2a54 - Revision history

OCA at 08:15, 15 May 2024

2024-05-15T08:15:18Z

←Older revision		Revision as of 08:15, 15 May 2024
Line 3:		Line 3:
	<StructureSection load='2a54' size='340' side='right'caption='[[2a54]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='2a54' size='340' side='right'caption='[[2a54]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2a54]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Anesu Anesu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A54 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2a54]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Anemonia_sulcata Anemonia sulcata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A54 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.45Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene~~></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2a50\|2a50]], [[2a52\|2a52]], [[2a53\|2a53]], [[2a56\|2a56]]</div></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a54 OCA], [https://pdbe.org/2a54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a54 RCSB], [https://www.ebi.ac.uk/pdbsum/2a54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a54 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a54 OCA], [https://pdbe.org/2a54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a54 RCSB], [https://www.ebi.ac.uk/pdbsum/2a54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a54 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/NFCP_ANESU NFCP_ANESU]] Pigment protein that is intensely purple in color.<ref>PMID:10852900</ref>	+	[https://www.uniprot.org/uniprot/NFCP_ANESU NFCP_ANESU] Pigment protein that is intensely purple in color.<ref>PMID:10852900</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Anesu~~]]	+	[[Category: Anemonia sulcata]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Andresen, M]]	+	[[Category: Andresen M]]
-	[[Category: Eggeling, C]]	+	[[Category: Eggeling C]]
-	[[Category: Graeter, F]]	+	[[Category: Graeter F]]
-	[[Category: Grubmueller, H]]	+	[[Category: Grubmueller H]]
-	[[Category: Hell~~, S W~~]]	+	[[Category: Hell SW]]
-	[[Category: Jakobs, S]]	+	[[Category: Jakobs S]]
-	[[Category: Schaefer, L]]	+	[[Category: Schaefer L]]
-	[[Category: Stiel~~, A C~~]]	+	[[Category: Stiel AC]]
-	[[Category: Trowitzsch, S]]	+	[[Category: Trowitzsch S]]
-	[[Category: Wahl~~, M C~~]]	+	[[Category: Wahl MC]]
-	[[Category: Weber, G]]	+	[[Category: Weber G]]
-	~~[[Category: Ascp]]~~	+
-	~~[[Category: Chromoprotein]]~~	+
-	~~[[Category: Fluorescent protein]]~~	+
-	~~[[Category: Luminescent protein]]~~	+
-	~~[[Category: Photochromic protein]]~~	+
-	~~[[Category: Reversible photoswitch~~]]	+

OCA at 06:44, 10 November 2021

2021-11-10T06:44:41Z

←Older revision		Revision as of 06:44, 10 November 2021
Line 3:		Line 3:
	<StructureSection load='2a54' size='340' side='right'caption='[[2a54]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='2a54' size='340' side='right'caption='[[2a54]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2a54]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Anesu Anesu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2A54 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2a54]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Anesu Anesu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A54 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a50\|2a50]], [[2a52\|2a52]], [[2a53\|2a53]], [[2a56\|2a56]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2a50\|2a50]], [[2a52\|2a52]], [[2a53\|2a53]], [[2a56\|2a56]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2a54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a54 OCA], [~~http~~://pdbe.org/2a54 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2a54 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2a54 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2a54 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a54 OCA], [https://pdbe.org/2a54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a54 RCSB], [https://www.ebi.ac.uk/pdbsum/2a54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a54 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/NFCP_ANESU NFCP_ANESU]] Pigment protein that is intensely purple in color.<ref>PMID:10852900</ref>	+	[[https://www.uniprot.org/uniprot/NFCP_ANESU NFCP_ANESU]] Pigment protein that is intensely purple in color.<ref>PMID:10852900</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 05:09, 13 February 2020

2020-02-13T05:09:07Z

←Older revision		Revision as of 05:09, 13 February 2020
Line 1:		Line 1:

	==fluorescent protein asFP595, A143S, on-state, 1min irradiation==		==fluorescent protein asFP595, A143S, on-state, 1min irradiation==
-	<StructureSection load='2a54' size='340' side='right' caption='[[2a54]], [[Resolution\|resolution]] 1.45Å' scene=''>	+	<StructureSection load='2a54' size='340' side='right'caption='[[2a54]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2a54]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Anesu Anesu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A54 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2a54]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Anesu Anesu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A54 FirstGlance]. <br>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Anesu]]		[[Category: Anesu]]
		+	[[Category: Large Structures]]
	[[Category: Andresen, M]]		[[Category: Andresen, M]]
	[[Category: Eggeling, C]]		[[Category: Eggeling, C]]

