1yp3 - Revision history

OCA at 08:04, 15 May 2024

2024-05-15T08:04:59Z

←Older revision		Revision as of 08:04, 15 May 2024
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	<StructureSection load='1yp3' size='340' side='right'caption='[[1yp3]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='1yp3' size='340' side='right'caption='[[1yp3]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1yp3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Potato Potato~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YP3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1yp3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Solanum_tuberosum Solanum tuberosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YP3 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ATP:ADENOSINE~~-~~5-TRIPHOSPHATE'>ATP</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[1yp2\|1yp2]], [[1yp4\|1yp4]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>[https://en.wikipedia.org/wiki/Glucose-1-phosphate_adenylyltransferase Glucose-1-phosphate adenylyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.27 2.7.7.27] </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yp3 OCA], [https://pdbe.org/1yp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yp3 RCSB], [https://www.ebi.ac.uk/pdbsum/1yp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yp3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yp3 OCA], [https://pdbe.org/1yp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yp3 RCSB], [https://www.ebi.ac.uk/pdbsum/1yp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yp3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/GLGS_SOLTU GLGS_SOLTU]] This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	+	[https://www.uniprot.org/uniprot/GLGS_SOLTU GLGS_SOLTU] This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Glucose-1-phosphate adenylyltransferase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Potato~~]]	+	[[Category: Solanum tuberosum]]
-	[[Category: Ballicora~~, M A~~]]	+	[[Category: Ballicora MA]]
-	[[Category: Geiger~~, J H~~]]	+	[[Category: Geiger JH]]
-	[[Category: Jin, X]]	+	[[Category: Jin X]]
-	[[Category: Preiss, J]]	+	[[Category: Preiss J]]
-	~~[[Category: Adp-glucose pyrophosphorylase]]~~	+
-	~~[[Category: Adp-glucose synthase]]~~	+
-	~~[[Category: Agpase b]]~~	+
-	~~[[Category: Alpha-d-glucose-1-phosphate adenyl transferase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 16:31, 3 November 2021

2021-11-03T16:31:12Z

←Older revision		Revision as of 16:31, 3 November 2021
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	<StructureSection load='1yp3' size='340' side='right'caption='[[1yp3]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='1yp3' size='340' side='right'caption='[[1yp3]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1yp3]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Potato Potato]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1YP3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1yp3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Potato Potato]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YP3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yp2\|1yp2]], [[1yp4\|1yp4]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1yp2\|1yp2]], [[1yp4\|1yp4]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Glucose-1-phosphate_adenylyltransferase Glucose-1-phosphate adenylyltransferase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.27 2.7.7.27] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glucose-1-phosphate_adenylyltransferase Glucose-1-phosphate adenylyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.27 2.7.7.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1yp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yp3 OCA], [~~http~~://pdbe.org/1yp3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1yp3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1yp3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1yp3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yp3 OCA], [https://pdbe.org/1yp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yp3 RCSB], [https://www.ebi.ac.uk/pdbsum/1yp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yp3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/GLGS_SOLTU GLGS_SOLTU]] This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	+	[[https://www.uniprot.org/uniprot/GLGS_SOLTU GLGS_SOLTU]] This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 16:41, 29 January 2020

2020-01-29T16:41:19Z

←Older revision		Revision as of 16:41, 29 January 2020
Line 1:		Line 1:

	==Crystal structure of potato tuber ADP-glucose pyrophosphorylase in complex with ATP==		==Crystal structure of potato tuber ADP-glucose pyrophosphorylase in complex with ATP==
-	<StructureSection load='1yp3' size='340' side='right' caption='[[1yp3]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='1yp3' size='340' side='right'caption='[[1yp3]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1yp3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Potato Potato]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YP3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1yp3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Potato Potato]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YP3 FirstGlance]. <br>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Glucose-1-phosphate adenylyltransferase]]		[[Category: Glucose-1-phosphate adenylyltransferase]]
		+	[[Category: Large Structures]]
	[[Category: Potato]]		[[Category: Potato]]
	[[Category: Ballicora, M A]]		[[Category: Ballicora, M A]]

