1ukf - Revision history

OCA at 23:55, 27 December 2023

2023-12-27T23:55:09Z

←Older revision		Revision as of 23:55, 27 December 2023
Line 3:		Line 3:
	<StructureSection load='1ukf' size='340' side='right'caption='[[1ukf]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='1ukf' size='340' side='right'caption='[[1ukf]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Psesh Psesh~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UKF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_savastanoi_pv._phaseolicola Pseudomonas savastanoi pv. phaseolicola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UKF FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ukf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ukf OCA], [https://pdbe.org/1ukf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ukf RCSB], [https://www.ebi.ac.uk/pdbsum/1ukf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ukf ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.35Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ukf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ukf OCA], [https://pdbe.org/1ukf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ukf RCSB], [https://www.ebi.ac.uk/pdbsum/1ukf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ukf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/AVRP3_PSESH AVRP3_PSESH]] Cysteine protease avirulence protein, which is essential during infection of plant cells from cultivar-specific of beans and Arabidopsis thaliana. The autocleavage of the protein is required for virulence function. May act by affecting the plant defense system. In plants lacking R3 or RPS5 resistance genes, it probably impairs the plant defense system and leads to the bacteria multiplication. In contrast, in plants containing the R3 or RPS5 protein, it is unable to induce disease symptoms, explaining its avirulence name. The 7 kDa product is required for the type-III translocation from Pseudomonas strains to the plant, but are partially dispensable for effector recognition following in planta expression. In infected plants, it probably acts by cleaving the PBS1 protein, which may lead to resistance or disease, depending on the presence or absence of RPS5, respectively.<ref>PMID:11952132</ref>	+	[https://www.uniprot.org/uniprot/AVRP3_PSESH AVRP3_PSESH] Cysteine protease avirulence protein, which is essential during infection of plant cells from cultivar-specific of beans and Arabidopsis thaliana. The autocleavage of the protein is required for virulence function. May act by affecting the plant defense system. In plants lacking R3 or RPS5 resistance genes, it probably impairs the plant defense system and leads to the bacteria multiplication. In contrast, in plants containing the R3 or RPS5 protein, it is unable to induce disease symptoms, explaining its avirulence name. The 7 kDa product is required for the type-III translocation from Pseudomonas strains to the plant, but are partially dispensable for effector recognition following in planta expression. In infected plants, it probably acts by cleaving the PBS1 protein, which may lead to resistance or disease, depending on the presence or absence of RPS5, respectively.<ref>PMID:11952132</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Psesh~~]]	+	[[Category: Pseudomonas savastanoi pv. phaseolicola]]
-	[[Category: Dixon~~, J E~~]]	+	[[Category: Dixon JE]]
-	[[Category: Innes~~, R W~~]]	+	[[Category: Innes RW]]
-	[[Category: Shao, F]]	+	[[Category: Shao F]]
-	[[Category: Xu, Z]]	+	[[Category: Xu Z]]
-	[[Category: Zhu, M]]	+	[[Category: Zhu M]]
-	~~[[Category: Avirulence]]~~	+
-	~~[[Category: Avrpph3]]~~	+
-	~~[[Category: Avrpphb]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Hypersensitive response~~]]	+

