2b2s - Revision history

OCA: Redirecting to 5sx0

2016-09-09T16:35:57Z

Redirecting to 5sx0

←Older revision		Revision as of 16:35, 9 September 2016
Line 1:		Line 1:
-	~~==Crystal structure of an oxoferryl species of catalase-peroxidase KATG at pH7.5==~~	+	#REDIRECT [[5sx0]] This PDB entry is obsolete and replaced by 5sx0
-	~~<StructureSection load='2b2s' size='340' side='right' caption='~~[[~~2b2s]], [[Resolution\|resolution]] 2.00Å' scene=''>~~	+
-	~~== Structural highlights ==~~	+
-	~~<table><tr><td colspan='2'>[[2b2s~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pseudomallei"_whitmore_1913 "bacillus pseudomallei" whitmore 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2S FirstGlance]. <br>	+
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr>	+
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mwv\|1mwv]], [[2b2r\|2b2r]], [[2b2q\|2b2q]], [[2b2o\|2b2o]]</td></tr>~~	+
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28450 "Bacillus pseudomallei" Whitmore 1913])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2s OCA], [http://pdbe.org/2b2s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b2s RCSB], [http://www.ebi.ac.uk/pdbsum/2b2s PDBsum]</span></td></tr>	+
-	~~</table>~~	+
-	~~== Evolutionary Conservation ==~~	+
-	~~[[Image:Consurf_key_small.gif\|200px\|right]]~~	+
-	~~Check<jmol>~~	+
-	~~<jmolCheckbox>~~	+
-	~~<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/2b2s_consurf.spt"</scriptWhenChecked>~~	+
-	~~<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>~~	+
-	~~<text>to colour the structure by Evolutionary Conservation</text>~~	+
-	~~</jmolCheckbox>~~	+
-	~~</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method~~ and ~~the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].~~	+
-	~~<div style="clear:both"></div>~~	+
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	The catalase reaction of catalase-peroxidases involves catalase-specific features built into a peroxidase core. An arginine, 20 A from the active-site heme, acts as a molecular switch moving between two conformations, one that activates heme oxidation and one that activates oxoferryl heme reduction by H(2)O(2), facilitating the catalatic pathway in a peroxidase. The influence of the arginine is imparted to the heme through its association with or dissociation from a tyrosinate that modulates reactivity through a Met-Tyr-Trp crosslinked adduct and a pi electron interaction of the heme with the adduct Trp.	+
-		+
-	A molecular switch and electronic circuit modulate catalase activity in catalase-peroxidases.,Carpena X, Wiseman B, Deemagarn T, Singh R, Switala J, Ivancich A, Fita I, Loewen PC EMBO Rep. 2005 Dec;6(12):1156-62. PMID:16211084<ref>PMID:16211084</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 2b2s" style="background-color:#fffaf0;"></div>~~	+
-		+
-	~~==See Also==~~	+
-	*[[Catalase\|Catalase]]	+
-	~~== References ==~~	+
-	~~<references/>~~	+
-	~~__TOC__~~	+
-	~~</StructureSection>~~	+
-	~~[[Category: Bacillus pseudomallei whitmore 1913]]~~	+
-	~~[[Category: Catalase]]~~	+
-	~~[[Category: Carpena, X]]~~	+
-	~~[[Category: Deemagarn, T]]~~	+
-	~~[[Category: Fita, I]]~~	+
-	~~[[Category: Ivancich, A]]~~	+
-	~~[[Category: Loewen, P C]]~~	+
-	~~[[Category: Singh, R]]~~	+
-	~~[[Category: Switala, J]]~~	+
-	~~[[Category: Wiseman, B]]~~	+
-	~~[[Category: Catalase-peroxidase]]~~	+
-	~~[[Category: Compound i]]~~	+
-	~~[[Category: Katg]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Oxoferryl species]]~~	+

