2asb - Revision history

OCA at 07:29, 23 August 2023

2023-08-23T07:29:11Z

←Older revision		Revision as of 07:29, 23 August 2023
Line 3:		Line 3:
	<StructureSection load='2asb' size='340' side='right'caption='[[2asb]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2asb' size='340' side='right'caption='[[2asb]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2asb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus~~ tuberculosis~~" (zopf 1883) klein 1884~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ASB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2asb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ASB FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[2atw\|2atw]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">nusA ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=~~5&~~id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2asb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asb OCA], [https://pdbe.org/2asb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2asb RCSB], [https://www.ebi.ac.uk/pdbsum/2asb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2asb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2asb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asb OCA], [https://pdbe.org/2asb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2asb RCSB], [https://www.ebi.ac.uk/pdbsum/2asb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2asb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/NUSA_MYCTU NUSA_MYCTU]] Participates in both transcription termination and antitermination (By similarity).[HAMAP-Rule:MF_00945]	+	[https://www.uniprot.org/uniprot/NUSA_MYCTU NUSA_MYCTU] Participates in both transcription termination and antitermination (By similarity).[HAMAP-Rule:MF_00945]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arnvig~~, K B~~]]	+	[[Category: Mycobacterium tuberculosis]]
-	[[Category: Beuth, B]]	+	[[Category: Arnvig KB]]
-	[[Category: Martin~~, S R~~]]	+	[[Category: Beuth B]]
-	[[Category: Pennell, S]]	+	[[Category: Martin SR]]
-	[[Category: Taylor~~, I A]]~~	+	[[Category: Pennell S]]
-	~~[[Category: Protein-rna complex]]~~	+	[[Category: Taylor IA]]
-	~~[[Category: Transcription-rna complex~~]]	+

OCA at 08:37, 27 January 2021

2021-01-27T08:37:28Z

←Older revision		Revision as of 08:37, 27 January 2021
Line 1:		Line 1:

	==Structure of a Mycobacterium tuberculosis NusA-RNA complex==		==Structure of a Mycobacterium tuberculosis NusA-RNA complex==
-	<StructureSection load='2asb' size='340' side='right' caption='[[2asb]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='2asb' size='340' side='right'caption='[[2asb]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2asb]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ASB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2asb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ASB FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2atw\|2atw]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2atw\|2atw]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nusA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nusA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2asb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asb OCA], [~~http~~://pdbe.org/2asb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2asb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2asb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2asb ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2asb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asb OCA], [https://pdbe.org/2asb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2asb RCSB], [https://www.ebi.ac.uk/pdbsum/2asb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2asb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/NUSA_MYCTU NUSA_MYCTU]] Participates in both transcription termination and antitermination (By similarity).[HAMAP-Rule:MF_00945]	+	[[https://www.uniprot.org/uniprot/NUSA_MYCTU NUSA_MYCTU]] Participates in both transcription termination and antitermination (By similarity).[HAMAP-Rule:MF_00945]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Arnvig, K B]]		[[Category: Arnvig, K B]]
	[[Category: Beuth, B]]		[[Category: Beuth, B]]

OCA at 06:51, 9 May 2018

2018-05-09T06:51:10Z

←Older revision		Revision as of 06:51, 9 May 2018
Line 1:		Line 1:
		+
	==Structure of a Mycobacterium tuberculosis NusA-RNA complex==		==Structure of a Mycobacterium tuberculosis NusA-RNA complex==
	<StructureSection load='2asb' size='340' side='right' caption='[[2asb]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2asb' size='340' side='right' caption='[[2asb]], [[Resolution\|resolution]] 1.50Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2atw\|2atw]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2atw\|2atw]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nusA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nusA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2asb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asb OCA], [http://pdbe.org/2asb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2asb RCSB], [http://www.ebi.ac.uk/pdbsum/2asb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2asb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asb OCA], [http://pdbe.org/2asb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2asb RCSB], [http://www.ebi.ac.uk/pdbsum/2asb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2asb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/as/2asb_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/as/2asb_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2asb ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:45, 11 September 2015

