1uc7 - Revision history

OCA at 23:50, 27 December 2023

2023-12-27T23:50:43Z

←Older revision		Revision as of 23:50, 27 December 2023
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	<StructureSection load='1uc7' size='340' side='right'caption='[[1uc7]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1uc7' size='340' side='right'caption='[[1uc7]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>
-	</td></tr><tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"~~><span class~~=~~'plainlinks'~~>~~[https://en.wikipedia.org/wiki/Protein~~-~~disulfide_reductase Protein-disulfide reductase]~~, ~~with EC number~~ [~~https://www.brenda-enzymes.info/php/result_flat.php4?ecno=~~1.~~8.1.8 1.8.1.8] </span>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc7 OCA], [https://pdbe.org/1uc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uc7 RCSB], [https://www.ebi.ac.uk/pdbsum/1uc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uc7 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc7 OCA], [https://pdbe.org/1uc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uc7 RCSB], [https://www.ebi.ac.uk/pdbsum/1uc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uc7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/DSBD_ECO57 DSBD_ECO57]] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).	+	[https://www.uniprot.org/uniprot/DSBD_ECO57 DSBD_ECO57] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Protein-disulfide reductase]]~~	+	[[Category: Jeong DG]]
-	[[Category: Jeong~~, D G~~]]	+	[[Category: Kim JH]]
-	[[Category: Kim~~, J H~~]]	+	[[Category: Kim SJ]]
-	[[Category: Kim~~, S J~~]]	+	[[Category: Ryu SE]]
-	[[Category: Ryu~~, S E~~]]	+	[[Category: Son JH]]
-	[[Category: Son~~, J H]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Thioredoxin-fold~~]]	+

OCA at 09:39, 29 September 2021

2021-09-29T09:39:48Z

←Older revision		Revision as of 09:39, 29 September 2021
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	<StructureSection load='1uc7' size='340' side='right'caption='[[1uc7]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1uc7' size='340' side='right'caption='[[1uc7]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>
-	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1uc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc7 OCA], [~~http~~://pdbe.org/1uc7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1uc7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1uc7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1uc7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc7 OCA], [https://pdbe.org/1uc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uc7 RCSB], [https://www.ebi.ac.uk/pdbsum/1uc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uc7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DSBD_ECO57 DSBD_ECO57]] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).	+	[[https://www.uniprot.org/uniprot/DSBD_ECO57 DSBD_ECO57]] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Thiol:disulfide interchange protein\|Thiol:disulfide interchange protein]]	+	*[[Thiol:disulfide interchange protein 3D structures\|Thiol:disulfide interchange protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:39, 25 December 2019

2019-12-25T13:39:13Z

←Older revision		Revision as of 13:39, 25 December 2019
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	==Crystal structure of DsbDgamma==		==Crystal structure of DsbDgamma==
-	<StructureSection load='1uc7' size='340' side='right' caption='[[1uc7]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='1uc7' size='340' side='right'caption='[[1uc7]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Protein-disulfide reductase]]		[[Category: Protein-disulfide reductase]]
	[[Category: Jeong, D G]]		[[Category: Jeong, D G]]

OCA at 08:30, 21 March 2018

2018-03-21T08:30:11Z

←Older revision		Revision as of 08:30, 21 March 2018
Line 1:		Line 1:
		+
	==Crystal structure of DsbDgamma==		==Crystal structure of DsbDgamma==
	<StructureSection load='1uc7' size='340' side='right' caption='[[1uc7]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1uc7' size='340' side='right' caption='[[1uc7]], [[Resolution\|resolution]] 1.90Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc7 OCA], [http://pdbe.org/1uc7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uc7 RCSB], [http://www.ebi.ac.uk/pdbsum/1uc7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc7 OCA], [http://pdbe.org/1uc7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uc7 RCSB], [http://www.ebi.ac.uk/pdbsum/1uc7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1uc7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uc/1uc7_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uc/1uc7_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 01:07, 10 February 2016

2016-02-10T01:07:02Z

←Older revision		Revision as of 01:07, 10 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uc7 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 03:51, 11 September 2015

2015-09-11T03:51:21Z

←Older revision		Revision as of 03:51, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1uc7' size='340' side='right' caption='[[1uc7]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1uc7' size='340' side='right' caption='[[1uc7]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uc7 RCSB], [http://www.ebi.ac.uk/pdbsum/1uc7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc7 OCA], [http://pdbe.org/1uc7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uc7 RCSB], [http://www.ebi.ac.uk/pdbsum/1uc7 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1uc7" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Thiol:disulfide interchange protein\|Thiol:disulfide interchange protein]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Protein-disulfide reductase]]		[[Category: Protein-disulfide reductase]]
	[[Category: Jeong, D G]]		[[Category: Jeong, D G]]

