1zr6 - Revision history

OCA at 08:12, 15 May 2024

2024-05-15T08:12:25Z

←Older revision		Revision as of 08:12, 15 May 2024
Line 3:		Line 3:
	<StructureSection load='1zr6' size='340' side='right'caption='[[1zr6]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='1zr6' size='340' side='right'caption='[[1zr6]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_34717 Atcc 34717~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sarocladium_strictum Sarocladium strictum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.55Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr6 OCA], [https://pdbe.org/1zr6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zr6 RCSB], [https://www.ebi.ac.uk/pdbsum/1zr6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr6 OCA], [https://pdbe.org/1zr6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zr6 RCSB], [https://www.ebi.ac.uk/pdbsum/1zr6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr6 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/GOOX_SARSR GOOX_SARSR] Catalyzes the selective oxidation of C1 hydroxyl moieties on mono- and disaccharides with concomitant reduction of molecular oxygen to hydrogen peroxide. This results in the formation of the corresponding lactones, which typically undergo spontaneous hydrolysis. Glucooligosaccharide oxidase is able to oxidize the monosaccharide D-glucose as well as the disaccharides maltose, cellobiose, and lactose. In addition, it shows high selectivity for cello- and maltooligosaccharides, indicating that glucooligosaccharide oxidase prefers oligosaccharides with a beta-D-glucosyl unit on the reducing end and additional sugar units linked by alpha- or beta-1,4 glucosidic bonds.<ref>PMID:16332885</ref> <ref>PMID:1764476</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 34717]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Huang, C H]]	+	[[Category: Sarocladium strictum]]
-	[[Category: Lai, W L]]	+	[[Category: Huang C-H]]
-	[[Category: Lee, M H]]	+	[[Category: Lai W-L]]
-	[[Category: Liaw, S H]]	+	[[Category: Lee M-H]]
-	[[Category: Tsai, Y C]]	+	[[Category: Liaw S-H]]
-	~~[[Category: Alpha + beta]]~~	+	[[Category: Tsai Y-C]]
-	~~[[Category: Flavoenzyme]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 08:24, 10 November 2021

2021-11-10T08:24:09Z

←Older revision		Revision as of 08:24, 10 November 2021
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	<StructureSection load='1zr6' size='340' side='right'caption='[[1zr6]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='1zr6' size='340' side='right'caption='[[1zr6]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_34717 Atcc 34717]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_34717 Atcc 34717]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1zr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr6 OCA], [~~http~~://pdbe.org/1zr6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1zr6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1zr6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr6 OCA], [https://pdbe.org/1zr6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zr6 RCSB], [https://www.ebi.ac.uk/pdbsum/1zr6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr6 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 09:40, 5 February 2020

2020-02-05T09:40:43Z

←Older revision		Revision as of 09:40, 5 February 2020
Line 1:		Line 1:

	==The crystal structure of an Acremonium strictum glucooligosaccharide oxidase reveals a novel flavinylation==		==The crystal structure of an Acremonium strictum glucooligosaccharide oxidase reveals a novel flavinylation==
-	<StructureSection load='1zr6' size='340' side='right' caption='[[1zr6]], [[Resolution\|resolution]] 1.55Å' scene=''>	+	<StructureSection load='1zr6' size='340' side='right'caption='[[1zr6]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_34717 Atcc 34717]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_34717 Atcc 34717]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 34717]]		[[Category: Atcc 34717]]
		+	[[Category: Large Structures]]
	[[Category: Huang, C H]]		[[Category: Huang, C H]]
	[[Category: Lai, W L]]		[[Category: Lai, W L]]

OCA at 09:05, 2 May 2018

2018-05-02T09:05:59Z

←Older revision		Revision as of 09:05, 2 May 2018
Line 1:		Line 1:
		+
	==The crystal structure of an Acremonium strictum glucooligosaccharide oxidase reveals a novel flavinylation==		==The crystal structure of an Acremonium strictum glucooligosaccharide oxidase reveals a novel flavinylation==
	<StructureSection load='1zr6' size='340' side='right' caption='[[1zr6]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='1zr6' size='340' side='right' caption='[[1zr6]], [[Resolution\|resolution]] 1.55Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_34717 Atcc 34717]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_34717 Atcc 34717]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr6 OCA], [http://pdbe.org/1zr6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zr6 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr6 OCA], [http://pdbe.org/1zr6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zr6 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr6 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zr/1zr6_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zr/1zr6_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zr6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:00, 11 September 2015

2015-09-11T10:00:33Z

←Older revision		Revision as of 10:00, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1zr6' size='340' side='right' caption='[[1zr6]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='1zr6' size='340' side='right' caption='[[1zr6]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sarocladium_strictum Sarocladium strictum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_34717 Atcc 34717]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zr6 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr6 OCA], [http://pdbe.org/1zr6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zr6 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr6 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1zr6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Sarocladium strictum~~]]	+	[[Category: Atcc 34717]]
	[[Category: Huang, C H]]		[[Category: Huang, C H]]
	[[Category: Lai, W L]]		[[Category: Lai, W L]]

