1vzm - Revision history

OCA at 13:28, 9 May 2024

2024-05-09T13:28:18Z

←Older revision		Revision as of 13:28, 9 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vzm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Argyrosomus_regius Argyrosomus regius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VZM FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vzm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Argyrosomus_regius Argyrosomus regius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VZM FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzm OCA], [https://pdbe.org/1vzm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vzm RCSB], [https://www.ebi.ac.uk/pdbsum/1vzm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vzm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzm OCA], [https://pdbe.org/1vzm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vzm RCSB], [https://www.ebi.ac.uk/pdbsum/1vzm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vzm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/OSTCN_ARGRE OSTCN_ARGRE]] Binds strongly to apatite and calcium (By similarity).	+	[https://www.uniprot.org/uniprot/OSTCN_ARGRE OSTCN_ARGRE] Binds strongly to apatite and calcium (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	[[Category: Argyrosomus regius]]		[[Category: Argyrosomus regius]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Alves, D]]	+	[[Category: Alves D]]
-	[[Category: Cancela~~, M L~~]]	+	[[Category: Cancela ML]]
-	[[Category: Carrondo~~, M A~~]]	+	[[Category: Carrondo MA]]
-	[[Category: Coelho, R]]	+	[[Category: Coelho R]]
-	[[Category: Frazao, C]]	+	[[Category: Frazao C]]
-	[[Category: Price~~, P A~~]]	+	[[Category: Price PA]]
-	[[Category: Simes~~, D C~~]]	+	[[Category: Simes DC]]
-	[[Category: Williamson~~, M K]]~~	+	[[Category: Williamson MK]]
-	~~[[Category: Bgp]]~~	+
-	~~[[Category: Bone]]~~	+
-	~~[[Category: Bone gla protein]]~~	+
-	~~[[Category: Calcium-binding protein]]~~	+
-	~~[[Category: Gamma carboxyl glutamic acid]]~~	+
-	~~[[Category: Hydroxyapatite]]~~	+
-	~~[[Category: Mineralization]]~~	+
-	~~[[Category: Osteocalcin]]~~	+
-	~~[[Category: Vitamin k~~]]	+

OCA at 10:29, 17 February 2021

2021-02-17T10:29:42Z

←Older revision		Revision as of 10:29, 17 February 2021
Line 3:		Line 3:
	<StructureSection load='1vzm' size='340' side='right'caption='[[1vzm]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='1vzm' size='340' side='right'caption='[[1vzm]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1vzm]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Argyrosomus_regius Argyrosomus regius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1VZM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1vzm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Argyrosomus_regius Argyrosomus regius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VZM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1vzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzm OCA], [~~http~~://pdbe.org/1vzm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1vzm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1vzm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1vzm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzm OCA], [https://pdbe.org/1vzm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vzm RCSB], [https://www.ebi.ac.uk/pdbsum/1vzm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vzm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/OSTCN_ARGRE OSTCN_ARGRE]] Binds strongly to apatite and calcium (By similarity).	+	[[https://www.uniprot.org/uniprot/OSTCN_ARGRE OSTCN_ARGRE]] Binds strongly to apatite and calcium (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 11:46, 10 May 2019

2019-05-10T11:46:06Z

←Older revision		Revision as of 11:46, 10 May 2019
Line 1:		Line 1:

	==OSTEOCALCIN FROM FISH ARGYROSOMUS REGIUS==		==OSTEOCALCIN FROM FISH ARGYROSOMUS REGIUS==
-	<StructureSection load='1vzm' size='340' side='right' caption='[[1vzm]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='1vzm' size='340' side='right'caption='[[1vzm]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vzm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Argyrosomus_regius Argyrosomus regius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VZM FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vzm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Argyrosomus_regius Argyrosomus regius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VZM FirstGlance]. <br>
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Argyrosomus regius]]		[[Category: Argyrosomus regius]]
		+	[[Category: Large Structures]]
	[[Category: Alves, D]]		[[Category: Alves, D]]
	[[Category: Cancela, M L]]		[[Category: Cancela, M L]]

OCA at 07:25, 4 April 2018

2018-04-04T07:25:54Z

←Older revision		Revision as of 07:25, 4 April 2018
Line 1:		Line 1:
		+
	==OSTEOCALCIN FROM FISH ARGYROSOMUS REGIUS==		==OSTEOCALCIN FROM FISH ARGYROSOMUS REGIUS==
	<StructureSection load='1vzm' size='340' side='right' caption='[[1vzm]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='1vzm' size='340' side='right' caption='[[1vzm]], [[Resolution\|resolution]] 1.40Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzm OCA], [http://pdbe.org/1vzm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vzm RCSB], [http://www.ebi.ac.uk/pdbsum/1vzm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzm OCA], [http://pdbe.org/1vzm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vzm RCSB], [http://www.ebi.ac.uk/pdbsum/1vzm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vzm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vz/1vzm_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vz/1vzm_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:37, 8 February 2016

2016-02-08T16:37:27Z

←Older revision		Revision as of 16:37, 8 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vzm ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 13:28, 10 September 2015

2015-09-10T13:28:26Z

←Older revision		Revision as of 13:28, 10 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vzm RCSB], [http://www.ebi.ac.uk/pdbsum/1vzm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzm OCA], [http://pdbe.org/1vzm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vzm RCSB], [http://www.ebi.ac.uk/pdbsum/1vzm PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1vzm" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 00:43, 25 December 2014

