1wrn - Revision history

OCA at 13:48, 9 May 2024

2024-05-09T13:48:15Z

←Older revision		Revision as of 13:48, 9 May 2024
Line 3:		Line 3:
	<StructureSection load='1wrn' size='340' side='right'caption='[[1wrn]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1wrn' size='340' side='right'caption='[[1wrn]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"vibrio_subtilis"_ehrenberg_1835 "vibrio~~ subtilis~~" ehrenberg 1835~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WRN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WRN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1vea\|1vea]], [[1wmq\|1wmq]], [[1wps\|1wps]], [[1wpt\|1wpt]], [[1wpu\|1wpu]], [[1wpv\|1wpv]], [[1wro\|1wro]], [[1wrq\|1wrq]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrn OCA], [https://pdbe.org/1wrn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wrn RCSB], [https://www.ebi.ac.uk/pdbsum/1wrn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wrn ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrn OCA], [https://pdbe.org/1wrn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wrn RCSB], [https://www.ebi.ac.uk/pdbsum/1wrn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wrn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/HUTP_BACSU HUTP_BACSU]] Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.[HAMAP-Rule:MF_00779]	+	[https://www.uniprot.org/uniprot/HUTP_BACSU HUTP_BACSU] Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.[HAMAP-Rule:MF_00779]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Vibrio~~ subtilis ~~ehrenberg 1835~~]]	+	[[Category: Bacillus subtilis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kumar~~, P K.R~~]]	+	[[Category: Kumar PKR]]
-	[[Category: Kumarevel, T]]	+	[[Category: Kumarevel T]]
-	[[Category: Mizuno, H]]	+	[[Category: Mizuno H]]
-	~~[[Category: Antitermination]]~~	+
-	~~[[Category: Conformational change]]~~	+
-	~~[[Category: Hutp]]~~	+
-	~~[[Category: L-histidine]]~~	+
-	~~[[Category: Metal ion]]~~	+
-	~~[[Category: Rna binding protein~~]]	+

OCA at 16:25, 27 October 2021

2021-10-27T16:25:44Z

←Older revision		Revision as of 16:25, 27 October 2021
Line 3:		Line 3:
	<StructureSection load='1wrn' size='340' side='right'caption='[[1wrn]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1wrn' size='340' side='right'caption='[[1wrn]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1WRN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WRN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vea\|1vea]], [[1wmq\|1wmq]], [[1wps\|1wps]], [[1wpt\|1wpt]], [[1wpu\|1wpu]], [[1wpv\|1wpv]], [[1wro\|1wro]], [[1wrq\|1wrq]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1vea\|1vea]], [[1wmq\|1wmq]], [[1wps\|1wps]], [[1wpt\|1wpt]], [[1wpu\|1wpu]], [[1wpv\|1wpv]], [[1wro\|1wro]], [[1wrq\|1wrq]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1wrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrn OCA], [~~http~~://pdbe.org/1wrn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1wrn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1wrn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1wrn ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrn OCA], [https://pdbe.org/1wrn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wrn RCSB], [https://www.ebi.ac.uk/pdbsum/1wrn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wrn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/HUTP_BACSU HUTP_BACSU]] Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.[HAMAP-Rule:MF_00779]	+	[[https://www.uniprot.org/uniprot/HUTP_BACSU HUTP_BACSU]] Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.[HAMAP-Rule:MF_00779]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 17:28, 22 January 2020

2020-01-22T17:28:27Z

←Older revision		Revision as of 17:28, 22 January 2020
Line 1:		Line 1:

	==Metal Ion dependency of the antiterminator protein, HutP, for binding to the terminator region of hut mRNA- A structural basis==		==Metal Ion dependency of the antiterminator protein, HutP, for binding to the terminator region of hut mRNA- A structural basis==
-	<StructureSection load='1wrn' size='340' side='right' caption='[[1wrn]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='1wrn' size='340' side='right'caption='[[1wrn]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WRN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WRN FirstGlance]. <br>
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Vibrio subtilis ehrenberg 1835]]		[[Category: Vibrio subtilis ehrenberg 1835]]
		+	[[Category: Large Structures]]
	[[Category: Kumar, P K.R]]		[[Category: Kumar, P K.R]]
	[[Category: Kumarevel, T]]		[[Category: Kumarevel, T]]

