1v3j - Revision history

OCA at 07:44, 25 October 2023

2023-10-25T07:44:38Z

←Older revision		Revision as of 07:44, 25 October 2023
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	<StructureSection load='1v3j' size='340' side='right'caption='[[1v3j]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1v3j' size='340' side='right'caption='[[1v3j]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1v3j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bacs0 Bacs0~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V3J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1v3j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._1011 Bacillus sp. 1011]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V3J FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1pam\|1pam]], [[1ukq\|1ukq]], [[1v3k\|1v3k]], [[1v3l\|1v3l]], [[1v3m\|1v3m]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Cyclomaltodextrin_glucanotransferase Cyclomaltodextrin glucanotransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.19 2.4.1.19]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3j OCA], [https://pdbe.org/1v3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v3j RCSB], [https://www.ebi.ac.uk/pdbsum/1v3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v3j ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3j OCA], [https://pdbe.org/1v3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v3j RCSB], [https://www.ebi.ac.uk/pdbsum/1v3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v3j ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CDGT_BACS0 CDGT_BACS0]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacs0]]~~	+	[[Category: Bacillus sp. 1011]]
-	~~[[Category: Cyclomaltodextrin glucanotransferase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Akiba, T]]	+	[[Category: Akiba T]]
-	[[Category: Haga, K]]	+	[[Category: Haga K]]
-	[[Category: Harata, K]]	+	[[Category: Harata K]]
-	[[Category: Kanai, R]]	+	[[Category: Kanai R]]
-	[[Category: Yamane, K]]	+	[[Category: Yamane K]]
-	~~[[Category: Cgtase]]~~	+
-	~~[[Category: Cyclodextrin]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 06:24, 6 October 2021

2021-10-06T06:24:03Z

←Older revision		Revision as of 06:24, 6 October 2021
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	<StructureSection load='1v3j' size='340' side='right'caption='[[1v3j]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1v3j' size='340' side='right'caption='[[1v3j]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1v3j]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacs0 Bacs0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1V3J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1v3j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacs0 Bacs0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V3J FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pam\|1pam]], [[1ukq\|1ukq]], [[1v3k\|1v3k]], [[1v3l\|1v3l]], [[1v3m\|1v3m]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1pam\|1pam]], [[1ukq\|1ukq]], [[1v3k\|1v3k]], [[1v3l\|1v3l]], [[1v3m\|1v3m]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Cyclomaltodextrin_glucanotransferase Cyclomaltodextrin glucanotransferase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.19 2.4.1.19] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cyclomaltodextrin_glucanotransferase Cyclomaltodextrin glucanotransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.19 2.4.1.19] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1v3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3j OCA], [~~http~~://pdbe.org/1v3j PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1v3j RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1v3j PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1v3j ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3j OCA], [https://pdbe.org/1v3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v3j RCSB], [https://www.ebi.ac.uk/pdbsum/1v3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v3j ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 13:15, 1 January 2020

2020-01-01T13:15:44Z

←Older revision		Revision as of 13:15, 1 January 2020
Line 1:		Line 1:

	==Crystal structure of F283L mutant cyclodextrin glycosyltransferase==		==Crystal structure of F283L mutant cyclodextrin glycosyltransferase==
-	<StructureSection load='1v3j' size='340' side='right' caption='[[1v3j]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='1v3j' size='340' side='right'caption='[[1v3j]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1v3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacs0 Bacs0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3J FirstGlance]. <br>		<table><tr><td colspan='2'>[[1v3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacs0 Bacs0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3J FirstGlance]. <br>
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	==See Also==		==See Also==
-	*[[Glycosyltransferase\|Glycosyltransferase]]	+	*[[Glycosyltransferase 3D structures\|Glycosyltransferase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	[[Category: Bacs0]]		[[Category: Bacs0]]
	[[Category: Cyclomaltodextrin glucanotransferase]]		[[Category: Cyclomaltodextrin glucanotransferase]]
		+	[[Category: Large Structures]]
	[[Category: Akiba, T]]		[[Category: Akiba, T]]
	[[Category: Haga, K]]		[[Category: Haga, K]]

