1xpe - Revision history

OCA at 13:36, 13 March 2024

2024-03-13T13:36:49Z

←Older revision		Revision as of 13:36, 13 March 2024
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpe OCA], [https://pdbe.org/1xpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xpe RCSB], [https://www.ebi.ac.uk/pdbsum/1xpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpe OCA], [https://pdbe.org/1xpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xpe RCSB], [https://www.ebi.ac.uk/pdbsum/1xpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpe ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	All retroviruses encapsidate their genome as a dimer of homologous single-stranded RNAs. The dimerization initiation site (DIS) of human immunodeficiency virus type 1 (HIV-1) is located in the 5'-untranslated region of the viral genome and consists of a hairpin with a 6 nt self-complementary loop sequence. Genomic RNA dimerization, a crucial step for virion infectivity, is promoted by the formation of a loop-loop complex (or kissing complex) between two DIS hairpins. Crystal structures for the subtypes A, B and F of the HIV-1 DIS kissing complex have now been solved at 2.3 A, 1.9 A and 1.6 A, respectively. They revealed a polymorphism of bulged-out residues showing clearly that their conformation is not a mere consequence of crystal packing. They also provide more insights into ion binding, hydration, and RNA conformation and flexibility. In particular, we observed the binding of spermine to the loop-loop helix, which displaced a magnesium cation important for subtype A DIS dimerization. The excellent agreement between X-ray structures and the results of chemical probing and interference data on larger viral RNA fragments shows that the crystal structures are relevant for the DIS kissing complex present in solution and in viral particles. Accordingly, these structures will be helpful for designing new drugs derived from aminoglycoside antibiotics and targeted against the RNA dimerization step of the viral life-cycle.
-
-	Polymorphism of bulged-out residues in HIV-1 RNA DIS kissing complex and structure comparison with solution studies.,Ennifar E, Dumas P J Mol Biol. 2006 Feb 24;356(3):771-82. Epub 2005 Dec 21. PMID:16403527<ref>PMID:16403527</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1xpe" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:26, 2 August 2023

2023-08-02T11:26:59Z

←Older revision		Revision as of 11:26, 2 August 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xpe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XPE FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xpe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XPE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.94Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1jjm\|1jjm]], [[1jjn\|1jjn]], [[1k9w\|1k9w]], [[1xp7\|1xp7]], [[1xpf\|1xpf]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpe OCA], [https://pdbe.org/1xpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xpe RCSB], [https://www.ebi.ac.uk/pdbsum/1xpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpe OCA], [https://pdbe.org/1xpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xpe RCSB], [https://www.ebi.ac.uk/pdbsum/1xpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpe ProSAT]</span></td></tr>
	</table>		</table>
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Dumas, P]]	+	[[Category: Dumas P]]
-	[[Category: Ennifar, E]]	+	[[Category: Ennifar E]]
-	~~[[Category: Hiv-1]]~~	+
-	~~[[Category: Loop-loop complex]]~~	+
-	~~[[Category: Rna~~]]	+

OCA at 16:41, 27 October 2021

2021-10-27T16:41:01Z

←Older revision		Revision as of 16:41, 27 October 2021
Line 3:		Line 3:
	<StructureSection load='1xpe' size='340' side='right'caption='[[1xpe]], [[Resolution\|resolution]] 1.94Å' scene=''>		<StructureSection load='1xpe' size='340' side='right'caption='[[1xpe]], [[Resolution\|resolution]] 1.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xpe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1XPE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xpe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XPE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jjm\|1jjm]], [[1jjn\|1jjn]], [[1k9w\|1k9w]], [[1xp7\|1xp7]], [[1xpf\|1xpf]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1jjm\|1jjm]], [[1jjn\|1jjn]], [[1k9w\|1k9w]], [[1xp7\|1xp7]], [[1xpf\|1xpf]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1xpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpe OCA], [~~http~~://pdbe.org/1xpe PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1xpe RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1xpe PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpe ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpe OCA], [https://pdbe.org/1xpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xpe RCSB], [https://www.ebi.ac.uk/pdbsum/1xpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpe ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:30, 22 January 2020