OCA at 06:28, 25 April 2018

2018-04-25T06:28:18Z

←Older revision		Revision as of 06:28, 25 April 2018
Line 1:		Line 1:
		+
	==Crystal structure of potato tuber ADP-glucose pyrophosphorylase in complex with ATP==		==Crystal structure of potato tuber ADP-glucose pyrophosphorylase in complex with ATP==
	<StructureSection load='1yp3' size='340' side='right' caption='[[1yp3]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='1yp3' size='340' side='right' caption='[[1yp3]], [[Resolution\|resolution]] 2.60Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yp2\|1yp2]], [[1yp4\|1yp4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yp2\|1yp2]], [[1yp4\|1yp4]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_adenylyltransferase Glucose-1-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.27 2.7.7.27] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_adenylyltransferase Glucose-1-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.27 2.7.7.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yp3 OCA], [http://pdbe.org/1yp3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yp3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yp3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yp3 OCA], [http://pdbe.org/1yp3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yp3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yp3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1yp3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yp/1yp3_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yp/1yp3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 07:15, 8 February 2016

2016-02-08T07:15:13Z

←Older revision		Revision as of 07:15, 8 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yp3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:09, 10 September 2015

2015-09-10T09:09:53Z

←Older revision		Revision as of 09:09, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1yp3' size='340' side='right' caption='[[1yp3]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='1yp3' size='340' side='right' caption='[[1yp3]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1yp3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Solanum_tuberosum Solanum tuberosum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YP3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1yp3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Potato Potato]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YP3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yp2\|1yp2]], [[1yp4\|1yp4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yp2\|1yp2]], [[1yp4\|1yp4]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_adenylyltransferase Glucose-1-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.27 2.7.7.27] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_adenylyltransferase Glucose-1-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.27 2.7.7.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yp3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yp3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yp3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yp3 OCA], [http://pdbe.org/1yp3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yp3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yp3 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1yp3" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 33:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Glucose-1-phosphate adenylyltransferase]]		[[Category: Glucose-1-phosphate adenylyltransferase]]
-	[[Category: ~~Solanum tuberosum~~]]	+	[[Category: Potato]]
	[[Category: Ballicora, M A]]		[[Category: Ballicora, M A]]
	[[Category: Geiger, J H]]		[[Category: Geiger, J H]]

OCA at 21:35, 24 December 2014

2014-12-24T21:35:13Z

←Older revision		Revision as of 21:35, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1yp3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Solanum_tuberosum Solanum tuberosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YP3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1yp3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Solanum_tuberosum Solanum tuberosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YP3 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yp2\|1yp2]], [[1yp4\|1yp4]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yp2\|1yp2]], [[1yp4\|1yp4]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_adenylyltransferase Glucose-1-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.27 2.7.7.27] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_adenylyltransferase Glucose-1-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.27 2.7.7.27] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yp3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yp3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yp3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yp3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yp3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yp3 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GLGS_SOLTU GLGS_SOLTU]] This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	[[Category: Glucose-1-phosphate adenylyltransferase]]		[[Category: Glucose-1-phosphate adenylyltransferase]]
	[[Category: Solanum tuberosum]]		[[Category: Solanum tuberosum]]
-	[[Category: Ballicora, M A.]]	+	[[Category: Ballicora, M A]]
-	[[Category: Geiger, J H.]]	+	[[Category: Geiger, J H]]
-	[[Category: Jin, X.]]	+	[[Category: Jin, X]]
-	[[Category: Preiss, J.]]	+	[[Category: Preiss, J]]
	[[Category: Adp-glucose pyrophosphorylase]]		[[Category: Adp-glucose pyrophosphorylase]]
	[[Category: Adp-glucose synthase]]		[[Category: Adp-glucose synthase]]