2015-09-11T12:45:54Z

←Older revision		Revision as of 12:45, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2asb' size='340' side='right' caption='[[2asb]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2asb' size='340' side='right' caption='[[2asb]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2asb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mycobacterium_tuberculosis Mycobacterium~~ tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ASB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2asb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ASB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2atw\|2atw]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2atw\|2atw]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nusA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 ~~Mycobacterium~~ tuberculosis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nusA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2asb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2asb RCSB], [http://www.ebi.ac.uk/pdbsum/2asb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2asb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asb OCA], [http://pdbe.org/2asb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2asb RCSB], [http://www.ebi.ac.uk/pdbsum/2asb PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2asb" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Mycobacterium tuberculosis]]
	[[Category: Arnvig, K B]]		[[Category: Arnvig, K B]]
	[[Category: Beuth, B]]		[[Category: Beuth, B]]

OCA at 16:38, 25 December 2014

2014-12-25T16:38:36Z

←Older revision		Revision as of 16:38, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2asb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ASB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2asb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ASB FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2atw\|2atw]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2atw\|2atw]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nusA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nusA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2asb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2asb RCSB], [http://www.ebi.ac.uk/pdbsum/2asb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2asb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2asb RCSB], [http://www.ebi.ac.uk/pdbsum/2asb PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NUSA_MYCTU NUSA_MYCTU]] Participates in both transcription termination and antitermination (By similarity).[HAMAP-Rule:MF_00945]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
-	[[Category: Arnvig, K B.]]	+	[[Category: Arnvig, K B]]
-	[[Category: Beuth, B.]]	+	[[Category: Beuth, B]]
-	[[Category: Martin, S R.]]	+	[[Category: Martin, S R]]
-	[[Category: Pennell, S.]]	+	[[Category: Pennell, S]]
-	[[Category: Taylor, I A.]]	+	[[Category: Taylor, I A]]
	[[Category: Protein-rna complex]]		[[Category: Protein-rna complex]]
	[[Category: Transcription-rna complex]]		[[Category: Transcription-rna complex]]

OCA at 02:26, 30 September 2014

2014-09-30T02:26:29Z

←Older revision		Revision as of 02:26, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2asb.~~png~~\|~~left~~\|200px]]	+	==Structure of a Mycobacterium tuberculosis NusA-RNA complex==
		+	<StructureSection load='2asb' size='340' side='right' caption='[[2asb]], [[Resolution\|resolution]] 1.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2asb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ASB FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2atw\|2atw]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nusA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2asb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2asb RCSB], [http://www.ebi.ac.uk/pdbsum/2asb PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/as/2asb_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	NusA is a key regulator of bacterial transcriptional elongation, pausing, termination and antitermination, yet relatively little is known about the molecular basis of its activity in these fundamental processes. In Mycobacterium tuberculosis, NusA has been shown to bind with high affinity and specificity to BoxB-BoxA-BoxC antitermination sequences within the leader region of the single ribosomal RNA (rRNA) operon. We have determined high-resolution X-ray structures of a complex of NusA with two short oligo-ribonucleotides derived from the BoxC stem-loop motif and have characterised the interaction of NusA with a variety of RNAs derived from the antitermination region. These structures reveal the RNA bound in an extended conformation to a large interacting surface on both KH domains. Combining structural data with observed spectral and calorimetric changes, we now show that NusA binding destabilises secondary structure within rRNA antitermination sequences and propose a model where NusA functions as a chaperone for nascently forming RNA structures.

-	~~{{STRUCTURE_2asb\| PDB=2asb \| SCENE= }}~~	+	Structure of a Mycobacterium tuberculosis NusA-RNA complex.,Beuth B, Pennell S, Arnvig KB, Martin SR, Taylor IA EMBO J. 2005 Oct 19;24(20):3576-87. Epub 2005 Sep 29. PMID:16193062<ref>PMID:16193062</ref>

-	~~===Structure~~ of ~~a Mycobacterium tuberculosis NusA-RNA complex===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16193062}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2asb]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016193062<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
	[[Category: Arnvig, K B.]]		[[Category: Arnvig, K B.]]

