1xnf - Revision history

OCA at 07:56, 15 May 2024

2024-05-15T07:56:06Z

←Older revision		Revision as of 07:56, 15 May 2024
Line 3:		Line 3:
	<StructureSection load='1xnf' size='340' side='right'caption='[[1xnf]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='1xnf' size='340' side='right'caption='[[1xnf]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xnf]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1XNF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xnf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XNF FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE~~-1~~,3-DIOL'>TRS</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.98Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">nlpi ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xnf OCA], [https://pdbe.org/1xnf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xnf RCSB], [https://www.ebi.ac.uk/pdbsum/1xnf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xnf ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1xnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xnf OCA], [~~http~~://pdbe.org/1xnf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1xnf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1xnf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1xnf ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/NLPI_ECOLI NLPI_ECOLI]] May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division. Negatively controls the production of extracellular DNA (eDNA).<ref>PMID:10400590</ref> <ref>PMID:20833130</ref>	+	[https://www.uniprot.org/uniprot/NLPI_ECOLI NLPI_ECOLI] May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division. Negatively controls the production of extracellular DNA (eDNA).<ref>PMID:10400590</ref> <ref>PMID:20833130</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kajander, T]]	+	[[Category: Kajander T]]
-	[[Category: Regan, L]]	+	[[Category: Regan L]]
-	[[Category: Wilson~~, C G]]~~	+	[[Category: Wilson CG]]
-	~~[[Category: Lipoprotein]]~~	+
-	~~[[Category: Nlpi]]~~	+
-	~~[[Category: Structural genomic]]~~	+
-	~~[[Category: Tetratricopeptide]]~~	+
-	~~[[Category: Tpr]]~~	+
-	~~[[Category: Unknown function~~]]	+

OCA at 10:09, 6 January 2021

2021-01-06T10:09:58Z

←Older revision		Revision as of 10:09, 6 January 2021
Line 1:		Line 1:

	==Crystal structure of E.coli TPR-protein NlpI==		==Crystal structure of E.coli TPR-protein NlpI==
-	<StructureSection load='1xnf' size='340' side='right' caption='[[1xnf]], [[Resolution\|resolution]] 1.98Å' scene=''>	+	<StructureSection load='1xnf' size='340' side='right'caption='[[1xnf]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xnf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1XNF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xnf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1XNF FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nlpi ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nlpi ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1xnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xnf OCA], [http://pdbe.org/1xnf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xnf RCSB], [http://www.ebi.ac.uk/pdbsum/1xnf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xnf ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1xnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xnf OCA], [http://pdbe.org/1xnf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xnf RCSB], [http://www.ebi.ac.uk/pdbsum/1xnf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xnf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Kajander, T]]		[[Category: Kajander, T]]
	[[Category: Regan, L]]		[[Category: Regan, L]]

OCA at 07:23, 18 April 2018

2018-04-18T07:23:14Z

←Older revision		Revision as of 07:23, 18 April 2018
Line 1:		Line 1:
		+
	==Crystal structure of E.coli TPR-protein NlpI==		==Crystal structure of E.coli TPR-protein NlpI==
	<StructureSection load='1xnf' size='340' side='right' caption='[[1xnf]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='1xnf' size='340' side='right' caption='[[1xnf]], [[Resolution\|resolution]] 1.98Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nlpi ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nlpi ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xnf OCA], [http://pdbe.org/1xnf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xnf RCSB], [http://www.ebi.ac.uk/pdbsum/1xnf PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xnf OCA], [http://pdbe.org/1xnf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xnf RCSB], [http://www.ebi.ac.uk/pdbsum/1xnf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xnf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xn/1xnf_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xn/1xnf_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xnf ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:14, 11 September 2015

2015-09-11T23:14:01Z

←Older revision		Revision as of 23:14, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1xnf' size='340' side='right' caption='[[1xnf]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='1xnf' size='340' side='right' caption='[[1xnf]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xnf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XNF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xnf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XNF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nlpi ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nlpi ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xnf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xnf RCSB], [http://www.ebi.ac.uk/pdbsum/1xnf PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xnf OCA], [http://pdbe.org/1xnf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xnf RCSB], [http://www.ebi.ac.uk/pdbsum/1xnf PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1xnf" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Kajander, T]]		[[Category: Kajander, T]]
	[[Category: Regan, L]]		[[Category: Regan, L]]

OCA at 20:42, 25 December 2014

2014-12-25T20:42:26Z

←Older revision		Revision as of 20:42, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xnf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XNF FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xnf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XNF FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nlpi ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nlpi ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xnf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xnf RCSB], [http://www.ebi.ac.uk/pdbsum/1xnf PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xnf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xnf RCSB], [http://www.ebi.ac.uk/pdbsum/1xnf PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NLPI_ECOLI NLPI_ECOLI]] May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division. Negatively controls the production of extracellular DNA (eDNA).<ref>PMID:10400590</ref> <ref>PMID:20833130</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Kajander, T.]]	+	[[Category: Kajander, T]]
-	[[Category: Regan, L.]]	+	[[Category: Regan, L]]
-	[[Category: Wilson, C G.]]	+	[[Category: Wilson, C G]]
	[[Category: Lipoprotein]]		[[Category: Lipoprotein]]
	[[Category: Nlpi]]		[[Category: Nlpi]]