OCA at 21:45, 29 September 2014

2014-09-29T21:45:38Z

←Older revision		Revision as of 21:45, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1yp3.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of potato tuber ADP-glucose pyrophosphorylase in complex with ATP==
		+	<StructureSection load='1yp3' size='340' side='right' caption='[[1yp3]], [[Resolution\|resolution]] 2.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1yp3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Solanum_tuberosum Solanum tuberosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YP3 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yp2\|1yp2]], [[1yp4\|1yp4]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_adenylyltransferase Glucose-1-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.27 2.7.7.27] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yp3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yp3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yp3 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yp/1yp3_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	ADP-glucose pyrophosphorylase catalyzes the first committed and rate-limiting step in starch biosynthesis in plants and glycogen biosynthesis in bacteria. It is the enzymatic site for regulation of storage polysaccharide accumulation in plants and bacteria, being allosterically activated or inhibited by metabolites of energy flux. We report the first atomic resolution structure of ADP-glucose pyrophosphorylase. Crystals of potato tuber ADP-glucose pyrophosphorylase alpha subunit were grown in high concentrations of sulfate, resulting in the sulfate-bound, allosterically inhibited form of the enzyme. The N-terminal catalytic domain resembles a dinucleotide-binding Rossmann fold and the C-terminal domain adopts a left-handed parallel beta helix that is involved in cooperative allosteric regulation and a unique oligomerization. We also report structures of the enzyme in complex with ATP and ADP-glucose. Communication between the regulator-binding sites and the active site is both subtle and complex and involves several distinct regions of the enzyme including the N-terminus, the glucose-1-phosphate-binding site, and the ATP-binding site. These structures provide insights into the mechanism for catalysis and allosteric regulation of the enzyme.

-	~~{{STRUCTURE_1yp3\| PDB=1yp3 \| SCENE= }}~~	+	Crystal structure of potato tuber ADP-glucose pyrophosphorylase.,Jin X, Ballicora MA, Preiss J, Geiger JH EMBO J. 2005 Feb 23;24(4):694-704. Epub 2005 Feb 3. PMID:15692569<ref>PMID:15692569</ref>

-	~~===Crystal structure~~ of ~~potato tuber ADP-glucose pyrophosphorylase in complex with ATP===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15692569}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1yp3]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Solanum_tuberosum Solanum tuberosum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015692569<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Glucose-1-phosphate adenylyltransferase]]		[[Category: Glucose-1-phosphate adenylyltransferase]]
	[[Category: Solanum tuberosum]]		[[Category: Solanum tuberosum]]

OCA: Protected "1yp3" [edit=sysop:move=sysop]

2013-01-05T17:05:10Z

Protected "1yp3" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:05, 5 January 2013

OCA at 17:05, 5 January 2013

2013-01-05T17:05:08Z

←Older revision		Revision as of 17:05, 5 January 2013
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-	{{Seed}}
	[[Image:1yp3.png\|left\|200px]]		[[Image:1yp3.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1yp3", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1yp3\| PDB=1yp3 \| SCENE= }}		{{STRUCTURE_1yp3\| PDB=1yp3 \| SCENE= }}

	===Crystal structure of potato tuber ADP-glucose pyrophosphorylase in complex with ATP===		===Crystal structure of potato tuber ADP-glucose pyrophosphorylase in complex with ATP===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15692569}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15692569 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_15692569}}		{{ABSTRACT_PUBMED_15692569}}

	==About this Structure==		==About this Structure==
-	~~1YP3~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Solanum_tuberosum Solanum tuberosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA].	+	[[1yp3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Solanum_tuberosum Solanum tuberosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YP3 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15692569~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015692569</ref><references group="xtra"/>
	[[Category: Glucose-1-phosphate adenylyltransferase]]		[[Category: Glucose-1-phosphate adenylyltransferase]]
	[[Category: Solanum tuberosum]]		[[Category: Solanum tuberosum]]
Line 34:		Line 22:
	[[Category: Agpase b]]		[[Category: Agpase b]]
	[[Category: Alpha-d-glucose-1-phosphate adenyl transferase]]		[[Category: Alpha-d-glucose-1-phosphate adenyl transferase]]
-		+	[[Category: Transferase]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 20:06:37 2009''~~	+