OCA at 21:23, 11 September 2015

2015-09-11T21:23:01Z

←Older revision		Revision as of 21:23, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2b2s' size='340' side='right' caption='[[2b2s]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2b2s' size='340' side='right' caption='[[2b2s]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2b2s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Burkholderia_pseudomallei Burkholderia~~ pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2S FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2b2s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pseudomallei"_whitmore_1913 "bacillus pseudomallei" whitmore 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2S FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mwv\|1mwv]], [[2b2r\|2b2r]], [[2b2q\|2b2q]], [[2b2o\|2b2o]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mwv\|1mwv]], [[2b2r\|2b2r]], [[2b2q\|2b2q]], [[2b2o\|2b2o]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28450 ~~Burkholderia~~ pseudomallei])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28450 "Bacillus pseudomallei" Whitmore 1913])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b2s RCSB], [http://www.ebi.ac.uk/pdbsum/2b2s PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2s OCA], [http://pdbe.org/2b2s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b2s RCSB], [http://www.ebi.ac.uk/pdbsum/2b2s PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2b2s" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Burkholderia~~ pseudomallei]]	+	[[Category: Bacillus pseudomallei whitmore 1913]]
	[[Category: Catalase]]		[[Category: Catalase]]
	[[Category: Carpena, X]]		[[Category: Carpena, X]]

OCA at 10:44, 8 January 2015

2015-01-08T10:44:12Z

←Older revision		Revision as of 10:44, 8 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2b2s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2S FirstGlance]. <br>		<table><tr><td colspan='2'>[[2b2s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2S FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mwv\|1mwv]], [[2b2r\|2b2r]], [[2b2q\|2b2q]], [[2b2o\|2b2o]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mwv\|1mwv]], [[2b2r\|2b2r]], [[2b2q\|2b2q]], [[2b2o\|2b2o]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28450 Burkholderia pseudomallei])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28450 Burkholderia pseudomallei])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b2s RCSB], [http://www.ebi.ac.uk/pdbsum/2b2s PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b2s RCSB], [http://www.ebi.ac.uk/pdbsum/2b2s PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 36:
	[[Category: Burkholderia pseudomallei]]		[[Category: Burkholderia pseudomallei]]
	[[Category: Catalase]]		[[Category: Catalase]]
-	[[Category: Carpena, X.]]	+	[[Category: Carpena, X]]
-	[[Category: Deemagarn, T.]]	+	[[Category: Deemagarn, T]]
-	[[Category: Fita, I.]]	+	[[Category: Fita, I]]
-	[[Category: Ivancich, A.]]	+	[[Category: Ivancich, A]]
-	[[Category: Loewen, P C.]]	+	[[Category: Loewen, P C]]
-	[[Category: Singh, R.]]	+	[[Category: Singh, R]]
-	[[Category: Switala, J.]]	+	[[Category: Switala, J]]
-	[[Category: Wiseman, B.]]	+	[[Category: Wiseman, B]]
	[[Category: Catalase-peroxidase]]		[[Category: Catalase-peroxidase]]
	[[Category: Compound i]]		[[Category: Compound i]]

OCA at 03:16, 29 September 2014

2014-09-29T03:16:07Z

←Older revision		Revision as of 03:16, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2b2s.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of an oxoferryl species of catalase-peroxidase KATG at pH7.5==
		+	<StructureSection load='2b2s' size='340' side='right' caption='[[2b2s]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2b2s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2S FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mwv\|1mwv]], [[2b2r\|2b2r]], [[2b2q\|2b2q]], [[2b2o\|2b2o]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28450 Burkholderia pseudomallei])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b2s RCSB], [http://www.ebi.ac.uk/pdbsum/2b2s PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/2b2s_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The catalase reaction of catalase-peroxidases involves catalase-specific features built into a peroxidase core. An arginine, 20 A from the active-site heme, acts as a molecular switch moving between two conformations, one that activates heme oxidation and one that activates oxoferryl heme reduction by H(2)O(2), facilitating the catalatic pathway in a peroxidase. The influence of the arginine is imparted to the heme through its association with or dissociation from a tyrosinate that modulates reactivity through a Met-Tyr-Trp crosslinked adduct and a pi electron interaction of the heme with the adduct Trp.