OCA at 10:19, 8 January 2015

2015-01-08T10:19:42Z

←Older revision		Revision as of 10:19, 8 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sarocladium_strictum Sarocladium strictum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sarocladium_strictum Sarocladium strictum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zr6 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zr6 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr6 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Sarocladium strictum]]		[[Category: Sarocladium strictum]]
-	[[Category: Huang, C H.]]	+	[[Category: Huang, C H]]
-	[[Category: Lai, W L.]]	+	[[Category: Lai, W L]]
-	[[Category: Lee, M H.]]	+	[[Category: Lee, M H]]
-	[[Category: Liaw, S H.]]	+	[[Category: Liaw, S H]]
-	[[Category: Tsai, Y C.]]	+	[[Category: Tsai, Y C]]
	[[Category: Alpha + beta]]		[[Category: Alpha + beta]]
	[[Category: Flavoenzyme]]		[[Category: Flavoenzyme]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 02:42, 30 September 2014

2014-09-30T02:42:36Z

←Older revision		Revision as of 02:42, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1zr6.~~png\|left~~\|200px]]	+	==The crystal structure of an Acremonium strictum glucooligosaccharide oxidase reveals a novel flavinylation==
		+	<StructureSection load='1zr6' size='340' side='right' caption='[[1zr6]], [[Resolution\|resolution]] 1.55Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1zr6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sarocladium_strictum Sarocladium strictum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR6 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zr6 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr6 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zr/1zr6_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Glucooligosaccharide oxidase from Acremonium strictum has been screened for potential applications in oligosaccharide acid production and alternative carbohydrate detection, because it catalyzes the oxidation of glucose, maltose, lactose, cellobiose and cello- and maltooligosaccharides. We report the crystal structures of the enzyme and of its complex with an inhibitor, 5-amino-5-deoxy- cellobiono-1,5-lactam at 1.55- and 1.98-A resolution, respectively. Unexpectedly, the protein structure demonstrates the first known double attachment flavinylation, 6-S-cysteinyl, 8alpha-N1-histidyl FAD. The FAD cofactor is cross-linked to the enzyme via the C(6) atom and the 8alpha-methyl group of the isoalloxazine ring with Cys(130) and His(70), respectively. This sugar oxidase possesses an open carbohydrate-binding groove, allowing the accommodation of higher oligosaccharides. The complex structure suggests that this enzyme may prefer a beta-d-glucosyl residue at the reducing end with the conserved Tyr(429) acting as a general base to abstract the OH(1) proton in concert with the H(1) hydride transfer to the flavin N(5). Finally, a detailed comparison illustrates the structural conservation as well as the divergence between this protein and its related flavoenzymes.

-	~~{{STRUCTURE_1zr6\| PDB=1zr6 \| SCENE= }}~~	+	Crystal structure of glucooligosaccharide oxidase from Acremonium strictum: a novel flavinylation of 6-S-cysteinyl, 8alpha-N1-histidyl FAD.,Huang CH, Lai WL, Lee MH, Chen CJ, Vasella A, Tsai YC, Liaw SH J Biol Chem. 2005 Nov 18;280(46):38831-8. Epub 2005 Sep 9. PMID:16154992<ref>PMID:16154992</ref>

-	~~===The crystal structure~~ of ~~an Acremonium strictum glucooligosaccharide oxidase reveals a novel flavinylation===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16154992}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1zr6]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Sarocladium_strictum Sarocladium strictum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016154992<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Sarocladium strictum]]		[[Category: Sarocladium strictum]]
	[[Category: Huang, C H.]]		[[Category: Huang, C H.]]

OCA: Protected "1zr6" [edit=sysop:move=sysop]

2013-01-05T17:24:59Z

Protected "1zr6" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:24, 5 January 2013

OCA at 17:24, 5 January 2013

2013-01-05T17:24:56Z

←Older revision		Revision as of 17:24, 5 January 2013
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-	{{Seed}}
	[[Image:1zr6.png\|left\|200px]]		[[Image:1zr6.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1zr6", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1zr6\| PDB=1zr6 \| SCENE= }}		{{STRUCTURE_1zr6\| PDB=1zr6 \| SCENE= }}

	===The crystal structure of an Acremonium strictum glucooligosaccharide oxidase reveals a novel flavinylation===		===The crystal structure of an Acremonium strictum glucooligosaccharide oxidase reveals a novel flavinylation===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16154992}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16154992 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16154992}}		{{ABSTRACT_PUBMED_16154992}}

	==About this Structure==		==About this Structure==
-	~~1ZR6~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/~~Acremonium_strictum Acremonium~~ strictum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA].	+	[[1zr6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sarocladium_strictum Sarocladium strictum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16154992~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016154992</ref><references group="xtra"/>
-	[[Category: ~~Acremonium~~ strictum]]	+	[[Category: Sarocladium strictum]]
	[[Category: Huang, C H.]]		[[Category: Huang, C H.]]
	[[Category: Lai, W L.]]		[[Category: Lai, W L.]]
Line 33:		Line 21:
	[[Category: Flavoenzyme]]		[[Category: Flavoenzyme]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 22:57:34 2009''

OCA at 19:57, 10 June 2009

2009-06-10T19:57:34Z

←Older revision		Revision as of 19:57, 10 June 2009
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	===The crystal structure of an Acremonium strictum glucooligosaccharide oxidase reveals a novel flavinylation===		===The crystal structure of an Acremonium strictum glucooligosaccharide oxidase reveals a novel flavinylation===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_16154992}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 16154992 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_16154992}}

	==About this Structure==		==About this Structure==
	1ZR6 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Acremonium_strictum Acremonium strictum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA].		1ZR6 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Acremonium_strictum Acremonium strictum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR6 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:16154992</ref><references group="xtra"/>
	[[Category: Acremonium strictum]]		[[Category: Acremonium strictum]]
	[[Category: Huang, C H.]]		[[Category: Huang, C H.]]
Line 25:		Line 34:
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 21:26:39 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 22:57:34 2009''