2020-01-22T17:30:13Z

←Older revision		Revision as of 17:30, 22 January 2020
Line 1:		Line 1:

	==HIV-1 subtype B genomic RNA Dimerization Initiation Site==		==HIV-1 subtype B genomic RNA Dimerization Initiation Site==
-	<StructureSection load='1xpe' size='340' side='right' caption='[[1xpe]], [[Resolution\|resolution]] 1.94Å' scene=''>	+	<StructureSection load='1xpe' size='340' side='right'caption='[[1xpe]], [[Resolution\|resolution]] 1.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xpe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XPE FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xpe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XPE FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Dumas, P]]		[[Category: Dumas, P]]
	[[Category: Ennifar, E]]		[[Category: Ennifar, E]]

OCA at 07:13, 18 April 2018

2018-04-18T07:13:39Z

←Older revision		Revision as of 07:13, 18 April 2018
Line 1:		Line 1:
		+
	==HIV-1 subtype B genomic RNA Dimerization Initiation Site==		==HIV-1 subtype B genomic RNA Dimerization Initiation Site==
	<StructureSection load='1xpe' size='340' side='right' caption='[[1xpe]], [[Resolution\|resolution]] 1.94Å' scene=''>		<StructureSection load='1xpe' size='340' side='right' caption='[[1xpe]], [[Resolution\|resolution]] 1.94Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jjm\|1jjm]], [[1jjn\|1jjn]], [[1k9w\|1k9w]], [[1xp7\|1xp7]], [[1xpf\|1xpf]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jjm\|1jjm]], [[1jjn\|1jjn]], [[1k9w\|1k9w]], [[1xp7\|1xp7]], [[1xpf\|1xpf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpe OCA], [http://pdbe.org/1xpe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xpe RCSB], [http://www.ebi.ac.uk/pdbsum/1xpe PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpe OCA], [http://pdbe.org/1xpe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xpe RCSB], [http://www.ebi.ac.uk/pdbsum/1xpe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpe ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:34, 12 September 2015

2015-09-12T01:34:03Z

←Older revision		Revision as of 01:34, 12 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jjm\|1jjm]], [[1jjn\|1jjn]], [[1k9w\|1k9w]], [[1xp7\|1xp7]], [[1xpf\|1xpf]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jjm\|1jjm]], [[1jjn\|1jjn]], [[1k9w\|1k9w]], [[1xp7\|1xp7]], [[1xpf\|1xpf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xpe RCSB], [http://www.ebi.ac.uk/pdbsum/1xpe PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpe OCA], [http://pdbe.org/1xpe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xpe RCSB], [http://www.ebi.ac.uk/pdbsum/1xpe PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1xpe" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:34, 15 January 2015

2015-01-15T16:34:29Z

←Older revision		Revision as of 16:34, 15 January 2015
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Dumas, P.]]	+	[[Category: Dumas, P]]
-	[[Category: Ennifar, E.]]	+	[[Category: Ennifar, E]]
	[[Category: Hiv-1]]		[[Category: Hiv-1]]
	[[Category: Loop-loop complex]]		[[Category: Loop-loop complex]]
	[[Category: Rna]]		[[Category: Rna]]