-	~~{{STRUCTURE_2b2s\| PDB=2b2s \| SCENE= }}~~	+	A molecular switch and electronic circuit modulate catalase activity in catalase-peroxidases.,Carpena X, Wiseman B, Deemagarn T, Singh R, Switala J, Ivancich A, Fita I, Loewen PC EMBO Rep. 2005 Dec;6(12):1156-62. PMID:16211084<ref>PMID:16211084</ref>

-	~~===Crystal structure~~ of ~~an oxoferryl species~~ of ~~catalase-peroxidase KATG at pH7~~.~~5===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16211084}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2b2s]] is a 2 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA].~~	+

	==See Also==		==See Also==
	*[[Catalase\|Catalase]]		*[[Catalase\|Catalase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016211084<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Burkholderia pseudomallei]]		[[Category: Burkholderia pseudomallei]]
	[[Category: Catalase]]		[[Category: Catalase]]

OCA at 20:49, 20 October 2012

2012-10-20T20:49:30Z

←Older revision		Revision as of 20:49, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2b2s]] is a 2 chain structure ~~of [[Catalase]]~~ with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA].	+	[[2b2s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA].

	==See Also==		==See Also==

OCA: Protected "2b2s" [edit=sysop:move=sysop]

2012-07-27T11:45:08Z

Protected "2b2s" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:45, 27 July 2012

OCA at 11:45, 27 July 2012

2012-07-27T11:45:06Z

←Older revision		Revision as of 11:45, 27 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2b2s.png\|left\|200px]]		[[Image:2b2s.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2b2s", creates the "Structure Box" on the page.
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	{{STRUCTURE_2b2s\| PDB=2b2s \| SCENE= }}		{{STRUCTURE_2b2s\| PDB=2b2s \| SCENE= }}

	===Crystal structure of an oxoferryl species of catalase-peroxidase KATG at pH7.5===		===Crystal structure of an oxoferryl species of catalase-peroxidase KATG at pH7.5===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16211084}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16211084 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16211084}}		{{ABSTRACT_PUBMED_16211084}}

	==About this Structure==		==About this Structure==
-	~~2B2S~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA].	+	[[2b2s]] is a 2 chain structure of [[Catalase]] with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA].
		+
		+	==See Also==
		+	*[[Catalase\|Catalase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16211084~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016211084</ref><references group="xtra"/>
	[[Category: Burkholderia pseudomallei]]		[[Category: Burkholderia pseudomallei]]
	[[Category: Catalase]]		[[Category: Catalase]]
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	[[Category: Compound i]]		[[Category: Compound i]]
	[[Category: Katg]]		[[Category: Katg]]
		+	[[Category: Oxidoreductase]]
	[[Category: Oxoferryl species]]		[[Category: Oxoferryl species]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:23:19 2009''

OCA at 03:23, 18 February 2009

2009-02-18T03:23:21Z

←Older revision		Revision as of 03:23, 18 February 2009
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	==About this Structure==		==About this Structure==
-	2B2S is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA].	+	2B2S is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2S OCA].

	==Reference==		==Reference==
-	A molecular switch and electronic circuit modulate catalase activity in catalase-peroxidases., Carpena X, Wiseman B, Deemagarn T, Singh R, Switala J, Ivancich A, Fita I, Loewen PC, EMBO Rep. 2005 Dec;6(12):1156-62. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16211084 16211084]~~	+	<ref group="xtra">PMID:16211084</ref><references group="xtra"/>
	[[Category: Burkholderia pseudomallei]]		[[Category: Burkholderia pseudomallei]]
	[[Category: Catalase]]		[[Category: Catalase]]
-	[[Category: Single protein]]
	[[Category: Carpena, X.]]		[[Category: Carpena, X.]]
	[[Category: Deemagarn, T.]]		[[Category: Deemagarn, T.]]
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	[[Category: Oxoferryl species]]		[[Category: Oxoferryl species]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 29 12~~:04:~~48 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:23:19 2009''

OCA at 09:04, 29 July 2008

2008-07-29T09:04:49Z

←Older revision		Revision as of 09:04, 29 July 2008
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-	[[Image:2b2s.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2b2s.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2b2s\| PDB=2b2s \| SCENE= }}		{{STRUCTURE_2b2s\| PDB=2b2s \| SCENE= }}

