1urp - Revision history

OCA at 08:45, 14 February 2024

2024-02-14T08:45:50Z

←Older revision		Revision as of 08:45, 14 February 2024
Line 3:		Line 3:
	<StructureSection load='1urp' size='340' side='right'caption='[[1urp]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1urp' size='340' side='right'caption='[[1urp]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1URP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1URP FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1urp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urp OCA], [https://pdbe.org/1urp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1urp RCSB], [https://www.ebi.ac.uk/pdbsum/1urp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1urp ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1urp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urp OCA], [https://pdbe.org/1urp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1urp RCSB], [https://www.ebi.ac.uk/pdbsum/1urp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1urp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/RBSB_ECOLI RBSB_ECOLI]] Involved in the high-affinity D-ribose membrane transport system and also serves as the primary chemoreceptor for chemotaxis.	+	[https://www.uniprot.org/uniprot/RBSB_ECOLI RBSB_ECOLI] Involved in the high-affinity D-ribose membrane transport system and also serves as the primary chemoreceptor for chemotaxis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1urp ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1urp ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Conformational changes are necessary for the function of bacterial periplasmic receptors in chemotaxis and transport. Such changes allow entry and exit of ligand, and enable the correct interaction of the ligand-bound proteins with the membrane components of each system. Three open, ligand-free forms of the Escherichia coli ribose-binding protein were observed here by X-ray crystallographic studies. They are opened by 43 degrees, 50 degrees and 64 degrees with respect to the ligand-bound protein reported previously. The three open forms are not distinct, but show a clear relationship to each other. All are the product of a similar opening motion, and are stabilized by a new, almost identical packing interface between the domains. The changes are generated by similar bond rotations, although some differences in the three hinge segments are needed to accommodate the various structural scenarios. Some local repacking also occurs as interdomain contacts are lost. The least open (43 degrees) form is probably the dominant one in solution under normal conditions, although a mixture of species seems likely. The open and closed forms have distinct surfaces in the regions known to be important in chemotaxis and transport, which will differentiate their interactions with the membrane components. It seems certain that the conformational path that links the forms described here is that followed during ligand retrieval, and in ligand release into the membrane-bound permease system.
-
-	Multiple open forms of ribose-binding protein trace the path of its conformational change.,Bjorkman AJ, Mowbray SL J Mol Biol. 1998 Jun 12;279(3):651-64. PMID:9641984<ref>PMID:9641984</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1urp" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Ribose-binding protein\|Ribose-binding protein]]		*[[Ribose-binding protein\|Ribose-binding protein]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bjorkman~~, A J~~]]	+	[[Category: Bjorkman AJ]]
-	[[Category: Mowbray~~, S L]]~~	+	[[Category: Mowbray SL]]
-	~~[[Category: Chemotaxis]]~~	+
-	~~[[Category: Periplasm]]~~	+
-	~~[[Category: Transport~~]]	+

OCA at 06:16, 6 October 2021

2021-10-06T06:16:55Z

←Older revision		Revision as of 06:16, 6 October 2021
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	<StructureSection load='1urp' size='340' side='right'caption='[[1urp]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1urp' size='340' side='right'caption='[[1urp]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1URP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1URP FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1urp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urp OCA], [~~http~~://pdbe.org/1urp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1urp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1urp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1urp ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1urp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urp OCA], [https://pdbe.org/1urp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1urp RCSB], [https://www.ebi.ac.uk/pdbsum/1urp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1urp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RBSB_ECOLI RBSB_ECOLI]] Involved in the high-affinity D-ribose membrane transport system and also serves as the primary chemoreceptor for chemotaxis.	+	[[https://www.uniprot.org/uniprot/RBSB_ECOLI RBSB_ECOLI]] Involved in the high-affinity D-ribose membrane transport system and also serves as the primary chemoreceptor for chemotaxis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Molecular Playground/RBP\|Molecular Playground/RBP]]
	*[[Ribose-binding protein\|Ribose-binding protein]]		*[[Ribose-binding protein\|Ribose-binding protein]]
	== References ==		== References ==