OCA at 06:12, 6 October 2021

2021-10-06T06:12:21Z

←Older revision		Revision as of 06:12, 6 October 2021
Line 3:		Line 3:
	<StructureSection load='1ukf' size='340' side='right'caption='[[1ukf]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='1ukf' size='340' side='right'caption='[[1ukf]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Psesh Psesh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1UKF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Psesh Psesh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UKF FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ukf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ukf OCA], [~~http~~://pdbe.org/1ukf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ukf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ukf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ukf ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ukf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ukf OCA], [https://pdbe.org/1ukf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ukf RCSB], [https://www.ebi.ac.uk/pdbsum/1ukf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ukf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/AVRP3_PSESH AVRP3_PSESH]] Cysteine protease avirulence protein, which is essential during infection of plant cells from cultivar-specific of beans and Arabidopsis thaliana. The autocleavage of the protein is required for virulence function. May act by affecting the plant defense system. In plants lacking R3 or RPS5 resistance genes, it probably impairs the plant defense system and leads to the bacteria multiplication. In contrast, in plants containing the R3 or RPS5 protein, it is unable to induce disease symptoms, explaining its avirulence name. The 7 kDa product is required for the type-III translocation from Pseudomonas strains to the plant, but are partially dispensable for effector recognition following in planta expression. In infected plants, it probably acts by cleaving the PBS1 protein, which may lead to resistance or disease, depending on the presence or absence of RPS5, respectively.<ref>PMID:11952132</ref>	+	[[https://www.uniprot.org/uniprot/AVRP3_PSESH AVRP3_PSESH]] Cysteine protease avirulence protein, which is essential during infection of plant cells from cultivar-specific of beans and Arabidopsis thaliana. The autocleavage of the protein is required for virulence function. May act by affecting the plant defense system. In plants lacking R3 or RPS5 resistance genes, it probably impairs the plant defense system and leads to the bacteria multiplication. In contrast, in plants containing the R3 or RPS5 protein, it is unable to induce disease symptoms, explaining its avirulence name. The 7 kDa product is required for the type-III translocation from Pseudomonas strains to the plant, but are partially dispensable for effector recognition following in planta expression. In infected plants, it probably acts by cleaving the PBS1 protein, which may lead to resistance or disease, depending on the presence or absence of RPS5, respectively.<ref>PMID:11952132</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 13:02, 1 January 2020

2020-01-01T13:02:57Z

←Older revision		Revision as of 13:02, 1 January 2020
Line 1:		Line 1:

	==Crystal Structure of Pseudomonas Avirulence Protein AvrPphB==		==Crystal Structure of Pseudomonas Avirulence Protein AvrPphB==
-	<StructureSection load='1ukf' size='340' side='right' caption='[[1ukf]], [[Resolution\|resolution]] 1.35Å' scene=''>	+	<StructureSection load='1ukf' size='340' side='right'caption='[[1ukf]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psesh Psesh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UKF FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psesh Psesh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UKF FirstGlance]. <br>
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Avirulence protein\|Avirulence protein]]	+	*[[Avirulence protein 3D structures\|Avirulence protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Psesh]]		[[Category: Psesh]]
	[[Category: Dixon, J E]]		[[Category: Dixon, J E]]

OCA at 07:52, 28 March 2018

2018-03-28T07:52:03Z

←Older revision		Revision as of 07:52, 28 March 2018
Line 1:		Line 1:
		+
	==Crystal Structure of Pseudomonas Avirulence Protein AvrPphB==		==Crystal Structure of Pseudomonas Avirulence Protein AvrPphB==
	<StructureSection load='1ukf' size='340' side='right' caption='[[1ukf]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='1ukf' size='340' side='right' caption='[[1ukf]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psesh Psesh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UKF FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psesh Psesh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UKF FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ukf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ukf OCA], [http://pdbe.org/1ukf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ukf RCSB], [http://www.ebi.ac.uk/pdbsum/1ukf PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ukf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ukf OCA], [http://pdbe.org/1ukf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ukf RCSB], [http://www.ebi.ac.uk/pdbsum/1ukf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ukf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uk/1ukf_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uk/1ukf_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ukf ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:30, 11 September 2015

2015-09-11T08:30:45Z

←Older revision		Revision as of 08:30, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1ukf' size='340' side='right' caption='[[1ukf]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='1ukf' size='340' side='right' caption='[[1ukf]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_syringae_pv._phaseolicola Pseudomonas syringae pv. phaseolicola~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UKF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psesh Psesh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UKF FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ukf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ukf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ukf RCSB], [http://www.ebi.ac.uk/pdbsum/1ukf PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ukf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ukf OCA], [http://pdbe.org/1ukf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ukf RCSB], [http://www.ebi.ac.uk/pdbsum/1ukf PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ukf" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pseudomonas syringae pv. phaseolicola~~]]	+	[[Category: Psesh]]
	[[Category: Dixon, J E]]		[[Category: Dixon, J E]]
	[[Category: Innes, R W]]		[[Category: Innes, R W]]