OCA at 20:04, 29 September 2014

2014-09-29T20:04:43Z

←Older revision		Revision as of 20:04, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1xnf.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of E.coli TPR-protein NlpI==
		+	<StructureSection load='1xnf' size='340' side='right' caption='[[1xnf]], [[Resolution\|resolution]] 1.98Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1xnf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XNF FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nlpi ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xnf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xnf RCSB], [http://www.ebi.ac.uk/pdbsum/1xnf PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xn/1xnf_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	There are several different families of repeat proteins. In each, a distinct structural motif is repeated in tandem to generate an elongated structure. The nonglobular, extended structures that result are particularly well suited to present a large surface area and to function as interaction domains. Many repeat proteins have been demonstrated experimentally to fold and function as independent domains. In tetratricopeptide (TPR) repeats, the repeat unit is a helix-turn-helix motif. The majority of TPR motifs occur as three to over 12 tandem repeats in different proteins. The majority of TPR structures in the Protein Data Bank are of isolated domains. Here we present the high-resolution structure of NlpI, the first structure of a complete TPR-containing protein. We show that in this instance the TPR motifs do not fold and function as an independent domain, but are fully integrated into the three-dimensional structure of a globular protein. The NlpI structure is also the first TPR structure from a prokaryote. It is of particular interest because it is a membrane-associated protein, and mutations in it alter septation and virulence.

-	~~{{STRUCTURE_1xnf\| PDB=1xnf \| SCENE= }}~~	+	The crystal structure of NlpI. A prokaryotic tetratricopeptide repeat protein with a globular fold.,Wilson CG, Kajander T, Regan L FEBS J. 2005 Jan;272(1):166-79. PMID:15634341<ref>PMID:15634341</ref>

-	~~===Crystal structure~~ of E.~~coli TPR-protein NlpI===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15634341}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1xnf]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015634341<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Kajander, T.]]		[[Category: Kajander, T.]]

OCA: Protected "1xnf" [edit=sysop:move=sysop]

2013-01-05T13:35:37Z

Protected "1xnf" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:35, 5 January 2013

OCA at 13:35, 5 January 2013

2013-01-05T13:35:34Z

←Older revision		Revision as of 13:35, 5 January 2013
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-	{{Seed}}
	[[Image:1xnf.png\|left\|200px]]		[[Image:1xnf.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1xnf", creates the "Structure Box" on the page.
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-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1xnf\| PDB=1xnf \| SCENE= }}		{{STRUCTURE_1xnf\| PDB=1xnf \| SCENE= }}

	===Crystal structure of E.coli TPR-protein NlpI===		===Crystal structure of E.coli TPR-protein NlpI===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15634341}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15634341 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_15634341}}		{{ABSTRACT_PUBMED_15634341}}

	==About this Structure==		==About this Structure==
-	~~1XNF~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA].	+	[[1xnf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15634341~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015634341</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Kajander, T.]]		[[Category: Kajander, T.]]
Line 33:		Line 21:
	[[Category: Tetratricopeptide]]		[[Category: Tetratricopeptide]]
	[[Category: Tpr]]		[[Category: Tpr]]
-		+	[[Category: Unknown function]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Wed Feb 18 06:38:01 2009''~~	+

OCA at 04:38, 18 February 2009

2009-02-18T04:38:03Z

←Older revision		Revision as of 04:38, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1XNF is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA].	+	1XNF is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNF OCA].

	==Reference==		==Reference==
-	~~The crystal structure of NlpI. A prokaryotic tetratricopeptide repeat protein with a globular fold., Wilson CG, Kajander T, Regan L, FEBS J. 2005 Jan;272(1):166-79.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/15634341 15634341]~~	+	<ref group="xtra">PMID:15634341</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Single protein]]
	[[Category: Kajander, T.]]		[[Category: Kajander, T.]]
	[[Category: Regan, L.]]		[[Category: Regan, L.]]
Line 35:		Line 34:
	[[Category: Tpr]]		[[Category: Tpr]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 29 13~~:21:~~15 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:38:01 2009''

OCA at 10:21, 29 July 2008

2008-07-29T10:21:18Z

←Older revision		Revision as of 10:21, 29 July 2008
Line 1:		Line 1:
-	[[Image:1xnf.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:1xnf.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_1xnf\| PDB=1xnf \| SCENE= }}		{{STRUCTURE_1xnf\| PDB=1xnf \| SCENE= }}

-	~~'''~~Crystal structure of E.coli TPR-protein NlpI~~'''~~	+	===Crystal structure of E.coli TPR-protein NlpI===


-	~~==Overview==~~	+	<!--
-	~~There are several different families of repeat proteins. In each, a distinct structural motif is repeated in tandem to generate an elongated structure.~~ The ~~nonglobular~~, ~~extended structures that result are particularly well suited~~ to ~~present a large surface area and to function~~ as ~~interaction domains~~. ~~Many repeat proteins have been demonstrated experimentally to fold and function as independent domains~~. ~~In tetratricopeptide (TPR~~) ~~repeats~~, ~~the repeat unit~~ is ~~a helix-turn-helix motif. The majority of TPR motifs occur as three to over 12 tandem repeats in different proteins. The majority of TPR structures in~~ the ~~Protein Data Bank are of isolated domains~~. ~~Here we present the high~~-~~resolution structure of NlpI, the first structure of a complete TPR~~-containing protein. We show that in this instance the TPR motifs do not fold and function as an independent domain, but are fully integrated into the three-dimensional structure of a globular protein. The NlpI structure is also the first TPR structure from a prokaryote. It is of particular interest because it is a membrane-associated protein, and mutations in it alter septation and virulence.	+	The line below this paragraph, {{ABSTRACT_PUBMED_15634341}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 15634341 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_15634341}}

	==About this Structure==		==About this Structure==
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	[[Category: Tetratricopeptide]]		[[Category: Tetratricopeptide]]
	[[Category: Tpr]]		[[Category: Tpr]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 15~~:15~~:45~~ 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:21:15 2008''