-	~~'''~~Crystal structure of an oxoferryl species of catalase-peroxidase KATG at pH7.5~~'''~~	+	===Crystal structure of an oxoferryl species of catalase-peroxidase KATG at pH7.5===


-	~~==Overview==~~	+	<!--
-	The ~~catalase reaction of catalase-peroxidases involves catalase-specific features built into a peroxidase core. An arginine~~, ~~20 A from~~ the ~~active-site heme, acts~~ as ~~a molecular switch moving between two conformations, one that activates heme oxidation and one that activates oxoferryl heme reduction by H(2)O(2~~), ~~facilitating~~ the ~~catalatic pathway in a peroxidase~~. ~~The influence of the arginine is imparted to the heme through its association with or dissociation from a tyrosinate that modulates reactivity through a Met~~-~~Tyr~~-~~Trp crosslinked adduct and a pi electron interaction of the heme with the adduct Trp.~~	+	The line below this paragraph, {{ABSTRACT_PUBMED_16211084}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 16211084 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_16211084}}

	==About this Structure==		==About this Structure==
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	[[Category: Katg]]		[[Category: Katg]]
	[[Category: Oxoferryl species]]		[[Category: Oxoferryl species]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 19~~:46:39 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:04:48 2008''

OCA at 16:46, 3 May 2008

2008-05-03T16:46:41Z

←Older revision		Revision as of 16:46, 3 May 2008
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	[[Image:2b2s.gif\|left\|200px]]		[[Image:2b2s.gif\|left\|200px]]

-	~~{{Structure~~	+	<!--
-	~~\|PDB= 2b2s \|SIZE=350\|CAPTION=~~ <~~scene name='initialview01'>2b2s</scene>, resolution 2.00Å~~	+	The line below this paragraph, containing "STRUCTURE_2b2s", creates the "Structure Box" on the page.
-	~~\|SITE=~~	+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	~~\|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>~~, ~~<scene name='pdbligand=NA:SODIUM+ION'>NA</scene>~~, ~~<scene name='pdbligand=O:OXYGEN+ATOM'>O</scene>~~	+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	~~\|ACTIVITY= <span class='plainlinks'>[http://en~~.~~wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span>~~	+	or leave the SCENE parameter empty for the default display.
-	~~\|GENE= katG~~ (~~[http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28450 Burkholderia pseudomallei]~~)	+	-->
-	~~\|DOMAIN=~~	+	{{STRUCTURE_2b2s\| PDB=2b2s \| SCENE= }}
-	~~\|RELATEDENTRY=[[1mwv\|1MWV]]~~, ~~[[2b2r\|2B2R]], [[2b2q\|2B2Q]], [[2b2o\|2B2O]]~~	+
-	~~\|RESOURCES=<span class='plainlinks'>[http://oca~~.~~weizmann.ac.il/oca~~-~~docs/fgij/fg.htm?mol=2b2s FirstGlance], [http://oca.weizmann.ac.il/oca~~-~~bin/ocaids?id~~=2b2s ~~OCA], [http://www.ebi.ac.uk/pdbsum/2b2s PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId~~=~~2b2s RCSB]</span>~~	+
-	}}	+

	'''Crystal structure of an oxoferryl species of catalase-peroxidase KATG at pH7.5'''		'''Crystal structure of an oxoferryl species of catalase-peroxidase KATG at pH7.5'''
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	[[Category: Switala, J.]]		[[Category: Switala, J.]]
	[[Category: Wiseman, B.]]		[[Category: Wiseman, B.]]
-	[[Category: ~~catalase~~-peroxidase]]	+	[[Category: Catalase-peroxidase]]
-	[[Category: ~~compound~~ i]]	+	[[Category: Compound i]]
-	[[Category: ~~katg~~]]	+	[[Category: Katg]]
-	[[Category: ~~oxoferryl~~ species]]	+	[[Category: Oxoferryl species]]
-		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 19:46:39 2008''
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Mar 31 02~~:00:38 2008''	+