OCA at 10:43, 25 December 2014

2014-12-25T10:43:29Z

←Older revision		Revision as of 10:43, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uc7 RCSB], [http://www.ebi.ac.uk/pdbsum/1uc7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uc7 RCSB], [http://www.ebi.ac.uk/pdbsum/1uc7 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DSBD_ECO57 DSBD_ECO57]] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Protein-disulfide reductase]]		[[Category: Protein-disulfide reductase]]
-	[[Category: Jeong, D G.]]	+	[[Category: Jeong, D G]]
-	[[Category: Kim, J H.]]	+	[[Category: Kim, J H]]
-	[[Category: Kim, S J.]]	+	[[Category: Kim, S J]]
-	[[Category: Ryu, S E.]]	+	[[Category: Ryu, S E]]
-	[[Category: Son, J H.]]	+	[[Category: Son, J H]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Thioredoxin-fold]]		[[Category: Thioredoxin-fold]]

OCA at 21:47, 29 September 2014

2014-09-29T21:47:19Z

←Older revision		Revision as of 21:47, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1uc7.~~png\|left~~\|200px]]	+	==Crystal structure of DsbDgamma==
		+	<StructureSection load='1uc7' size='340' side='right' caption='[[1uc7]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1uc7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UC7 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uc7 RCSB], [http://www.ebi.ac.uk/pdbsum/1uc7 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uc/1uc7_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Escherichia coli transmembrane protein DsbD transfers electrons from the cytoplasm to the periplasm through a cascade of thiol-disulfide exchange reactions. In this process, the C-terminal periplasmic domain of DsbD (DsbDgamma) shuttles the reducing potential from the membrane domain (DsbDbeta) to the N-terminal periplasmic domain (DsbDalpha). The crystal structure of DsbDgamma determined at 1.9 A resolution reveals that the domain has a thioredoxin fold with an extended N-terminal stretch. In comparison to thioredoxin, the DsbDgamma structure exhibits the stabilized active site conformation and the extended active site alpha2 helix that explain the domain's substrate specificity and the redox potential shift, respectively. The hypothetical model of the DsbDgamma:DsbDalpha complex based on the DsbDgamma structure and previous structural studies indicates that the conserved hydrophobic residue in the C-X-X-C motif of DsbDgamma may be important in the specific recognition of DsbDalpha.

-	~~{{STRUCTURE_1uc7\| PDB=1uc7 \| SCENE= }}~~	+	Crystal structure of DsbDgamma reveals the mechanism of redox potential shift and substrate specificity(1).,Kim JH, Kim SJ, Jeong DG, Son JH, Ryu SE FEBS Lett. 2003 May 22;543(1-3):164-9. PMID:12753926<ref>PMID:12753926</ref>

-	~~===Crystal structure~~ of ~~DsbDgamma===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12753926}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1uc7]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:012753926<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Protein-disulfide reductase]]		[[Category: Protein-disulfide reductase]]

OCA: Protected "1uc7" [edit=sysop:move=sysop]

2013-01-05T13:16:21Z

Protected "1uc7" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:16, 5 January 2013

OCA at 13:16, 5 January 2013

2013-01-05T13:16:18Z

←Older revision		Revision as of 13:16, 5 January 2013
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-	{{Seed}}
	[[Image:1uc7.png\|left\|200px]]		[[Image:1uc7.png\|left\|200px]]

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	{{STRUCTURE_1uc7\| PDB=1uc7 \| SCENE= }}		{{STRUCTURE_1uc7\| PDB=1uc7 \| SCENE= }}

	===Crystal structure of DsbDgamma===		===Crystal structure of DsbDgamma===

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	{{ABSTRACT_PUBMED_12753926}}		{{ABSTRACT_PUBMED_12753926}}

	==About this Structure==		==About this Structure==
-	~~1UC7~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA].	+	[[1uc7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC7 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12753926~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012753926</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Protein-disulfide reductase]]		[[Category: Protein-disulfide reductase]]
Line 31:		Line 19:
	[[Category: Ryu, S E.]]		[[Category: Ryu, S E.]]
	[[Category: Son, J H.]]		[[Category: Son, J H.]]
		+	[[Category: Oxidoreductase]]
	[[Category: Thioredoxin-fold]]		[[Category: Thioredoxin-fold]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:11:43 2009''