1vbo - Revision history

OCA at 07:51, 25 October 2023

2023-10-25T07:51:35Z

←Older revision		Revision as of 07:51, 25 October 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vbo]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VBO FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vbo]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VBO FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MAN:ALPHA~~-~~D-MANNOSE'>MAN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.35Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b></td><td class="sblockDat"><div style='overflow: auto; max~~-~~height: 3em;~~'>~~[[1j4s\|1j4s]], [[1j4t\|1j4t]], [[1j4u\|1j4u]], [[1vbp\|1vbp]]~~</~~div~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [https://pdbe.org/1vbo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [https://www.ebi.ac.uk/pdbsum/1vbo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vbo ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [https://pdbe.org/1vbo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [https://www.ebi.ac.uk/pdbsum/1vbo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vbo ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q7M1T4_ARTIN Q7M1T4_ARTIN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 35:
	[[Category: Artocarpus integer]]		[[Category: Artocarpus integer]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Jeyaprakash~~, A A~~]]	+	[[Category: Jeyaprakash AA]]
-	[[Category: Srivastav, A]]	+	[[Category: Srivastav A]]
-	[[Category: Surolia, A]]	+	[[Category: Surolia A]]
-	[[Category: Vijayan, M]]	+	[[Category: Vijayan M]]
-	~~[[Category: Beta-prism]]~~	+
-	~~[[Category: Jacalin-like]]~~	+
-	~~[[Category: Lectin]]~~	+
-	~~[[Category: Mannose-specific]]~~	+
-	~~[[Category: Plant protein~~]]	+

OCA at 10:52, 6 April 2022

2022-04-06T10:52:23Z

←Older revision		Revision as of 10:52, 6 April 2022
Line 3:		Line 3:
	<StructureSection load='1vbo' size='340' side='right'caption='[[1vbo]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='1vbo' size='340' side='right'caption='[[1vbo]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1vbo]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1VBO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1vbo]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VBO FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j4s\|1j4s]], [[1j4t\|1j4t]], [[1j4u\|1j4u]], [[1vbp\|1vbp]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1j4s\|1j4s]], [[1j4t\|1j4t]], [[1j4u\|1j4u]], [[1vbp\|1vbp]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [~~http~~://pdbe.org/1vbo PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1vbo PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1vbo ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [https://pdbe.org/1vbo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [https://www.ebi.ac.uk/pdbsum/1vbo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vbo ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 06:36, 25 June 2020

2020-06-25T06:36:55Z

←Older revision		Revision as of 06:36, 25 June 2020
Line 3:		Line 3:
	<StructureSection load='1vbo' size='340' side='right'caption='[[1vbo]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='1vbo' size='340' side='right'caption='[[1vbo]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1vbo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBO OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1VBO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1vbo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1VBO FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j4s\|1j4s]], [[1j4t\|1j4t]], [[1j4u\|1j4u]], [[1vbp\|1vbp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j4s\|1j4s]], [[1j4t\|1j4t]], [[1j4u\|1j4u]], [[1vbp\|1vbp]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [http://pdbe.org/1vbo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [http://www.ebi.ac.uk/pdbsum/1vbo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vbo ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [http://pdbe.org/1vbo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [http://www.ebi.ac.uk/pdbsum/1vbo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vbo ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 10:06, 8 January 2020

2020-01-08T10:06:42Z

←Older revision		Revision as of 10:06, 8 January 2020
Line 1:		Line 1:

	==Crystal structure of artocarpin-mannotriose complex==		==Crystal structure of artocarpin-mannotriose complex==
-	<StructureSection load='1vbo' size='340' side='right' caption='[[1vbo]], [[Resolution\|resolution]] 2.35Å' scene=''>	+	<StructureSection load='1vbo' size='340' side='right'caption='[[1vbo]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vbo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VBO FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vbo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VBO FirstGlance]. <br>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Artocarpus integer]]		[[Category: Artocarpus integer]]
		+	[[Category: Large Structures]]
	[[Category: Jeyaprakash, A A]]		[[Category: Jeyaprakash, A A]]
	[[Category: Srivastav, A]]		[[Category: Srivastav, A]]

OCA at 07:13, 4 April 2018

2018-04-04T07:13:34Z

←Older revision		Revision as of 07:13, 4 April 2018
Line 1:		Line 1:
		+
	==Crystal structure of artocarpin-mannotriose complex==		==Crystal structure of artocarpin-mannotriose complex==
	<StructureSection load='1vbo' size='340' side='right' caption='[[1vbo]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='1vbo' size='340' side='right' caption='[[1vbo]], [[Resolution\|resolution]] 2.35Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j4s\|1j4s]], [[1j4t\|1j4t]], [[1j4u\|1j4u]], [[1vbp\|1vbp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j4s\|1j4s]], [[1j4t\|1j4t]], [[1j4u\|1j4u]], [[1vbp\|1vbp]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [http://pdbe.org/1vbo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [http://www.ebi.ac.uk/pdbsum/1vbo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [http://pdbe.org/1vbo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [http://www.ebi.ac.uk/pdbsum/1vbo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vbo ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/1vbo_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/1vbo_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 02:12, 9 February 2016

2016-02-09T02:12:44Z

←Older revision		Revision as of 02:12, 9 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vbo ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:36, 10 September 2015