OCA at 08:05, 28 March 2018

2018-03-28T08:05:08Z

←Older revision		Revision as of 08:05, 28 March 2018
Line 1:		Line 1:
		+
	==Crystal structure of F283L mutant cyclodextrin glycosyltransferase==		==Crystal structure of F283L mutant cyclodextrin glycosyltransferase==
	<StructureSection load='1v3j' size='340' side='right' caption='[[1v3j]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1v3j' size='340' side='right' caption='[[1v3j]], [[Resolution\|resolution]] 2.00Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pam\|1pam]], [[1ukq\|1ukq]], [[1v3k\|1v3k]], [[1v3l\|1v3l]], [[1v3m\|1v3m]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pam\|1pam]], [[1ukq\|1ukq]], [[1v3k\|1v3k]], [[1v3l\|1v3l]], [[1v3m\|1v3m]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclomaltodextrin_glucanotransferase Cyclomaltodextrin glucanotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.19 2.4.1.19] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclomaltodextrin_glucanotransferase Cyclomaltodextrin glucanotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.19 2.4.1.19] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3j OCA], [http://pdbe.org/1v3j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v3j RCSB], [http://www.ebi.ac.uk/pdbsum/1v3j PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3j OCA], [http://pdbe.org/1v3j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v3j RCSB], [http://www.ebi.ac.uk/pdbsum/1v3j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1v3j ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/1v3j_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/1v3j_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 08:18, 9 February 2016

2016-02-09T08:18:47Z

←Older revision		Revision as of 08:18, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v3j ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 20:22, 10 September 2015

2015-09-10T20:22:50Z

←Older revision		Revision as of 20:22, 10 September 2015
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	<StructureSection load='1v3j' size='340' side='right' caption='[[1v3j]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1v3j' size='340' side='right' caption='[[1v3j]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1v3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_sp. Bacillus sp.~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1v3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacs0 Bacs0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3J FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pam\|1pam]], [[1ukq\|1ukq]], [[1v3k\|1v3k]], [[1v3l\|1v3l]], [[1v3m\|1v3m]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pam\|1pam]], [[1ukq\|1ukq]], [[1v3k\|1v3k]], [[1v3l\|1v3l]], [[1v3m\|1v3m]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclomaltodextrin_glucanotransferase Cyclomaltodextrin glucanotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.19 2.4.1.19] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclomaltodextrin_glucanotransferase Cyclomaltodextrin glucanotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.19 2.4.1.19] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v3j RCSB], [http://www.ebi.ac.uk/pdbsum/1v3j PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3j OCA], [http://pdbe.org/1v3j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v3j RCSB], [http://www.ebi.ac.uk/pdbsum/1v3j PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1v3j" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus sp~~]]	+	[[Category: Bacs0]]
	[[Category: Cyclomaltodextrin glucanotransferase]]		[[Category: Cyclomaltodextrin glucanotransferase]]
	[[Category: Akiba, T]]		[[Category: Akiba, T]]

OCA at 13:51, 6 January 2015

2015-01-06T13:51:38Z

←Older revision		Revision as of 13:51, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1v3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp. Bacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3J FirstGlance]. <br>		<table><tr><td colspan='2'>[[1v3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp. Bacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3J FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pam\|1pam]], [[1ukq\|1ukq]], [[1v3k\|1v3k]], [[1v3l\|1v3l]], [[1v3m\|1v3m]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pam\|1pam]], [[1ukq\|1ukq]], [[1v3k\|1v3k]], [[1v3l\|1v3l]], [[1v3m\|1v3m]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclomaltodextrin_glucanotransferase Cyclomaltodextrin glucanotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.19 2.4.1.19] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclomaltodextrin_glucanotransferase Cyclomaltodextrin glucanotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.19 2.4.1.19] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v3j RCSB], [http://www.ebi.ac.uk/pdbsum/1v3j PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v3j RCSB], [http://www.ebi.ac.uk/pdbsum/1v3j PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus sp.]]	+	[[Category: Bacillus sp]]
	[[Category: Cyclomaltodextrin glucanotransferase]]		[[Category: Cyclomaltodextrin glucanotransferase]]
-	[[Category: Akiba, T.]]	+	[[Category: Akiba, T]]
-	[[Category: Haga, K.]]	+	[[Category: Haga, K]]
-	[[Category: Harata, K.]]	+	[[Category: Harata, K]]
-	[[Category: Kanai, R.]]	+	[[Category: Kanai, R]]
-	[[Category: Yamane, K.]]	+	[[Category: Yamane, K]]
	[[Category: Cgtase]]		[[Category: Cgtase]]
	[[Category: Cyclodextrin]]		[[Category: Cyclodextrin]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 22:58, 28 September 2014