OCA at 08:32, 8 October 2014

2014-10-08T08:32:04Z

←Older revision		Revision as of 08:32, 8 October 2014
Line 1:		Line 1:
-	[[~~Image:~~1xpe.~~png~~\|~~left~~\|~~200px~~]]	+	==HIV-1 subtype B genomic RNA Dimerization Initiation Site==
		+	<StructureSection load='1xpe' size='340' side='right' caption='[[1xpe]], [[Resolution\|resolution]] 1.94Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1xpe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XPE FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jjm\|1jjm]], [[1jjn\|1jjn]], [[1k9w\|1k9w]], [[1xp7\|1xp7]], [[1xpf\|1xpf]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xpe RCSB], [http://www.ebi.ac.uk/pdbsum/1xpe PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	All retroviruses encapsidate their genome as a dimer of homologous single-stranded RNAs. The dimerization initiation site (DIS) of human immunodeficiency virus type 1 (HIV-1) is located in the 5'-untranslated region of the viral genome and consists of a hairpin with a 6 nt self-complementary loop sequence. Genomic RNA dimerization, a crucial step for virion infectivity, is promoted by the formation of a loop-loop complex (or kissing complex) between two DIS hairpins. Crystal structures for the subtypes A, B and F of the HIV-1 DIS kissing complex have now been solved at 2.3 A, 1.9 A and 1.6 A, respectively. They revealed a polymorphism of bulged-out residues showing clearly that their conformation is not a mere consequence of crystal packing. They also provide more insights into ion binding, hydration, and RNA conformation and flexibility. In particular, we observed the binding of spermine to the loop-loop helix, which displaced a magnesium cation important for subtype A DIS dimerization. The excellent agreement between X-ray structures and the results of chemical probing and interference data on larger viral RNA fragments shows that the crystal structures are relevant for the DIS kissing complex present in solution and in viral particles. Accordingly, these structures will be helpful for designing new drugs derived from aminoglycoside antibiotics and targeted against the RNA dimerization step of the viral life-cycle.

-	~~{{STRUCTURE_1xpe\| PDB=1xpe \| SCENE= }}~~	+	Polymorphism of bulged-out residues in HIV-1 RNA DIS kissing complex and structure comparison with solution studies.,Ennifar E, Dumas P J Mol Biol. 2006 Feb 24;356(3):771-82. Epub 2005 Dec 21. PMID:16403527<ref>PMID:16403527</ref>

-	~~===HIV-1 subtype B genomic RNA Dimerization Initiation Site===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16403527}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1xpe]] is~~ a ~~2 chain structure~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=1XPE OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016403527<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Dumas, P.]]		[[Category: Dumas, P.]]
	[[Category: Ennifar, E.]]		[[Category: Ennifar, E.]]

OCA: Protected "1xpe" [edit=sysop:move=sysop]

2013-01-05T12:39:34Z

Protected "1xpe" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:39, 5 January 2013

OCA at 12:39, 5 January 2013

2013-01-05T12:39:30Z

←Older revision		Revision as of 12:39, 5 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1xpe.png\|left\|200px]]		[[Image:1xpe.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1xpe", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1xpe\| PDB=1xpe \| SCENE= }}		{{STRUCTURE_1xpe\| PDB=1xpe \| SCENE= }}

	===HIV-1 subtype B genomic RNA Dimerization Initiation Site===		===HIV-1 subtype B genomic RNA Dimerization Initiation Site===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16403527}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16403527 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16403527}}		{{ABSTRACT_PUBMED_16403527}}

	==About this Structure==		==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPE OCA].	+	[[1xpe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPE OCA].

	==Reference==		==Reference==
-	~~Polymorphism of bulged-out residues in HIV-1 RNA DIS kissing complex and structure comparison with solution studies., Ennifar E, Dumas P, J Mol Biol. 2006 Feb 24;356(3):771-82. Epub 2005 Dec 21.~~ PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~16403527 16403527]~~	+	<ref group="xtra">PMID:016403527</ref><references group="xtra"/>
	[[Category: Dumas, P.]]		[[Category: Dumas, P.]]
	[[Category: Ennifar, E.]]		[[Category: Ennifar, E.]]
Line 29:		Line 17:
	[[Category: Loop-loop complex]]		[[Category: Loop-loop complex]]
	[[Category: Rna]]		[[Category: Rna]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:29:29 2008''