2b5y - Revision history

OCA at 11:20, 22 May 2024

2024-05-22T11:20:12Z

←Older revision		Revision as of 11:20, 22 May 2024
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	==Solution Structure of a Thioredoxin-like Protein in the Oxidized Form==		==Solution Structure of a Thioredoxin-like Protein in the Oxidized Form==
-	<StructureSection load='2b5y' size='340' side='right'caption='[[2b5y~~]], [[NMR_Ensembles_of_Models \| 11 NMR models~~]]' scene=''>	+	<StructureSection load='2b5y' size='340' side='right'caption='[[2b5y]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"vibrio_subtilis"_ehrenberg_1835 "vibrio~~ subtilis~~" ehrenberg 1835~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'>[[2b5x\|2b5x]]</div~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5y OCA], [https://pdbe.org/2b5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b5y RCSB], [https://www.ebi.ac.uk/pdbsum/2b5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b5y ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5y OCA], [https://pdbe.org/2b5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b5y RCSB], [https://www.ebi.ac.uk/pdbsum/2b5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b5y ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/YKUV_BACSU YKUV_BACSU] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Vibrio~~ subtilis ~~ehrenberg 1835~~]]	+	[[Category: Bacillus subtilis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Jin, C]]	+	[[Category: Jin C]]
-	[[Category: Xia, B]]	+	[[Category: Xia B]]
-	[[Category: Zhang, X]]	+	[[Category: Zhang X]]
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Thioredoxin-like~~]]	+

OCA at 06:46, 10 November 2021

2021-11-10T06:46:38Z

←Older revision		Revision as of 06:46, 10 November 2021
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	<StructureSection load='2b5y' size='340' side='right'caption='[[2b5y]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>		<StructureSection load='2b5y' size='340' side='right'caption='[[2b5y]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b5x\|2b5x]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2b5x\|2b5x]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2b5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5y OCA], [~~http~~://pdbe.org/2b5y PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2b5y RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2b5y PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2b5y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5y OCA], [https://pdbe.org/2b5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b5y RCSB], [https://www.ebi.ac.uk/pdbsum/2b5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b5y ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:54, 19 February 2020

2020-02-19T07:54:44Z

←Older revision		Revision as of 07:54, 19 February 2020
Line 1:		Line 1:

	==Solution Structure of a Thioredoxin-like Protein in the Oxidized Form==		==Solution Structure of a Thioredoxin-like Protein in the Oxidized Form==
-	<StructureSection load='2b5y' size='340' side='right' caption='[[2b5y]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>	+	<StructureSection load='2b5y' size='340' side='right'caption='[[2b5y]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Vibrio subtilis ehrenberg 1835]]		[[Category: Vibrio subtilis ehrenberg 1835]]
		+	[[Category: Large Structures]]
	[[Category: Jin, C]]		[[Category: Jin, C]]
	[[Category: Xia, B]]		[[Category: Xia, B]]

OCA at 06:12, 16 May 2018

2018-05-16T06:12:46Z

←Older revision		Revision as of 06:12, 16 May 2018
Line 1:		Line 1:
		+
	==Solution Structure of a Thioredoxin-like Protein in the Oxidized Form==		==Solution Structure of a Thioredoxin-like Protein in the Oxidized Form==
	<StructureSection load='2b5y' size='340' side='right' caption='[[2b5y]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>		<StructureSection load='2b5y' size='340' side='right' caption='[[2b5y]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"~~bacillus_globigii~~"~~_migula_1900~~ "~~bacillus globigii~~" ~~migula 1900~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b5x\|2b5x]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b5x\|2b5x]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5y OCA], [http://pdbe.org/2b5y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b5y RCSB], [http://www.ebi.ac.uk/pdbsum/2b5y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5y OCA], [http://pdbe.org/2b5y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b5y RCSB], [http://www.ebi.ac.uk/pdbsum/2b5y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2b5y ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b5/2b5y_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b5/2b5y_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b5y ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 29:		Line 30:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus globigii migula 1900~~]]	+	[[Category: Vibrio subtilis ehrenberg 1835]]
	[[Category: Jin, C]]		[[Category: Jin, C]]
	[[Category: Xia, B]]		[[Category: Xia, B]]

OCA at 02:02, 12 September 2015

2015-09-12T02:02:03Z

←Older revision		Revision as of 02:02, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='2b5y' size='340' side='right' caption='[[2b5y]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>		<StructureSection load='2b5y' size='340' side='right' caption='[[2b5y]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_subtilis Bacillus subtilis~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b5x\|2b5x]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b5x\|2b5x]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b5y RCSB], [http://www.ebi.ac.uk/pdbsum/2b5y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5y OCA], [http://pdbe.org/2b5y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b5y RCSB], [http://www.ebi.ac.uk/pdbsum/2b5y PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2b5y" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus ~~subtilis~~]]	+	[[Category: Bacillus globigii migula 1900]]
	[[Category: Jin, C]]		[[Category: Jin, C]]
	[[Category: Xia, B]]		[[Category: Xia, B]]