OCA at 16:14, 11 April 2018

2018-04-11T16:14:19Z

←Older revision		Revision as of 16:14, 11 April 2018
Line 1:		Line 1:
		+
	==Metal Ion dependency of the antiterminator protein, HutP, for binding to the terminator region of hut mRNA- A structural basis==		==Metal Ion dependency of the antiterminator protein, HutP, for binding to the terminator region of hut mRNA- A structural basis==
	<StructureSection load='1wrn' size='340' side='right' caption='[[1wrn]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1wrn' size='340' side='right' caption='[[1wrn]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"~~bacillus_globigii~~"~~_migula_1900~~ "~~bacillus globigii~~" ~~migula 1900~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WRN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WRN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vea\|1vea]], [[1wmq\|1wmq]], [[1wps\|1wps]], [[1wpt\|1wpt]], [[1wpu\|1wpu]], [[1wpv\|1wpv]], [[1wro\|1wro]], [[1wrq\|1wrq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vea\|1vea]], [[1wmq\|1wmq]], [[1wps\|1wps]], [[1wpt\|1wpt]], [[1wpu\|1wpu]], [[1wpv\|1wpv]], [[1wro\|1wro]], [[1wrq\|1wrq]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrn OCA], [http://pdbe.org/1wrn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wrn RCSB], [http://www.ebi.ac.uk/pdbsum/1wrn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrn OCA], [http://pdbe.org/1wrn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wrn RCSB], [http://www.ebi.ac.uk/pdbsum/1wrn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wrn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wr/1wrn_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wr/1wrn_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wrn ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus globigii migula 1900~~]]	+	[[Category: Vibrio subtilis ehrenberg 1835]]
	[[Category: Kumar, P K.R]]		[[Category: Kumar, P K.R]]
	[[Category: Kumarevel, T]]		[[Category: Kumarevel, T]]

OCA at 17:34, 11 September 2015

2015-09-11T17:34:21Z

←Older revision		Revision as of 17:34, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1wrn' size='340' side='right' caption='[[1wrn]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1wrn' size='340' side='right' caption='[[1wrn]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_subtilis Bacillus subtilis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WRN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WRN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vea\|1vea]], [[1wmq\|1wmq]], [[1wps\|1wps]], [[1wpt\|1wpt]], [[1wpu\|1wpu]], [[1wpv\|1wpv]], [[1wro\|1wro]], [[1wrq\|1wrq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vea\|1vea]], [[1wmq\|1wmq]], [[1wps\|1wps]], [[1wpt\|1wpt]], [[1wpu\|1wpu]], [[1wpv\|1wpv]], [[1wro\|1wro]], [[1wrq\|1wrq]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wrn RCSB], [http://www.ebi.ac.uk/pdbsum/1wrn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrn OCA], [http://pdbe.org/1wrn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wrn RCSB], [http://www.ebi.ac.uk/pdbsum/1wrn PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1wrn" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus ~~subtilis~~]]	+	[[Category: Bacillus globigii migula 1900]]
	[[Category: Kumar, P K.R]]		[[Category: Kumar, P K.R]]
	[[Category: Kumarevel, T]]		[[Category: Kumarevel, T]]

OCA at 19:40, 25 December 2014

2014-12-25T19:40:21Z

←Older revision		Revision as of 19:40, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WRN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WRN FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vea\|1vea]], [[1wmq\|1wmq]], [[1wps\|1wps]], [[1wpt\|1wpt]], [[1wpu\|1wpu]], [[1wpv\|1wpv]], [[1wro\|1wro]], [[1wrq\|1wrq]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vea\|1vea]], [[1wmq\|1wmq]], [[1wps\|1wps]], [[1wpt\|1wpt]], [[1wpu\|1wpu]], [[1wpv\|1wpv]], [[1wro\|1wro]], [[1wrq\|1wrq]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wrn RCSB], [http://www.ebi.ac.uk/pdbsum/1wrn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wrn RCSB], [http://www.ebi.ac.uk/pdbsum/1wrn PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HUTP_BACSU HUTP_BACSU]] Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.[HAMAP-Rule:MF_00779]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
-	[[Category: Kumar, P K.R.]]	+	[[Category: Kumar, P K.R]]
-	[[Category: Kumarevel, T.]]	+	[[Category: Kumarevel, T]]
-	[[Category: Mizuno, H.]]	+	[[Category: Mizuno, H]]
	[[Category: Antitermination]]		[[Category: Antitermination]]
	[[Category: Conformational change]]		[[Category: Conformational change]]