OCA at 06:58, 9 May 2018

2018-05-09T06:58:51Z

←Older revision		Revision as of 06:58, 9 May 2018
Line 1:		Line 1:
		+
	==fluorescent protein asFP595, A143S, on-state, 1min irradiation==		==fluorescent protein asFP595, A143S, on-state, 1min irradiation==
	<StructureSection load='2a54' size='340' side='right' caption='[[2a54]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='2a54' size='340' side='right' caption='[[2a54]], [[Resolution\|resolution]] 1.45Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a50\|2a50]], [[2a52\|2a52]], [[2a53\|2a53]], [[2a56\|2a56]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a50\|2a50]], [[2a52\|2a52]], [[2a53\|2a53]], [[2a56\|2a56]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a54 OCA], [http://pdbe.org/2a54 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2a54 RCSB], [http://www.ebi.ac.uk/pdbsum/2a54 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a54 OCA], [http://pdbe.org/2a54 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2a54 RCSB], [http://www.ebi.ac.uk/pdbsum/2a54 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2a54 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a5/2a54_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a5/2a54_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a54 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:40, 11 September 2015

2015-09-11T07:40:59Z

←Older revision		Revision as of 07:40, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2a54' size='340' side='right' caption='[[2a54]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='2a54' size='340' side='right' caption='[[2a54]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2a54]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Anemonia_sulcata Anemonia sulcata~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A54 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2a54]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Anesu Anesu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A54 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a50\|2a50]], [[2a52\|2a52]], [[2a53\|2a53]], [[2a56\|2a56]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a50\|2a50]], [[2a52\|2a52]], [[2a53\|2a53]], [[2a56\|2a56]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a54 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2a54 RCSB], [http://www.ebi.ac.uk/pdbsum/2a54 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a54 OCA], [http://pdbe.org/2a54 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2a54 RCSB], [http://www.ebi.ac.uk/pdbsum/2a54 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2a54" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Anemonia sulcata~~]]	+	[[Category: Anesu]]
	[[Category: Andresen, M]]		[[Category: Andresen, M]]
	[[Category: Eggeling, C]]		[[Category: Eggeling, C]]

OCA at 13:22, 25 December 2014

2014-12-25T13:22:40Z

←Older revision		Revision as of 13:22, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2a54]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Anemonia_sulcata Anemonia sulcata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A54 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2a54]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Anemonia_sulcata Anemonia sulcata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A54 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a50\|2a50]], [[2a52\|2a52]], [[2a53\|2a53]], [[2a56\|2a56]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a50\|2a50]], [[2a52\|2a52]], [[2a53\|2a53]], [[2a56\|2a56]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a54 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2a54 RCSB], [http://www.ebi.ac.uk/pdbsum/2a54 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a54 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2a54 RCSB], [http://www.ebi.ac.uk/pdbsum/2a54 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NFCP_ANESU NFCP_ANESU]] Pigment protein that is intensely purple in color.<ref>PMID:10852900</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Anemonia sulcata]]		[[Category: Anemonia sulcata]]
-	[[Category: Andresen, M.]]	+	[[Category: Andresen, M]]
-	[[Category: Eggeling, C.]]	+	[[Category: Eggeling, C]]
-	[[Category: Graeter, F.]]	+	[[Category: Graeter, F]]
-	[[Category: Grubmueller, H.]]	+	[[Category: Grubmueller, H]]
-	[[Category: Hell, S W.]]	+	[[Category: Hell, S W]]
-	[[Category: Jakobs, S.]]	+	[[Category: Jakobs, S]]
-	[[Category: Schaefer, L.]]	+	[[Category: Schaefer, L]]
-	[[Category: Stiel, A C.]]	+	[[Category: Stiel, A C]]
-	[[Category: Trowitzsch, S.]]	+	[[Category: Trowitzsch, S]]
-	[[Category: Wahl, M C.]]	+	[[Category: Wahl, M C]]
-	[[Category: Weber, G.]]	+	[[Category: Weber, G]]
	[[Category: Ascp]]		[[Category: Ascp]]
	[[Category: Chromoprotein]]		[[Category: Chromoprotein]]