OCA: Protected "2asb" [edit=sysop:move=sysop]

2013-01-06T11:38:54Z

Protected "2asb" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:38, 6 January 2013

OCA at 11:38, 6 January 2013

2013-01-06T11:38:51Z

←Older revision		Revision as of 11:38, 6 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2asb.png\|left\|200px]]		[[Image:2asb.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2asb", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2asb\| PDB=2asb \| SCENE= }}		{{STRUCTURE_2asb\| PDB=2asb \| SCENE= }}

	===Structure of a Mycobacterium tuberculosis NusA-RNA complex===		===Structure of a Mycobacterium tuberculosis NusA-RNA complex===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16193062}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16193062 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16193062}}		{{ABSTRACT_PUBMED_16193062}}

	==About this Structure==		==About this Structure==
-	~~2ASB~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA].	+	[[2asb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16193062~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016193062</ref><references group="xtra"/>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
	[[Category: Arnvig, K B.]]		[[Category: Arnvig, K B.]]
Line 31:		Line 19:
	[[Category: Taylor, I A.]]		[[Category: Taylor, I A.]]
	[[Category: Protein-rna complex]]		[[Category: Protein-rna complex]]
-		+	[[Category: Transcription-rna complex]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 21:58:23 2009''~~	+

OCA at 19:58, 17 February 2009

2009-02-17T19:58:23Z

←Older revision		Revision as of 19:58, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2ASB is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA].	+	2ASB is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASB OCA].

	==Reference==		==Reference==
-	~~Structure of a Mycobacterium tuberculosis NusA-RNA complex., Beuth B, Pennell S, Arnvig KB, Martin SR, Taylor IA, EMBO J. 2005 Oct 19;24(20):3576-87. Epub 2005 Sep 29.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16193062 16193062]~~	+	<ref group="xtra">PMID:16193062</ref><references group="xtra"/>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
-	[[Category: Single protein]]
	[[Category: Arnvig, K B.]]		[[Category: Arnvig, K B.]]
	[[Category: Beuth, B.]]		[[Category: Beuth, B.]]
Line 33:		Line 32:
	[[Category: Protein-rna complex]]		[[Category: Protein-rna complex]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 29 06~~:11:~~41 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:58:23 2009''

OCA at 03:11, 29 July 2008

2008-07-29T03:11:46Z

←Older revision		Revision as of 03:11, 29 July 2008
Line 1:		Line 1:
-	[[Image:2asb.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2asb.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2asb\| PDB=2asb \| SCENE= }}		{{STRUCTURE_2asb\| PDB=2asb \| SCENE= }}

-	~~'''~~Structure of a Mycobacterium tuberculosis NusA-RNA complex~~'''~~	+	===Structure of a Mycobacterium tuberculosis NusA-RNA complex===


-	~~==Overview==~~	+	<!--
-	~~NusA is a key regulator of bacterial transcriptional elongation~~, ~~pausing~~, ~~termination and antitermination, yet relatively little is known about~~ the ~~molecular basis of its activity in these fundamental processes. In Mycobacterium tuberculosis, NusA has been shown~~ to ~~bind with high affinity and specificity to BoxB-BoxA-BoxC antitermination sequences within~~ the ~~leader region of the single ribosomal RNA~~ (~~rRNA) operon~~. We have determined high-resolution X-ray structures of a complex of NusA with two short oligo-ribonucleotides derived from the BoxC stem-loop motif and have characterised the interaction of NusA with a variety of RNAs derived from the antitermination region. ~~These structures reveal the RNA bound in an extended conformation to a large interacting surface on both KH domains. Combining structural data with observed spectral and calorimetric changes~~, ~~we now show that NusA binding destabilises secondary structure within rRNA antitermination sequences and propose a model~~ where ~~NusA functions as a chaperone for nascently forming RNA structures~~.	+	The line below this paragraph, {{ABSTRACT_PUBMED_16193062}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 16193062 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_16193062}}

	==About this Structure==		==About this Structure==
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	[[Category: Taylor, I A.]]		[[Category: Taylor, I A.]]
	[[Category: Protein-rna complex]]		[[Category: Protein-rna complex]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 19~~:25:00 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:11:41 2008''