2014-09-28T22:58:37Z

←Older revision		Revision as of 22:58, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1v3j.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of F283L mutant cyclodextrin glycosyltransferase==
		+	<StructureSection load='1v3j' size='340' side='right' caption='[[1v3j]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1v3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp. Bacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3J FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pam\|1pam]], [[1ukq\|1ukq]], [[1v3k\|1v3k]], [[1v3l\|1v3l]], [[1v3m\|1v3m]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclomaltodextrin_glucanotransferase Cyclomaltodextrin glucanotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.19 2.4.1.19] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v3j RCSB], [http://www.ebi.ac.uk/pdbsum/1v3j PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/1v3j_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cyclodextrin glycosyltransferase (CGTase) belonging to the alpha-amylase family mainly catalyzes transglycosylation and produces cyclodextrins from starch and related alpha-1,4-glucans. The catalytic site of CGTase specifically conserves four aromatic residues, Phe183, Tyr195, Phe259, and Phe283, which are not found in alpha-amylase. To elucidate the structural role of Phe283, we determined the crystal structures of native and acarbose-complexed mutant CGTases in which Phe283 was replaced with leucine (F283L) or tyrosine (F283Y). The temperature factors of the region 259-269 in native F283L increased >10 A(2) compared with the wild type. The complex formation with acarbose not only increased the temperature factors (>10 A(2)) but also changed the structure of the region 257-267. This region is stabilized by interactions of Phe283 with Phe259 and Leu260 and plays an important role in the cyclodextrin binding. The conformation of the side-chains of Glu257, Phe259, His327, and Asp328 in the catalytic site was altered by the mutation of Phe283 with leucine, and this indicates that Phe283 partly arranges the structure of the catalytic site through contacts with Glu257 and Phe259. The replacement of Phe283 with tyrosine decreased the enzymatic activity in the basic pH range. The hydroxyl group of Tyr283 forms hydrogen bonds with the carboxyl group of Glu257, and the pK(a) of Glu257 in F283Y may be lower than that in the wild type.

-	~~{{STRUCTURE_1v3j\| PDB=1v3j \| SCENE= }}~~	+	Role of Phe283 in enzymatic reaction of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp.1011: Substrate binding and arrangement of the catalytic site.,Kanai R, Haga K, Akiba T, Yamane K, Harata K Protein Sci. 2004 Feb;13(2):457-65. PMID:14739329<ref>PMID:14739329</ref>

-	~~===Crystal structure~~ of ~~F283L mutant cyclodextrin glycosyltransferase===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_14739329}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1v3j]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_sp~~. ~~Bacillus sp.]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA].~~	+

	==See Also==		==See Also==
	*[[Glycosyltransferase\|Glycosyltransferase]]		*[[Glycosyltransferase\|Glycosyltransferase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:014739329<~~/~~ref~~><~~ref group="xtra">PMID:014769878</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Bacillus sp.]]		[[Category: Bacillus sp.]]
	[[Category: Cyclomaltodextrin glucanotransferase]]		[[Category: Cyclomaltodextrin glucanotransferase]]

OCA at 13:15, 20 October 2012

2012-10-20T13:15:02Z

←Older revision		Revision as of 13:15, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1v3j]] is a 2 chain structure ~~of [[Glycosyltransferase]]~~ with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp. Bacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA].	+	[[1v3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp. Bacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA].

	==See Also==		==See Also==

OCA at 11:21, 26 July 2012

2012-07-26T11:21:53Z

←Older revision		Revision as of 11:21, 26 July 2012
Line 1:		Line 1:
	[[Image:1v3j.png\|left\|200px]]		[[Image:1v3j.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1v3j", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1v3j\| PDB=1v3j \| SCENE= }}		{{STRUCTURE_1v3j\| PDB=1v3j \| SCENE= }}

	===Crystal structure of F283L mutant cyclodextrin glycosyltransferase===		===Crystal structure of F283L mutant cyclodextrin glycosyltransferase===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_14739329}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 14739329 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_14739329}}		{{ABSTRACT_PUBMED_14739329}}

	==About this Structure==		==About this Structure==
-	[[1v3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp.~~_1011~~ Bacillus sp. ~~1011~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA].	+	[[1v3j]] is a 2 chain structure of [[Glycosyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp. Bacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3J OCA].
		+
		+	==See Also==
		+	*[[Glycosyltransferase\|Glycosyltransferase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~14739329~~</ref><ref group="xtra">PMID:~~14769878~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:014739329</ref><ref group="xtra">PMID:014769878</ref><references group="xtra"/>
-	[[Category: Bacillus sp. ~~1011~~]]	+	[[Category: Bacillus sp.]]
	[[Category: Cyclomaltodextrin glucanotransferase]]		[[Category: Cyclomaltodextrin glucanotransferase]]
	[[Category: Akiba, T.]]		[[Category: Akiba, T.]]