OCA at 19:01, 29 September 2014

2014-09-29T19:01:31Z

←Older revision		Revision as of 19:01, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1wrn.~~png~~\|~~left~~\|200px]]	+	==Metal Ion dependency of the antiterminator protein, HutP, for binding to the terminator region of hut mRNA- A structural basis==
		+	<StructureSection load='1wrn' size='340' side='right' caption='[[1wrn]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1wrn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WRN FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vea\|1vea]], [[1wmq\|1wmq]], [[1wps\|1wps]], [[1wpt\|1wpt]], [[1wpu\|1wpu]], [[1wpv\|1wpv]], [[1wro\|1wro]], [[1wrq\|1wrq]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wrn RCSB], [http://www.ebi.ac.uk/pdbsum/1wrn PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wr/1wrn_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	HutP is an RNA-binding protein that regulates the expression of the histidine utilization (hut) operon in Bacillus subtilis, by binding to cis-acting regulatory sequences on hut mRNA. It requires L-histidine and an Mg2+ ion for binding to the specific sequence within the hut mRNA. In the present study, we show that several divalent cations can mediate the HutP-RNA interactions. The best divalent cations were Mn2+, Zn2+ and Cd2+, followed by Mg2+, Co2+ and Ni2+, while Cu2+, Yb2+ and Hg2+ were ineffective. In the HutP-RNA interactions, divalent cations cannot be replaced by monovalent cations, suggesting that a divalent metal ion is required for mediating the protein-RNA interactions. To clarify their importance, we have crystallized HutP in the presence of three different metal ions (Mg2+, Mn2+ and Ba2+), which revealed the importance of the metal ion binding site. Furthermore, these analyses clearly demonstrated how the metal ions cause the structural rearrangements that are required for the hut mRNA recognition.

-	~~{{STRUCTURE_1wrn\| PDB=1wrn \| SCENE= }}~~	+	Characterization of the metal ion binding site in the anti-terminator protein, HutP, of Bacillus subtilis.,Kumarevel T, Mizuno H, Kumar PK Nucleic Acids Res. 2005 Sep 28;33(17):5494-502. Print 2005. PMID:16192572<ref>PMID:16192572</ref>

-	~~===Metal Ion dependency~~ of the ~~antiterminator protein, HutP, for binding to the terminator region of hut mRNA- A structural basis===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16192572}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1wrn]] is a 3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_subtilis Bacillus subtilis]~~. ~~Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA].~~	+	</StructureSection>
-		+
-	~~==Reference==~~	+
-	<~~ref group="xtra"~~>~~PMID:016192572~~</~~ref~~>~~<ref group~~=~~"xtra">PMID:015758992</ref><ref group~~=~~"xtra">PMID:015242603</ref><ref group~~=~~"xtra">PMID:015273277~~</~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Kumar, P K.R.]]		[[Category: Kumar, P K.R.]]

OCA at 12:32, 23 January 2013

2013-01-23T12:32:05Z

←Older revision		Revision as of 12:32, 23 January 2013
Line 1:		Line 1:
	[[Image:1wrn.png\|left\|200px]]		[[Image:1wrn.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1wrn", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1wrn\| PDB=1wrn \| SCENE= }}		{{STRUCTURE_1wrn\| PDB=1wrn \| SCENE= }}

	===Metal Ion dependency of the antiterminator protein, HutP, for binding to the terminator region of hut mRNA- A structural basis===		===Metal Ion dependency of the antiterminator protein, HutP, for binding to the terminator region of hut mRNA- A structural basis===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16192572}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16192572 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16192572}}		{{ABSTRACT_PUBMED_16192572}}

Line 22:		Line 11:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16192572~~</ref><ref group="xtra">PMID:~~15758992~~</ref><ref group="xtra">PMID:~~15242603~~</ref><ref group="xtra">PMID:~~15273277~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016192572</ref><ref group="xtra">PMID:015758992</ref><ref group="xtra">PMID:015242603</ref><ref group="xtra">PMID:015273277</ref><references group="xtra"/>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Kumar, P K.R.]]		[[Category: Kumar, P K.R.]]

OCA: Protected "1wrn" [edit=sysop:move=sysop]

2011-03-14T20:12:04Z

Protected "1wrn" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:12, 14 March 2011

OCA at 20:12, 14 March 2011

2011-03-14T20:12:02Z

←Older revision		Revision as of 20:12, 14 March 2011
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1wrn.png\|left\|200px]]		[[Image:1wrn.png\|left\|200px]]

Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~1WRN~~ is a 3 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA].	+	[[1wrn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRN OCA].

	==Reference==		==Reference==
Line 34:		Line 33:
	[[Category: Metal ion]]		[[Category: Metal ion]]
	[[Category: Rna binding protein]]		[[Category: Rna binding protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:50:37 2009''