2aa4 - Revision history

OCA at 09:12, 14 February 2024

2024-02-14T09:12:00Z

←Older revision		Revision as of 09:12, 14 February 2024
Line 3:		Line 3:
	<StructureSection load='2aa4' size='340' side='right'caption='[[2aa4]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2aa4' size='340' side='right'caption='[[2aa4]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2aa4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AA4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2aa4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AA4 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>nanK ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~562~~ "~~Bacillus coli~~" ~~Migula 1895])</td~~><~~/tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/N-acylmannosamine_kinase N-acylmannosamine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.60 2.7.1.60]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [https://pdbe.org/2aa4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [https://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aa4 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [https://pdbe.org/2aa4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [https://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aa4 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/NANK_ECOLI NANK_ECOLI]] Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P. Has also low level glucokinase activity in vitro.<ref>PMID:9864311</ref> <ref>PMID:15157072</ref> <ref>PMID:17979299</ref>	+	[https://www.uniprot.org/uniprot/NANK_ECOLI NANK_ECOLI] Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P. Has also low level glucokinase activity in vitro.<ref>PMID:9864311</ref> <ref>PMID:15157072</ref> <ref>PMID:17979299</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: N-acylmannosamine kinase]]~~	+	[[Category: Almo SC]]
-	[[Category: Almo~~, S C~~]]	+	[[Category: Burley SK]]
-	[[Category: Burley~~, S K]]~~	+	[[Category: Patskovsky Y]]
-	~~[[Category: Structural genomic~~]]	+
-	[[Category: Patskovsky, Y]]	+
-	~~[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]~~	+
-	~~[[Category: PSI, Protein structure initiative]]~~	+
-	~~[[Category: Sugar methabolism]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 08:28, 27 January 2021

2021-01-27T08:28:26Z

←Older revision		Revision as of 08:28, 27 January 2021
Line 1:		Line 1:

	==Crystal structure of Escherichia coli putative N-ACETYLMANNOSAMINE KINASE, New York Structural Genomics Consortium==		==Crystal structure of Escherichia coli putative N-ACETYLMANNOSAMINE KINASE, New York Structural Genomics Consortium==
-	<StructureSection load='2aa4' size='340' side='right' caption='[[2aa4]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='2aa4' size='340' side='right'caption='[[2aa4]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2aa4]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2AA4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2aa4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AA4 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nanK ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nanK ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/N-acylmannosamine_kinase N-acylmannosamine kinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.60 2.7.1.60] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/N-acylmannosamine_kinase N-acylmannosamine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.60 2.7.1.60] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [~~http~~://pdbe.org/2aa4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2aa4 ProSAT], [~~http~~://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [https://pdbe.org/2aa4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [https://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aa4 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/NANK_ECOLI NANK_ECOLI]] Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P. Has also low level glucokinase activity in vitro.<ref>PMID:9864311</ref> <ref>PMID:15157072</ref> <ref>PMID:17979299</ref>	+	[[https://www.uniprot.org/uniprot/NANK_ECOLI NANK_ECOLI]] Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P. Has also low level glucokinase activity in vitro.<ref>PMID:9864311</ref> <ref>PMID:15157072</ref> <ref>PMID:17979299</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: N-acylmannosamine kinase]]		[[Category: N-acylmannosamine kinase]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]

OCA at 07:20, 9 May 2018

2018-05-09T07:20:06Z

←Older revision		Revision as of 07:20, 9 May 2018
Line 1:		Line 1:
		+
	==Crystal structure of Escherichia coli putative N-ACETYLMANNOSAMINE KINASE, New York Structural Genomics Consortium==		==Crystal structure of Escherichia coli putative N-ACETYLMANNOSAMINE KINASE, New York Structural Genomics Consortium==
	<StructureSection load='2aa4' size='340' side='right' caption='[[2aa4]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2aa4' size='340' side='right' caption='[[2aa4]], [[Resolution\|resolution]] 2.20Å' scene=''>
Line 6:		Line 7:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nanK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nanK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acylmannosamine_kinase N-acylmannosamine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.60 2.7.1.60] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acylmannosamine_kinase N-acylmannosamine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.60 2.7.1.60] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [http://pdbe.org/2aa4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [http://pdbe.org/2aa4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2aa4 ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aa/2aa4_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aa/2aa4_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aa4 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	== References ==		== References ==

OCA at 01:50, 12 September 2015

2015-09-12T01:50:04Z

←Older revision		Revision as of 01:50, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='2aa4' size='340' side='right' caption='[[2aa4]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2aa4' size='340' side='right' caption='[[2aa4]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2aa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AA4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2aa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AA4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nanK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nanK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acylmannosamine_kinase N-acylmannosamine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.60 2.7.1.60] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acylmannosamine_kinase N-acylmannosamine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.60 2.7.1.60] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [http://pdbe.org/2aa4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 24:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: N-acylmannosamine kinase]]		[[Category: N-acylmannosamine kinase]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]