OCA at 13:04, 1 January 2020

2020-01-01T13:04:50Z

←Older revision		Revision as of 13:04, 1 January 2020
Line 1:		Line 1:

	==D-RIBOSE-BINDING PROTEIN FROM ESCHERICHIA COLI==		==D-RIBOSE-BINDING PROTEIN FROM ESCHERICHIA COLI==
-	<StructureSection load='1urp' size='340' side='right' caption='[[1urp]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='1urp' size='340' side='right'caption='[[1urp]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1URP FirstGlance]. <br>		<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1URP FirstGlance]. <br>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Ecoli]]		[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Bjorkman, A J]]		[[Category: Bjorkman, A J]]
	[[Category: Mowbray, S L]]		[[Category: Mowbray, S L]]

OCA at 07:54, 28 March 2018

2018-03-28T07:54:13Z

←Older revision		Revision as of 07:54, 28 March 2018
Line 1:		Line 1:
		+
	==D-RIBOSE-BINDING PROTEIN FROM ESCHERICHIA COLI==		==D-RIBOSE-BINDING PROTEIN FROM ESCHERICHIA COLI==
	<StructureSection load='1urp' size='340' side='right' caption='[[1urp]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1urp' size='340' side='right' caption='[[1urp]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1URP FirstGlance]. <br>		<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1URP FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1urp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urp OCA], [http://pdbe.org/1urp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1urp RCSB], [http://www.ebi.ac.uk/pdbsum/1urp PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1urp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urp OCA], [http://pdbe.org/1urp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1urp RCSB], [http://www.ebi.ac.uk/pdbsum/1urp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1urp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ur/1urp_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ur/1urp_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 38:		Line 39:
	[[Category: Mowbray, S L]]		[[Category: Mowbray, S L]]
	[[Category: Chemotaxis]]		[[Category: Chemotaxis]]
		+	[[Category: Periplasm]]
	[[Category: Transport]]		[[Category: Transport]]

OCA at 04:51, 10 February 2016

2016-02-10T04:51:38Z

←Older revision		Revision as of 04:51, 10 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1urp ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:33, 11 September 2015

2015-09-11T05:33:38Z

←Older revision		Revision as of 05:33, 11 September 2015
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	<StructureSection load='1urp' size='340' side='right' caption='[[1urp]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1urp' size='340' side='right' caption='[[1urp]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli_k-12 Escherichia coli k-12~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1URP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1URP FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1urp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1urp RCSB], [http://www.ebi.ac.uk/pdbsum/1urp PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1urp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urp OCA], [http://pdbe.org/1urp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1urp RCSB], [http://www.ebi.ac.uk/pdbsum/1urp PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1urp" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia coli k-12~~]]	+	[[Category: Ecoli]]
	[[Category: Bjorkman, A J]]		[[Category: Bjorkman, A J]]
	[[Category: Mowbray, S L]]		[[Category: Mowbray, S L]]
	[[Category: Chemotaxis]]		[[Category: Chemotaxis]]
	[[Category: Transport]]		[[Category: Transport]]

OCA at 11:54, 25 December 2014

2014-12-25T11:54:27Z

←Older revision		Revision as of 11:54, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1URP FirstGlance]. <br>		<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1URP FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1urp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1urp RCSB], [http://www.ebi.ac.uk/pdbsum/1urp PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1urp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1urp RCSB], [http://www.ebi.ac.uk/pdbsum/1urp PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RBSB_ECOLI RBSB_ECOLI]] Involved in the high-affinity D-ribose membrane transport system and also serves as the primary chemoreceptor for chemotaxis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
-	[[Category: Bjorkman, A J.]]	+	[[Category: Bjorkman, A J]]
-	[[Category: Mowbray, S L.]]	+	[[Category: Mowbray, S L]]
	[[Category: Chemotaxis]]		[[Category: Chemotaxis]]
	[[Category: Transport]]		[[Category: Transport]]