OCA at 13:53, 25 December 2014

2014-12-25T13:53:59Z

←Older revision		Revision as of 13:53, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._phaseolicola Pseudomonas syringae pv. phaseolicola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UKF FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._phaseolicola Pseudomonas syringae pv. phaseolicola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UKF FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ukf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ukf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ukf RCSB], [http://www.ebi.ac.uk/pdbsum/1ukf PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ukf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ukf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ukf RCSB], [http://www.ebi.ac.uk/pdbsum/1ukf PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AVRP3_PSESH AVRP3_PSESH]] Cysteine protease avirulence protein, which is essential during infection of plant cells from cultivar-specific of beans and Arabidopsis thaliana. The autocleavage of the protein is required for virulence function. May act by affecting the plant defense system. In plants lacking R3 or RPS5 resistance genes, it probably impairs the plant defense system and leads to the bacteria multiplication. In contrast, in plants containing the R3 or RPS5 protein, it is unable to induce disease symptoms, explaining its avirulence name. The 7 kDa product is required for the type-III translocation from Pseudomonas strains to the plant, but are partially dispensable for effector recognition following in planta expression. In infected plants, it probably acts by cleaving the PBS1 protein, which may lead to resistance or disease, depending on the presence or absence of RPS5, respectively.<ref>PMID:11952132</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Pseudomonas syringae pv. phaseolicola]]		[[Category: Pseudomonas syringae pv. phaseolicola]]
-	[[Category: Dixon, J E.]]	+	[[Category: Dixon, J E]]
-	[[Category: Innes, R W.]]	+	[[Category: Innes, R W]]
-	[[Category: Shao, F.]]	+	[[Category: Shao, F]]
-	[[Category: Xu, Z.]]	+	[[Category: Xu, Z]]
-	[[Category: Zhu, M.]]	+	[[Category: Zhu, M]]
	[[Category: Avirulence]]		[[Category: Avirulence]]
	[[Category: Avrpph3]]		[[Category: Avrpph3]]

OCA at 20:57, 29 September 2014

2014-09-29T20:57:26Z

←Older revision		Revision as of 20:57, 29 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1ukf\| PDB=1ukf \| SCENE= }}~~	+	==Crystal Structure of Pseudomonas Avirulence Protein AvrPphB==
-	===Crystal Structure of Pseudomonas Avirulence Protein AvrPphB===	+	<StructureSection load='1ukf' size='340' side='right' caption='[[1ukf]], [[Resolution\|resolution]] 1.35Å' scene=''>
-	~~{{ABSTRACT_PUBMED_14694194}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ukf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._phaseolicola Pseudomonas syringae pv. phaseolicola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UKF FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ukf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ukf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ukf RCSB], [http://www.ebi.ac.uk/pdbsum/1ukf PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uk/1ukf_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	AvrPphB is an avirulence (Avr) protein from the plant pathogen Pseudomonas syringae that can trigger a disease-resistance response in a number of host plants including Arabidopsis. AvrPphB belongs to a novel family of cysteine proteases with the charter member of this family being the Yersinia effector protein YopT. AvrPphB has a very stringent substrate specificity, catalyzing a single proteolytic cleavage in the Arabidopsis serine/threonine kinase PBS1. We have determined the crystal structure of AvrPphB by x-ray crystallography at 1.35-A resolution. The structure is composed of a central antiparallel beta-sheet, with alpha-helices packing on both sides of the sheet to form a two-lobe structure. The core of this structure resembles the papain-like cysteine proteases. The similarity includes the AvrPphB active site catalytic triad of Cys-98, His-212, and Asp-227 and the oxyanion hole residue Asn-93. Based on analogy with inhibitor complexes of the papain-like proteases, we propose a model for the substrate-binding mechanism of AvrPphB. A deep and positively charged pocket (S2) and a neighboring shallow surface (S3) likely bind to aspartic acid and glycine residues in the substrate located two (P2) and three (P3) residues N terminal to the cleavage site, respectively. Further implications about the specificity of plant pathogen recognition are also discussed.

