2b24 - Revision history

OCA at 07:32, 23 August 2023

2023-08-23T07:32:50Z

←Older revision		Revision as of 07:32, 23 August 2023
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	<StructureSection load='2b24' size='340' side='right'caption='[[2b24]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='2b24' size='340' side='right'caption='[[2b24]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2b24]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B24 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2b24]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_sp._NCIMB_12038 Rhodococcus sp. NCIMB 12038]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B24 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>~~, ~~<scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IND:INDOLE'>IND</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2b1x\|2b1x]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IND:INDOLE'>IND</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:</b></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b24 OCA], [https://pdbe.org/2b24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b24 RCSB], [https://www.ebi.ac.uk/pdbsum/2b24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b24 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b24 OCA], [https://pdbe.org/2b24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b24 RCSB], [https://www.ebi.ac.uk/pdbsum/2b24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b24 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9X3R9_9NOCA Q9X3R9_9NOCA]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Naphthalene 1,2-dioxygenase]]~~	+	[[Category: Rhodococcus sp. NCIMB 12038]]
-	[[Category: Rhodococcus sp]]	+	[[Category: Allen CC]]
-	[[Category: Allen~~, C C~~]]	+	[[Category: Gakhar L]]
-	[[Category: Gakhar, L]]	+	[[Category: Larkin MJ]]
-	[[Category: Larkin~~, M J~~]]	+	[[Category: Lipscomb DA]]
-	[[Category: Lipscomb~~, D A~~]]	+	[[Category: Malik ZA]]
-	[[Category: Malik~~, Z A~~]]	+	[[Category: Ramaswamy S]]
-	[[Category: Ramaswamy, S]]	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Rieske non-heme iron oxygenase~~]]	+

OCA at 13:04, 24 November 2021

2021-11-24T13:04:51Z

←Older revision		Revision as of 13:04, 24 November 2021
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	<StructureSection load='2b24' size='340' side='right'caption='[[2b24]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='2b24' size='340' side='right'caption='[[2b24]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2b24]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B24 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2B24 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2b24]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B24 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IND:INDOLE'>IND</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IND:INDOLE'>IND</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b1x\|2b1x]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2b1x\|2b1x]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b24 OCA], [~~http~~://pdbe.org/2b24 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2b24 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2b24 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2b24 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b24 OCA], [https://pdbe.org/2b24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b24 RCSB], [https://www.ebi.ac.uk/pdbsum/2b24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b24 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:59, 19 February 2020

2020-02-19T07:59:16Z

←Older revision		Revision as of 07:59, 19 February 2020
Line 1:		Line 1:

	==Crystal structure of naphthalene 1,2-dioxygenase from Rhodococcus sp. bound to indole==		==Crystal structure of naphthalene 1,2-dioxygenase from Rhodococcus sp. bound to indole==
-	<StructureSection load='2b24' size='340' side='right' caption='[[2b24]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='2b24' size='340' side='right'caption='[[2b24]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2b24]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B24 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2b24]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B24 FirstGlance]. <br>
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Dioxygenase\|Dioxygenase]]	+	*[[Dioxygenase 3D structures\|Dioxygenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Naphthalene 1,2-dioxygenase]]		[[Category: Naphthalene 1,2-dioxygenase]]
	[[Category: Rhodococcus sp]]		[[Category: Rhodococcus sp]]

OCA at 06:20, 16 May 2018

2018-05-16T06:20:01Z

←Older revision		Revision as of 06:20, 16 May 2018
Line 1:		Line 1:
		+
	==Crystal structure of naphthalene 1,2-dioxygenase from Rhodococcus sp. bound to indole==		==Crystal structure of naphthalene 1,2-dioxygenase from Rhodococcus sp. bound to indole==
	<StructureSection load='2b24' size='340' side='right' caption='[[2b24]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='2b24' size='340' side='right' caption='[[2b24]], [[Resolution\|resolution]] 3.00Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b1x\|2b1x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b1x\|2b1x]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b24 OCA], [http://pdbe.org/2b24 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b24 RCSB], [http://www.ebi.ac.uk/pdbsum/2b24 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b24 OCA], [http://pdbe.org/2b24 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b24 RCSB], [http://www.ebi.ac.uk/pdbsum/2b24 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2b24 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/2b24_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/2b24_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:19, 8 February 2016

2016-02-08T16:19:43Z

←Older revision		Revision as of 16:19, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b24 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 13:20, 10 September 2015

2015-09-10T13:20:05Z

←Older revision		Revision as of 13:20, 10 September 2015
Line 6:		Line 6:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b1x\|2b1x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b1x\|2b1x]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b24 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b24 RCSB], [http://www.ebi.ac.uk/pdbsum/2b24 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b24 OCA], [http://pdbe.org/2b24 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b24 RCSB], [http://www.ebi.ac.uk/pdbsum/2b24 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2b24" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 09:04, 8 January 2015

2015-01-08T09:04:58Z

←Older revision		Revision as of 09:04, 8 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2b24]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B24 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2b24]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B24 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IND:INDOLE'>IND</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IND:INDOLE'>IND</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b1x\|2b1x]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b1x\|2b1x]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b24 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b24 RCSB], [http://www.ebi.ac.uk/pdbsum/2b24 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b24 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b24 RCSB], [http://www.ebi.ac.uk/pdbsum/2b24 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Naphthalene 1,2-dioxygenase]]		[[Category: Naphthalene 1,2-dioxygenase]]
-	[[Category: Rhodococcus sp.]]	+	[[Category: Rhodococcus sp]]
-	[[Category: Allen, C C.]]	+	[[Category: Allen, C C]]
-	[[Category: Gakhar, L.]]	+	[[Category: Gakhar, L]]
-	[[Category: Larkin, M J.]]	+	[[Category: Larkin, M J]]
-	[[Category: Lipscomb, D A.]]	+	[[Category: Lipscomb, D A]]
-	[[Category: Malik, Z A.]]	+	[[Category: Malik, Z A]]
-	[[Category: Ramaswamy, S.]]	+	[[Category: Ramaswamy, S]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Rieske non-heme iron oxygenase]]		[[Category: Rieske non-heme iron oxygenase]]