OCA at 19:05, 29 September 2014

2014-09-29T19:05:16Z

←Older revision		Revision as of 19:05, 29 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1urp\| PDB=1urp \| SCENE= }}~~	+	==D-RIBOSE-BINDING PROTEIN FROM ESCHERICHIA COLI==
-	===D-RIBOSE-BINDING PROTEIN FROM ESCHERICHIA COLI===	+	<StructureSection load='1urp' size='340' side='right' caption='[[1urp]], [[Resolution\|resolution]] 2.30Å' scene=''>
-	~~{{ABSTRACT_PUBMED_9641984}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1urp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1URP FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1urp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1urp RCSB], [http://www.ebi.ac.uk/pdbsum/1urp PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ur/1urp_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Conformational changes are necessary for the function of bacterial periplasmic receptors in chemotaxis and transport. Such changes allow entry and exit of ligand, and enable the correct interaction of the ligand-bound proteins with the membrane components of each system. Three open, ligand-free forms of the Escherichia coli ribose-binding protein were observed here by X-ray crystallographic studies. They are opened by 43 degrees, 50 degrees and 64 degrees with respect to the ligand-bound protein reported previously. The three open forms are not distinct, but show a clear relationship to each other. All are the product of a similar opening motion, and are stabilized by a new, almost identical packing interface between the domains. The changes are generated by similar bond rotations, although some differences in the three hinge segments are needed to accommodate the various structural scenarios. Some local repacking also occurs as interdomain contacts are lost. The least open (43 degrees) form is probably the dominant one in solution under normal conditions, although a mixture of species seems likely. The open and closed forms have distinct surfaces in the regions known to be important in chemotaxis and transport, which will differentiate their interactions with the membrane components. It seems certain that the conformational path that links the forms described here is that followed during ligand retrieval, and in ligand release into the membrane-bound permease system.

-	~~==About this Structure==~~	+	Multiple open forms of ribose-binding protein trace the path of its conformational change.,Bjorkman AJ, Mowbray SL J Mol Biol. 1998 Jun 12;279(3):651-64. PMID:9641984<ref>PMID:9641984</ref>
-	~~[[1urp]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli_k-~~12 ~~Escherichia coli k~~-~~12]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=1URP OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Molecular Playground/RBP\|Molecular Playground/RBP]]		*[[Molecular Playground/RBP\|Molecular Playground/RBP]]
	*[[Ribose-binding protein\|Ribose-binding protein]]		*[[Ribose-binding protein\|Ribose-binding protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:009641984<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
	[[Category: Bjorkman, A J.]]		[[Category: Bjorkman, A J.]]

OCA at 09:55, 11 March 2013

2013-03-11T09:55:43Z

←Older revision		Revision as of 09:55, 11 March 2013
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-	[[Image:1urp.png\|left\|200px]]
-
	{{STRUCTURE_1urp\| PDB=1urp \| SCENE= }}		{{STRUCTURE_1urp\| PDB=1urp \| SCENE= }}
-
	===D-RIBOSE-BINDING PROTEIN FROM ESCHERICHIA COLI===		===D-RIBOSE-BINDING PROTEIN FROM ESCHERICHIA COLI===
-
	{{ABSTRACT_PUBMED_9641984}}		{{ABSTRACT_PUBMED_9641984}}

OCA at 16:23, 20 October 2012

2012-10-20T16:23:32Z

←Older revision		Revision as of 16:23, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1urp]] is a 4 chain structure ~~of [[Ribose-binding protein]]~~ with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli_k12~~ Escherichia coli ~~k12~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA].	+	[[1urp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URP OCA].

	==See Also==		==See Also==
Line 16:		Line 16:
	==Reference==		==Reference==
	<ref group="xtra">PMID:009641984</ref><references group="xtra"/>		<ref group="xtra">PMID:009641984</ref><references group="xtra"/>
-	[[Category: Escherichia coli ~~k12~~]]	+	[[Category: Escherichia coli k-12]]
	[[Category: Bjorkman, A J.]]		[[Category: Bjorkman, A J.]]
	[[Category: Mowbray, S L.]]		[[Category: Mowbray, S L.]]
	[[Category: Chemotaxis]]		[[Category: Chemotaxis]]
	[[Category: Transport]]		[[Category: Transport]]