OCA at 22:15, 25 December 2014

2014-12-25T22:15:32Z

←Older revision		Revision as of 22:15, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NANK_ECOLI NANK_ECOLI]] Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P. Has also low level glucokinase activity in vitro.<ref>PMID:9864311</ref> <ref>PMID:15157072</ref> <ref>PMID:17979299</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 12:58, 6 November 2014

2014-11-06T12:58:40Z

←Older revision		Revision as of 12:58, 6 November 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2aa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AA4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2aa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AA4 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nanK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nanK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acylmannosamine_kinase N-acylmannosamine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.60 2.7.1.60] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acylmannosamine_kinase N-acylmannosamine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.60 2.7.1.60] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 22:		Line 22:
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: N-acylmannosamine kinase]]		[[Category: N-acylmannosamine kinase]]
-	[[Category: Almo, S C.]]	+	[[Category: Almo, S C]]
-	[[Category: Burley, S K~~.]]~~	+	[[Category: Burley, S K]]
-	~~[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]~~	+
-	~~[[Category: Patskovsky, Y.]]~~	+
-	~~[[Category: New york sgx research center for structural genomic]]~~	+
-	~~[[Category: Nysgxrc]]~~	+
-	~~[[Category: Protein structure initiative]]~~	+
-	~~[[Category: Psi~~]]	+
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
		+	[[Category: Patskovsky, Y]]
		+	[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
		+	[[Category: PSI, Protein structure initiative]]
	[[Category: Sugar methabolism]]		[[Category: Sugar methabolism]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 02:07, 30 September 2014

2014-09-30T02:07:41Z

←Older revision		Revision as of 02:07, 30 September 2014
Line 1:		Line 1:
-	~~[[Image:2aa4.png\|left\|200px]]~~	+	==Crystal structure of Escherichia coli putative N-ACETYLMANNOSAMINE KINASE, New York Structural Genomics Consortium==
-		+	<StructureSection load='2aa4' size='340' side='right' caption='[[2aa4]], [[Resolution\|resolution]] 2.20Å' scene=''>
-	~~{{STRUCTURE_2aa4\| PDB=2aa4 \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2aa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AA4 FirstGlance]. <br>
-	===Crystal structure of Escherichia coli putative N-ACETYLMANNOSAMINE KINASE, New York Structural Genomics Consortium===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nanK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acylmannosamine_kinase N-acylmannosamine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.60 2.7.1.60] </span></td></tr>
-	==~~About this Structure~~==	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aa4 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa4 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2aa4 TOPSAN]</span></td></tr>
-	[[2aa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA].	+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aa/2aa4_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: N-acylmannosamine kinase]]		[[Category: N-acylmannosamine kinase]]

OCA: Protected "2aa4" [edit=sysop:move=sysop]

2013-01-06T11:20:32Z

Protected "2aa4" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:20, 6 January 2013

OCA at 11:20, 6 January 2013

2013-01-06T11:20:30Z

←Older revision		Revision as of 11:20, 6 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2aa4.png\|left\|200px]]		[[Image:2aa4.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2aa4", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2aa4\| PDB=2aa4 \| SCENE= }}		{{STRUCTURE_2aa4\| PDB=2aa4 \| SCENE= }}

Line 14:		Line 7:

	==About this Structure==		==About this Structure==
-	~~2AA4~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA].	+	[[2aa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA].
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: N-acylmannosamine kinase]]		[[Category: N-acylmannosamine kinase]]
	[[Category: Almo, S C.]]		[[Category: Almo, S C.]]
	[[Category: Burley, S K.]]		[[Category: Burley, S K.]]
-	[[Category: NYSGXRC, New York ~~Structural GenomiX~~ Research ~~Consortium~~.]]	+	[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
	[[Category: Patskovsky, Y.]]		[[Category: Patskovsky, Y.]]
-	[[Category: New york ~~structural genomix~~ research ~~consortium~~]]	+	[[Category: New york sgx research center for structural genomic]]
	[[Category: Nysgxrc]]		[[Category: Nysgxrc]]
	[[Category: Protein structure initiative]]		[[Category: Protein structure initiative]]
Line 27:		Line 20:
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Sugar methabolism]]		[[Category: Sugar methabolism]]
-		+	[[Category: Transferase]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Sun Nov 16 17:43:53 2008''~~	+

OCA at 15:43, 16 November 2008

2008-11-16T15:43:54Z

←Older revision		Revision as of 15:43, 16 November 2008
Line 14:		Line 14:

	==About this Structure==		==About this Structure==
-	2AA4 is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA].	+	2AA4 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA4 OCA].
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: N-acylmannosamine kinase]]		[[Category: N-acylmannosamine kinase]]
-	[[Category: Single protein]]
	[[Category: Almo, S C.]]		[[Category: Almo, S C.]]
	[[Category: Burley, S K.]]		[[Category: Burley, S K.]]
Line 29:		Line 28:
	[[Category: Sugar methabolism]]		[[Category: Sugar methabolism]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Sep 29 05~~:41:58 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 17:43:53 2008''