OCA at 09:57, 8 January 2015

2015-01-08T09:57:21Z

←Older revision		Revision as of 09:57, 8 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b5x\|2b5x]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b5x\|2b5x]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b5y RCSB], [http://www.ebi.ac.uk/pdbsum/2b5y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b5y RCSB], [http://www.ebi.ac.uk/pdbsum/2b5y PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
-	[[Category: Jin, C.]]	+	[[Category: Jin, C]]
-	[[Category: Xia, B.]]	+	[[Category: Xia, B]]
-	[[Category: Zhang, X.]]	+	[[Category: Zhang, X]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Thioredoxin-like]]		[[Category: Thioredoxin-like]]

OCA at 02:22, 30 September 2014

2014-09-30T02:22:07Z

←Older revision		Revision as of 02:22, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2b5y.~~png~~\|~~left~~\|200px]]	+	==Solution Structure of a Thioredoxin-like Protein in the Oxidized Form==
		+	<StructureSection load='2b5y' size='340' side='right' caption='[[2b5y]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2b5y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B5Y FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2b5x\|2b5x]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b5y RCSB], [http://www.ebi.ac.uk/pdbsum/2b5y PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b5/2b5y_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Bacillus subtilis YkuV responds to environmental oxidative stress and plays an important role for the bacteria to adapt to the environment. Bioinformatic analysis suggests that YkuV is a homolog of membrane-anchored proteins and belongs to the thioredoxin-like protein superfamily containing the typical Cys-Xaa-Xaa-Cys active motif. However, the biological function of this protein remains unknown thus far. In order to elucidate the biological function, we have determined the solution structures of both the oxidized and reduced forms of B. subtilis YkuV by NMR spectroscopy and performed biochemical studies. Our results demonstrated that the reduced YkuV has a low midpoint redox potential, allowing it to reduce a variety of protein substrates. The overall structures of both oxidized and reduced forms are similar, with a typical thioredoxin-like fold. However, significant conformational changes in the Cys-Xaa-Xaa-Cys active motif of the tertiary structures are observed between the two forms. In addition, the backbone dynamics provide further insights in understanding the strong redox potential of the reduced YkuV. Furthermore, we demonstrated that YkuV is able to reduce different protein substrates in vitro. Together, our results clearly established that YkuV may function as a general thiol:disulfide oxidoreductase, which acts as an alternative for thioredoxin or thioredoxin reductase to maintain the reducing environment in the cell cytoplasm.

-	~~{{STRUCTURE_2b5y\| PDB=2b5y \| SCENE= }}~~	+	The Bacillus subtilis YkuV is a thiol:disulfide oxidoreductase revealed by its redox structures and activity.,Zhang X, Hu Y, Guo X, Lescop E, Li Y, Xia B, Jin C J Biol Chem. 2006 Mar 24;281(12):8296-304. Epub 2006 Jan 17. PMID:16418167<ref>PMID:16418167</ref>

-	~~===Solution Structure~~ of ~~a Thioredoxin-like Protein in~~ the ~~Oxidized Form===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16418167}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2b5y]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_subtilis Bacillus subtilis]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016418167<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Jin, C.]]		[[Category: Jin, C.]]

OCA: Protected "2b5y" [edit=sysop:move=sysop]

2013-01-06T11:34:57Z

Protected "2b5y" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:34, 6 January 2013

OCA at 11:34, 6 January 2013

2013-01-06T11:34:54Z

←Older revision		Revision as of 11:34, 6 January 2013
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-	{{Seed}}
	[[Image:2b5y.png\|left\|200px]]		[[Image:2b5y.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2b5y", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2b5y\| PDB=2b5y \| SCENE= }}		{{STRUCTURE_2b5y\| PDB=2b5y \| SCENE= }}

	===Solution Structure of a Thioredoxin-like Protein in the Oxidized Form===		===Solution Structure of a Thioredoxin-like Protein in the Oxidized Form===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16418167}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16418167 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_16418167}}		{{ABSTRACT_PUBMED_16418167}}

	==About this Structure==		==About this Structure==
-	~~2B5Y~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA].	+	[[2b5y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16418167~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016418167</ref><references group="xtra"/>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Jin, C.]]		[[Category: Jin, C.]]
	[[Category: Xia, B.]]		[[Category: Xia, B.]]
	[[Category: Zhang, X.]]		[[Category: Zhang, X.]]
		+	[[Category: Oxidoreductase]]
	[[Category: Thioredoxin-like]]		[[Category: Thioredoxin-like]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:39:53 2009''

OCA at 07:39, 18 February 2009

2009-02-18T07:39:55Z

←Older revision		Revision as of 07:39, 18 February 2009
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	==About this Structure==		==About this Structure==
-	2B5Y is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA].	+	2B5Y is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5Y OCA].

	==Reference==		==Reference==
-	The Bacillus subtilis YkuV is a thiol:disulfide oxidoreductase revealed by its redox structures and activity., Zhang X, Hu Y, Guo X, Lescop E, Li Y, Xia B, Jin C, J Biol Chem. 2006 Mar 24;281(12):8296-304. Epub 2006 Jan 17. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16418167 16418167]~~	+	<ref group="xtra">PMID:16418167</ref><references group="xtra"/>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
-	[[Category: Single protein]]
	[[Category: Jin, C.]]		[[Category: Jin, C.]]
	[[Category: Xia, B.]]		[[Category: Xia, B.]]
Line 31:		Line 30:
	[[Category: Thioredoxin-like]]		[[Category: Thioredoxin-like]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 29 15~~:57:~~48 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:39:53 2009''