA], [http://pdbe.org/1sna PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sna RCSB], [http://www.ebi.ac.uk/pdbsum/1sna PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1sna" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:43, 22 December 2014

2014-12-22T06:43:24Z

←Older revision		Revision as of 06:43, 22 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1sna\| PDB=1sna \| SCENE= }}~~	+	==An Oligomeric Domain-Swapped Beta-Beta-Alpha Mini-Protein==
-	===An Oligomeric Domain-Swapped Beta-Beta-Alpha Mini-Protein===	+	<StructureSection load='1sna' size='340' side='right' caption='[[1sna]], [[Resolution\|resolution]] 1.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_15302930}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1sna]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SNA FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBZ:3-(BENZOYLAMINO)-L-ALANINE'>DBZ</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=MSO:SELENOMETHIONINE+SELENOXIDE'>MSO</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sn9\|1sn9]], [[1sne\|1sne]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sna OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sna RCSB], [http://www.ebi.ac.uk/pdbsum/1sna PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The x-ray crystal structure of an oligomeric miniprotein has been determined to a 1.2-A resolution by means of multiwavelength anomalous diffraction phasing with selenomethionine analogs that retain the biophysical characteristics of the native peptide. Peptide 1, comprising alpha and beta secondary structure elements with only 21 aa per monomer, associates as a discrete tetramer. The peptide adopts a previously uncharacterized quaternary structure in which alpha and beta components interact to form a tightly packed and well defined hydrophobic core. The structure provides insight into the origins of the unusual thermal stability of the oligomer. The miniprotein shares many characteristics of larger proteins, including cooperative folding, lack of 1-anilino-8-naphthalene sulfonate binding, and limited deuterium exchange, and possesses a buried surface area typical of native proteins.

-	~~==About this Structure==~~	+	X-ray structure analysis of a designed oligomeric miniprotein reveals a discrete quaternary architecture.,Ali MH, Peisach E, Allen KN, Imperiali B Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12183-8. Epub 2004 Aug 9. PMID:15302930<ref>PMID:15302930</ref>
-	~~[[1sna]] is a 4 chain~~ structure. ~~Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=1SNA OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:015302930</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
-	[[Category: Ali, M H.]]	+	== References ==
-	[[Category: Allen, K N.]]	+	<references/>
-	[[Category: Imperiali, B.]]	+	__TOC__
-	[[Category: Peisach, E.]]	+	</StructureSection>
		+	[[Category: Ali, M H]]
		+	[[Category: Allen, K N]]
		+	[[Category: Imperiali, B]]
		+	[[Category: Peisach, E]]
	[[Category: De novo protein]]		[[Category: De novo protein]]
	[[Category: Domain swapping]]		[[Category: Domain swapping]]

OCA at 08:36, 23 April 2014

2014-04-23T08:36:22Z

←Older revision		Revision as of 08:36, 23 April 2014
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-	[[Image:1sna.png\|left\|200px]]
-
-	<!--
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-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1sna\| PDB=1sna \| SCENE= }}		{{STRUCTURE_1sna\| PDB=1sna \| SCENE= }}
-
	===An Oligomeric Domain-Swapped Beta-Beta-Alpha Mini-Protein===		===An Oligomeric Domain-Swapped Beta-Beta-Alpha Mini-Protein===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15302930}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15302930 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_15302930}}		{{ABSTRACT_PUBMED_15302930}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:015302930</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015302930</ref><references group="xtra"/><references/>
	[[Category: Ali, M H.]]		[[Category: Ali, M H.]]
	[[Category: Allen, K N.]]		[[Category: Allen, K N.]]

OCA: Protected "1sna" [edit=sysop:move=sysop]

2011-11-16T11:07:08Z

Protected "1sna" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:07, 16 November 2011

OCA at 11:07, 16 November 2011

2011-11-16T11:07:06Z

←Older revision		Revision as of 11:07, 16 November 2011
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1sna.png\|left\|200px]]		[[Image:1sna.png\|left\|200px]]

Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNA OCA].	+	[[1sna]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNA OCA].

	==Reference==		==Reference==
-	X-ray structure analysis of a designed oligomeric miniprotein reveals a discrete quaternary architecture., Ali MH, Peisach E, Allen KN, Imperiali B, Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12183-8. Epub 2004 Aug 9. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~15302930 15302930]~~	+	<ref group="xtra">PMID:015302930</ref><references group="xtra"/>
	[[Category: Ali, M H.]]		[[Category: Ali, M H.]]
	[[Category: Allen, K N.]]		[[Category: Allen, K N.]]
	[[Category: Imperiali, B.]]		[[Category: Imperiali, B.]]
	[[Category: Peisach, E.]]		[[Category: Peisach, E.]]
		+	[[Category: De novo protein]]
	[[Category: Domain swapping]]		[[Category: Domain swapping]]
	[[Category: Mini-protein]]		[[Category: Mini-protein]]
	[[Category: Oligomerization]]		[[Category: Oligomerization]]
	[[Category: Protein design]]		[[Category: Protein design]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:24:45 2008''

OCA at 13:24, 28 July 2008

2008-07-28T13:24:46Z

←Older revision		Revision as of 13:24, 28 July 2008
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-	[[Image:1sna.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:1sna.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_1sna\| PDB=1sna \| SCENE= }}		{{STRUCTURE_1sna\| PDB=1sna \| SCENE= }}

-	~~'''~~An Oligomeric Domain-Swapped Beta-Beta-Alpha Mini-Protein~~'''~~	+	===An Oligomeric Domain-Swapped Beta-Beta-Alpha Mini-Protein===


-	~~==Overview==~~	+	<!--
-	The ~~x-ray crystal structure of an oligomeric miniprotein has been determined~~ to ~~a 1.2-A resolution by means of multiwavelength anomalous diffraction phasing with selenomethionine analogs that retain~~ the ~~biophysical characteristics of the native peptide. Peptide 1, comprising alpha and beta secondary structure elements with only 21 aa per monomer, associates~~ as ~~a discrete tetramer~~. ~~The peptide adopts a previously uncharacterized quaternary structure in which alpha and beta components interact to form a tightly packed and well defined hydrophobic core~~. ~~The structure provides insight into~~ the ~~origins of the unusual thermal stability of the oligomer~~. ~~The miniprotein shares many characteristics of larger proteins, including cooperative folding, lack of 1~~-~~anilino~~-~~8-naphthalene sulfonate binding, and limited deuterium exchange, and possesses a buried surface area typical of native proteins.~~	+	The line below this paragraph, {{ABSTRACT_PUBMED_15302930}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 15302930 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_15302930}}

	==About this Structure==		==About this Structure==
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	[[Category: Oligomerization]]		[[Category: Oligomerization]]
	[[Category: Protein design]]		[[Category: Protein design]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 08~~:54:59 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:24:45 2008''