-	~~==About this Structure==~~	+	The crystal structure of Pseudomonas avirulence protein AvrPphB: a papain-like fold with a distinct substrate-binding site.,Zhu M, Shao F, Innes RW, Dixon JE, Xu Z Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):302-7. Epub 2003 Dec 23. PMID:14694194<ref>PMID:14694194</ref>
-	~~[[1ukf]] is a 1 chain~~ structure ~~with sequence from [http~~:~~//en~~.~~wikipedia~~.~~org/wiki/Pseudomonas_syringae_pv~~.~~_phaseolicola Pseudomonas syringae pv. phaseolicola]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=1UKF OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Avirulence protein\|Avirulence protein]]		*[[Avirulence protein\|Avirulence protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:014694194<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Pseudomonas syringae pv. phaseolicola]]		[[Category: Pseudomonas syringae pv. phaseolicola]]
	[[Category: Dixon, J E.]]		[[Category: Dixon, J E.]]

OCA at 09:54, 11 March 2013

2013-03-11T09:54:22Z

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-	[[Image:1ukf.png\|left\|200px]]
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	{{STRUCTURE_1ukf\| PDB=1ukf \| SCENE= }}		{{STRUCTURE_1ukf\| PDB=1ukf \| SCENE= }}
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	===Crystal Structure of Pseudomonas Avirulence Protein AvrPphB===		===Crystal Structure of Pseudomonas Avirulence Protein AvrPphB===
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	{{ABSTRACT_PUBMED_14694194}}		{{ABSTRACT_PUBMED_14694194}}

OCA: Protected "1ukf" [edit=sysop:move=sysop]

2013-01-05T11:55:01Z

Protected "1ukf" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:55, 5 January 2013

OCA at 11:54, 5 January 2013

2013-01-05T11:54:59Z

←Older revision		Revision as of 11:54, 5 January 2013
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-	{{Seed}}
	[[Image:1ukf.png\|left\|200px]]		[[Image:1ukf.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1ukf\| PDB=1ukf \| SCENE= }}		{{STRUCTURE_1ukf\| PDB=1ukf \| SCENE= }}

	===Crystal Structure of Pseudomonas Avirulence Protein AvrPphB===		===Crystal Structure of Pseudomonas Avirulence Protein AvrPphB===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_14694194}}, adds the Publication Abstract to the page
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	{{ABSTRACT_PUBMED_14694194}}		{{ABSTRACT_PUBMED_14694194}}

	==About this Structure==		==About this Structure==
-	~~1UKF~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._phaseolicola Pseudomonas syringae pv. phaseolicola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA].	+	[[1ukf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._phaseolicola Pseudomonas syringae pv. phaseolicola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UKF OCA].
		+
		+	==See Also==
		+	*[[Avirulence protein\|Avirulence protein]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~14694194~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:014694194</ref><references group="xtra"/>
	[[Category: Pseudomonas syringae pv. phaseolicola]]		[[Category: Pseudomonas syringae pv. phaseolicola]]
	[[Category: Dixon, J E.]]		[[Category: Dixon, J E.]]
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	[[Category: Avrpph3]]		[[Category: Avrpph3]]
	[[Category: Avrpphb]]		[[Category: Avrpphb]]
		+	[[Category: Hydrolase]]
	[[Category: Hypersensitive response]]		[[Category: Hypersensitive response]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:57:52 2009''