2014-12-25T00:43:10Z

←Older revision		Revision as of 00:43, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vzm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Argyrosomus_regius Argyrosomus regius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VZM FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vzm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Argyrosomus_regius Argyrosomus regius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VZM FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vzm RCSB], [http://www.ebi.ac.uk/pdbsum/1vzm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vzm RCSB], [http://www.ebi.ac.uk/pdbsum/1vzm PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/OSTCN_ARGRE OSTCN_ARGRE]] Binds strongly to apatite and calcium (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Argyrosomus regius]]		[[Category: Argyrosomus regius]]
-	[[Category: Alves, D.]]	+	[[Category: Alves, D]]
-	[[Category: Cancela, M L.]]	+	[[Category: Cancela, M L]]
-	[[Category: Carrondo, M A.]]	+	[[Category: Carrondo, M A]]
-	[[Category: Coelho, R.]]	+	[[Category: Coelho, R]]
-	[[Category: Frazao, C.]]	+	[[Category: Frazao, C]]
-	[[Category: Price, P A.]]	+	[[Category: Price, P A]]
-	[[Category: Simes, D C.]]	+	[[Category: Simes, D C]]
-	[[Category: Williamson, M K.]]	+	[[Category: Williamson, M K]]
	[[Category: Bgp]]		[[Category: Bgp]]
	[[Category: Bone]]		[[Category: Bone]]

OCA at 20:28, 29 September 2014

2014-09-29T20:28:11Z

←Older revision		Revision as of 20:28, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1vzm.~~png~~\|~~left~~\|200px]]	+	==OSTEOCALCIN FROM FISH ARGYROSOMUS REGIUS==
		+	<StructureSection load='1vzm' size='340' side='right' caption='[[1vzm]], [[Resolution\|resolution]] 1.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1vzm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Argyrosomus_regius Argyrosomus regius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VZM FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vzm RCSB], [http://www.ebi.ac.uk/pdbsum/1vzm PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vz/1vzm_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Osteocalcin is a small (45 amino acids) secreted protein found to accumulate in bone and dentin of many organisms by interacting with calcium and hydroxyapatite, through the presence of three gamma-carboxylated residues. In this work, we describe the first X-ray crystal structure for a nonmammalian osteocalcin, obtained at 1.4 A resolution, purified from the marine teleost fish Argyrosomus regius. The three-dimensional fit between the A. regius structure and that of the only other known X-ray structure, the porcine osteocalcin, revealed a superposition of the Calpha atoms of their metal chelating residues, Gla and Asp, showing that their spatial distribution is consistent with the interatomic distances of calcium cations in the hydroxyapatite crystals. In both structures, the protein forms a tight globular arrangement of their three alpha-helices while the remaining residues, at N- and C-terminal regions, have essentially no secondary structure characteristics. This study revealed the presence of a fourth gamma-carboxylation at Glu(25), not previously detected in the structure of the porcine osteocalcin or in any other of the sequentially characterized mammalian osteocalcins (human, cow, and rat). A confirmation of the fourth Gla residue in A. regius osteocalcin was achieved via LC-MS analysis. These four doubly charged residues are, together with Asp(24), concentrated in a common surface region located on the same side of the molecule. This further suggests that the known high affinity of osteocalcin for bone mineral may be derived from the clustering of calcium binding sites on this surface of the molecules.

-	~~{{STRUCTURE_1vzm\| PDB=1vzm \| SCENE= }}~~	+	Structural evidence of a fourth Gla residue in fish osteocalcin: biological implications.,Frazao C, Simes DC, Coelho R, Alves D, Williamson MK, Price PA, Cancela ML, Carrondo MA Biochemistry. 2005 Feb 1;44(4):1234-42. PMID:15667217<ref>PMID:15667217</ref>

-	~~===OSTEOCALCIN FROM FISH ARGYROSOMUS REGIUS===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15667217}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1vzm]] is~~ a ~~3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Argyrosomus_regius Argyrosomus regius]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1VZM OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015667217<~~/~~ref~~><~~ref group="xtra">PMID:012568402</ref><references group="xtra"~~/>	+
	[[Category: Argyrosomus regius]]		[[Category: Argyrosomus regius]]
	[[Category: Alves, D.]]		[[Category: Alves, D.]]

OCA at 12:32, 23 January 2013

2013-01-23T12:32:49Z

←Older revision		Revision as of 12:32, 23 January 2013
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	[[Image:1vzm.png\|left\|200px]]		[[Image:1vzm.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1vzm", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1vzm\| PDB=1vzm \| SCENE= }}		{{STRUCTURE_1vzm\| PDB=1vzm \| SCENE= }}

	===OSTEOCALCIN FROM FISH ARGYROSOMUS REGIUS===		===OSTEOCALCIN FROM FISH ARGYROSOMUS REGIUS===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15667217}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15667217 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_15667217}}		{{ABSTRACT_PUBMED_15667217}}

Line 22:		Line 11:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15667217~~</ref><ref group="xtra">PMID:~~12568402~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015667217</ref><ref group="xtra">PMID:012568402</ref><references group="xtra"/>
	[[Category: Argyrosomus regius]]		[[Category: Argyrosomus regius]]
	[[Category: Alves, D.]]		[[Category: Alves, D.]]

OCA: Protected "1vzm" [edit=sysop:move=sysop]

2011-03-14T18:27:48Z

Protected "1vzm" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:27, 14 March 2011