OCA at 23:56, 29 September 2014

2014-09-29T23:56:12Z

←Older revision		Revision as of 23:56, 29 September 2014
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-	[[~~Image:~~2b24.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of naphthalene 1,2-dioxygenase from Rhodococcus sp. bound to indole==
		+	<StructureSection load='2b24' size='340' side='right' caption='[[2b24]], [[Resolution\|resolution]] 3.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2b24]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B24 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IND:INDOLE'>IND</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b1x\|2b1x]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b24 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b24 RCSB], [http://www.ebi.ac.uk/pdbsum/2b24 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/2b24_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rieske nonheme iron oxygenases form a large class of aromatic ring-hydroxylating dioxygenases found in microorganisms. These enzymes enable microorganisms to tolerate and even exclusively utilize aromatic compounds for growth, making them good candidates for use in synthesis of chiral intermediates and bioremediation. Studies of the chemical stability and thermostability of these enzymes thus become important. We report here the structure of free and substrate (indole)-bound forms of naphthalene dioxygenase from Rhodococcus sp. strain NCIMB12038. The structure of the Rhodococcus enzyme reveals that, despite a approximately 30% sequence identity between these naphthalene dioxygenases, their overall structures superpose very well with a root mean square deviation of less than 1.6 A. The differences in the active site of the two enzymes are pronounced near the entrance; however, indole binds to the Rhodococcus enzyme in the same orientation as in the Pseudomonas enzyme. Circular dichroism spectroscopy experiments show that the Rhodococcus enzyme has higher thermostability than the naphthalene dioxygenase from Pseudomonas species. The Pseudomonas enzyme has an apparent melting temperature of 55 degrees C while the Rhodococcus enzyme does not completely unfold even at 95 degrees C. Both enzymes, however, show similar unfolding behavior in urea, and the Rhodococcus enzyme is only slightly more tolerant to unfolding by guanidine hydrochloride. Structure analysis suggests that the higher thermostability of the Rhodococcus enzyme may be attributed to a larger buried surface area and extra salt bridge networks between the alpha and beta subunits in the Rhodococcus enzyme.

-	~~{{STRUCTURE_2b24\| PDB=2b24 \| SCENE= }}~~	+	Structure and increased thermostability of Rhodococcus sp. naphthalene 1,2-dioxygenase.,Gakhar L, Malik ZA, Allen CC, Lipscomb DA, Larkin MJ, Ramaswamy S J Bacteriol. 2005 Nov;187(21):7222-31. PMID:16237006<ref>PMID:16237006</ref>

-	~~===Crystal structure of naphthalene 1~~,~~2-dioxygenase from Rhodococcus sp~~. ~~bound to indole===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_16237006}}~~	+	==See Also==
-		+	*[[Dioxygenase\|Dioxygenase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~2b24~~]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B24 OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:016237006<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Naphthalene 1,2-dioxygenase]]		[[Category: Naphthalene 1,2-dioxygenase]]
	[[Category: Rhodococcus sp.]]		[[Category: Rhodococcus sp.]]

OCA: Protected "2b24" [edit=sysop:move=sysop]

2013-01-06T09:24:36Z

Protected "2b24" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:24, 6 January 2013

OCA at 09:24, 6 January 2013

2013-01-06T09:24:31Z

←Older revision		Revision as of 09:24, 6 January 2013
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-	{{Seed}}
	[[Image:2b24.png\|left\|200px]]		[[Image:2b24.png\|left\|200px]]

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	{{STRUCTURE_2b24\| PDB=2b24 \| SCENE= }}		{{STRUCTURE_2b24\| PDB=2b24 \| SCENE= }}

	===Crystal structure of naphthalene 1,2-dioxygenase from Rhodococcus sp. bound to indole===		===Crystal structure of naphthalene 1,2-dioxygenase from Rhodococcus sp. bound to indole===

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	{{ABSTRACT_PUBMED_16237006}}		{{ABSTRACT_PUBMED_16237006}}

	==About this Structure==		==About this Structure==
-	~~2B24~~ is a 6 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Rhodococcus_sp.~~_ncimb12038~~ Rhodococcus sp. ~~ncimb12038~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B24 OCA].	+	[[2b24]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B24 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16237006~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016237006</ref><references group="xtra"/>
	[[Category: Naphthalene 1,2-dioxygenase]]		[[Category: Naphthalene 1,2-dioxygenase]]
-	[[Category: Rhodococcus sp. ~~ncimb12038~~]]	+	[[Category: Rhodococcus sp.]]
	[[Category: Allen, C C.]]		[[Category: Allen, C C.]]
	[[Category: Gakhar, L.]]		[[Category: Gakhar, L.]]
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	[[Category: Malik, Z A.]]		[[Category: Malik, Z A.]]
	[[Category: Ramaswamy, S.]]		[[Category: Ramaswamy, S.]]
		+	[[Category: Oxidoreductase]]
	[[Category: Rieske non-heme iron oxygenase]]		[[Category: Rieske non-heme iron oxygenase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:23:44 2009''