OCA at 00:03, 30 September 2014

2014-09-30T00:03:21Z

←Older revision		Revision as of 00:03, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2a54.~~png~~\|~~left~~\|200px]]	+	==fluorescent protein asFP595, A143S, on-state, 1min irradiation==
		+	<StructureSection load='2a54' size='340' side='right' caption='[[2a54]], [[Resolution\|resolution]] 1.45Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2a54]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Anemonia_sulcata Anemonia sulcata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A54 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a50\|2a50]], [[2a52\|2a52]], [[2a53\|2a53]], [[2a56\|2a56]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a54 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2a54 RCSB], [http://www.ebi.ac.uk/pdbsum/2a54 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a5/2a54_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Proteins that can be reversibly photoswitched between a fluorescent and a nonfluorescent state bear enormous potential in diverse fields, such as data storage, in vivo protein tracking, and subdiffraction resolution light microscopy. However, these proteins could hitherto not live up to their full potential because the molecular switching mechanism is not resolved. Here, we clarify the molecular photoswitching mechanism of asFP595, a green fluorescent protein (GFP)-like protein that can be transferred from a nonfluorescent "off" to a fluorescent "on" state and back again, by green and blue light, respectively. To this end, we establish reversible photoswitching of fluorescence in whole protein crystals and show that the switching kinetics in the crystal is identical with that in solution. Subsequent x-ray analysis demonstrated that upon the absorption of a green photon, the chromophore isomerizes from a trans (off) to a cis (on) state. Molecular dynamics calculations suggest that isomerization occurs through a bottom hula twist mechanism with concomitant rotation of both bonds of the chromophoric methine ring bridge. This insight into the switching mechanism should facilitate the targeted design of photoswitchable proteins. Reversible photoswitching of the protein chromophore system within intact crystals also constitutes a step toward the use of fluorescent proteins in three-dimensional data recording.

-	~~{{STRUCTURE_2a54\| PDB=2a54 \| SCENE= }}~~	+	Structure and mechanism of the reversible photoswitch of a fluorescent protein.,Andresen M, Wahl MC, Stiel AC, Grater F, Schafer LV, Trowitzsch S, Weber G, Eggeling C, Grubmuller H, Hell SW, Jakobs S Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13070-4. Epub 2005 Aug 31. PMID:16135569<ref>PMID:16135569</ref>

-	~~===fluorescent protein asFP595~~, ~~A143S, on-state, 1min irradiation===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16135569}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2a54]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Anemonia_sulcata Anemonia sulcata]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016135569<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Anemonia sulcata]]		[[Category: Anemonia sulcata]]
	[[Category: Andresen, M.]]		[[Category: Andresen, M.]]

OCA: Protected "2a54" [edit=sysop:move=sysop]

2013-01-06T09:30:30Z

Protected "2a54" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:30, 6 January 2013

OCA at 09:30, 6 January 2013

2013-01-06T09:30:29Z

←Older revision		Revision as of 09:30, 6 January 2013
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-	{{Seed}}
	[[Image:2a54.png\|left\|200px]]		[[Image:2a54.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2a54", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2a54\| PDB=2a54 \| SCENE= }}		{{STRUCTURE_2a54\| PDB=2a54 \| SCENE= }}

	===fluorescent protein asFP595, A143S, on-state, 1min irradiation===		===fluorescent protein asFP595, A143S, on-state, 1min irradiation===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16135569}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16135569 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16135569}}		{{ABSTRACT_PUBMED_16135569}}

	==About this Structure==		==About this Structure==
-	~~2A54~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Anemonia_sulcata Anemonia sulcata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA].	+	[[2a54]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Anemonia_sulcata Anemonia sulcata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A54 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16135569~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016135569</ref><references group="xtra"/>
	[[Category: Anemonia sulcata]]		[[Category: Anemonia sulcata]]
	[[Category: Andresen, M.]]		[[Category: Andresen, M.]]
Line 42:		Line 30:
	[[Category: Photochromic protein]]		[[Category: Photochromic protein]]
	[[Category: Reversible photoswitch]]		[[Category: Reversible photoswitch]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 8 12:49:47 2009''

OCA at 09:49, 8 July 2009

2009-07-08T09:49:49Z

←Older revision		Revision as of 09:49, 8 July 2009
Line 39:		Line 39:
	[[Category: Chromoprotein]]		[[Category: Chromoprotein]]
	[[Category: Fluorescent protein]]		[[Category: Fluorescent protein]]
		+	[[Category: Luminescent protein]]
	[[Category: Photochromic protein]]		[[Category: Photochromic protein]]
	[[Category: Reversible photoswitch]]		[[Category: Reversible photoswitch]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Feb 17 17~~:17:43 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 8 12:49:47 2009''