2015-09-10T17:36:32Z

←Older revision		Revision as of 17:36, 10 September 2015
Line 6:		Line 6:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j4s\|1j4s]], [[1j4t\|1j4t]], [[1j4u\|1j4u]], [[1vbp\|1vbp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j4s\|1j4s]], [[1j4t\|1j4t]], [[1j4u\|1j4u]], [[1vbp\|1vbp]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [http://www.ebi.ac.uk/pdbsum/1vbo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [http://pdbe.org/1vbo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [http://www.ebi.ac.uk/pdbsum/1vbo PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1vbo" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:19, 6 January 2015

2015-01-06T12:19:02Z

←Older revision		Revision as of 12:19, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vbo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VBO FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vbo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VBO FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j4s\|1j4s]], [[1j4t\|1j4t]], [[1j4u\|1j4u]], [[1vbp\|1vbp]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j4s\|1j4s]], [[1j4t\|1j4t]], [[1j4u\|1j4u]], [[1vbp\|1vbp]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [http://www.ebi.ac.uk/pdbsum/1vbo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [http://www.ebi.ac.uk/pdbsum/1vbo PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Artocarpus integer]]		[[Category: Artocarpus integer]]
-	[[Category: Jeyaprakash, A A.]]	+	[[Category: Jeyaprakash, A A]]
-	[[Category: Srivastav, A.]]	+	[[Category: Srivastav, A]]
-	[[Category: Surolia, A.]]	+	[[Category: Surolia, A]]
-	[[Category: Vijayan, M.]]	+	[[Category: Vijayan, M]]
	[[Category: Beta-prism]]		[[Category: Beta-prism]]
	[[Category: Jacalin-like]]		[[Category: Jacalin-like]]

OCA at 19:23, 29 September 2014

2014-09-29T19:23:01Z

←Older revision		Revision as of 19:23, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1vbo.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of artocarpin-mannotriose complex==
		+	<StructureSection load='1vbo' size='340' side='right' caption='[[1vbo]], [[Resolution\|resolution]] 2.35Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1vbo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VBO FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j4s\|1j4s]], [[1j4t\|1j4t]], [[1j4u\|1j4u]], [[1vbp\|1vbp]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vbo RCSB], [http://www.ebi.ac.uk/pdbsum/1vbo PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/1vbo_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Artocarpin, a tetrameric lectin of molecular mass 65 kDa, is one of the two lectins extracted from the seeds of jackfruit. The structures of the complexes of artocarpin with mannotriose and mannopentose reported here, together with the structures of artocarpin and its complex with Me-alpha-mannose reported earlier, show that the lectin possesses a deep-seated binding site formed by three loops. The binding site can be considered as composed of two subsites; the primary site and the secondary site. Interactions at the primary site composed of two of the loops involve mainly hydrogen bonds, while those at the secondary site comprising the third loop are primarily van der Waals in nature. Mannotriose in its complex with the lectin interacts through all the three mannopyranosyl residues; mannopentose interacts with the protein using at least three of the five mannose residues. The complexes provide a structural explanation for the carbohydrate specificities of artocarpin. A detailed comparison with the sugar complexes of heltuba, the only other mannose-specific jacalin-like lectin with known three-dimensional structure in sugar-bound form, establishes the role of the sugar-binding loop constituting the secondary site, in conferring different specificities at the oligosaccharide level. This loop is four residues longer in artocarpin than in heltuba, providing an instance where variation in loop length is used as a strategy for generating carbohydrate specificity.

-	~~{{STRUCTURE_1vbo\| PDB=1vbo \| SCENE= }}~~	+	Structural basis for the carbohydrate specificities of artocarpin: variation in the length of a loop as a strategy for generating ligand specificity.,Jeyaprakash AA, Srivastav A, Surolia A, Vijayan M J Mol Biol. 2004 May 7;338(4):757-70. PMID:15099743<ref>PMID:15099743</ref>

-	~~===Crystal structure~~ of ~~artocarpin-mannotriose complex===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15099743}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1vbo]] is a 8 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Artocarpus_integer Artocarpus integer]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1VBO OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015099743<~~/~~ref~~><~~ref group="xtra">PMID:011902840</ref><ref group="xtra">PMID:008673603</ref><references group="xtra"~~/>	+
	[[Category: Artocarpus integer]]		[[Category: Artocarpus integer]]
	[[Category: Jeyaprakash, A A.]]		[[Category: Jeyaprakash, A A.]]

OCA at 09:29, 16 January 2013

2013-01-16T09:29:39Z

←Older revision		Revision as of 09:29, 16 January 2013
Line 1:		Line 1:
	[[Image:1vbo.png\|left\|200px]]		[[Image:1vbo.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1vbo", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1vbo\| PDB=1vbo \| SCENE= }}		{{STRUCTURE_1vbo\| PDB=1vbo \| SCENE= }}

	===Crystal structure of artocarpin-mannotriose complex===		===Crystal structure of artocarpin-mannotriose complex===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15099743}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15099743 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_15099743}}		{{ABSTRACT_PUBMED_15099743}}

Line 22:		Line 11:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15099743~~</ref><ref group="xtra">PMID:~~11902840~~</ref><ref group="xtra">PMID:~~8673603</ref><ref group="xtra">PMID:12946359~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015099743</ref><ref group="xtra">PMID:011902840</ref><ref group="xtra">PMID:008673603</ref><references group="xtra"/>
	[[Category: Artocarpus integer]]		[[Category: Artocarpus integer]]
	[[Category: Jeyaprakash, A A.]]		[[Category: Jeyaprakash, A A.]]